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HOW I MANAGE IT
DR. HANISH BABU, MDDR. HANISH BABU, MD
Dermatologist & VenereologistDermatologist & Venereologist
City Medical Centre, Ajman, UAECity Medical Centre, Ajman, UAE
Read about: How to Get Rid of Seborrheic Dermatitis
Copyright Dr.Hanish Babu, MD, 2009
THE DEFINITION
Seborrhoeic Dermatitis is a hyperproliferative
disorder of the epidermis in the sebaceous rich areas
of the body associated with increased and altered
sebum production and yeast colonization.
Read about: How to Get Rid of Seborrheic Dermatitis
THE QUESTION:
Is the increased sebum production the primary
event?
Does the Malassezia colonization lead to increased
sebum production?
Read about: How to Get Rid of Seborrheic Dermatitis
MALASSEZIA & SEBORRHEIC DERMATITIS
Malassezia globosa; M.restrictaMalassezia globosa; M.restricta
Digestion of Seb.Tg
Release of Oleic Acid
Penetrate Str.Corneum
Alternate pathway activnAlternate pathway activn
Barrier CompromisedBarrier Compromised
Increased Sebum
Dermatitis
Hyperproliferation
Repair Process
Dr.Hanish Babu, MD, 2009
Genetic Predisposition
Seborrheic DiathesisSeborrheic Diathesis
Stress, Fatigue
Environmental
Hormonal
Immune Def,
Imm.alterations
?Food
Alcohol
Drugs
Diseases
SebumSebum
MalasseziaMalassezia
Sebum alteration
Alternate Complement
Pathway
Inflammation
Hyperproliferation &
dermatitis
Mild –Moderate-Severe
Dandruff
Mild Moderate Severe
Seborrheic Dermatitis
Psoriasis overlap
Seborrhiasis
Read about: How to Get Rid of Seborrheic Dermatitis
DIFFERENTIAL DIAGNOSIS
Scalp: Contact Dermatitis, Psoriasis, Atopic
Dermatitis, Infective Dermatitis 2ry to Pediculosis
Ear Canal: Otomycosis,Psoriasis,Contact Dermatitis
Face: Rosacia,Contact Dermatitis,Psoriasis,Impetigo,
2ry Syphilis,Drug eruptions
Chest and Back: Psoriasis, Pityriasis Rosea,Contact
Dermatitis,Drug Eruptions
Drug Eruptions: OCP, Systemic Steroids,
Androgens, auranofin, aurothioglucose, buspirone,
chlorpromazine, cimetidine, ethionamide, gold,
griseofulvin, haloperidol, interferon alfa, lithium,
methyldopa, phenothiazines, psoralens, beta
blockers,stanozolol, thiothixene.
DISEASE ASSOCIATED WITH
SEBORRHOEIC DERMATITIS
Parkinsonism
Other Neurological: Epilepsy, Idiopathic Post
Encephalitis syndrome
Immune deficiency: HIV, neoplasms, drug induced.
Immune Alterations: C5 deficiency: Leiner’s
Letterer Siwe: Scaling scalp with petechiae
Read about: How to Get Rid of Seborrheic Dermatitis
PRINCIPLES OF MANAGEMENT
Patient educationPatient education
No Cure. Like dental care: daily attention.
Regular Washing of scalp
Anti seborrhoeic treatment alternating with normql
shampooing
Hair tonics & tinctures with alcohol base:
Aggravate
Normal Soap & Shaving Creams: Use emollients and
emollient soap substitutes
Alter Food Habits: low fat, low sugar diet ;cut down
on the alcohol.
Manage Stress
MANAGEMENT
1. Regulation of Hyper-Seborrhea
 Control Of Dietary Habits
 Stress Management
 Regular Washing without causing irritation
 Avoidance of offending drug, alcohol
 Usage of creams containing antiseborrhoeic agents:
 Zinc Acetyl Methionate,
 Undecylenic Acid Derivatives
 Other antifungal creams and solutions to control
Malassezia
Read about: How to Get Rid of Seborrheic Dermatitis
MANAGEMENT
2. Control of the Yeast
 Imidazole solutions or creams: 2-3 times a week
 Antifungal shampoos: Daily till control,
then weekly twice.(Ketoconazole, Zinc
Pyrethrone,Cyclopirox,Undecylenic acid etc)
 Regular Washing
 Other shampoos: containing Tar ,Salicylic acid or
selenium sulphide
 Avoidance of offending drug, alcohol
 Control of Seborrhoea
Read about: How to Get Rid of Seborrheic Dermatitis
MANAGEMENT
3. Removal Of Thick Scales
 Overnight application of tar/urea/salicylic acid
containing creams
 Rubbing with warm mineral oil and washing off
 If crusting and oozing: A course of antibiotic
with a steroid-antifungal cream for 5-7
days;once scales and 2ry infection is cleared;
start antimalassezia treatment
Read about: How to Get Rid of Seborrheic Dermatitis
MANAGEMENT
4. Severe and Un-responsive Cases
 1- 2 Weeks’ course of systemic antiyeast
treatment with Ketoconazole,Itraconazole or
Fluconazole
 Class IV or lower strength topical steroid
creams, lotions or solutions for acute flares
for 5-7 days only.
 Continue with anti seborrhoeic/ antiyeast
measures
 Other alternatives: Calcineurin derivatives
Pimecrolimus/tacrolimus, metronidazole gel,
Narrow band UVB therapy etc.
Read about: How to Get Rid of Seborrheic Dermatitis
Read about: How to Get Rid of Dandruff
Copyright Dr.Hanish Babu, MD, 2009

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How to Get Rid of Seborrheic Dermatitis

  • 1. HOW I MANAGE IT DR. HANISH BABU, MDDR. HANISH BABU, MD Dermatologist & VenereologistDermatologist & Venereologist City Medical Centre, Ajman, UAECity Medical Centre, Ajman, UAE Read about: How to Get Rid of Seborrheic Dermatitis Copyright Dr.Hanish Babu, MD, 2009
  • 2. THE DEFINITION Seborrhoeic Dermatitis is a hyperproliferative disorder of the epidermis in the sebaceous rich areas of the body associated with increased and altered sebum production and yeast colonization. Read about: How to Get Rid of Seborrheic Dermatitis
  • 3. THE QUESTION: Is the increased sebum production the primary event? Does the Malassezia colonization lead to increased sebum production? Read about: How to Get Rid of Seborrheic Dermatitis
  • 4. MALASSEZIA & SEBORRHEIC DERMATITIS Malassezia globosa; M.restrictaMalassezia globosa; M.restricta Digestion of Seb.Tg Release of Oleic Acid Penetrate Str.Corneum Alternate pathway activnAlternate pathway activn Barrier CompromisedBarrier Compromised Increased Sebum Dermatitis Hyperproliferation Repair Process Dr.Hanish Babu, MD, 2009
  • 5. Genetic Predisposition Seborrheic DiathesisSeborrheic Diathesis Stress, Fatigue Environmental Hormonal Immune Def, Imm.alterations ?Food Alcohol Drugs Diseases SebumSebum MalasseziaMalassezia Sebum alteration Alternate Complement Pathway Inflammation Hyperproliferation & dermatitis
  • 6. Mild –Moderate-Severe Dandruff Mild Moderate Severe Seborrheic Dermatitis Psoriasis overlap Seborrhiasis Read about: How to Get Rid of Seborrheic Dermatitis
  • 7. DIFFERENTIAL DIAGNOSIS Scalp: Contact Dermatitis, Psoriasis, Atopic Dermatitis, Infective Dermatitis 2ry to Pediculosis Ear Canal: Otomycosis,Psoriasis,Contact Dermatitis Face: Rosacia,Contact Dermatitis,Psoriasis,Impetigo, 2ry Syphilis,Drug eruptions Chest and Back: Psoriasis, Pityriasis Rosea,Contact Dermatitis,Drug Eruptions Drug Eruptions: OCP, Systemic Steroids, Androgens, auranofin, aurothioglucose, buspirone, chlorpromazine, cimetidine, ethionamide, gold, griseofulvin, haloperidol, interferon alfa, lithium, methyldopa, phenothiazines, psoralens, beta blockers,stanozolol, thiothixene.
  • 8. DISEASE ASSOCIATED WITH SEBORRHOEIC DERMATITIS Parkinsonism Other Neurological: Epilepsy, Idiopathic Post Encephalitis syndrome Immune deficiency: HIV, neoplasms, drug induced. Immune Alterations: C5 deficiency: Leiner’s Letterer Siwe: Scaling scalp with petechiae Read about: How to Get Rid of Seborrheic Dermatitis
  • 9. PRINCIPLES OF MANAGEMENT Patient educationPatient education No Cure. Like dental care: daily attention. Regular Washing of scalp Anti seborrhoeic treatment alternating with normql shampooing Hair tonics & tinctures with alcohol base: Aggravate Normal Soap & Shaving Creams: Use emollients and emollient soap substitutes Alter Food Habits: low fat, low sugar diet ;cut down on the alcohol. Manage Stress
  • 10. MANAGEMENT 1. Regulation of Hyper-Seborrhea  Control Of Dietary Habits  Stress Management  Regular Washing without causing irritation  Avoidance of offending drug, alcohol  Usage of creams containing antiseborrhoeic agents:  Zinc Acetyl Methionate,  Undecylenic Acid Derivatives  Other antifungal creams and solutions to control Malassezia Read about: How to Get Rid of Seborrheic Dermatitis
  • 11. MANAGEMENT 2. Control of the Yeast  Imidazole solutions or creams: 2-3 times a week  Antifungal shampoos: Daily till control, then weekly twice.(Ketoconazole, Zinc Pyrethrone,Cyclopirox,Undecylenic acid etc)  Regular Washing  Other shampoos: containing Tar ,Salicylic acid or selenium sulphide  Avoidance of offending drug, alcohol  Control of Seborrhoea Read about: How to Get Rid of Seborrheic Dermatitis
  • 12. MANAGEMENT 3. Removal Of Thick Scales  Overnight application of tar/urea/salicylic acid containing creams  Rubbing with warm mineral oil and washing off  If crusting and oozing: A course of antibiotic with a steroid-antifungal cream for 5-7 days;once scales and 2ry infection is cleared; start antimalassezia treatment Read about: How to Get Rid of Seborrheic Dermatitis
  • 13. MANAGEMENT 4. Severe and Un-responsive Cases  1- 2 Weeks’ course of systemic antiyeast treatment with Ketoconazole,Itraconazole or Fluconazole  Class IV or lower strength topical steroid creams, lotions or solutions for acute flares for 5-7 days only.  Continue with anti seborrhoeic/ antiyeast measures  Other alternatives: Calcineurin derivatives Pimecrolimus/tacrolimus, metronidazole gel, Narrow band UVB therapy etc.
  • 14. Read about: How to Get Rid of Seborrheic Dermatitis Read about: How to Get Rid of Dandruff Copyright Dr.Hanish Babu, MD, 2009

Notas do Editor

  1. To start with, a working definition as a basis for building up the treatment protocol should be:Seborrhoeic Dermatitis is a hyperproliferative disorder of the epidermis of sebaceous rich areas associated with increased and altered sebum production and yeast colonization.
  2. A severe, explosive onset of seborrheic dermatitis may be a marker for HIV infection, regardless of age. It may appear as a butterfly rash, similar to the acute facial eruption associated with systemic lupus erythematosus. The dermatitis appears early in persons with AIDS, affects 25-50% of persons with AIDS, and has greater involvement and greater activity in those with diminished T-cell function.