2. Learning Objectives
How do rate-of-living theories explain aging?
What are the major hypotheses in cellular theories of
aging?
How do programmed cell death theories propose that we
age?
How do the basic developmental forces interact in
biological and physiological aging?
3. Rate-of-Living Theories
Limited energy
Organisms have only so much energy to expend in a lifetime
Metabolic rate of certain animals seem to be correlated to their lifespan
Excess calories
Reduction in calorie intake increases lifespan
Okinawans consume 60% less; have 40 times more centenarians
Hormonal regulatory system adaptation to stress
Age which a mammal becomes mature is related to longevity
Metabolism relates directly to longevity
Saving your energy won’t directly
result in living longer
4. Cellular Theories
Limited number of times a cell can divide
(Hayflick limit)
Cross-linking
Tissue becomes stiffer with age
Free radicals
Reactive chemicals causing cellular damage
5. Programmed Cell Death Theories
Aging programmed into genetic code?
Cells pre-programmed to self-destruct
Other genetic pathologies:
Osteoarthritis
Changes in the brain cells
Alzheimer’s
Memory loss
Personality changes
6. Implications of the Developmental Forces
The biological, psychological, sociocultural, and
lifecycle forces
Unified theory not yet developed
Three general approaches to slowing or reversing
the aging process:
1. Delay the chronic illnesses of old age
2. Slow the fundamental processes of aging to increase life span
3. Arrest or reverse aging by removing the damage caused by the
metabolic process
7. Learning Objectives
How do our skin, hair, and voices change with age?
What happens to our body build with age?
What age-related changes occur in our ability to move
around?
8. Changes in Skin, Hair, and Voice
Changes in Skin
Why does our skin wrinkle?
Four-step process
Effects of sun exposure on skin
Sun exposure & smoking
How to counteract these effects?
Other skin changes
Pigment-containing cells decrease
Age spots, moles
Varicose veins
9. Changes in the Hair
Individual differences
Gender differences
Hair loss caused by destruction of germ centers that produce
hair follicles
Graying caused by cessation of pigment production
Other hair changes
Males do not lose facial hair.
Females gain facial hair. (hormonal changes)
10. Changes in the Voice
Differences in young and old voices
Lowering in pitch
Increased breathlessness and trembling
Slower and less pronounced pronunciation
Decreased volume
Normative changes or poor health?
What do you think?
11. Changes in Body Build
Differences in the way bodies look over time
Decrease in height and fluctuations in weight
Between mid-50s and mid-70s men lose about 1 inch and women 2 inches
Compression of the spine
Changes in posture
Weight gain then loss
How different between men and women?
12. Changes in Mobility
Muscles
Strength loss: age 70 – up to 20%; age 80 – up to 40%
No difference in the rate of muscle change between men and
women
Bones
Loss begins in the late 30s, accelerates in the 50s, and slows in 70s
Gender differences
Osteoporosis: leading cause of broken bones in older women
Joints
Osteoarthritis
Rheumatoid arthritis
15. Psychological Implications
Gender differences
Compensation
Cosmetics
Hair dyes
Plastic surgery
Appearance vs. actual losses in strength and
endurance
Exercise and resistance training is useful up to age 90
Adaptive behaviors
Pain in the joints may reduce mobility
Rehabilitation after hip fractures
16. Learning Objectives
What age-related changes happen in vision?
How does hearing change as people age?
What age-related changes occur in the sense of touch and
balance?
What happens to taste and smell with increasing age?
17. Vision
Structural changes in the eye
Adaptation – light and dark; change focus
Presbyopia
Cataracts – opaque spots on the lens
Glaucoma - high pressure in fluid around eye
Retinal Changes
Macular degeneration
- progressive and irreversible destruction
of receptors (loss of details)
Diabetic retinopathy
- aging of the arteries
- blindness
20. Classroom Participation Measure
1. Take out a piece of paper
2. Put your name in the right top corner
3. Without talking answer the visual puzzle on
the next slide
20 of 40
22. Psychological Effects of Visual Changes
Reading
TV watching
Grocery labels; cooking instructions
Driving a car
Corrective actions
Glasses (Presbyopia)
Surgery (cataracts)
Corrective environmental changes
Brighter lights
Larger type
23. Hearing
Damage due to loud environment
Cumulative effects
Single incident damage
Presbycusis – reduced sensitivity to high pitched tones
Most common hearing problem
On increase among young adults
Social adjustment to hearing loss
Loss of independence, social isolation
Irritation, paranoia, depression
Emotional effects
Decreased quality of life
Corrective action (next slide)
24.
25. Atrophy
The wasting
away of a
body part
Decatur Daily Ad - Sept 5, 2010
26.
27. Somesthesia and Balance
Loss of touch
Temperature regulation
Pain sensitivity
Kinesthesis
Where is your body?
Reduced quality of life
28. “Weebles wobble,
but they don’t fall
Balance down!”
Vestibular system
Dizziness, lightheaded, vertigo
Longer time to integrate all sensory information
Fear of falling
Environmental hazards
Loose rugs
Slippery floors
Lighting
Hip protection
Tai-Chi
Enhance body awareness
Improve balance
Reduce falls
29. Taste and Smell
Too old to cut the mustard?
Taste dependent on smell
Safety factors
Personal hygiene
Memory differences between odors and other
memory cues
30. Learning Objectives
What age-related changes occur in the cardiovascular
system? What types of cardiovascular disease are common
in adult development and aging? Psychological effects?
What structural and functional changes occur with age in
the respiratory system? What are the most common types
of respiratory diseases in older adults? Psychological
effects?
31. Cardiovascular System
Underlying cause of diminished capacity
Accumulation of fat deposits
Stiffening of the heart muscle
Decline in aerobic capacity
By age 65 - 60 to 70% decline
Get tired easily
Heart attaches while performing
moderately exerting tasks
Want to decline less?
Stay in shape during adulthood
32. Cardiovascular Disease
Ethnic and gender differences—Why?
Congestive heart failure (most common hospitalization over 65)
Angina pectoris (decrease oxygen to the heart, causing pain)
Myocardial infarction (MI) (heart attack)
Atherosclerosis (build up of fat and calcium in artery walls)
Hypertension
Cerebrovascular accident (CVA) (stroke)
33.
34. Respiratory System
Respiratory Diseases
Chronic obstructive pulmonary disease (COPD)
Damage is irreversible
Emphysema
82% self-induced by smoking
Chronic bronchitis
More common with people over 45
Dust, irritating fumes, air pollution
35. Learning Objectives
What reproductive changes occur in women?
What reproductive changes occur in men?
What are the psychological effects of reproductive
changes?
36. Female Reproductive System
Genital organ change begins in the 40s
Transition – perimenopause
Changes in reproductive organs and sexual functioning
Menopause
Ethnic differences in the severity of symptoms
Progressive change after menopause
Hormone Replacement Therapy (HRT)
No physiological reason why most women cannot continue
sexual activity into old age.
37. Male Reproductive System
Unlike menopause, no event to mark changes
Decline in testosterone levels
Decrease in sperm production (30% between 30 and 60)
Prostate cancer a real threat
Impotence: normally treatable with drugs
Erectile Dysfunction: treatable with Viagra, Cialis, and Levitra
Psychological Implications
For healthy adults males, sexual activity is lifelong option.
Stereotyping has important consequences.
38. Learning Objectives
How do we measure changes in the brain?
What major changes occur in neurons? How do neurons’
ability to communicate with each other change with age?
What are the psychological effects of changes in the brain?
What major changes occur in the autonomic nervous system?
41. Neurons (individual cells)
Dendrites – carry message towards cell
Cell body
Axon – carry message away from cell
Terminal branches
Neurotransmitters
Synapse
5 Min
41 of 40
42.
43. Structural Changes in Neurons
Plasticity (capability of brain to adapt its function and structure)
Neurofibrillary Tangles (fibers of the axon become tangled)
Amyloid Plaques (damaged & dying neurons around a core of protein)
Both considered characteristics of Alzheimer’s disease
Changes in communication between neurons
Parkinson’s disease
Tremors
Rigidity
Difficulty keeping balance
Shuffling walking style
44. Autonomic Nervous System
Regulating Body Temperature
Elderly susceptible to hypothermia
Don’t notice they are cold
Less ability to raise body temperature
Sleep and Aging
Less sleep
Day napping
Moody, poorer function, fatigue, decrease motivation &
concentration
45. Psychological Implications
Senility – What is it?
Decline in cognitive functioning
Dementia is not part of normal aging
Successful Aging
Adapting to changes (physically & mentally)
Normal Aging
expected changes that all experience
Pathological Aging
due to disease process