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SLEEP
BIOLOGICAL CLOCKS
 Circadian rhythms – daily
  cycles of ~ 24 hours
 Pineal gland regulation –
  releases melatonin
 Suprachiasmatic Nucleus
  (SCN) acts as a biological clock
     Found in the hypothalamus
     Just above the optic chiasm
     Receives info from the retina
 Retinohypothalamic pathway
 GABA released from the
  hypothalamus shuts down
  arousal systems
RETICULAR ACTIVATING SYSTEM
              RAS  is responsible for
               sleep/wake behavior and
               arousal
              Sensory systems  RAS
                Cortex
              Cortex can stimulate RAS
               suggesting wakefulness
               can be consciously
               maintained
ANATOMY OF DREAMING
 During   REM Sleep
     ACTIVE                        INACTIVE
       Reticular formation
                                      Parietal Cortex
       Thalamus
                                      Prefrontal Cortex
       Hypothalamus

       Amygdala & Hippocampus

       Visual Cortex
SLEEP IN ANIMALS
  Sleep is risky!
  Why is sleep important?

  Adaptation
      Energy conservation
      Predator vs. prey
WHAT DOES SLEEP DO FOR US?
 Restoration
            and repair, maintaining
 homeostasis
     Sleep deprivation studies show poor cognition and
      physiological consequences
 MEMORY!!!
     Activation during REM sleep
Sleep anatomy etc.

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Sleep anatomy etc.

  • 2. BIOLOGICAL CLOCKS  Circadian rhythms – daily cycles of ~ 24 hours  Pineal gland regulation – releases melatonin  Suprachiasmatic Nucleus (SCN) acts as a biological clock  Found in the hypothalamus  Just above the optic chiasm  Receives info from the retina  Retinohypothalamic pathway  GABA released from the hypothalamus shuts down arousal systems
  • 3. RETICULAR ACTIVATING SYSTEM  RAS is responsible for sleep/wake behavior and arousal  Sensory systems  RAS  Cortex  Cortex can stimulate RAS suggesting wakefulness can be consciously maintained
  • 4. ANATOMY OF DREAMING  During REM Sleep  ACTIVE  INACTIVE  Reticular formation  Parietal Cortex  Thalamus  Prefrontal Cortex  Hypothalamus  Amygdala & Hippocampus  Visual Cortex
  • 5. SLEEP IN ANIMALS  Sleep is risky!  Why is sleep important?  Adaptation  Energy conservation  Predator vs. prey
  • 6. WHAT DOES SLEEP DO FOR US?  Restoration and repair, maintaining homeostasis  Sleep deprivation studies show poor cognition and physiological consequences  MEMORY!!!  Activation during REM sleep