More Related Content Similar to Antibiotics Etiology & Treatment Of Bacterial Infections In Children (20) More from Dang Thanh Tuan (20) Antibiotics Etiology & Treatment Of Bacterial Infections In Children19. Categories of S. pneumoniae Susceptible to penicillin ........... ≤ 0.06 ug/ml Intermediate to penicillin ........... 0.1-1.0 ug/ml Resistant to penicillin ............ ≥ 2.0 ug/ml 22. Bacteriologic Failure Rates in Acute Otitis Media Antibiotic Haemophilus Pneumococcus Amoxicillin 28% 5% Augmentin 22% 6% Cefaclor 38% 18% Cefuroxime 15% 8% Cefprozil 53% 8% Cefixime 3% 32% Azithromycin 80% 6% Placebo 25-50% 75-85% 23. Recommended Antibiotic Therapy of Acute Otitis Media First Line Amoxicillin (80-90 mg/kg/day; Q 8-12 hours) Second Line Augmentin (80-90 mg/kg/day; Q 8-12 hours) Cefuroxime (30 mg/kg/day; Q 12 hours) CDC Working Group on DRSP-AOM, 1998 24. Individualizing Therapy of Acute Otitis Media 5 days of therapy Older child Summer months Otitis-free (or poor) past Mild episode Prompt improvement 10 days of therapy Younger child Winter months Otitis-rich past Severe episode Slow improvement 25. The diagnosis of acute bacterial sinusitis should be based on clinical criteria in children who present with upper respiratory symptoms that are either persistent or severe. 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