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IBD

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Crystal Byerly
Crystal Byerly
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Inflammatory Bowel Disease Crystal M. Byerly, PA-C Seton Hill University PA Program Grant from Centocor, Inc.
Learning Objectives ,[object Object],[object Object],[object Object],[object Object]
Inflammatory Bowel Disease ,[object Object],[object Object]
IBD = Crohn’s Disease and Ulcerative Colitis ,[object Object],[object Object]
[object Object],[object Object]
Ulcerative Colitis
Disease Process of Ulcerative Colitis ,[object Object],[object Object],Artwork is reproduced, with permission, from www.medicinenet.inc all rights reserved. 2007
Ulcerative Colitis ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Ulcerative Colitis ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Ulcerative Colitis ,[object Object],[object Object],[object Object]
Classifications of UC Severity ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Complications of Severe UC ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Crohn’s Disease
Crohn’s Three Main Patterns of Distribution ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Crohn’s Disease ,[object Object],[object Object],[object Object]
Crohn’s Disease Symptoms ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Crohn’s Disease ,[object Object],[object Object],[object Object],[object Object]
Crohn’s Complications ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Extraintestinal manifestations of IBD ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object]
Genetics of IBD ,[object Object],[object Object],[object Object],[object Object],[object Object]
ColoRectal Cancer and IBD ,[object Object],[object Object],[object Object],[object Object],[object Object]
Diagnosing IBD
Differential Diagnosis of IBD ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Current Diagnostic Tools for Initial IBD Diagnosis ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
There is no ONE single test to dx IBD. ,[object Object],[object Object],[object Object],[object Object]
Common Bloodwork in diagnosing IBD ,[object Object],[object Object],[object Object],[object Object],[object Object]
Differentiating type of IBD Sandborn WJ et al, Inflamm Bowel Dis 2001;7:192-201 Peeters M et al, AM J Gastroenterology 2001; 96:730-4 LAB TEST SENSITIVITY SPECIFICITY TYPE IBD + pANCA 50-65% 85-92% UC +ASCA 55-61% 88-95% CROHN’S +pANCA & ASCA - 44-57% 81-97% UC -pANCA & ASCA+ 38-56% 94-97% CROHN’S
Immune Markers being studied for diagnosing IBD ,[object Object],[object Object],[object Object],[object Object],[object Object]
IBD Management ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Acute Management of IBD ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Chronic Therapy of IBD ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Corticosteroids ,[object Object],[object Object],[object Object],[object Object],[object Object]
Cyclosporine ,[object Object],[object Object],[object Object],[object Object]
Mesalamines: 5-ASA/Aminosalicylates ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Mesalamines continued ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Thiopurines ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Methotrexate ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Biologic Therapy –vs- Conventional Therapy in IBD ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Biologic Therapy with CD ,[object Object]
Biologic Therapy ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Adalimumab ,[object Object],[object Object],[object Object]
Combination Therapy for Crohn’s ,[object Object],[object Object],[object Object],[object Object],[object Object]
Biologic therapy with UC ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
IBD Surgery Treatment
Crohn’s Surgery ,[object Object],[object Object],[object Object],[object Object]
Surgical Therapies with Fistula ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Ileal Resection in Crohn’s Disease ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object]
Post-Op Recurrence of CD ,[object Object],[object Object],[object Object],[object Object]
Ulcerative Colitis Surgery Indications ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Surgery types with UC ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object]
[object Object],[object Object]
Conclusion Review of Learning Objectives ,[object Object],[object Object],[object Object],[object Object]
Thank You

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IBD

  • 1. Inflammatory Bowel Disease Crystal M. Byerly, PA-C Seton Hill University PA Program Grant from Centocor, Inc.
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  • 28. Differentiating type of IBD Sandborn WJ et al, Inflamm Bowel Dis 2001;7:192-201 Peeters M et al, AM J Gastroenterology 2001; 96:730-4 LAB TEST SENSITIVITY SPECIFICITY TYPE IBD + pANCA 50-65% 85-92% UC +ASCA 55-61% 88-95% CROHN’S +pANCA & ASCA - 44-57% 81-97% UC -pANCA & ASCA+ 38-56% 94-97% CROHN’S
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