1. It’s your L ife! Pharmacy Event 2007

2. FoodState ® Nutrients Highly Concentrated Natural Whole Food Flavonoids Lipids Vitamins SOD Protein Carbohydrates Dietary Fibre Minerals Intrinsic Enzymes Glutathione Β -glucan

3. Various Nutrients

10. FoodState Technology Process for Yeast & Yoghurt Receptor sites specially activated by a specific enzyme to potentiate receptor site availability

11. FoodState Technology Nutrient complexed with carrier peptide to take to activated receptor sites

12. FoodState Technology End result : Citrus concentrate loaded with high level Vit C without the food bulk

13. FoodState Technology Vegetable enzymes used to deactivate host matrix growth

14. Inhibition of LDL+VLDL oxidation Different forms of selenium & ascorbic acid

15. Toxicity FoodState ® & Isolated USP Minerals Selenium in Biology & Medicine. Combs et al

16. FoodState ® & Isolated USP %Bioavailability in serum Royal Society of Chemistry, Southgate et al

17. FoodState ® & Isolated USP % Bioavailability in liver Royal Society of Chemistry, Southgate et al

18. Comparative Bioavailability FoodState ® Minerals & Isolated USP %Relative Bioavailability In Serum Royal Society of Chemistry, Southgate et al

19. Inhibition of in vitro cupric ion-induced LDL + VLDL (Concentration required to inhibit oxidation by 50%) Journal of Medicinal Food. Vinson et al

20. Effect Of FoodState ® Vitamin C Plasma Cholesterol - LDL+VLDL - Triglyceride (After One Month) Journal of Agricultural & Food Chemistry. Vinson et al

21. Blood coagulation & Fribrinolysis. Loots et al tPA Tissue Plasminogen activator The Haemostatic System (tPA: Tissue Plasminogen activator; PAI-1: plasminogen inhibitor 1) Endothelium Coagulation Fibrinolysis Thrombin Anti-thrombin Fibrinogen Fibrin Plasminogen Plasmin PAI-1 Plasminogen Activator Inhibitor 1 A2-antiplasmin D-dimer Platelets TAT – thrombin-antithrombin complex Marker of activation of coagulation PAP – plasmin-antiplasmin complex Marker of fibrinolyctic activity Inactivation clot thin clot

22. The effects of FoodState ® Vitamin C Complex on Haemostasis Potchefstroom University of Christian Higher Education 2001 “ Resulted in a new steady state of haemostatic balance that may be protective of CVD” “ When compared to the placebo group these decreases were significant” Thrombin Clotting Plasmin Thinning

23. Comparison of intestinal calcium absorption from a yeast derived calcium preparation and calcium carbonate Pettifor JM 1 , Abrams SA 2 , Pringle A 3 , Norris SA 1 , Arvanaghi M 4 1 MRC Mineral Metabolism Research Unit, University of the Witwatersrand 2 Children’s Nutrition Research Center, Baylor College of Medicine, Texas 3 Sportron International Pty, Ltd, Johannesburg 4 Grow Co Inc, USA

25. Calcium absorption

26. In medicine think common things first Horses! Not uncommon things first Zebras!

27. Not zebras Red flags ALMOST ZERO ZEBRAS Red flags

29. H - Headaches E - Energy A - Anxiety/stress R - Reeling H - Hormones O - Overweight O - Oedema F - Fears B - Bloating E - Esteem A - Anger T - Tired S - Sadness T - Tummy H - Hyper/hypotension I - Immune N - Neck & Back pain K - Kidney / Bladder H - Hyperactive O - Obsessiveness R - Remembering S - Sinus E - Engram S - Sleep

30. THREE HORSES Stress Energy Immune

31. Causes: Body: Lack of sleep Reliant on stimulants Exercise Injuries Birth Pregnancy Mind: Lifestyle Habits Addiction Economics Obsessions Spirit: Death Divorce Isolation Insecurity Stress

32. Cortisol – high and prolonged in blood stream Body: Thyroid Blood Sugar Bone Density Muscle Spasm Immune Inflammation Blood Pressure Abdominal fat – heart attacks, strokes Mind: Cognition Spirit: Adrenal exhaustion=“burn out” Chronic Stress

33. Body Headaches Spinal, shoulder pain Blood pressure Sleep disturbed Weight changes Fatigue Libido Mind Depression Mood swings Overwhelmed Concentration Decision difficulties Relationship conflicts Addictions Spirit Emptiness Loss of faith Withdrawal Suicidal Apathy FoodState ® Multi Vitamin & Mineral Formula Calcium & Magnesium Formula B-Complex Sugar Balance Formula B-Complex Lots of Libido Stress Symptoms

34. Beta carotene 7.5mg Vitamin D 2.5 μ g Vitamin E 5mg Vitamin C 30mg Vitamin B1 (thiamin) 0.7mg Vitamin B2 (riboflavin) 0.8mg Vitamin B3 (niacinamide) 9mg Vitamin B6 (pyridoxine) 1mg Folacin 100 μ g Vitamin B12 (cyanacobalamin) 0.5 μ g Biotin 7 μ g Pantothenic Acid 3mg A damage control , completely balanced Multi vitamin & mineral complex Anti-ageing, Anti-stress, Anti-fatigue, Immune-supporting, Performance-enhancing . FoodState ® Multi Vitamin & Mineral Formula 5 μ g Molybdenum 3mg Potassium 3mg Magnesium 25 μ g Calcium 2.5mg PABA 2.5mg Inositol 0.5mg Boron 25 μ g GTF Chromium 50 μ g Selenium 0.25mg Manganese 0.26mg Copper 75 μ g Iodine 2.5mg Zinc 2.5mg Iron

35. Body: 99% stored in bones & teeth about 1.2kg 1% Blood, muscles, extracellular fluids Muscle contraction Vasoconstriction & vasodilatation Sweating head (cell membrane permeability) Mind: Sensitive to criticism, being observed, insecure, withdrawn. Spirit: Not safe FoodState Calcium

36. Body: Reduces histamine Synthesis hyaluronic acid (Cushioning, lubricating component of connective tissues) TMJ Mitral valve prolapse, 10% - wired or tired, --- joint hypermobility) Menstrual cramps Fibromyalgia Muscles like corduroy Mind: Anxiety ,16 times more likely joint hypermobility Reduces adrenaline Depression Migraines – intravenous 80% Spirit: Better Rhythm FoodState Magnesium

37. Magnesium Headaches / Migraines < Noise < Noise < Bright lights < Bright Lights Headaches Headaches Mitral Valve Prolapse Mitral Valve Prolapse Anxiety Anxiety Menstrual Cramps Menstrual Cramps Nausea Nausea FoodState ® Magnesium Complex Magnesium

38. FoodState ® Calcium & Magnesium Formula Calcium & Magnesium Complex

40. Body: Water soluble – “Spark Plug” More sugar more B Tingling extremities Aching, sore Heart rhythms Ecology – bowel flora produces B Mouth, tongue symptoms Skin – rashes, dermatitis Homocysteine - cardio/stroke, folic acid, B12, B6 Mind: Anxiety Sleep Spirit: Burnout Weight loss Weight changes Fatigue Foodstate Vitamin B complex

41. Mind Depression Mood swings Overwhelmed Concentration Decision difficulties Relationship conflicts Addictions FoodState ® Optimism & Joy FoodState ® Iron & Molybdenum Complex Stress

42. Tryptophan Methionine Tyrosine Glycine Serine Taurine Carnitine Aspartic acid Glutathione Glutamine Glutamic acid Asparagine Dopamine Noradrenalin Adrenalin Pyroglutamate Serotonin Tryptamine Melatonin Thyroxine GABA Methionine Phenylalanine Threonine Valine Leucine lysine Cysteine Essential amino acid Amino acid Neurotransmitter Family Tree of Key Neurotransmitters

43. L-TRYPTOPHAN – turkey, fish, meat, peanuts, sesame high carbs aid serotonin brain absorption--sleepy Folic acid Vit. C B3 B6 Iron 5HTP Biotin Zinc B3 SEROTONIN B5-(pantothenic acid) Serotonin Pathway

44. Restless Over Reaction – “Twitchers” Light Noise, Balance TMJ, Clenching Craving Carbs Anorexia, Temperature Tingling, Burning < Exertion B6 Slowness Swelling Stretch Marks PMS Global Symptoms that Precede Poor Serotonin Synthesis

45. FoodState ® Optimism & Joy Folic acid – mood changes, blue under eyes, restless legs, lips pale cracked Vit. C – fragile skin, gums, teeth. little subcutaneous spots B1 - < noise, exercise, balance. Craving carbs,hands / feet cold numb, tingling B3 - < exercise, burning, tender feet & hands, TMJ, Schizophrenia B6 – slow, swell, stretch marks, PMS Biotin – Dry, itch, tingling skin, hair Zinc – spotty/greasy skin, spotty/brittle nails, craving carbs, anorexia, smell / taste B5 - < exercise, burning, tender, feet hands, TMJ, twitches B12 – behaviour (elderly), intrinsic factor, blue under eyes, balance, thermally sensitive, mouth, skin / lips pale, white / yellow spots Magnesium - < noise, twitches, muscle weak / spasm St. John’s Wort – inhibits uptake, modulates serotonin, dopamine, noreadrenalin Trimethyl Glycine – remethylates homocysteine to methionine (increase SAMe) Rhodiola Rosea – concentration, memory, adaptogen L-Tyrosine – precursor catecholamine, pain L-Glutamine – precursor to GABA, blood brain barrier Panax Ginseng - cortisol

46. Source: DeMaeyer, EM, Dallman P, Gurney JM, Hallberg L, Sood SK, & Srikantia SG (1989). Preventing and controlling iron deficiency Anaemia through primary health care: a guide for health administrators and programme managers, pp 5-58 WHO Geneva 50% 50% 55% 60% 25% Proportion of People in developing countries who are Anaemic

47. Body: Anaemia Smooth tongue Fatigue Spoon shaped brittle nails Shortness of Breath Cold Extremities Rapid Fluttering Heartbeat Craving ice, dirt, clay (pica) Corners of mouth crack Reduced T & B cells Hypochlorrhydria, Helicobacter pylori Mind : Irritable, compulsive Spirit : Iron Lady FoodState ® Iron & Molybdenum

48. FoodState ® Iron & Molybdenum FoodState ® Enthusiasm & Energy Spirit Emptiness Loss of Faith Withdrawal Suicidal Apathy Stress

49. Noradrenaline - Alertness and Arousal L-PHENYLALANINE- turkey, eggs, milk, meat phenylketonuria - aspartame, blonde, fair, mousy odour Folic acid, magnesium, iron, zinc, copper, C L-TYROSINE Folic acid L-DOPA (Parkinson's) B6, zinc DOPAMINE –motor arousal vit. C Noradrenaline – elation, euphoria, focused attention Methylation Adrenaline – fright,flight,fight,freeze 4 to 1 noradrenaline cortisol Sympathetic Nervous System Compounds

50. FoodState ® Enthusiasm & Energy L-Tyrosine – precursor; dopamine, pain Zinc – Spotty / greasy skin, spotty brittle nails, craving carbs, anorexia, smell, taste Vit. C – Fragile skin / gums, teeth, little subcutaneous spots B6 - Slow, Swell, Stretch marks, PMS Lipophos – Phosphorylated Lipoprotein – intermediate building blocks for ATP Rhodiola Rosea – Focus, Memory, learning, Adaptogen Arginine Pyroglutamate - Memory, Alertness left & Right hemispheres Citrus Aurantium – CNS stimulating Ginseng - Adaptogen

51. Remember FoodState ® Iron & Molybdenum

52. Second horse Energy

53. PROTEIN FAT B6 pyridoxine B12 cyanocobalamin Folic acid B1 thiamine, B2 riboflavin Magnesium Manganese Glycerol B1 thiamine B2 riboflavin Biotin Magnesium If insufficient oxygen (anaerobic) = lactic acid B5 pantothenic acid Acetyl-coenzyme A (controls flow of oxygen & free radicals) Fatty Acids 90% of energy Co-enzyme Q10 (1-10)Controls f low of oxygen & free radicals B2, B3, niacin, iron CoQ copper sulphate ( + oxygen) urine CO2 Carbon dioxide exhale H2O water Energy SUGAR PYRUVIC ACID Acetyl CoA KREB CYCLE B1, B2, B3, C, Magnesium HYDROGEN FoodState B-complex FoodState Essential Fatty Acids FoodState Iron & Copper FoodState Magnesium FoodState Anti-Ageing Formula Energy How the mitochondria (DNA from mother) turns food into energy

54. The vicious cycle Energy

56. Third Horse Immune

57. Bone Marrow Special Defense General Defense Lymphocytes Macrophage - Big eaters -WBC Granulocyte – Granulated WBC Monocytes Leukocyte – immune WBC Compliment factors Helper cells Leukocyte WBC Killer cells T lymphocyte T-lymphocytes Helper cells WBC Suppressor cells Immune T cells Plasma Cel l immune CD4 B lymphocytes Antibodies against antigens Plasma cell Bacteria virus Fungus Antibodies Feeding Cells Intestinal tissue Liver etc. Thymus Compliment System Immune

58. The immune system is extremely sensitive to oxidative damage. Deficiencies in vital antioxidants like: A,C,E, Selenium and Zinc impairs our Immune system Betacarotene 5mg Vit C 50mg B12 2.5 μ g Zinc 2.5mg Selenium 150µg Bioflavonoids 80mg Glutathione complex 50mg Cysteine 50mg Glutamine 250mg Betasitosterol 60mg FoodState ® Immune Formula Immune

60. The Real Key FoodState ® Vitamin C is 12 times more bioavailable than Ascorbic Acid University of Scranton Retention – About 8 hours Bioavailability- USP 100 Retention- About 24 hours Bioavailabilty- 1210 FoodState ® C Complex Bioavailability

62. Zinc atoms surround a group of T cells. Zinc deficiency has been linked with impaired immune function and lowered resistance to infection. Godfrey JC, Sloane BC, Smith DS, et al. Zinc gluconate and the common cold: a controlled clinical study. J Intern Med Res . 1992;20:234-246. Zinc FoodState ® Zinc & Copper Complex Immune

63. Body: Immune Allergy Inflammation Autoimmune Lowers high blood cholesterol and triglyceride levels Dilating or constricting blood vessels Blood sugar Skin, nails, hair R egulating smooth muscle and autonomic reflexes Mind: Concentration , Memory, Mood swings (PMS) Spirit : Depression FoodState ® Essential Fatty Acid Complex Immune FLAXSEED OIL 1000mg Alpha Linolenic (Omega 3) 57% Linoleic (Omega 6) 16% Oleic (Omega 9) 18% Palmitic stearic & other 9%