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A presentation at the Bioinformatics Open Source Conference 2011
G-language Project                                    Keio University    Cornell University




         Genome Analysis Environment (GAE) Arakawa et al. (2003) Bioinformatics
         “EMBOSS in Perl” - collection of 100s of programs, API for I/O, graphing, statistics
          Perl Shell, BioPerl compatible

         Genome Projector Arakawa et al. (2009) BMC Bioinformatics
         Genome browser using Google Maps API

          Pathway Projector    Kono et al. (2009) PLoS One
         Pathway browser / mapping tool using Google Maps API

         Bookmarklet
         Intuitive query tool for EMBOSS, GAE services ( >500)
         Databases (NCBI Entrez, KEGG, EB-eye, Bio2RDF)

REST/SOAP     REST/SOAP web service for GAE Arakawa et al. (2010) NAR

              Keio Bioinformatics Web Services Oshita et al. (2011) SCFBM
  KBWS
              EMBASSY package for 50 web service tools
G-language Project: the last 10 years

                                                                  Bioinformatics                                                                      JPS                                    GGG                                        NAR WS issue
                           ISMB Best                              original paper                                                                    review                                  review                                       WS paper
                          Poster Award

                                                                      RCES                                        GEM System
                                                                 Bioinformatics                                 BMC Bioinformatics                                                              Open-Bio.jp
                                                                                                                                                                                                   book
                                                           CBI Conference                                                                                                                                                 Pathway
                                                                                              marraydb cDNA          GPAC                  MEGU Restauro-G                          Mashup Awards 4th Genome
                 SFC Award                                Best Poster Award                     ISB     GPB           ISB                   ISB    GPB
                                                                                                                                                                                                                     CGR Projector Mashup Awards 6th KBWS
                                                                                                                                                                                    Genome Projector Projector      SCFBM PLoS One G-language Bookmarklet SCFBM
                                Keio Presidential Award                                                                                                                                                   BMC
                                                                                                                                                                                                     Bioinformatics

2001

  2001             2002                    2003                      2004                         2005                      2006                         2007                      2008                  2009                    2010
         v.0.x    v.1.0.x       v.1.1.x             v.1.2.x                   v.1.3.x                    v.1.4~5.x                               v.1.6.x                v.1.7.x                               v.1.8.x
                                 G-language Shell
                                      Inspire                                                   v.1.49 release
                                                                                                  Windows
                                                                                             support discontinued
                                                                                                                                         v.1.6 release
                                                                                                                                           MacOS X
                                                                                                                                                                  v.1.7 release
                                                                                                                                                                Bluebird/Infinity
                                                                                                                                                                                                                                                 2011
                                                                                                                              KNOB                                                        CGR             REST/SOAP                       KBWS
                                                  GPAC                                               cDNA

                                                                                                                                                                                                                                        Restauro 2
                      v.1.1 released                                                                                        Restauro-G
                       Skyline core
                   BioPerl compatibility                                                                                                                                                                            g2s                   Moco
                                                                        GEM System                                          E-Cell 3D
                                                                                                                                                                          v.1.8 release
                     v.1.0.0 asimo release                                                                                                                      Shell + Web Service enhancements
                     GUI (Linux/Windows)                                                                                     SplitsX


                                                                                 marraydb                                    MEGU


                                             Dynamic Loader                                 ism                      Genome Projector
                                             plug-in function                                                                                                             Pathway Projector
                    Prelude core                                                                                                                                                                                        G-language Bookmarklet
                  Odyssay Package
                  g-language.org                  RCES
Statistics




       also distributed at bioinformatics.org, CPAN, KNOB, CD-ROM
Lessons leant...
updates!
Genome Projector
Zoomable Genome Browser with Multiple Views
                           powered by Google Maps API

    Mash up Awards 4 - Google Award
                Arakawa et al. (2009) BMC Bioinformatics
G-language Bookmarklet: The Gateway to Semantic Web.
             http://www.g-language.org/wiki/bookmarklet

   EMBOSS

    KBWS                                    Wikipedia

  G-language                                  Eijiro

                                             Google
   Bio2RDF
                                             PubMed
    EB-eye

               KEGG/LinkDB     Entrez         BLAST
and beyond...
Bosc2011 arakawa

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Bosc2011 arakawa

  • 1. A presentation at the Bioinformatics Open Source Conference 2011
  • 2.
  • 3. G-language Project Keio University Cornell University Genome Analysis Environment (GAE) Arakawa et al. (2003) Bioinformatics “EMBOSS in Perl” - collection of 100s of programs, API for I/O, graphing, statistics Perl Shell, BioPerl compatible Genome Projector Arakawa et al. (2009) BMC Bioinformatics Genome browser using Google Maps API Pathway Projector Kono et al. (2009) PLoS One Pathway browser / mapping tool using Google Maps API Bookmarklet Intuitive query tool for EMBOSS, GAE services ( >500) Databases (NCBI Entrez, KEGG, EB-eye, Bio2RDF) REST/SOAP REST/SOAP web service for GAE Arakawa et al. (2010) NAR Keio Bioinformatics Web Services Oshita et al. (2011) SCFBM KBWS EMBASSY package for 50 web service tools
  • 4.
  • 5. G-language Project: the last 10 years Bioinformatics JPS GGG NAR WS issue ISMB Best original paper review review WS paper Poster Award RCES GEM System Bioinformatics BMC Bioinformatics Open-Bio.jp book CBI Conference Pathway marraydb cDNA GPAC MEGU Restauro-G Mashup Awards 4th Genome SFC Award Best Poster Award ISB GPB ISB ISB GPB CGR Projector Mashup Awards 6th KBWS Genome Projector Projector SCFBM PLoS One G-language Bookmarklet SCFBM Keio Presidential Award BMC Bioinformatics 2001 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 v.0.x v.1.0.x v.1.1.x v.1.2.x v.1.3.x v.1.4~5.x v.1.6.x v.1.7.x v.1.8.x G-language Shell Inspire v.1.49 release Windows support discontinued v.1.6 release MacOS X v.1.7 release Bluebird/Infinity 2011 KNOB CGR REST/SOAP KBWS GPAC cDNA Restauro 2 v.1.1 released Restauro-G Skyline core BioPerl compatibility g2s Moco GEM System E-Cell 3D v.1.8 release v.1.0.0 asimo release Shell + Web Service enhancements GUI (Linux/Windows) SplitsX marraydb MEGU Dynamic Loader ism Genome Projector plug-in function Pathway Projector Prelude core G-language Bookmarklet Odyssay Package g-language.org RCES
  • 6. Statistics also distributed at bioinformatics.org, CPAN, KNOB, CD-ROM
  • 9. Genome Projector Zoomable Genome Browser with Multiple Views powered by Google Maps API Mash up Awards 4 - Google Award Arakawa et al. (2009) BMC Bioinformatics
  • 10.
  • 11.
  • 12. G-language Bookmarklet: The Gateway to Semantic Web. http://www.g-language.org/wiki/bookmarklet EMBOSS KBWS Wikipedia G-language Eijiro Google Bio2RDF PubMed EB-eye KEGG/LinkDB Entrez BLAST
  • 13.
  • 14.