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VTT 235/245 Ana tomy &
P a thology La b for Ve te rina ry
          Te chnicia ns

        Ca rdiova s cula r S ys te m
          I. Ca rdia c S ys te m
        II. Circula tory S ys te m
Ca rdia c S ys te m

The ma jor function of the CVS is
 tra ns porta tion, with blood be ing the
 tra ns port ve hicle .
Circula tory P a ths -
  Systemic Circulation- is blood flow to a nd
   from mos t pa rts of the body.
  Pulmonary Circulation- is blood flow to
   a nd from the lungs , during which it picks
   up oxyge n a nd re turns it to the he a rt.
Ca rdia c S ys te m
Circula tory P a ths -
   Coronary Circulation- blood flow to the he a rt
    mus cle its e lf.
   Portal Circulation- a ve nous s ys te m in which
    blood re turns from the inte s tine s a nd proce e ds to
    the live r be fore re turning to the he a rt.
   * * Venous System- re turns blood to the he a rt.
   Arterial System- ca rrie s blood a wa y from the
    he a rt.
He a rt

A mus cula r, four cha mbe re d orga n tha t
 drive s the circula tory s ys te m.
Lie s in the mediastinum.
Base- top of the he a rt.
Apex- bottom of the he a rt.
He a rt…
The oute r la ye r of the he a rt is ca lle d the
 pericardium.
The pe rica rdium cons is ts of 2 la ye rs :
   An oute r fibrous pericardium- ma de of tough,
    fibrous CT tha t prote cts the he a rt a nd loos e ly
    a tta che s it to the dia phra gm.
   An inne r serous pericardium- which is a ls o ma de
    of 2 la ye rs :
      Inner Visceral layer(epicardium)
      Outer parietal layer
He a rt…

Ins ide the s a c forme d by the
 pe rica rdium is the thicke s t la ye r of
 he a rt tis s ue , the myocardium.
Be twe e n the cha mbe rs a nd the
 myoca rdium is a thin me mbra nous
 lining ca lle d the endocardium.
He a rt…
Compartments- the he a rt ha s 4 cha mbe rs .
  The 2 a tria re ce ive blood a nd pump it down into
   the re s pe ctive ve ntricle s , which pump it a wa y
   from the he a rt.
Right Atrium- compa rtme nt re ce iving
 de oxyge na te d blood.
  Interatrial septum- the wa ll s e pa ra ting the a tria .
  Fossa Ovale- a re mna nt of the fe ta l fora me n
   ova le .
He a rt…

Right Ventricle- compa rtme nt
 re ce iving blood from the right a trium.
  The right ve ntricula r wa ll is thinne r
   be ca us e le s s pre s s ure is re quire d to
   move blood through the lungs tha n
   through the body.
  Ventricular septum- s e pa ra te s the
   ve ntricle s .
He a rt…
Left Atrium- the compa rtme nt
 re ce iving oxyge na te d blood from the
 lungs via the pulmona ry ve ins .
Left Ventricle- compa rtme nt re ce iving
 oxyge na te d blood from the le ft a trium
 a nd s e nding it out the a orta to the body
 (s ys te mic circula tion).
  The le ft ve ntricula r wa ll is thicke r be ca us e
   of the highe r pre s s ure re quire d for
   s ys te mic circula tion.
He a rt…

Ve ntricula r S tructure s -
  Papillary Muscles- mus cula r proje ctions
   s e rving a s a tta chme nts for the chorda e
   te ndine a e of the AV va lve s .
  Chordae Tendineae- tough s tra nds
   a nchoring the fre e e dge s of the AV va lve s
   to the pa pilla ry mus cle s .
He a rt…

Va lve s -
  AV Va lve s - pre ve nt ba ckflow into the a tria
   during ve ntricula r (s ys tole ) contra ctions .
     Right AV (tricus pid) va lve
     Le ft AV (bicus pid/mitra l) va lve
     “Tri” before you “bi” !!!
  S e mi-luna r va lve s -
     Aortic
     P ulmona ry
Ma jor Ve s s e ls

Cranial Vena Cava- the la rge ve in
 re turning blood from the he a d, ne ck,
 a nd thora cic limbs to the right a trium.
Caudal Vena Cava- la rge ve in re turning
 blood from pa rt of the thora x, vis ce ra ,
 a nd the ca uda l pa rt of the body to the
 right a trium.
Ma jor Ve s s e ls …

Pulmonary Trunk- the la rge ve s s e l
 ca rrying blood from the right ve ntricle
 to the pulmona ry a rte rie s , a nd thus , to
 the lungs .
Pulmonary Arteries- the two bra nche s
 of the pulmona ry trunk ca rrying blood
 to the right a nd le ft lung lobe s .
Ma jor Ve s s e ls …

Pulmonary Veins- the nume rous
 ve s s e ls e mptying oxyge na te d blood
 into the le ft a trium.
Aorta- ma jor outflow from the le ft
 ve ntricle into the s ys te mic circula tion.
Ca rdia c Cycle
Both a tria contra ct a t virtua lly the
 s a me time .
Blood e nte rs the a tria while the y a re
 re la xe d.
The atrioventricular (AV) valves a re
 ope n s o blood flows ra pidly through the
 ve ntricle s .
Approxima te ly 70% of ve ntricle filling
 occurs during this pha s e .
Ca rdia c Cycle …

The a tria the n contra ct, which is ca lle d
 a tria l s ys tole , a nd the ve ntricle s fill
 comple te ly.
Ne xt, both ve ntricle s contra ct a nd the
 AV va lve s a re force d to clos e ,
 producing the firs t a udible he a rt s ound.
P re s s ure on the ve ntricle s ca us e the
 s e mi-luna r va lve s to ope n a nd blood is
 e je cte d into the pulmona ry a rte ry a nd
 a orta .
Ca rdia c Cycle …

This contra ction is ca lle d ventricular
 systole.
The s e mi-luna r va lve s clos e producing
 the s e cond he a rt s ound.
The cycle is re pe a te d with the pe riod
 of re la xa tion ca lle d diastole.
How Blood P umps Through the
              He a rt
 The Right Atrium, re ce ive s “de oxyge na te d blood" from the body.
  Blood will be pus he d through the tricus pid va lve to the
 Right Ve ntricle , the cha mbe r which will pump to the lungs through the
  pulmonic va lve to the
 P ulmona ry Arte rie s , providing blood to both lungs . Blood is circula te d
  through the lungs whe re ca rbon dioxide is re move d a nd oxyge n
  a dde d. It re turns through the
 P ulmona ry Ve ins , which e mpty into the
 Le ft Atrium, (oxyge na te d blood) a cha mbe r which will pus h the Mitra l
  Va lve ope n. Blood the n pa s s e s into the
 Le ft Ve ntricle . Although it doe s n't a lwa ys look like it in dra wings done
  from this a ngle , this is the la rge s t a nd mos t importa nt cha mbe r in the
  he a rt. It pumps to the re s t of the body. As it pumps , the pre s s ure will
  clos e the mitra l va lve a nd ope n the a ortic va lve , with blood pa s s ing
  through to the
 Aorta , whe re it will be de live re d to the re s t of the body.
He a rt Ra te & Ca rdia c Output

Cardiac output- the a mount of blood
 tha t le a ve s the he a rt.
De te rmine d by:
  Stroke Volume- the a mount of blood
   e je cte d with e a ch ca rdia c contra ction.
  Heart Rate- how ofte n the he a rt
   contra cts .
Conduction S ys te m

Ea ch comple te contra ction a nd
 re la xa tion is ca lle d a cardiac cycle.
Two ma in pa rts -
  Systole- whe n the he a rt mus cle contra cts
   a nd blood is e je cte d from the a tria to the
   ve ntricle s a nd out the a orta .
  Diastole- the he a rt re la xe s a nd re fills with
   blood.
Conduction S ys te m…
The impuls e come s
 from the SA node.
  A s pe cia lize d a re a
   of ca rdia c mus cle
   ce lls tha t pos s e s the
   a bility of
   a utoma tica lly
   ge ne ra ting the
   e le ctrica l impuls e s
   tha t trigge r the
   re pe a te d be a ting of
   the he a rt.
Conduction S ys te m…
The S A node
 ge ne ra te s a n
 e le ctrica l curre nt by
 the move me nt of
 ca tions a cros s the
 oute r me mbra ne s of
 it’s ce lls .
Conduction S ys te m…
This proce s s ca lle d depolarization,
 ge ne ra te s a n e le ctrica l curre nt which ca us e s
 the he a rt mus cle to contra ct.
Ca rdia c mus cle ca n tra ns mit a n impuls e
 from one ce ll to a nothe r, s o e le ctrica l
 impuls e s a nd contra ctions s pre a d a cros s the
 he a rt like a wa ve .
Afte r the impuls e is ge ne ra te d in the S A
 node , it s pre a ds in a wa ve a cros s both a tria ,
 ca us ing the to contra ct a nd pus h blood
 through the AV va lve s into the ve ntricle s ,
 which a re s till re la xe d.
Conduction S ys te m…
The impuls e tra ve ls to the AV node whe re it
 e ncounte rs a s light de la y.
   This is the only conduction route from the a tria to
    the ve ntricle s .
   The de la y pe rmits the a tria to comple te the ir
    s ys tolic contra ction be fore ve ntricula r s ys tole
    be gins .
Afte r the AV node , it tra ve ls to the
 s pe cia lize d fibe rs in the ve ntricle s ca lle d the
 bundle of His & the Purkinje fibers.
P a thology
He a rt Fa ilure
Whe n blood re turning to the he a rt ca nnot be
 pumpe d out a t a ra te ma tching the body’s
 ne e ds .
Ma ny ca us e s e xis t.
Mus t de te rmine if the fa ilure is a re s ult of
 myoca rdia l dys function (pump fa ilure ) or
 circula tory fa ilure (la ck of circula ting fluid
 volume .
Conge s tive He a rt Fa ilure - whe n the fa iling
 he a rt a llows fluid conge s tion a nd e de ma to
 a ccumula te in the body.
Congestive Heart Failure


A de ge ne ra tive dis e a s e whe re the va lve
 le a fle ts be come knobby a nd thicke ne d.
 Re gurgita ting blood ca us e s e nla rge me nt of
 the le ft a trium a nd le ft ve ntricle
Mitra l re gurgita tion mos t common ca us e ;
 30% of s ma ll bre e d dogs > 10 ye a rs old a re
 a ffe cte d
P re dis pos e d bre e ds include Ca va lie r King
 Cha rle s S pa nie ls , P oodle s , Mini S chna uze rs ,
 Chihua hua s , Cocke r S pa nie ls , Da chs hunds ,
 Bos ton Te rrie rs , & Fox Te rrie rs
P rogre s s ion of the dis e a s e ca n ta ke ye a rs
CHF (cont)



P re s e nt with ta chypne a , ha rs h lung
 s ounds , ins pira tory cra ckle s tha t
 progre s s to cra ckle s /whe e ze s
 throughout re s pira tion with a
 dis tinguis ha ble he a rt murmur
CHF a nima ls a re lite ra lly drowning in
 the ir own fluids .
P a te nt Ductus Arte rios is (P DA)-

 Mos t common
  conge nita l he a rt de fe ct
  of dogs
 The duct be twe e n the
  le ft pulmona ry a rte ry
  a nd the de s ce nding
  a orta in the fe tus doe s
  not clos e a t birth
 Re s ults in le ft s ide d
  CHF
 The re s ulting murmur is
  ofte n re fe rre d to a s a
  “ma chine ry murmur”.
Va lvula r S te nos is

                         A na rrowing of one
                          of the he a rt va lve s
                         Ma y be a ortic or
                          pulmonic
                         Ca us e s va rious
                          type s of murme rs
P e rs is te nt Right Aortic Arch

P RAA
The mos t common
 va s cula r ring
 a noma ly
Ca us e s a n
 obs truction of the
 e s opha gus
Re gurgita tion, a nd
 a s pira tion
 pne umonia a re
 s ome s igns in young
 we a ning a nima ls
P a te nt Ova le Fora me n

                      A.K.A. Inte ra tria l
                       S e pta l De fe ct
                      Fa ilure of the
                       ope ning be twe e n
                       the two fe ta l a tria to
                       clos e .
Chronic Mitra l Va lve Ins ufficie ncy
CMVI is the mos t commonly
 e ncounte re d a cquire d ca rdia c
 dis orde rs in the dog.
One of the mos t common ca us e s is
 chronic pe riodonta l dis e a s e .
  Ba cte ria living in ta rta r a re s howe re d into
   the bloods tre a m, colonizing on the va lve
   le a fle ts of the he a rt.
  The s tiff, ma lforme d le a fle ts fa il to clos e
   s ufficie ntly during s ys tole , re s ulting in
   re gurgita tion ba ck up into the a trium.
Ca nine Dila te d Ca rdiomyopa thy
One of the mos t common a cquire d
 ca rdiova s cula r dis e a s e s of dogs .
P rima rily a dis e a s e of olde r, ma le la rge &
 gia nt bre e d dogs .
The dis e a s e involve s the dila tion of a ll four
 cha mbe rs of the he a rt.
This dila tion (ca us e d by we a k, thin, & fla bby
 ca rdia c mus cle ) re s ults in:
   A de cre a s e in ca rdia c output.
   An incre a s e in ca rdia c a fte rloa d (blood le ft in the
    he a rt in dia s tole ).
DCM…

The e xa ct ca us e is unknown, a lthough
 vira l, nutritiona l, immune -me dia te d,
 a nd ge ne tic ca us e s ha ve be e n
 propos e d.
DCM re s ults in impa ire d s ys tolic
 function of the ve ntricle s a nd,
 the re fore , de cre a s e d s troke volume .
  The volume of blood e je cte d from the
   he a rt with e a ch contra ction.
DCM…

The e ffe ct on the a nima l is one of low-
 output circula tory fa ilure , e xhibite d by:
  We a kne s s
  Exe rcis e intole ra nce
  S yncope
  S hock
DCM…

Dogs with DCM fre que ntly e xpe rie nce
 the de ve lopme nt of a tria l fibrilla tion,
 which furthe r contribute s to a de cre a s e
 in ca rdia c output.
  S igns of a tria l fibrilla tion include ra pid,
   irre gula r he a rt rhythms or s udde n de a th.
Ca nine Hype rtrophic Ca rdiomyopa thy

An uncommon ca nine dis e a s e .
The le ft ve ntricula r mus cle a trophie s
 de cre a s ing the filling ca pa city of the
 ve ntricle a nd ofte n blocking the outflow
 of blood during s ys tole .
Fe line Dila te d Ca rdiomyopa thy

Afte r the a s s ocia tion of the dis e a s e
 with ta urine de ficie ncy, a dditiona l
 ta urine wa s a dde d to comme rcia l die ts
 a nd the incide nce of the dis e a s e
 s ignifica ntly de cre a s e d.
The pa thologic condition is s imila r to
 DCM in dogs .
Evide nce ha s be e n found of a ge ne tic
 pre dis pos ition to DCM in ca ts fe d
 ta urine -de ficie nt die ts .
Fe line Hype rtrophic Ca rdiomyopa thy
The mos t common fe line he a rt dis e a s e .
Cha ra cte rize d by hype rtrophy of the le ft
 ve ntricle .
Compromis e of the le ft ve ntricula r cha mbe r
 re s ults in impa ire d dia s tolic re la xa tion,
 re duction of ve ntricula r filling, a nd ultima te ly
 a n impa irme nt in ca rdia c output.
Ca ts with HCM ma y e xpe rie nce he a rt fa ilure ,
 a rte ria l e mbolis m, a nd s udde n de a th.
Ca nine He a rtworm Dis e a s e

The fe ma le mos quito s e rve s a s a n
 inte rme dia te hos t for Dirofila ria immitis .
The s e microfila ria de ve lop in the
 mos quito for 2-3 we e ks a nd a re the n
 inje cte d into the s kin of a dog through
 a bite .
The infe ctive la rva e migra te within the
 s kin of the ne w hos t for a bout 100
 da ys .
Ca nine He a rtworm Dis e a s e …

Young a dults e nte r the va s cula ture
 a nd migra te to the he a rt whe re the y
 ma ture into a dults .
S ix months a fte r the initia l bite , the
 microfila ria ca n be de te cte d in the
 blood.
The pre s e nce of the pa ra s ite s re s ults
 in right-s ide d he a rt e nla rge me nt a nd
 pulmona ry hype rte ns ion.
Fe line He a rtworm Dis e a s e
Ca ts a re s ome wha t re s is ta nt to D. immitis
 infe ction, ha ving fe w a dult worms , which a re
 e limina te d from the hos t within 2 ye a rs .
Mos t s ymptoms in the ca t re la te to the
 re s pira tory s ys te m (cough, dys pne a ) or GI
 s ys te m (vomiting, a nore xia ).
S udde n de a th of a n a s ymptoma tic ca t is
 fa irly fre que nt.
Ata xia , blindne s s , a nd s e izure s ca n a ls o
 occur.
Murmurs

He a rt murmurs a re a bnorma l s ounds
 ca us e d by bloodflow turbule nce .
  Due to va lvula r or non-va lvula r proble ms .
S ys tolic murmur- occurs be twe e n the
 1 st & 2 nd he a rt s ounds .
Dia s tolic murmur- occurs be twe e n the
 2 nd & 1 st he a rt s ounds .
Murmurs …

Va lvula r murmurs - a s ound due to a
 le a ky or na rrowe d va lve .
  Le a ky (ins ufficie ncy) murmur
  Na rrowing (s te nos is ) murmur
Non-va lvula r murmurs - us ua lly occur
 due to s ome type of a cquire d de fe ct.
  P a te nt Ductus Arte rios us
  Inte ra tria l or Inte rve ntricula r s e pta l de fe ct
Dia gnos tics
The Ele ctroca rdiogra m



               ECG, EKG
Applica tions

Exa ct dia gnos e s of a rrhythmia s he a rd
 on a s culta tion.
Acute ons e t of dys pne a
S hock
Fa inting or s e izure s
Monitoring during a nd a fte r s urge ry
All ca rdia c murmurs
Ca rdiome ga ly found on ra diogra phs
Cya nos is
Re me mbe r…
DEP OLARIZATION: a he a rt mus cle
 contra ction in re s pons e to e le ctrica l
 s timuli.
   Occurs whe n e le ctrolyte s move a cros s
    the ce ll me mbra ne .
   S odium-pota s s ium pump
REP OLARIZATION: he a rt mus cle
 re la xa tion occurs whe n the e le ctrolyte s
 move ba ck a cros s the ce ll me mbra ne
 re nde ring the ce ll re a dy for the ne xt
 e le ctrica l impuls e .
Ele ctroca rdiogra m

A gra phic re cording of e le ctrica l
 pote ntia ls produce d by the he a rt
 mus cle during diffe re nt pha s e s of the
 ca rdia c cycle .
  Ea ch portion of the EKG is like a vis ua l
   “picture ” of a s pe cific a re a of the he a rt.
The Comple x

P wave- corre s ponds to a tria l
 de pola riza tion.
   Ma y be a pos itive or ne ga tive de fle ction.
QRS Comple x- corre s pond to
 ve ntricula r de pola riza tion.
T wa ve - re pre s e nts ve ntricula r
 re pola riza tion.
   Ma y be pos itive or ne ga tive de fle ctions .
   Eve ry QRS comple x MUS T be followe d
    by a T wa ve .
Le a d S ys te ms

A le a d s ys te m a llows you to look a t the
 he a rt from diffe re nt a ngle s .
Lead I- be s t for de te rmining a tria l
 function
Lead II- de te rmine s the function of the
 whole he a rt
Lead III- be s t for te s ting the le ft s ide
 of the he a rt
* * * Lead II is the most often used* * *
Le a d S ys te ms …
***Atta chme nt of the Le a ds ***

BLACK le ft fore a rm
WHITE right fore a rm
RED le ft re a r le g
GREEN right re a r le g
BROWN che s t/grounding
Me a s uring the EKG (The Old Wa y)
EKG ABNORMALITIES
Quick & Dirty Guide to EKG Abnorma litie s

P wave: incre a s e d in a mplitude or
 dura tion- a tria l e nla rge me nt.
R wave: incre a s e d in a mplitude - le ft
 ve ntricula r e nla rge me nt.
S wave: incre a s e d in a mplitude - right
 ve ntricula r e nla rge me nt.
Arrhythmia s

An a rrhythmia is a n a bnorma lity in the
 ra te , re gula rity, or s ite of origin of the
 ca rdia c impuls e .
A dis turba nce in conduction of the
 impuls e s uch tha t the norma l s e que nce
 of a ctiva tion of the a tria a nd ve ntricle s
 is a lte re d.
Arrhythmia Inte rpre ta tion
S te p 1: De te rmine the he a rt ra te .
   Is it ra pid? S low? Norma l?
S te p 2: As s e s s the rhythm.
   S ca n the EKG print out for a bnorma litie s .
S te p 3: Ide ntify the P wa ve s .
   A norma l P wa ve indica te s the impuls e origina te d
    in the S A node .
   Abs e nce of P wa ve s s ignifie s a tria l fibrilla tion or
    a tria l s ta nds till.
   P wa ve s ma y be s upe rimpos e d on the QRS
    comple x in va rious s upra ve ntricula r ta chyca rdia s .
Arrhythmia Inte rpre ta tion…

S te p 4: As s e s s the QRS s ha pe &
 dura tion.
  Abnorma litie s in the s ha pe ca n s ugge s t a
   dis turba nce of ve ntricula r impuls e s .
Arrhythmia Inte rpre ta tion…
S te p 5: Look a t the re la tions hip be twe e n the
 P wa ve s a nd the QRS comple xe s .
   Norma lly, the re s hould be one P wa ve for e ve ry
    QRS comple x with a cons ta nt P -R inte rva l.
   Long P -R inte rva ls indica te a n AV conduction
    de la y (1° AV block).
   A P wa ve not followe d by a QRS comple x
    indica te s 2˚ AV block.
   P -R inte rva ls tha t va ry indica te 3˚ AV block.
Norma l S inus Rhythm
 P wa ve s a re pos itive .
 QRS comple xe s a re norma l with a cons ta nt P -R
  inte rva l.
 This is NORMAL.
S INUS IMP ULS E
DIS TURBANCES
S inus Arrhythmia

An irre gula r rhythm origina ting in the
 S A node .
Re pre s e nte d by a lte rna ting pe riods of
 s lowe r & more ra pid he a rt ra te s .
Us ua lly re la te d to re s pira tion:
  He a rt ra te incre a s e s with ins pira tion a nd
   de cre a s e s with e xpira tion.
A fre que nt norma l finding in the dog.
S inus Arrhythmia …




 Ofte n s e e n in bra chyce pha lic bre e ds or in chronic
  re s pira tory dis e a s e s , in which va ga l tone is
  incre a s e d by uppe r a irwa y obs truction.
 Atropine e limina te s re s pira tory induce d S A.
S inus Arrhythmia …
S inus Bra dyca rdia
 A re gula r rhythm, with a s low he a rt ra te .
 In ca ts , it is ofte n a s s ocia te d with a s e rious
  unde rlying dis orde r, which re quire s imme dia te
  a tte ntion.
 Ca us e s - intuba tion, hypothe rmia , & re s pira tory
  dis e a s e .
S inus Ta chyca rdia
A re gula r s inus rhythm, with a fa s t he a rt ra te .
The mos t common a rrhythmia in dogs a nd
 ca ts .
P hys iologic ca us e s include : e xe rcis e , pa in,
 or proce dure s involving re s tra int.
P a thologic ca us e s include : fe ve r,
 hype rthyroidis m, s hock, a ne mia , infe ction,
 CHF, & hypoxia .
Drugs include : a tropine a nd e pine phe rine .
S inus Ta chyca rdia …
S UP RAVENTRICULAR
IMP ULS E DIS TURBANCES
Atria l P re ma ture Contra ctions

Ca us e d by impuls e s origina ting from a
 s ite othe r tha n the S A node .
The he a rt ra te is us ua lly norma l.
The P -R inte rva l ma y be long.
A pa us e us ua lly follows a n AP C.
S e e n in both dogs a nd ca ts , us ua lly a
 re s ult of a tria l e nla rge me nt (e .g., mitra l
 ins ufficie ncy, ca rdiomyopa thy).
Atria l P re ma ture Contra ctions …
Atria l Ta chyca rdia
A ra pid re gula r rhythm origina ting from a s ite
 othe r tha n the S A node .
Thre e or more AP C’s .
Atria l Fibrilla tion

Ca us e d by nume rous dis orga nize d
 a tria l impuls e s bomba rding the AV
 node .
Ha s a ra pid a nd tota lly irre gula r a tria l
 a nd ve ntricula r ra te .
No P wa ve s .
Commonly s e e n in conditions
 a s s ocia te d with a tria l e nla rge me nt, or
 dia lte d ca rdiomyopa thy.
Atria l Fibrilla tion…
VENTRICULAR IMP ULS E
   DIS TURBANCES
Ve ntricula r P re ma ture Contra ctions

Ca rdia c impuls e s initia te d in the
 ve ntricle s ins te a d of the S A node .
As s ocia te d with we a kne s s , e xe rcis e
 intole ra nce , & s udde n de a th.
QRS comple xe s a re typica lly wide a nd
 biza rre .
P wa ve s a re dis s ocia te d from the QRS
 comple x.
Ve ntricula r P re ma ture Contra ctions …

A VP C is us ua lly followe d by a pa us e .
Commonly s e e n in la rge bre e d dogs
 with ca rdiomyopa thy, e s pe cia lly boxe rs
 a nd Dobie s .
Common in ca ts with ca rdiomyopa thy;
 occa s iona lly s e e n in ca ts with
 hype rthyroidis m.
Ve ntricula r P re ma ture Contra ctions …
Ve ntricula r P re ma ture Contra ctions …
Ve ntricula r Ta chyca rdia

Thre e or more VP C’s in a row.
The ve ntricula r ra te is >150 bpm.
QRS comple xe s a re wide a nd biza rre .
The re is no re la tions hip be twe e n the P
 wa ve s a nd the QRS comple xe s .
  The P wa ve s ma y pre ce de , be hidde n
   within, or follow the QRS comple xe s .
Ve ntricula r Ta chyca rdia …
Ve ntricula r Fibrilla tion

Occurs whe n the ce lls of the
 ve ntricula r myoca rdium de pola rize in a
 cha otic a nd uncoordina te d ma nne r.
No puls e ca n be fe lt a nd ca rdia c
 output a pproa che s ze ro.
No QRS comple xe s or P wa ve s .
Ve ntricula r Fibrilla tion…
                      As s ocia te d
                       conditions include :
                         S hock,
                         Myoca rdia l
                          infa rction,
                         Ele ctrolyte & a cid-
                          ba s e imba la nce s ,
                         Aortic s te nos is
                         Hypothe rmia
Ve ntricula r As ys tole

Indica te s the a bs e nce of a ny
 pa ce ma ke r impuls e s .
S ubs e que ntly, the re is no
 de pola riza tion or contra ction of the
 ve ntricle s .
No puls e ca n be fe lt a nd ca rdia c
 output a pproa che s ze ro.
P wa ve s ma y be pre s e nt if the a nima l
 ha s comple te AV block.
Ve ntricula r As ys tole …
No QRS comple xe s .
IMP ULS E CONDUCTION
    DIS TURBANCES
Atria l S ta nds till
 Cha ra cte rize d by a n a bs e nce of P wa ve s .
 P a tie nts ha ve S A node function, but impuls e s do not
  ca us e myocyte a ctiva tion.
 Ca us e s include hype rka le mia a nd a tria l dis e a s e .
Firs t-De gre e AV Block

A de la y in the conduction of a n
 impuls e through the AV node a nd
 bundle of His .
Us ua lly cha ra cte rize d by a prolonge d
 P -R inte rva l.
Ge ne ra lly s e e n in olde r pa tie nts
 s e conda ry to de ge ne ra tive cha nge s in
 the conduction s ys te m.
Firs t-De gre e AV Block…
S e cond-De gre e AV Block
 Cha ra cte rize d by a n inte rmitte nt fa ilure or dis turba nce of AV
  conduction.
 One or more P wa ve s a re not followe d by QRS comple xe s .
 P -R inte rva l is ofte n va ria ble .
Third-De gre e AV Block

The ca rdia c impuls e is comple te ly
 blocke d in the re gion of the AV
 junction.
The P wa ve is norma l.
The QRS comple x is wide a nd biza rre .
The re is no conduction be twe e n the
 a tria a nd ve ntricle s .
Third-De gre e AV Block…
II. Circula tory S ys te m
Circula tory S ys te m
Cons is ts of the he a rt, blood ve s s e ls ,
 a nd lympha tics .
   Blood a cquire s oxyge n in the lungs ,
    nutrie nts from the dige s tive tra ct, a nd
    hormone s from e ndocrine gla nds .
Blood Vascular System- cons is ts of
 blood, he a rt, a rte rie s , ca pilla rie s , &
 ve ins .
Circula tory S ys te m…
Artery- a ve s s e l ca rrying blood a wa y
 from the he a rt.
  Ge ne ra lly thicke r a nd s tronge r tha n ve ins .
Capillary- a micros copic ve s s e l tha t
 joins othe rs to form a n e xte ns ive
 ne twork.
  P os itione d be twe e n a rte rie s a nd ve ins .
  The y a llow e xcha nge of ga s s e s a nd
   nutrie nts be twe e n the blood a nd inte rs titia l
   fluid.
Circula tory S ys te m…

Veins- ve s s e ls ca rrying blood towa rds
 the he a rt.
  Thinne r-wa lle d, the y ca rry a gre a te r
   volume tha n a rte rie s .
Circula tory S ys te m…
Arte rie s  a rte riole s  ca pilla rie s 
 ve nule s  ve ins
Circula tory S ys te m…

Va lve s in ve ins e ns ure tha t blood
 tra ve ls only in the dire ction of the
 he a rt.
Cons triction a nd re la xa tion a llow the
 va s cula r s ys te m to dire ct blood to
 diffe re nt pa rts of the body, a nd to
 ma inta in blood pre s s ure whe n blood
 volume or ca rdia c output is de cre a s e d.
Nota ble Ve s s e ls

Re me mbe r… for e ve ry a rte ry ta king
 fre s h blood to the body, the re is a ve in
 to ca rry de oxyge na te d blood ba ck to
 the he a rt– jus t like on a nd off ra mps to
 the “ma jor highwa y!
Fe line Thromboe mbolis m


 a .k.a . a s a ddle thrombus
 Cla s s ic pre s e nta tion is pos te rior
  pa re s is with we a k or a bs e nt puls e s
  in the re a r limbs ; foot pa ds a re
  pa le , a nd the toe na ils won’t ble e d
  whe n quicke d; the ga s trocne mius
  a nd tibia l mus cle s a re rock ha rd by
  10-12 hrs pos t-clot
 Aggre s s ive thrombolytic the ra py
  ma y be ins titute d if the clinicia n
  fe e ls the thrombus is re ce nt (2-4
  hrs ) a nd the he a rt dis e a s e is
  ma na ge a ble but the prognos is is
  s till gua rde d
Fe line Thromboe mbolis m (cont)

 Mos t common s ite is a t the
  a ortic trifurca tion
 Clinica l s igns de pe nd on
  the de gre e of he a rt dis e a s e
  a nd the s ite of
  thromboe mbolis m
 It ma y be the firs t s ign of
  he a rt dis e a s e or
  s ome time s ca ts will s how
  s e ve re s igns of CHF
THE END!
Lp 12 cardiovascular
Lp 12 cardiovascular

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Lp 12 cardiovascular

  • 1. VTT 235/245 Ana tomy & P a thology La b for Ve te rina ry Te chnicia ns Ca rdiova s cula r S ys te m I. Ca rdia c S ys te m II. Circula tory S ys te m
  • 2. Ca rdia c S ys te m The ma jor function of the CVS is tra ns porta tion, with blood be ing the tra ns port ve hicle . Circula tory P a ths - Systemic Circulation- is blood flow to a nd from mos t pa rts of the body. Pulmonary Circulation- is blood flow to a nd from the lungs , during which it picks up oxyge n a nd re turns it to the he a rt.
  • 3. Ca rdia c S ys te m Circula tory P a ths - Coronary Circulation- blood flow to the he a rt mus cle its e lf. Portal Circulation- a ve nous s ys te m in which blood re turns from the inte s tine s a nd proce e ds to the live r be fore re turning to the he a rt. * * Venous System- re turns blood to the he a rt. Arterial System- ca rrie s blood a wa y from the he a rt.
  • 4.
  • 5. He a rt A mus cula r, four cha mbe re d orga n tha t drive s the circula tory s ys te m. Lie s in the mediastinum. Base- top of the he a rt. Apex- bottom of the he a rt.
  • 6. He a rt… The oute r la ye r of the he a rt is ca lle d the pericardium. The pe rica rdium cons is ts of 2 la ye rs : An oute r fibrous pericardium- ma de of tough, fibrous CT tha t prote cts the he a rt a nd loos e ly a tta che s it to the dia phra gm. An inne r serous pericardium- which is a ls o ma de of 2 la ye rs : Inner Visceral layer(epicardium) Outer parietal layer
  • 7. He a rt… Ins ide the s a c forme d by the pe rica rdium is the thicke s t la ye r of he a rt tis s ue , the myocardium. Be twe e n the cha mbe rs a nd the myoca rdium is a thin me mbra nous lining ca lle d the endocardium.
  • 8. He a rt… Compartments- the he a rt ha s 4 cha mbe rs . The 2 a tria re ce ive blood a nd pump it down into the re s pe ctive ve ntricle s , which pump it a wa y from the he a rt. Right Atrium- compa rtme nt re ce iving de oxyge na te d blood. Interatrial septum- the wa ll s e pa ra ting the a tria . Fossa Ovale- a re mna nt of the fe ta l fora me n ova le .
  • 9. He a rt… Right Ventricle- compa rtme nt re ce iving blood from the right a trium. The right ve ntricula r wa ll is thinne r be ca us e le s s pre s s ure is re quire d to move blood through the lungs tha n through the body. Ventricular septum- s e pa ra te s the ve ntricle s .
  • 10. He a rt… Left Atrium- the compa rtme nt re ce iving oxyge na te d blood from the lungs via the pulmona ry ve ins . Left Ventricle- compa rtme nt re ce iving oxyge na te d blood from the le ft a trium a nd s e nding it out the a orta to the body (s ys te mic circula tion). The le ft ve ntricula r wa ll is thicke r be ca us e of the highe r pre s s ure re quire d for s ys te mic circula tion.
  • 11. He a rt… Ve ntricula r S tructure s - Papillary Muscles- mus cula r proje ctions s e rving a s a tta chme nts for the chorda e te ndine a e of the AV va lve s . Chordae Tendineae- tough s tra nds a nchoring the fre e e dge s of the AV va lve s to the pa pilla ry mus cle s .
  • 12. He a rt… Va lve s - AV Va lve s - pre ve nt ba ckflow into the a tria during ve ntricula r (s ys tole ) contra ctions . Right AV (tricus pid) va lve Le ft AV (bicus pid/mitra l) va lve “Tri” before you “bi” !!! S e mi-luna r va lve s - Aortic P ulmona ry
  • 13. Ma jor Ve s s e ls Cranial Vena Cava- the la rge ve in re turning blood from the he a d, ne ck, a nd thora cic limbs to the right a trium. Caudal Vena Cava- la rge ve in re turning blood from pa rt of the thora x, vis ce ra , a nd the ca uda l pa rt of the body to the right a trium.
  • 14. Ma jor Ve s s e ls … Pulmonary Trunk- the la rge ve s s e l ca rrying blood from the right ve ntricle to the pulmona ry a rte rie s , a nd thus , to the lungs . Pulmonary Arteries- the two bra nche s of the pulmona ry trunk ca rrying blood to the right a nd le ft lung lobe s .
  • 15. Ma jor Ve s s e ls … Pulmonary Veins- the nume rous ve s s e ls e mptying oxyge na te d blood into the le ft a trium. Aorta- ma jor outflow from the le ft ve ntricle into the s ys te mic circula tion.
  • 16. Ca rdia c Cycle Both a tria contra ct a t virtua lly the s a me time . Blood e nte rs the a tria while the y a re re la xe d. The atrioventricular (AV) valves a re ope n s o blood flows ra pidly through the ve ntricle s . Approxima te ly 70% of ve ntricle filling occurs during this pha s e .
  • 17. Ca rdia c Cycle … The a tria the n contra ct, which is ca lle d a tria l s ys tole , a nd the ve ntricle s fill comple te ly. Ne xt, both ve ntricle s contra ct a nd the AV va lve s a re force d to clos e , producing the firs t a udible he a rt s ound. P re s s ure on the ve ntricle s ca us e the s e mi-luna r va lve s to ope n a nd blood is e je cte d into the pulmona ry a rte ry a nd a orta .
  • 18. Ca rdia c Cycle … This contra ction is ca lle d ventricular systole. The s e mi-luna r va lve s clos e producing the s e cond he a rt s ound. The cycle is re pe a te d with the pe riod of re la xa tion ca lle d diastole.
  • 19. How Blood P umps Through the He a rt  The Right Atrium, re ce ive s “de oxyge na te d blood" from the body. Blood will be pus he d through the tricus pid va lve to the  Right Ve ntricle , the cha mbe r which will pump to the lungs through the pulmonic va lve to the  P ulmona ry Arte rie s , providing blood to both lungs . Blood is circula te d through the lungs whe re ca rbon dioxide is re move d a nd oxyge n a dde d. It re turns through the  P ulmona ry Ve ins , which e mpty into the  Le ft Atrium, (oxyge na te d blood) a cha mbe r which will pus h the Mitra l Va lve ope n. Blood the n pa s s e s into the  Le ft Ve ntricle . Although it doe s n't a lwa ys look like it in dra wings done from this a ngle , this is the la rge s t a nd mos t importa nt cha mbe r in the he a rt. It pumps to the re s t of the body. As it pumps , the pre s s ure will clos e the mitra l va lve a nd ope n the a ortic va lve , with blood pa s s ing through to the  Aorta , whe re it will be de live re d to the re s t of the body.
  • 20. He a rt Ra te & Ca rdia c Output Cardiac output- the a mount of blood tha t le a ve s the he a rt. De te rmine d by: Stroke Volume- the a mount of blood e je cte d with e a ch ca rdia c contra ction. Heart Rate- how ofte n the he a rt contra cts .
  • 21. Conduction S ys te m Ea ch comple te contra ction a nd re la xa tion is ca lle d a cardiac cycle. Two ma in pa rts - Systole- whe n the he a rt mus cle contra cts a nd blood is e je cte d from the a tria to the ve ntricle s a nd out the a orta . Diastole- the he a rt re la xe s a nd re fills with blood.
  • 22. Conduction S ys te m… The impuls e come s from the SA node. A s pe cia lize d a re a of ca rdia c mus cle ce lls tha t pos s e s the a bility of a utoma tica lly ge ne ra ting the e le ctrica l impuls e s tha t trigge r the re pe a te d be a ting of the he a rt.
  • 23. Conduction S ys te m… The S A node ge ne ra te s a n e le ctrica l curre nt by the move me nt of ca tions a cros s the oute r me mbra ne s of it’s ce lls .
  • 24. Conduction S ys te m… This proce s s ca lle d depolarization, ge ne ra te s a n e le ctrica l curre nt which ca us e s the he a rt mus cle to contra ct. Ca rdia c mus cle ca n tra ns mit a n impuls e from one ce ll to a nothe r, s o e le ctrica l impuls e s a nd contra ctions s pre a d a cros s the he a rt like a wa ve . Afte r the impuls e is ge ne ra te d in the S A node , it s pre a ds in a wa ve a cros s both a tria , ca us ing the to contra ct a nd pus h blood through the AV va lve s into the ve ntricle s , which a re s till re la xe d.
  • 25. Conduction S ys te m… The impuls e tra ve ls to the AV node whe re it e ncounte rs a s light de la y. This is the only conduction route from the a tria to the ve ntricle s . The de la y pe rmits the a tria to comple te the ir s ys tolic contra ction be fore ve ntricula r s ys tole be gins . Afte r the AV node , it tra ve ls to the s pe cia lize d fibe rs in the ve ntricle s ca lle d the bundle of His & the Purkinje fibers.
  • 26.
  • 28. He a rt Fa ilure Whe n blood re turning to the he a rt ca nnot be pumpe d out a t a ra te ma tching the body’s ne e ds . Ma ny ca us e s e xis t. Mus t de te rmine if the fa ilure is a re s ult of myoca rdia l dys function (pump fa ilure ) or circula tory fa ilure (la ck of circula ting fluid volume . Conge s tive He a rt Fa ilure - whe n the fa iling he a rt a llows fluid conge s tion a nd e de ma to a ccumula te in the body.
  • 29. Congestive Heart Failure A de ge ne ra tive dis e a s e whe re the va lve le a fle ts be come knobby a nd thicke ne d. Re gurgita ting blood ca us e s e nla rge me nt of the le ft a trium a nd le ft ve ntricle Mitra l re gurgita tion mos t common ca us e ; 30% of s ma ll bre e d dogs > 10 ye a rs old a re a ffe cte d P re dis pos e d bre e ds include Ca va lie r King Cha rle s S pa nie ls , P oodle s , Mini S chna uze rs , Chihua hua s , Cocke r S pa nie ls , Da chs hunds , Bos ton Te rrie rs , & Fox Te rrie rs P rogre s s ion of the dis e a s e ca n ta ke ye a rs
  • 30. CHF (cont) P re s e nt with ta chypne a , ha rs h lung s ounds , ins pira tory cra ckle s tha t progre s s to cra ckle s /whe e ze s throughout re s pira tion with a dis tinguis ha ble he a rt murmur CHF a nima ls a re lite ra lly drowning in the ir own fluids .
  • 31. P a te nt Ductus Arte rios is (P DA)-  Mos t common conge nita l he a rt de fe ct of dogs  The duct be twe e n the le ft pulmona ry a rte ry a nd the de s ce nding a orta in the fe tus doe s not clos e a t birth  Re s ults in le ft s ide d CHF  The re s ulting murmur is ofte n re fe rre d to a s a “ma chine ry murmur”.
  • 32. Va lvula r S te nos is A na rrowing of one of the he a rt va lve s Ma y be a ortic or pulmonic Ca us e s va rious type s of murme rs
  • 33. P e rs is te nt Right Aortic Arch P RAA The mos t common va s cula r ring a noma ly Ca us e s a n obs truction of the e s opha gus Re gurgita tion, a nd a s pira tion pne umonia a re s ome s igns in young we a ning a nima ls
  • 34. P a te nt Ova le Fora me n A.K.A. Inte ra tria l S e pta l De fe ct Fa ilure of the ope ning be twe e n the two fe ta l a tria to clos e .
  • 35. Chronic Mitra l Va lve Ins ufficie ncy CMVI is the mos t commonly e ncounte re d a cquire d ca rdia c dis orde rs in the dog. One of the mos t common ca us e s is chronic pe riodonta l dis e a s e . Ba cte ria living in ta rta r a re s howe re d into the bloods tre a m, colonizing on the va lve le a fle ts of the he a rt. The s tiff, ma lforme d le a fle ts fa il to clos e s ufficie ntly during s ys tole , re s ulting in re gurgita tion ba ck up into the a trium.
  • 36. Ca nine Dila te d Ca rdiomyopa thy One of the mos t common a cquire d ca rdiova s cula r dis e a s e s of dogs . P rima rily a dis e a s e of olde r, ma le la rge & gia nt bre e d dogs . The dis e a s e involve s the dila tion of a ll four cha mbe rs of the he a rt. This dila tion (ca us e d by we a k, thin, & fla bby ca rdia c mus cle ) re s ults in: A de cre a s e in ca rdia c output. An incre a s e in ca rdia c a fte rloa d (blood le ft in the he a rt in dia s tole ).
  • 37. DCM… The e xa ct ca us e is unknown, a lthough vira l, nutritiona l, immune -me dia te d, a nd ge ne tic ca us e s ha ve be e n propos e d. DCM re s ults in impa ire d s ys tolic function of the ve ntricle s a nd, the re fore , de cre a s e d s troke volume . The volume of blood e je cte d from the he a rt with e a ch contra ction.
  • 38. DCM… The e ffe ct on the a nima l is one of low- output circula tory fa ilure , e xhibite d by: We a kne s s Exe rcis e intole ra nce S yncope S hock
  • 39. DCM… Dogs with DCM fre que ntly e xpe rie nce the de ve lopme nt of a tria l fibrilla tion, which furthe r contribute s to a de cre a s e in ca rdia c output. S igns of a tria l fibrilla tion include ra pid, irre gula r he a rt rhythms or s udde n de a th.
  • 40. Ca nine Hype rtrophic Ca rdiomyopa thy An uncommon ca nine dis e a s e . The le ft ve ntricula r mus cle a trophie s de cre a s ing the filling ca pa city of the ve ntricle a nd ofte n blocking the outflow of blood during s ys tole .
  • 41. Fe line Dila te d Ca rdiomyopa thy Afte r the a s s ocia tion of the dis e a s e with ta urine de ficie ncy, a dditiona l ta urine wa s a dde d to comme rcia l die ts a nd the incide nce of the dis e a s e s ignifica ntly de cre a s e d. The pa thologic condition is s imila r to DCM in dogs . Evide nce ha s be e n found of a ge ne tic pre dis pos ition to DCM in ca ts fe d ta urine -de ficie nt die ts .
  • 42. Fe line Hype rtrophic Ca rdiomyopa thy The mos t common fe line he a rt dis e a s e . Cha ra cte rize d by hype rtrophy of the le ft ve ntricle . Compromis e of the le ft ve ntricula r cha mbe r re s ults in impa ire d dia s tolic re la xa tion, re duction of ve ntricula r filling, a nd ultima te ly a n impa irme nt in ca rdia c output. Ca ts with HCM ma y e xpe rie nce he a rt fa ilure , a rte ria l e mbolis m, a nd s udde n de a th.
  • 43. Ca nine He a rtworm Dis e a s e The fe ma le mos quito s e rve s a s a n inte rme dia te hos t for Dirofila ria immitis . The s e microfila ria de ve lop in the mos quito for 2-3 we e ks a nd a re the n inje cte d into the s kin of a dog through a bite . The infe ctive la rva e migra te within the s kin of the ne w hos t for a bout 100 da ys .
  • 44. Ca nine He a rtworm Dis e a s e … Young a dults e nte r the va s cula ture a nd migra te to the he a rt whe re the y ma ture into a dults . S ix months a fte r the initia l bite , the microfila ria ca n be de te cte d in the blood. The pre s e nce of the pa ra s ite s re s ults in right-s ide d he a rt e nla rge me nt a nd pulmona ry hype rte ns ion.
  • 45. Fe line He a rtworm Dis e a s e Ca ts a re s ome wha t re s is ta nt to D. immitis infe ction, ha ving fe w a dult worms , which a re e limina te d from the hos t within 2 ye a rs . Mos t s ymptoms in the ca t re la te to the re s pira tory s ys te m (cough, dys pne a ) or GI s ys te m (vomiting, a nore xia ). S udde n de a th of a n a s ymptoma tic ca t is fa irly fre que nt. Ata xia , blindne s s , a nd s e izure s ca n a ls o occur.
  • 46. Murmurs He a rt murmurs a re a bnorma l s ounds ca us e d by bloodflow turbule nce . Due to va lvula r or non-va lvula r proble ms . S ys tolic murmur- occurs be twe e n the 1 st & 2 nd he a rt s ounds . Dia s tolic murmur- occurs be twe e n the 2 nd & 1 st he a rt s ounds .
  • 47. Murmurs … Va lvula r murmurs - a s ound due to a le a ky or na rrowe d va lve . Le a ky (ins ufficie ncy) murmur Na rrowing (s te nos is ) murmur Non-va lvula r murmurs - us ua lly occur due to s ome type of a cquire d de fe ct. P a te nt Ductus Arte rios us Inte ra tria l or Inte rve ntricula r s e pta l de fe ct
  • 49. The Ele ctroca rdiogra m ECG, EKG
  • 50. Applica tions Exa ct dia gnos e s of a rrhythmia s he a rd on a s culta tion. Acute ons e t of dys pne a S hock Fa inting or s e izure s Monitoring during a nd a fte r s urge ry All ca rdia c murmurs Ca rdiome ga ly found on ra diogra phs Cya nos is
  • 51. Re me mbe r… DEP OLARIZATION: a he a rt mus cle contra ction in re s pons e to e le ctrica l s timuli. Occurs whe n e le ctrolyte s move a cros s the ce ll me mbra ne . S odium-pota s s ium pump REP OLARIZATION: he a rt mus cle re la xa tion occurs whe n the e le ctrolyte s move ba ck a cros s the ce ll me mbra ne re nde ring the ce ll re a dy for the ne xt e le ctrica l impuls e .
  • 52. Ele ctroca rdiogra m A gra phic re cording of e le ctrica l pote ntia ls produce d by the he a rt mus cle during diffe re nt pha s e s of the ca rdia c cycle . Ea ch portion of the EKG is like a vis ua l “picture ” of a s pe cific a re a of the he a rt.
  • 53.
  • 54. The Comple x P wave- corre s ponds to a tria l de pola riza tion. Ma y be a pos itive or ne ga tive de fle ction. QRS Comple x- corre s pond to ve ntricula r de pola riza tion. T wa ve - re pre s e nts ve ntricula r re pola riza tion. Ma y be pos itive or ne ga tive de fle ctions . Eve ry QRS comple x MUS T be followe d by a T wa ve .
  • 55.
  • 56. Le a d S ys te ms A le a d s ys te m a llows you to look a t the he a rt from diffe re nt a ngle s . Lead I- be s t for de te rmining a tria l function Lead II- de te rmine s the function of the whole he a rt Lead III- be s t for te s ting the le ft s ide of the he a rt * * * Lead II is the most often used* * *
  • 57. Le a d S ys te ms …
  • 58. ***Atta chme nt of the Le a ds *** BLACK le ft fore a rm WHITE right fore a rm RED le ft re a r le g GREEN right re a r le g BROWN che s t/grounding
  • 59.
  • 60. Me a s uring the EKG (The Old Wa y)
  • 61.
  • 63. Quick & Dirty Guide to EKG Abnorma litie s P wave: incre a s e d in a mplitude or dura tion- a tria l e nla rge me nt. R wave: incre a s e d in a mplitude - le ft ve ntricula r e nla rge me nt. S wave: incre a s e d in a mplitude - right ve ntricula r e nla rge me nt.
  • 64. Arrhythmia s An a rrhythmia is a n a bnorma lity in the ra te , re gula rity, or s ite of origin of the ca rdia c impuls e . A dis turba nce in conduction of the impuls e s uch tha t the norma l s e que nce of a ctiva tion of the a tria a nd ve ntricle s is a lte re d.
  • 65. Arrhythmia Inte rpre ta tion S te p 1: De te rmine the he a rt ra te . Is it ra pid? S low? Norma l? S te p 2: As s e s s the rhythm. S ca n the EKG print out for a bnorma litie s . S te p 3: Ide ntify the P wa ve s . A norma l P wa ve indica te s the impuls e origina te d in the S A node . Abs e nce of P wa ve s s ignifie s a tria l fibrilla tion or a tria l s ta nds till. P wa ve s ma y be s upe rimpos e d on the QRS comple x in va rious s upra ve ntricula r ta chyca rdia s .
  • 66. Arrhythmia Inte rpre ta tion… S te p 4: As s e s s the QRS s ha pe & dura tion. Abnorma litie s in the s ha pe ca n s ugge s t a dis turba nce of ve ntricula r impuls e s .
  • 67. Arrhythmia Inte rpre ta tion… S te p 5: Look a t the re la tions hip be twe e n the P wa ve s a nd the QRS comple xe s . Norma lly, the re s hould be one P wa ve for e ve ry QRS comple x with a cons ta nt P -R inte rva l. Long P -R inte rva ls indica te a n AV conduction de la y (1° AV block). A P wa ve not followe d by a QRS comple x indica te s 2˚ AV block. P -R inte rva ls tha t va ry indica te 3˚ AV block.
  • 68. Norma l S inus Rhythm  P wa ve s a re pos itive .  QRS comple xe s a re norma l with a cons ta nt P -R inte rva l.  This is NORMAL.
  • 69. S INUS IMP ULS E DIS TURBANCES
  • 70. S inus Arrhythmia An irre gula r rhythm origina ting in the S A node . Re pre s e nte d by a lte rna ting pe riods of s lowe r & more ra pid he a rt ra te s . Us ua lly re la te d to re s pira tion: He a rt ra te incre a s e s with ins pira tion a nd de cre a s e s with e xpira tion. A fre que nt norma l finding in the dog.
  • 71. S inus Arrhythmia …  Ofte n s e e n in bra chyce pha lic bre e ds or in chronic re s pira tory dis e a s e s , in which va ga l tone is incre a s e d by uppe r a irwa y obs truction.  Atropine e limina te s re s pira tory induce d S A.
  • 73. S inus Bra dyca rdia  A re gula r rhythm, with a s low he a rt ra te .  In ca ts , it is ofte n a s s ocia te d with a s e rious unde rlying dis orde r, which re quire s imme dia te a tte ntion.  Ca us e s - intuba tion, hypothe rmia , & re s pira tory dis e a s e .
  • 74. S inus Ta chyca rdia A re gula r s inus rhythm, with a fa s t he a rt ra te . The mos t common a rrhythmia in dogs a nd ca ts . P hys iologic ca us e s include : e xe rcis e , pa in, or proce dure s involving re s tra int. P a thologic ca us e s include : fe ve r, hype rthyroidis m, s hock, a ne mia , infe ction, CHF, & hypoxia . Drugs include : a tropine a nd e pine phe rine .
  • 75. S inus Ta chyca rdia …
  • 76. S UP RAVENTRICULAR IMP ULS E DIS TURBANCES
  • 77. Atria l P re ma ture Contra ctions Ca us e d by impuls e s origina ting from a s ite othe r tha n the S A node . The he a rt ra te is us ua lly norma l. The P -R inte rva l ma y be long. A pa us e us ua lly follows a n AP C. S e e n in both dogs a nd ca ts , us ua lly a re s ult of a tria l e nla rge me nt (e .g., mitra l ins ufficie ncy, ca rdiomyopa thy).
  • 78. Atria l P re ma ture Contra ctions …
  • 79. Atria l Ta chyca rdia A ra pid re gula r rhythm origina ting from a s ite othe r tha n the S A node . Thre e or more AP C’s .
  • 80. Atria l Fibrilla tion Ca us e d by nume rous dis orga nize d a tria l impuls e s bomba rding the AV node . Ha s a ra pid a nd tota lly irre gula r a tria l a nd ve ntricula r ra te . No P wa ve s . Commonly s e e n in conditions a s s ocia te d with a tria l e nla rge me nt, or dia lte d ca rdiomyopa thy.
  • 81. Atria l Fibrilla tion…
  • 82. VENTRICULAR IMP ULS E DIS TURBANCES
  • 83. Ve ntricula r P re ma ture Contra ctions Ca rdia c impuls e s initia te d in the ve ntricle s ins te a d of the S A node . As s ocia te d with we a kne s s , e xe rcis e intole ra nce , & s udde n de a th. QRS comple xe s a re typica lly wide a nd biza rre . P wa ve s a re dis s ocia te d from the QRS comple x.
  • 84. Ve ntricula r P re ma ture Contra ctions … A VP C is us ua lly followe d by a pa us e . Commonly s e e n in la rge bre e d dogs with ca rdiomyopa thy, e s pe cia lly boxe rs a nd Dobie s . Common in ca ts with ca rdiomyopa thy; occa s iona lly s e e n in ca ts with hype rthyroidis m.
  • 85. Ve ntricula r P re ma ture Contra ctions …
  • 86. Ve ntricula r P re ma ture Contra ctions …
  • 87. Ve ntricula r Ta chyca rdia Thre e or more VP C’s in a row. The ve ntricula r ra te is >150 bpm. QRS comple xe s a re wide a nd biza rre . The re is no re la tions hip be twe e n the P wa ve s a nd the QRS comple xe s . The P wa ve s ma y pre ce de , be hidde n within, or follow the QRS comple xe s .
  • 88. Ve ntricula r Ta chyca rdia …
  • 89. Ve ntricula r Fibrilla tion Occurs whe n the ce lls of the ve ntricula r myoca rdium de pola rize in a cha otic a nd uncoordina te d ma nne r. No puls e ca n be fe lt a nd ca rdia c output a pproa che s ze ro. No QRS comple xe s or P wa ve s .
  • 90. Ve ntricula r Fibrilla tion… As s ocia te d conditions include : S hock, Myoca rdia l infa rction, Ele ctrolyte & a cid- ba s e imba la nce s , Aortic s te nos is Hypothe rmia
  • 91. Ve ntricula r As ys tole Indica te s the a bs e nce of a ny pa ce ma ke r impuls e s . S ubs e que ntly, the re is no de pola riza tion or contra ction of the ve ntricle s . No puls e ca n be fe lt a nd ca rdia c output a pproa che s ze ro. P wa ve s ma y be pre s e nt if the a nima l ha s comple te AV block.
  • 92. Ve ntricula r As ys tole … No QRS comple xe s .
  • 93. IMP ULS E CONDUCTION DIS TURBANCES
  • 94. Atria l S ta nds till  Cha ra cte rize d by a n a bs e nce of P wa ve s .  P a tie nts ha ve S A node function, but impuls e s do not ca us e myocyte a ctiva tion.  Ca us e s include hype rka le mia a nd a tria l dis e a s e .
  • 95. Firs t-De gre e AV Block A de la y in the conduction of a n impuls e through the AV node a nd bundle of His . Us ua lly cha ra cte rize d by a prolonge d P -R inte rva l. Ge ne ra lly s e e n in olde r pa tie nts s e conda ry to de ge ne ra tive cha nge s in the conduction s ys te m.
  • 96. Firs t-De gre e AV Block…
  • 97. S e cond-De gre e AV Block  Cha ra cte rize d by a n inte rmitte nt fa ilure or dis turba nce of AV conduction.  One or more P wa ve s a re not followe d by QRS comple xe s .  P -R inte rva l is ofte n va ria ble .
  • 98. Third-De gre e AV Block The ca rdia c impuls e is comple te ly blocke d in the re gion of the AV junction. The P wa ve is norma l. The QRS comple x is wide a nd biza rre . The re is no conduction be twe e n the a tria a nd ve ntricle s .
  • 99. Third-De gre e AV Block…
  • 100.
  • 101.
  • 102.
  • 103. II. Circula tory S ys te m
  • 104. Circula tory S ys te m Cons is ts of the he a rt, blood ve s s e ls , a nd lympha tics . Blood a cquire s oxyge n in the lungs , nutrie nts from the dige s tive tra ct, a nd hormone s from e ndocrine gla nds . Blood Vascular System- cons is ts of blood, he a rt, a rte rie s , ca pilla rie s , & ve ins .
  • 105. Circula tory S ys te m… Artery- a ve s s e l ca rrying blood a wa y from the he a rt. Ge ne ra lly thicke r a nd s tronge r tha n ve ins . Capillary- a micros copic ve s s e l tha t joins othe rs to form a n e xte ns ive ne twork. P os itione d be twe e n a rte rie s a nd ve ins . The y a llow e xcha nge of ga s s e s a nd nutrie nts be twe e n the blood a nd inte rs titia l fluid.
  • 106. Circula tory S ys te m… Veins- ve s s e ls ca rrying blood towa rds the he a rt. Thinne r-wa lle d, the y ca rry a gre a te r volume tha n a rte rie s .
  • 107. Circula tory S ys te m… Arte rie s  a rte riole s  ca pilla rie s  ve nule s  ve ins
  • 108. Circula tory S ys te m… Va lve s in ve ins e ns ure tha t blood tra ve ls only in the dire ction of the he a rt. Cons triction a nd re la xa tion a llow the va s cula r s ys te m to dire ct blood to diffe re nt pa rts of the body, a nd to ma inta in blood pre s s ure whe n blood volume or ca rdia c output is de cre a s e d.
  • 109. Nota ble Ve s s e ls Re me mbe r… for e ve ry a rte ry ta king fre s h blood to the body, the re is a ve in to ca rry de oxyge na te d blood ba ck to the he a rt– jus t like on a nd off ra mps to the “ma jor highwa y!
  • 110.
  • 111. Fe line Thromboe mbolis m  a .k.a . a s a ddle thrombus  Cla s s ic pre s e nta tion is pos te rior pa re s is with we a k or a bs e nt puls e s in the re a r limbs ; foot pa ds a re pa le , a nd the toe na ils won’t ble e d whe n quicke d; the ga s trocne mius a nd tibia l mus cle s a re rock ha rd by 10-12 hrs pos t-clot  Aggre s s ive thrombolytic the ra py ma y be ins titute d if the clinicia n fe e ls the thrombus is re ce nt (2-4 hrs ) a nd the he a rt dis e a s e is ma na ge a ble but the prognos is is s till gua rde d
  • 112. Fe line Thromboe mbolis m (cont)  Mos t common s ite is a t the a ortic trifurca tion  Clinica l s igns de pe nd on the de gre e of he a rt dis e a s e a nd the s ite of thromboe mbolis m  It ma y be the firs t s ign of he a rt dis e a s e or s ome time s ca ts will s how s e ve re s igns of CHF