2. 2012
COMPANY PROFILE
ubio is a young, vibrant venture developing innovative solutions in medical, veterinary and food diagnostics. We leverage the latest and best technologies
from the fields of electronics, information technology, and biotechnology to create products and solutions that take hi-tech diagnostics to the mass-market.
ubio’s vision is Affordable, Accurate, Accessible Diagnostics for All.
ubio’s mission is to develop high-quality diagnostic products and make them accessible to
everyone at low cost, while creating value for its customers, employees, investors and partners.
ubio's product portfolio includes low-cost rapid tests for human, veterinary and food
diagnostics that make diagnostics affordable and accessible to patients, farmers and small
industries without any capital investment. We have also developed a new generation biochip
for clinical diagnostics market that will provide high quality test assays at significantly lower
price points.
Headquartered at Cochin, Kerala, India, ubio brings together key scientific and engineering
talent with experience in the cutting-edge of biotechnology, information technology and
electronics. Our technology leaders have proven expertise in product development and
management, and have made major contributions to software and biotechnology industries.
ubio was established in 2008 and the R&D laboratory and Manufacturing Facilities are located
at Kinfra Biotechnology Park, in Kerala. The GMP and ISO 13485 certified manufacturing
facility is approved by Indian Drug Regulatory authorities for the manufacture of IVDs. The R&D
facility of ubio is approved by Department of Scientific and Industrial Research, Government of
India.
GMP
CERTIFIED
ubio Business Profile
Veterinary and Food
Medical IVD Tests Contract Manufacture Contract Research
Tests
Companion Animal Lateral-flow tests Diagnostic tests
Infectious Diseases development
Tests
•ELISA, Lateral-flow,
LAT, PCR etc.
ELISA kits
Cancer and Cardiac Livestock Recombinant
Tests Diagnostics protein and
Latex Agglutination antibody
tests development
Drug of Abuse and Antibiotic and toxin
Raw Materials and
Fertility Products residues PCR tests uncut sheets
3. 2012
HUMAN
DIAGNOSTICS
The sensit tests are one-step Immuno-chromatographic assays for the
detection of antigen or antibodies in human Blood, serum, plasma or other body
fluids.
These rapid tests are inexpensive, disposable, membrane based RAPID
assays that provides visual evidence of the presence of an analyte in ONE STEP
clinical samples. The test uses colloidal gold conjugated antigen or POINT –OF-CARE
antibodies for visualisation of the results. The test kit consists of a
plastic cassettes containing a membrane strip. The
base substrate of the test is usually a nitrocellulose
membrane in which the test and control
Positive
antigen/antibodies are printed at specific locations. A
conjugate pad, a glass fibre sheet is attached to this
strip which contains dried gold conjugates. A sample
pad and absorbent pad are attached each ends, one act as sample Negative
wick and the other as sink.
The results are available within
When the sample is added to the sample pad, it will move 20 minutes.
Suitable for testing in low
towards the gold conjugate pad, re-hydrating the gold conjugate
resource setting.
and allowing the interaction of sample analyte with the conjugate. Portable, no need of equipment.
Results are comparable to ELISA
The complex of gold conjugate and analyte then moves onto the or other gold standards.
membrane strip and migrate towards the capture proteins printed Stable at room Temperature upto
2 years
on Test Line. The binding of gold conjugate complex will produce an
intense red line at the test line. A second line is also formed at the
control line region by the excess gold conjugate.
4. 2012
ubio SENSIT Rapid Tests
Tropical Diseases Malaria Products
Filariasis Antibody Test Malaria Antigen Test
Lateral flow Immunoassay for anti Wuchereria bancrofti These tests detect Plasmodium falciparum HRP antigen and/or
and Brugia malayi antibodies in human Blood, serum or Plasmodium vivax/Pan LDH antigen in Whole blood.
plasma. Malaria Pf HRP/Pan LDH Antigen test
Leishmaniasis Antibody Malaria Pf HRP/Pv LDH Antigen test
One step Immuno qualitative detection of antibodies to Malaria Pf HRP Antigen test
members of L. donovani complex in human serum.
Malaria Pan LDH Antigen test
Available as strips and cassette (whole blood).
Typhoid IgM Malaria Pv LDH Antigen test
Lateral flow assay for the specific detection of Salmonella
Typhi specific IgM antibodies in Human Blood, serum or Malaria Antibody Test
Plasma One step immuno-chromatographic assay for detection of
Brucella IgG Pv/Pf MSP and CSP specific antibodies of all isotypes (IgA, IgG
Lateral flow assay for detection of IgG response of and IgM) in Human blood, serum or Plasma
Brucella abortus, Brucella melitensis and brucella suis
infection in human. Enteric infections
Leptospira IgM Rota-Adeno Antigen test
IgM lateral flow assay for Human Leptospirosis. The test is Rapid immuno-chromatographic assay for detection of Rota
able to detect all serovars of Leptospira that causes and Adeno virus antigens in human stool in acute gastro
leptospirosis in humans. enteritis cases.
Human TB antigen tests H Pylori Antibody
H.pylori test is a rapid test for the qualitative detection of
MPT 64 Antigen test antibodies of all isotypes (IgG, IgM, IgA, etc.) specific
One step Immuno-chromatographic assy for the detection to Helicobacter pylori in human serum, plasma or whole blood
of MPT 64 Tb antigen in culture fluids and solid cultures.
H Pylori Antigen Test
TB LAM Test H.pylori Ag test is a rapid test for the qualitative detection
Mycobacterium tuberculosis and bovis specific of Helicobacter pylori antigen in human fecal specimen.
Lipoarabinomannan antigen detection test for culture
fluids. (also can be used for sputum testing) Fertility Hormones
Contract manufacturing and Loan licensing LH test
options. Home ovulation test for detection of Luteinising Hormone in
Tests are available is 1 test, 10 tests, 25, 30 and human urine.(25mIU/ml)
50 tests
OEM options hCG
Home urine pregnancy test for detection of human chorionic
Products are available as uncut sheets
Gonadotropins in Human urine. (10mIU/ml). Available as Card
and Strips
5. 2012
VETERINARY
DIAGNOSTICS
Animal Health Diagnostics ubio quickVET Rapid Tests
One step Immuno-chromatographic
Bovine Tests Canine Rapid Tests
assays Bovine TB Rapid Test
Bovine Brucella Rapid test Canine Parvovirus Antigen Test
Accurate Bovine TB-Brucella Combo Test Canine Distemper Virus antigen Test
Bovine FMD NSP Rapid test* Canine Corona Virus antigen test
High sensitive and good correlation Bovine Anaplasma Ab Rapid test. CPV-CCV Combo test
with other test method FMD antigen Rapid test.* Canine Adeno virus antigen test
Rota Virus Test Canine Ehrlichia Rapid test
Rabies virus antigen test Canine Lyme Antibody test
Anywhere
Bovine Viral Diarrhoea antigen test Canine Leptospira IgM test
Bovine pregnancy Rapid Test Canine Leishmania Antibody test
- Laboratory, Farm, Clinic, Home: Bovine Theilaria Rapid Test* Canine Brucella antibody test
No equipment needed Bovine Babesia rapid test.* Ag/Ab Rabies Antibody test
Bovine-Haemo-Protozoan Panel*
Simple Infectious Bovine Rhino-Tracheitis
Ab test
- One Step after collection a sample Bovine leukaemia Virus Ag Test
Bovine Leukaemia Test Ab test
Fast Neospora Antibody test
- Reliable Result within 10 min. Swine Tests Avian
Swine Brucella IBD antigen test
Swine FMD* NDV antigen test
Immediate
Echinococcus antibody test Marek’s Disease Antigen test
Porcine Corona Virus antigen test Infectious Bronchitis Antigen test
- Treatment and Avian Influenza antigen Test
PRRSV antigen Test
Management(vaccination, Classical Swine Fever Ag Test Avian antibody Tests:
quarantine) after identifying the TGEV antigen test. Avian Leukosis Virus Antigen
cause Pseodo-rabies(Ajeskey’s disease)
Antigen test
Rabies products Feline
Self
Rabies antigen tests Feline Toxoplasma Antibody test
Rabies FITC conjugate FeLV antigen Test
- Self testing by Pet owner or Rabies ELISA kit FIV antibody test
Farmer themselves FIV-FeLV Combo
Feline Parvo Rapid Test
Low cost Ovine Tests Fish/ Aquatic
Brucella ovis Rapid test WSSV lateral Flow*
- Time, Labor, Money saving Aeromonas caviae
Stenotrophomonas maltophilia
*under development
* coming soon
Positive
Negative
6. 2012
DRUG OF ABUSE*
A drug test is a technical analysis of a biological specimen – for example urine, hair,
blood, sweat, or oral fluid / saliva – to determine the presence or absence of specified
parent drugs or their metabolites. Major uses of drug testing are to detect the presence
of performance enhancing steroids in sport or for drugs prohibited by laws, such as
cannabis, cocaine and heroin. The drug abuse may lead to health problems, Social
problems, Physical dependence or psychological addiction
Product Target Compound Cut-Off levels(ng/ml)
AMP Amphetamine 1000 ng/ml
BAR Barbital 300 ng/ml
BZO Benzodiazepine 300 ng/ml
BUP Buprenorphine 10 ng/ml
COC Cocaine 300 ng/ml
KET Ketamine 300 ng/ml
MDMA Methylenedioxymethamphetamine 1000 mg/ml
MTD Methadone 300 ng/ml
MET Methamphetamine 1000 ng/ml
MOR Morphine 300 ng/ml
OXY Oxycodone 300 ng/ml
PCP Phencyclidine 25 ng/ml
PPX Propoxyphene 300 ng/ml
TCA Tricyclic Antidepressants 1000 ng/ml
THC Tetrahydrocannabinol 50 ng/ml
DOA-Multi Test Combination 2 or more tests
Human Blood stain Tests*
One step Immuno-chromatographic test to detect haemoglobin
residues in human blood and Blood stains
Semen test*
FORENSIC One step Immuno-chromatographic test to detect Prostate
Specific Antigen presence in human semen or semen stains
Note: these Products are available only on OEM and on Bulk orders.
7. 2012
RAW MATERIALS &
FOOD
DIAGNOSTIC
DIAGNOSTICS
REAGENTS
LATERAL FLOW RAW MATERIALS
Uncut Sheets(Master Sheets)
Uncut sheets of all the rapid tests are available. The standard size is 300X60mm. custom sizing and
membrane type is possible for a minimum order of 20 sheets.
Colloidal gold
Colloidal gold for various application like manufacture of rapid IVD kits, Cat. No Spec
Immuno electron microscopy application. UCG10000 10 liters
Available in sizes from 5nm, 10nm, 15, 20, 25, 30 and 40nms. UCG1000 1000ml
Supplied unconjugated with or without preservatives UCG100 100ml
UCG10 10ml
Colloidal silver
Colloidal silver for various application like manufacture of Lateral Cat. No Spec
Flow Assays UCS10000 10 liters
UCS1000 1000ml
UCS100 100ml
UCS10 10ml
Colloidal gold Conjugates
Colloidal gold conjugated with antibodies, usually at a rate of 10-30microgram per ml of gold. Available in
various ODs.
Anti-Human IgG
40nm colloidal gold conjugated to affinity purifies rabbit anti human IgG. Cat. No Spec
Supplied in Tris-Buffer with sodium azide preservative. UCG0101 1mg
UCG0102 5mg
Anti-Rabbit IgG
40nm colloidal gold conjugated to affinity purifies rabbit anti human IgG. Cat. No Spec
Supplied in Tris-Buffer with sodium azide preservative. UCG0201 1mg
UCG0202 5mg
Anti-Mouse IgG
40nm colloidal gold conjugated to affinity purifies rabbit anti human IgG. Cat. No Spec
Supplied in Tris-Buffer with sodium azide preservative. UCG0301 1mg
UCG0302 5mg
Anti-Goat IgG
40nm colloidal gold conjugated to affinity purifies rabbit anti human IgG. Cat. No Spec
Supplied in Tris-Buffer with sodium azide preservative. UCG0401 1mg
UCG0502 5mg
Anti-Bovine IgG
40nm colloidal gold conjugated to affinity purifies rabbit anti human IgG. Cat. No Spec
Supplied in Tris-Buffer with sodium azide preservative. UCG0501 1mg
UCG0602 5mg
Anti-BSA IgG
8. 2012
40nm colloidal gold conjugated to affinity purifies rabbit anti human IgG. Cat. No Spec
Supplied in Tris-Buffer with sodium azide preservative. UCG0601 1mg
UCG0602 5mg
Protein A
40nm colloidal gold conjugated to purified recombinant protein A(30µg/ml of Cat. No Spec
gold). Supplied in Tris-Buffer with sodium azide preservative. UCG0701 10mg
UCG0702 100mg
Protein G
40nm colloidal gold conjugated to purified recombinant protein G(30µg/ml of Cat. No Spec
gold). Supplied in Tris-Buffer with sodium azide preservative. UCG0801 1mg
UCG0902 10mg
UCG0903 100mg
Protein A/G
40nm colloidal gold conjugated to purified recombinant protein A/G(30µg/ml of Cat. No
gold). Supplied in Tris-Buffer with sodium azide preservative. UCG1001 10mg
UCG1002 100mg
Nano-particles
CdSe quantum dot Particle These are suitable for
CdS Quantum dot Particle quantum dot based
ZnO Quantum dot Particle diagnostics.
Fe3O4 Ferro-liquid /FePt Ferro-liquid
Magnetic beads suitable for magnetic bead separations
ELISA Reagents
TMB: Soluble
TMB - This aqueous non-hazardous liquid substrate for peroxidase consists of Tetramethylbenzidine Cat. No Spec
(TMB) plus dilute hydrogen peroxide in a single-reagent stabilized form. The reagent has been
specifically formulated for measuring peroxidase in ELISA systems which is stable for long-term
UER-CT-01 125ml
storage providing sensitivity greater than OPD. This reagent is available as a single component, UER-CT-02 500ml
ready-to-use reagent. When used in conjunction with our proprietary TMB Stop Buffer (TSB), the UER-CT-03 1000ml
resulting color product will not fade or darken for several hours. Our TMB products have built a
UER-CT-04 20Liters
reputation for robust performance, unparalleled stability and next to zero lot-to-lot variation. Each
TMB formulation can be specifically engineered to meet the needs of your specific assay
TMB Membrane
This liquid substrate for peroxidase consists of tetramethylbenzidine (TMB) plus dilute hydrogen Cat. No Spec
peroxide in a single-reagent stabilized form. The reagent has been specifically formulated for
measuring peroxidase in EIA systems. This reagent is stable for long-term storage, and provides
UER-CTP-01 125ml
sensitivity equal to, or greater than, that of other commercially available chromogens. UER-CTP-02 500ml
UER-CTP-03 1000ml
UER-CTP-04 10Liters
DAB One-Component Solution (3,3'-Diaminobenzidine)
his reagent produces a crisp, clean, very intense stain that is free of unwanted background. When in Cat. No Spec
the presence of peroxidase, DAB produces a brown precipitate that is insoluble in alcohol. Stained
slides may be mounted in any commercially available mounting media. This product is stable
UER-DAB-01 125ml
for 2-3 months. UER-DAB 02 500ml
UER-DAB-03 1000ml
TMB Stop buffer
ubio's Stop Buffer (TSB) offers a unique combination of acid that produces a more stable stopped Cat. No Spec
reaction product than other formulations of H2SO4 or HCL. Stopped reactions show increased
absorbance values of approximately two-fold over unstopped reactions with minimal drift for up to
UER-SBT-01 125ml
six hours depending on various conditions. UER-SBT-02 500ml
UER-SBT-03 1000ml
UER-SBT-04 20Liters
BCIP-NBT: soluble
5-Bromo-4-Chloro-3-Indolyl Phosphate/nitroblue Tetrazolium (BCIP/NBT) Solution. Is a widely used Cat. No Spec
chromogen for immunohistochemical and in-situ staining. This reagent is available as a single
component, ready to-use reagent. When in the presence of the Alkaline-Phosphatase enzyme,
UER-NBT-01 125ml
9. 2012
BCIP/NBT produces a purple precipitate that is soluble in alcohol. UER-NBT-02 500ml
UER-NBT-03 1000ml
UER-NBT-04 20Liters
ELISA Coat Stabiliser
Coating Stabilizer has been developed specifically for the stabilization of adsorbed or immobilized Cat. No Spec
proteins on microwell plates/strips. Coating Stabilizer maintains the conformation and activity of the
antibody or protein antigen portion of the dried immunoassay components. Product is filtered at 0.2
UER-CS-01 125ml
microns. UER-CS-02 500ml
Contents: Aqueous, protein-containing stabilizer and blocking solution in phosphate buffer for dried UER-CS-03 1000ml
protein components in immunoassays. Preservative: 0.02% Bromonitrodioxane, 0.02% 2-Methyl-4-
isothiazolin-3-one. pH 7.2 - 7.7
ELISA HRP stabiliser: Phosphate Buffered
This product has been developed to significantly increase the shelf life of diluted peroxidase labeled
proteins. Stability is increased at room temperature storage conditions in addition to 2- 8
centigrade. This product is subjected to 0.45 micron filtration, and contains no mercury or azide.
Cat. No Spec
This formulation insures consistently high levels of activity for both the enzyme and the antibody UER-HS-01 500ml
following long-term storage at final-use dilution. HRP Stabilizer greatly improves the signal to noise UER-HS-02 1000ml
ratios which increases the immunoassay sensitivity and offers cleaner assays.This product has been
chemically engineered to increase conjugate stability providing the customer a longer shelf life,
resistance to various shipping conditions & storage temperatures
and improved day to day assay precision.
Alk-Phos Stabilizing Diluent
This reagent is formulated specifically for Alkaline Phosphatase conjugates. The product insures
consistently high levels of activity for both the enzyme and the antibody following longterm storage Cat. No Spec
at final dilution. This product has been chemically engineered to increase conjugate stability
providing the customer a longer shelf life, resistance to various shipping conditions and storage UER-AS-01 500ml
temperatures. Alk-Phos Stabilizing Diluent is filtered at 0.2 um and reinforced with a non-mercury or UER-AS-02 1000ml
azide-free preservative. Inquire about custom vialing, labeling, kit assembly and drop shipping.
ELISA Developers KIT: HRP/AP Based
Complete "Do it Yourself" ELISA system. Contents:
The first ELISA system designed to deliver superior results to each and every research project, Blocking Buffer, HRP/AP
regardless of the level of technician expertise. Everything that is required to obtain outstanding Stabilizing Diluent, Binding Buffer,
results is included in one convenient package. Easy ELISA has been specifically developed to create Coating Stabilizer, TMB Soluble
an environment in which the researcher can be assured of consistent results with each project. All of Reagent, TMB Stop Buffer, Sample
the reagents contained in Easy ELISA are stable enough to ship at ambient temperature. Diluent, Wash Buffer (10X PBS)
Cat. No Spec
UER-1K 1 kit
Custom ELISA Reagents
All of the ELISA products are available in bulk quantities, including custom lot sizes up to 5000 liters. Ubio specializes in custom
manufacturing, vialing, labelling and packaging. E mail us for a quote
10. 2012
ubio's state-of-the-art manufacturing facility at
Kalamassery, Cochin, India can manufacture
Contract conventional diagnostic kits in addition to our
patented biochip devices. We offer contract
manufacture of all kinds of Rapid and ELISA kits on
OEM terms.
Manufacture Being a start-up, ubio is nimble and provides short
turn-around times for manufacture and a very
responsive customer-care. We can manufacture test kits even in small batches, which makes us the right
partner for firms who want to test their brand in the
market before installing a complete manufacturing
facility. ubio is the right manufacturing
For further details on our OEM service write partner for you, especially if you
to: contact@ubio.in ubio can manufacture and supply complete test kits need:
with all components including plastic containers,
droppers, printed packaging, outer cartons etc. which Variable-volume manufacture
leaves you time and money to concentrate on product
marketing
Quick introduction of new
product into the market without
initial capital investment
Protection for your investment
against market fluctuations,
ubio has full capability for the development of Immunoassays, Molecular diagnostics and Microarray obsolescence, and competition
chips for various applications. We can take up the
product development even from the development of Quick scale-up to peak demand
Assay Development at ubio
basic raw materials like recombinant protein/peptides without capital investment
or monoclonal antibodies.
Low turnaround time
Validated Technology Platforms, Our platform technologies include.
Product development using Lateral flow assays
technologies already
commercialised by ubio.
Flow through Assays
Particle Conjugation Technologies
Contract
Enzyme Linked Immunosorbant Assays
Stable Products, and flexibility in
optimisation.
Line probe and Dot probe assays
Low Density Microarrays.
Assay
Clinical validation in actual PCR-lateral Flows.
samples.
100% confidentiality.
Bead Based Assays.
Fluorescence based assays.
Development
Quantitative and semi-quantitative Assays.
Scaling up and pilot manufacturing Small molecules assays
facility
Option for further contract
manufacture
Full Technology Transfer For Further Details on our Research
Continuous support from ubio Services, Write to: to-contact@ubio.in
Team.
11. 2012
ORDERING
INFORMATION
Contact Information
ubio Biotechnology Systems Pvt Ltd,
XII-111-E/F, Technology Incubation Centre
KINFRA Hi-Tech Park, Kalamassery
Cochin, Kerala, India 683503
Tel. No: +91-484-2532966
E mail: contact@ubio.in
Web: www.ubio.in
Pricing
The prices will be quoted either in INR or USD. Quantity discounts are available for Bulk orders.
Cancellation
The orders can be cancelled within 2 days after placing the purchase order.
Payment Terms
All orders are prepaid unless prior credit arrangements have been made with us. All orders are FOB, Cochin
and freight charges and Insurance have to be borne by the customer. Special shipping charges can be
negotiated with our shipping agent for bulk orders. The payment can be made by Wire Transfer, Letter of
Credit or Bank Draft.
Our Bank Details are as follows.
For customers in India For Overseas Customers
BANK NAME AND ADDRESS : STATE BANK OF INDIA, M. BANK NAME AND ADDRESS: STANDARD
G. ROAD BRANCH, ERNAKULAM, KERALA CHARTERED BANK, ERNAKULAM BRANCH,
ACCOUNT NAME: UBIO BIOTECHNOLOGY SYSTEMS PVT. RAVIPURAM, ERNAKULAM, KERALA, INDIA.
LTD. BENEFICIARY NAME: UBIO BIOTECHNOLOGY
IFSC CODE: SBIN0003539 SYSTEMS PVT LTD
ACCOUNT NO: 30641422205 SWIFT CODE: SCBLINBBCON
BENEFICIARY ADDRESS: XII-111-E/F, TECHNOLOGY ACCOUNT NO.: 43405060909
INCUBATION CENTRE, KINFRA HI-TECH PARK, BENEFICIARY ADDRESS: XII-111-E/F,
KALAMASSERY, COCHIN, KERALA, INDIA 683503 TECHNOLOGY INCUBATION CENTRE, KINFRA HI-
TECH PARK, KALAMASSERY, COCHIN, KERALA,
INDIA 683503
Shipping
The shipments are made on FCA basis unless otherwise specified. Custom Packaging is possible on request.
Returned Goods Policy
No Return shall be accepted without prior approval from ubio.
12. 2012
ubio Biotechnology Systems Pvt Ltd
XII-111-E/F, Technology Incubation Centre, KINFRA Hi-Tech Park, Kalamassery, Cochin, Kerala, India , 683503
Ph:,+91-484-2532966/+91-9744122269, E mail: contact@ubio.in , www.ubio.in