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                                                                                                                                                                                                                           B
   lOCAtION                                                                        fEES AND rEgIStrAtION
Jacobs	University	Bremen	gGmbH                                                  GDCh-member	                     e	990,–
Campus	Ring	1                                                                   Non-member	                    e	1.230,–
28759	Bremen                                                                                                                                                                  Gesellschaft Deutscher Chemiker
                                                                                Rates	 include	 instruction	 material	 and	 GDCh-Certificate,	 excluding	 accom-
                                                                                modation	and	catering.	They	are	not	liable	to	the	value	added	tax	(tax	exemp-




                                                                                                                                                                                                                           I
   hOw tO gEt thErE
                                                                                tion	additional	§	4	Nr.	21a)	bb)	UStG.)
The	participants	will	receive	a	detailed	journey	description	to	the	location	   Please	register	via	Internet	or	by	mail	at	the	office	of	GDCh	until		
at	the	deadline.                                                                March	29,	2010	(deadline):




                                                                                                                                                                                                                           O
   ACCOmmODAtION                                                                GESELLSCHAFT	DEUTSCHER	CHEMIKER	e.V.	(GDCh)	
                                                                                German	Chemical	Society
The	following	hotels	are	suggested	for	accomodation:                            Continuing	Education		
                                                                                P.O.	Box	90	04	40                                                                        Downstream Bioprocessing
Accomodation	on	Jacobs	University	Bremen	Campus	                                60444	Frankfurt/Main	
Campus	Ring	1	                                                                  Germany                                                                                  A	practical	approach	to	downstream	Bioprocess		




                                                                                                                                                                                                                           S
28759	Bremen                                                                                                                                                             design,	Scale-up,	and	Implementation	
                                                                                phone:		    +49	69	7917-364/-291
phone:	+49	421	200-3239/3531,	fax:	+49	421	200-3660
                                                                                fax:		      +49	69	7917-475
e-mail:	n.nentwig@jacobs-university.de,	web:	www.jacobs-university.de
                                                                                e-mail:		   fb@gdch.de
                                                                                                                                                                         Prof.	Dr.	Marcelo	Fernández-Lahore	
                                                                                web:		      www.gdch.de/fortbildung                                                      Dr.	Sonja	Diercks-Horn
Strandlust	Vegesack	GmbH,	Rohrstraße	11,	28757	Bremen
phone:	+49	421	6609-0,	fax:	+49	421	6609-111                                    Executive	director:	Professor	Dr.	Wolfram	Koch




                                                                                                                                                                                                                           C
e-mail:	info@strandlust.de,	web:	www.strandlust.de                              Registered	charity	no:	VR	4453	·	Registergericht	Frankfurt	am	Main

                                                                                With	your	registration	you	agree	to	confirm	with	the	AGB	of	the	GDCh.		                    	 Bioseparation	Science
Atlantic	Hotel	Vegesack,	Sagerstraße	20,	28757	Bremen-Vegesack
                                                                                The	AGB	regulations	can	be	found	on	the	Internet	under		
phone:	+49	421	6605-0,	fax:	+49	421	664774
                                                                                www.gdch.de/teilnahme.                                                                     	 Innovative	Technologies
e-mail:	info@atlantic-hotel-vegesack.de,	web:	atlantic-hotel-vegesack.de




                                                                                                                                                                                                                           I
                                                                                After	receipt	of	your	registration	you	will	receive	a	registration	confirmation/           	 Product	Recovery
For	further	hotels	please	contact:                                              invoice	for	your	registration	(with	online	registrations,	please	ensure	that	you	
Bremer	Touristik-Zentrale                                                       print	out	the	last	page	of	your	registration)	upon	completion	of	registration	             	 High	Resolution	Purification
Gesellschaft	für	Marketing	und	Service	mbH                                      you	 will	 receive	 detailed	 information	 with	 regards	 to	 the	 meeting.	 Should	
Findorffstraße	105                                                              more	than	2	employees	from	your	company	participate	in	the	meeting,	we	                    	 Bioprocess	Economics




                                                                                                                                                                                                                           E
28215	Bremen                                                                    will	offer	a	10%	reduction	from	the	3rd	employee	onwards.
phone:		 +49	18	05	10	10	30	or	+49	421	30	800	10                                Cancellations	 received	 six	 weeks	 prior	 to	 the	 registration	 deadline	 will	 be	
fax:		     +49	421	30	800-30                                                    cancelled	free	of	charge.	Cancellations	received	within	six	weeks	of	this	date	
web:		     www.bremen-tourismus.de                                              will	be	charged	e	50	processing	fee.	There	will	be	no	refund	for	cancella-
                                                                                tions	received	after	the	deadline	the	participant	will	be	required	to	pay	the	




                                                                                                                                                                                                                           N
                                                                                full	registration	fee.	All	cancellations	must	be	received	in	writing.	Substitute	
                                                                                participants	can	be	named	without	additional	costs.
                                                                                If	the	meeting	is	cancelled	by	the	GDCh	for	whatever	reason,	paid	fees	will	
                                                                                be	refunded	in	full.	Further	recourse	is	excluded.

                                                                                   INfOrmAtION ABOut furthEr gDCh-COurSES




                                                                                                                                                                                                                           C
                                                                                907/10	     Chemical	Development	and	Scale-Up	in	the	Fine	Chemical	
                                                                                	           and	Pharmaceutical	Industries
                                                                                	           Dr.	Will	Watson/Dr.	Derek	Robinson
                                                                                	           November	23	–	25,	2010	·	Frankfurt/Main	




                                                                                                                                                                                                                           E
                                                                                                                                                                         174/10

                                                                                                                                                                         April 26 – 28, 2010 · Bremen




                                                                                                                                                                                                                           S
                                                                                                www.gdch.de/fortbildung
OBjECtIvES                                                                             prOgrAmmE*                                                                   OrgANISEr
 Participating	in	this	course	will	assure	that:	                                          	 	 Monday,	April	26,	2010                                                                      Prof.	Dr.	Marcelo	Fernández-Lahore
 •	 You	gain	insight	of	key	aspects	of	biotech	manufacturing                                                                                                                              Jacobs	University	Bremen	gGmbH	
                                                                                      	     	 Basic	Concepts	and	Experiments
 •	 You	understand	how	to	separate	bioproducts
                                                                                      	 9.00	 Introduction	to	Downstream	Bioprocessing
 •	 You	learn	which	approaches	are	best	suitable	to	exert	such	separation
                                                                                      	 9.30	 Primary	Recovery	(Cell	disruption,	Solid-liquid	separation,		
 •	 You	gain	practical	skills	in	the	laboratory
                                                                                      	     	 Extractive	recovery,	Membrane	operation)	
 •	 You	apply	software	tools	to	design	and	optimise	bioprocesses                                                                                                                          	
                                                                                      10.30	 Coffee	break
 •	 You	are	able	to	implement	all	of	the	above	into	your	current	project
                                                                                      10.45	 Purification	and	Chromatography	(Chromatography	modes	and		            Marcelo	 Fernández-Lahore	 is	 currently	 Professor	 for	 Biochemical	 Engi-
 Moreover,	 innovative	 approaches	 to	 bioproduct	 downstreaming	 will	              	    	 current	platforms)                                                     neering	at	Jacobs	University	(Bremen,	Germany)	and	Project	manager	of	
 be	 presented	 in	 the	 context	 provided	 by	 established	 technologies	 and	 	     11.30	   Innovative	and	Up-Coming	Approaches	(Biomaterial	science,		          EU	 funded	 R&D.	 He	 was	 born	 in	 Buenos	 Aires	 (RA)	 in	 1962,	 where	 he	
 industrial	practices.                                                                	    	   Molecular	bioseparation,	Thermodynamics)	(Novel	adsorbents	and		     obtained	a	Diploma	in	Biochemistry	(1986)	and	a	Doctoral	Degree	in	In-
                                                                                      	    	   affinity	ligands),	other	approaches	(selective	precipitation	and		   dustrial	Microbiology	and	Biotechnology	(1995).	He	spent	2	years	of	post-
                                                                                      	    	   crystallization)                                                     doctoral	research	with	Maria-Regina	Kula	at	the	University	of	Düsseldorf	
   tOpICS                                                                                                                                                           (Research	Centre	Jülich)	before	he	took	up	a	Junior	Group	Leader	position	
                                                                                      12.30	 Lunch
                                                                                                                                                                    at	CONICET	(Argentina).	He	is	also	Adjunct	Professor	for	Biotechnology	
 Emphases	in	this	course	are:                                                         14.00	 Laboratory	Experiments	I	(Extraction)                                  and	Food	Engineering	at	the	Monterrey	Institute	of	Technology	(Monterrey,	
 •	 Various	strategies	and	technological	platforms	for	bioproduct	separa-             15.30	 Coffee	break                                                           Mexico).		
    tion	and	purification	will	be	presented	and	discussed
                                                                                      15.45	 Laboratory	Experiments	I	(Extraction)
 •	 Exposure	to	the	fundamentals	of	both	traditional	and	modern	tech-                                                                                                                     Dr.	Sonja	Diercks-Horn
    niques	utilised	during	downstream	bioprocessing                                   18.00	 Expected	end	of	1st	Day	             							
                                                                                                                                                                                          Jacobs	University	Bremen	gGmbH
 •	 Understanding	of	these	methods	and	unit	operation	per	se	but	also	                18.30	 	Dinner
    in	the	context	of	the	whole	purification	sequence                                 	    							

 •	 Covering	of	key	issues	related	to	the	dovetailing	of	fermentation/cell	               	 	 Tuesday,	April	27,	2010
    cultivation	with	early	recovery	steps                                             	     	 Process	design	and	Simulation	 							
 •	 Emphases	of	process	analytics,	product	quality,	and	processing	cost	              	 9.00	 Introduction	to	BioPro	Designer	Software
    aspects
                                                                                      10.00	 Analysis	of	case	examples                                              Sonja	Diercks-Horn	was	born	in	1979	in	Bremen	(Germany)	and	studied	
                                                                                                                                                                    technical	 and	 applied	 Biology	 at	 the	 Hochschule	 Bremen,	 University	 of	
                                                                                      10.30	 Coffee	break
   tArgEt grOupS                                                                                                                                                    Applied	Sciences	(Bremen,	Germany).	In	2007,	she	obtained	her	PhD	un-
                                                                                      10.45	 Analysis	of	case	examples                                              der	the	supervision	of	Linda	K.	Medlin	(Alfred	Wegener	Institute	for	Polar	
This	short	course	is	offered	to	(bio)	chemical	engineers,	(protein)	chemists,	        12.30	 Lunch                                                                  and	Marine	Research,	Bremerhaven,	Germany)	and	continued	working	as	
and	other	scientists	within	the	Life	Science	industry	who	are	involved	in	the	                                                                                      a	postdoctoral	scientist	for	the	GKSS	Research	Centre	(Geesthacht,	Ger-
                                                                                      14.00	 Laboratory	Experiments	II	(Adsorption)
design	and	implementation	of	the	downstream	purification	of	bioproducts.	                                                                                           many).	Late	2008,	she	joined	the	Downstream	Processing	group	(School	
The	 course	 is	 equally	 suitable	 for	 managers	 who	 are	 responsible	 for	 bio-   15.30	 Coffee	break                                                           of	Engineering	and	Science)	at	Jacobs	University	Bremen.
processing	 areas	 and	 for	 practitioners/academicians	 otherwise	 interested	       15.45	 Laboratory	Experiments	II	(Adsorption)
in	the	subject.                                                                       18.00	 Expected	end	of	2nd	Day                                                   lECturErS
                                                                                      	    							
   prEvIOuS kNOwlEDgE                                                                                                                                               Known	specialists	from	the	American	and	European	industry,	as	well	as	
                                                                                          	 	 Wednesday,	April	28,	2010                                             representatives	from	academia	will	contribute	to	the	programme
Fundamental	knowlegde	in	Biochemistry	or	Biotechnology	or	Bioprocessing	              	     	 Quality	Control	and	Process	Validation
would	be	of	advantage.	                                                                                                                                                tEAChINg mEthODS
                                                                                      	 9.00	 Quality	manufacturing	and	product	formulation
   pArtICIpANtS                                                                       10.00	 Process	validation	and	Sanitation,	Process	Economics                   Lectures;	 Experiments	 in	 the	 laboratory;	 Case	 studies,	 Computer	 simu-
                                                                                                                                                                    lation
max.	20	participants                                                                  10.30	 Coffee	break
                                                                                      11.00	 Course	Evaluation	and	Final	Remarks                                       INStruCtION mAtErIAl
                                                                                      12.00	 Expected	end	of	the	course                                             Course	materials	will	be	provided.	



                                                                                                                 * Subject to modification


                                                                                                     www.gdch.de/fortbildung

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A Practical Approach to Downstream Processing

  • 1. W NE B lOCAtION fEES AND rEgIStrAtION Jacobs University Bremen gGmbH GDCh-member e 990,– Campus Ring 1 Non-member e 1.230,– 28759 Bremen Gesellschaft Deutscher Chemiker Rates include instruction material and GDCh-Certificate, excluding accom- modation and catering. They are not liable to the value added tax (tax exemp- I hOw tO gEt thErE tion additional § 4 Nr. 21a) bb) UStG.) The participants will receive a detailed journey description to the location Please register via Internet or by mail at the office of GDCh until at the deadline. March 29, 2010 (deadline): O ACCOmmODAtION GESELLSCHAFT DEUTSCHER CHEMIKER e.V. (GDCh) German Chemical Society The following hotels are suggested for accomodation: Continuing Education P.O. Box 90 04 40 Downstream Bioprocessing Accomodation on Jacobs University Bremen Campus 60444 Frankfurt/Main Campus Ring 1 Germany A practical approach to downstream Bioprocess S 28759 Bremen design, Scale-up, and Implementation phone: +49 69 7917-364/-291 phone: +49 421 200-3239/3531, fax: +49 421 200-3660 fax: +49 69 7917-475 e-mail: n.nentwig@jacobs-university.de, web: www.jacobs-university.de e-mail: fb@gdch.de Prof. Dr. Marcelo Fernández-Lahore web: www.gdch.de/fortbildung Dr. Sonja Diercks-Horn Strandlust Vegesack GmbH, Rohrstraße 11, 28757 Bremen phone: +49 421 6609-0, fax: +49 421 6609-111 Executive director: Professor Dr. Wolfram Koch C e-mail: info@strandlust.de, web: www.strandlust.de Registered charity no: VR 4453 · Registergericht Frankfurt am Main With your registration you agree to confirm with the AGB of the GDCh. Bioseparation Science Atlantic Hotel Vegesack, Sagerstraße 20, 28757 Bremen-Vegesack The AGB regulations can be found on the Internet under phone: +49 421 6605-0, fax: +49 421 664774 www.gdch.de/teilnahme. Innovative Technologies e-mail: info@atlantic-hotel-vegesack.de, web: atlantic-hotel-vegesack.de I After receipt of your registration you will receive a registration confirmation/ Product Recovery For further hotels please contact: invoice for your registration (with online registrations, please ensure that you Bremer Touristik-Zentrale print out the last page of your registration) upon completion of registration High Resolution Purification Gesellschaft für Marketing und Service mbH you will receive detailed information with regards to the meeting. Should Findorffstraße 105 more than 2 employees from your company participate in the meeting, we Bioprocess Economics E 28215 Bremen will offer a 10% reduction from the 3rd employee onwards. phone: +49 18 05 10 10 30 or +49 421 30 800 10 Cancellations received six weeks prior to the registration deadline will be fax: +49 421 30 800-30 cancelled free of charge. Cancellations received within six weeks of this date web: www.bremen-tourismus.de will be charged e 50 processing fee. There will be no refund for cancella- tions received after the deadline the participant will be required to pay the N full registration fee. All cancellations must be received in writing. Substitute participants can be named without additional costs. If the meeting is cancelled by the GDCh for whatever reason, paid fees will be refunded in full. Further recourse is excluded. INfOrmAtION ABOut furthEr gDCh-COurSES C 907/10 Chemical Development and Scale-Up in the Fine Chemical and Pharmaceutical Industries Dr. Will Watson/Dr. Derek Robinson November 23 – 25, 2010 · Frankfurt/Main E 174/10 April 26 – 28, 2010 · Bremen S www.gdch.de/fortbildung
  • 2. OBjECtIvES prOgrAmmE* OrgANISEr Participating in this course will assure that: Monday, April 26, 2010 Prof. Dr. Marcelo Fernández-Lahore • You gain insight of key aspects of biotech manufacturing Jacobs University Bremen gGmbH Basic Concepts and Experiments • You understand how to separate bioproducts 9.00 Introduction to Downstream Bioprocessing • You learn which approaches are best suitable to exert such separation 9.30 Primary Recovery (Cell disruption, Solid-liquid separation, • You gain practical skills in the laboratory Extractive recovery, Membrane operation) • You apply software tools to design and optimise bioprocesses 10.30 Coffee break • You are able to implement all of the above into your current project 10.45 Purification and Chromatography (Chromatography modes and Marcelo Fernández-Lahore is currently Professor for Biochemical Engi- Moreover, innovative approaches to bioproduct downstreaming will current platforms) neering at Jacobs University (Bremen, Germany) and Project manager of be presented in the context provided by established technologies and 11.30 Innovative and Up-Coming Approaches (Biomaterial science, EU funded R&D. He was born in Buenos Aires (RA) in 1962, where he industrial practices. Molecular bioseparation, Thermodynamics) (Novel adsorbents and obtained a Diploma in Biochemistry (1986) and a Doctoral Degree in In- affinity ligands), other approaches (selective precipitation and dustrial Microbiology and Biotechnology (1995). He spent 2 years of post- crystallization) doctoral research with Maria-Regina Kula at the University of Düsseldorf tOpICS (Research Centre Jülich) before he took up a Junior Group Leader position 12.30 Lunch at CONICET (Argentina). He is also Adjunct Professor for Biotechnology Emphases in this course are: 14.00 Laboratory Experiments I (Extraction) and Food Engineering at the Monterrey Institute of Technology (Monterrey, • Various strategies and technological platforms for bioproduct separa- 15.30 Coffee break Mexico). tion and purification will be presented and discussed 15.45 Laboratory Experiments I (Extraction) • Exposure to the fundamentals of both traditional and modern tech- Dr. Sonja Diercks-Horn niques utilised during downstream bioprocessing 18.00 Expected end of 1st Day Jacobs University Bremen gGmbH • Understanding of these methods and unit operation per se but also 18.30 Dinner in the context of the whole purification sequence • Covering of key issues related to the dovetailing of fermentation/cell Tuesday, April 27, 2010 cultivation with early recovery steps Process design and Simulation • Emphases of process analytics, product quality, and processing cost 9.00 Introduction to BioPro Designer Software aspects 10.00 Analysis of case examples Sonja Diercks-Horn was born in 1979 in Bremen (Germany) and studied technical and applied Biology at the Hochschule Bremen, University of 10.30 Coffee break tArgEt grOupS Applied Sciences (Bremen, Germany). In 2007, she obtained her PhD un- 10.45 Analysis of case examples der the supervision of Linda K. Medlin (Alfred Wegener Institute for Polar This short course is offered to (bio) chemical engineers, (protein) chemists, 12.30 Lunch and Marine Research, Bremerhaven, Germany) and continued working as and other scientists within the Life Science industry who are involved in the a postdoctoral scientist for the GKSS Research Centre (Geesthacht, Ger- 14.00 Laboratory Experiments II (Adsorption) design and implementation of the downstream purification of bioproducts. many). Late 2008, she joined the Downstream Processing group (School The course is equally suitable for managers who are responsible for bio- 15.30 Coffee break of Engineering and Science) at Jacobs University Bremen. processing areas and for practitioners/academicians otherwise interested 15.45 Laboratory Experiments II (Adsorption) in the subject. 18.00 Expected end of 2nd Day lECturErS prEvIOuS kNOwlEDgE Known specialists from the American and European industry, as well as Wednesday, April 28, 2010 representatives from academia will contribute to the programme Fundamental knowlegde in Biochemistry or Biotechnology or Bioprocessing Quality Control and Process Validation would be of advantage. tEAChINg mEthODS 9.00 Quality manufacturing and product formulation pArtICIpANtS 10.00 Process validation and Sanitation, Process Economics Lectures; Experiments in the laboratory; Case studies, Computer simu- lation max. 20 participants 10.30 Coffee break 11.00 Course Evaluation and Final Remarks INStruCtION mAtErIAl 12.00 Expected end of the course Course materials will be provided. * Subject to modification www.gdch.de/fortbildung