7. Método
Revisão de literatura em bases de dados e livros.
Imunossenescência; involução tímica; imunidade
adaptativa; inata; inflammaging.
Descritores
12. T CD8+ CD27- CD28- /CD45+
CMV
CD56
Anergia
Resistência à
apoptose
(LOONEY et al., 1999; MCLEOD, 2001; PAWELEC et al., 2006; WENG, AKBAR e GORONZY, 2009)
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BEERMAN, I. et al. Functionally distinct hematopoietic stem cells modulate hematopoietic lineage potential during aging by a
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BRUBAKER, A. L. et al. Reduced neutrophil chemotaxis and infiltration contributes to delayed resolution of cutaneous wound
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BUTCHER, S. K. et al. Neutrophil Ageing and Immunosenescence. , 4, 41-55. NeuroImmune Biology, v. 4, p. 41-55, 2004.
DE MARTINIS, M. et al. Inflamm-ageing and lifelong antigenic load as major determinants of ageing rate and longevity. FEBS
letters, v. 579, n. 10, p. 2035-2039, 2005.
DOWLING, M. R.; HODGKIN, P. D. Why does the thymus involute? A selection-based hypothesis. Trends in Immunology, v.
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FRANCESCHI, C. et al. The network and the remodeling theories of aging: historical background and new perspectives.
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