Situs Inversus totalis is a genetic condition that causes the organs in the chest and abdomen to be positioned in a mirror image from their normal positions. This gives an idea about the Signs/Symptom, Diagnosis, Treatment and Special concerns of the syndrome.

1. Something wrong ?

2. Situs Inversus totalis
Aziza Al-amri

3. Outlines ..
 Definition
 Prevalence
 Types
 Possible Causes
 Signs and Symptom
 Diagnosis
 Treatment
 Special concerns

4. Definition
Situs Inversus totalis is a genetic condition that causes the
organs in the chest and abdomen to be positioned in a
mirror image from their normal positions.
• Eg. In the abdominal cavity, the liver is positioned on the
left side instead of the right, and the stomach is on the
right side instead of the left.

7. Prevalence
 Situs inversus totalis has been estimated to occur
once in about (8-10,000) births.
 20% of patients with situs inversus have a rare
abnormal condition called Kartagener's syndrome.
 Only 50% of patients with Kartagener syndrome
have situs inversus

8. Types
Situs inversus totalis
Situs inversus thoracalis
Situs inversus abdominalis
All organs are transposed in a mirror image of the normal positioning
Only lungs and heart
Liver, stomach and spleen

9. Situs inversus totalis
LevocardiaDextrocardia

10. Possible Cause !
• Mutation in the coding region of
DNAH11(Bartoloni et al., 2002).
• Developmental stage of an embryo !

11. Signs and Symptom
• No medical symptoms or complications .
• 3-5% have functional heart defect
• 25% have an underlying condition called primary
ciliary dyskinesia (PCD)

12. Diagnosis
It can be detected using
• X-ray
• CT
• MRI
• Ultrasonography
A doctor/RT may suspect
• Heartbeat ?

13. Treatment
• No cure for situs inversus.
• If other complications are present, the
symptoms will be treated accordingly.

14. Special concerns !
• Failure to recognize situs inversus ?
• Attention to the left and right sides of the patient and
the left and right labeling of images .
• Organ donation !

15. At the end ..