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Tahitian Noni® Original Bioactive Increases Antioxidant
Status and Improves Endurance in Highly Trained Athletes.
Palu et al. 2008. Journal of Medicinal Plant Research, 2 (7),
154-158.
In a placebo-controlled clinical trial involving 40 highly
trained athletes, Tahitian Noni® Original Bioactive (TNJ)
was shown to increase endurance by 21%, while it increased
antioxidant status of the blood by 25%.
Tahitian Noni® Original Bioactive Health Effects on Cervical
Spondylosis.
Akinbo et al. (2006). Nigerian Journal of Health and Bio-
medical Sciences, 5, 6-11.
A one month clinical trial with 90 cervical spondylosis
patients found that drinking 30 mL of Tahitian Noni®
Original Bioactive (TNJ) per day improved range of move-
ment and pain in addition to further increased benefits from
a combination of TNJ and standard therapy.
Tahitian Noni® Original Bioactive Does Not Contain Ath-
letic Banned Substances.
Palu et al. (2008). Journal of Medicinal Plants Research 2(7):
154-158.
A pilot study with 6 people drinking Tahitian Noni®
Original Bioactive revealed the absence of all performance-
enhancing drugs and substances banned by the World Anti
Doping Association.
Tahitian Noni® Original Bioactive Has DNA Protection Ef-
fects.
Wang et al. (2007). AACR Annual Meeting April 14-18. Los
Angeles, CA
Drinking 1 or 4 ounces of Tahitian Noni® Original Bioactive
(TNJ) was shown to reduced the amount of MDA caused
DNA damage by 53% in a double-blind, placebo-controlled,
one month clinical trial involving 203 current heavy smok-
ers.
Tahitian Noni® Original Bioactive has a positive effect on
postmenopausal women.
Langford et al. (2004). The Journal of Alternative and Com-
plementary Medicine, 10, 737-742.
A three month, placebo controlled, pilot study, with 8 post-
menopausal women showed that drinking 4 ounces of
Tahitian Noni® Original Bioactive improved mood, energy,
attenuated hearing loss, and showed evidence of potential
anti-osteoporosis effect.
Tahitian Noni® Original Bioactive Is Safe for Human Con-
sumption.
The EFSA Journal 2006, 376: 1-12.
The European Food Safety Authority reports, “it is unlikely
that consumption of noni juice, at the observed levels of in-
take, induces adverse human liver effects.”
Tahitian Noni® Original Bioactive Not a Significant Source
of Potassium.
A case report stated that the potassium content of noni juice
was 56.3 mEq/L, or 65 mg/ounce, and may be a “surrepti-
tious” source of potassium for patients with renal disease.
(Mueller et al. Am J. Kidney Dis. 2000 35: 330–2). Mueller
(USA Today, March 28, 2000) clarified his research, stating
he did not analyze TNJ (Tahitian Noni® Original Bioac-
tive), but rather a different brand of noni juice and that the
amount of potassium was only “as much as you’d get in
2 inches of banana.”
Tahitian Noni® Original Bioactive Not a Significant Source
of Potassium.
West et al. (2006). International Journal of Food Sciences
and Nutrition, 57(7/8), 556-558..
Potassium content of Tahitian Noni® Original Bioactive is
30-50 mg per 1 ounce serving. This is a minor source when
compared with bananas, yogurt, and other significant di-
etary sources of potassium.
Tahitian Noni® Original Bioactive Does Not Contain
Vitamin K.
Palu ‘AK et al., Am J Hematol 2005 79: 79-82.
Vitamin K has not been detected in Tahitian Noni® Original
Bioactive and in noni fruits from Tahiti.
*Source: USDA Nutrient Database for Standard Reference.
Noni Fruits from Tahiti Contains Iridoids
Deng et al. (2010). Phytochemical Analysis. DOI: 10.1002/
pca.1246
Chemical research has revealed that iridoids are the major
bioactive phytochemicals in noni fruit from Tahiti. The pres-
ence of iridoids and their wide range of biological activities
explain the health benefits of Tahitian Noni® Original Bio-
active.
Shown in Product Identification Guide, page 319
TAHITIAN NONI® NONI LEAF SERUM
DESCRIPTION
In an exclusive process known only to Tahitian Noni Inter-
national, we’ve extracted the juice of the long-treasured
noni leaf and made it into a soothing balm. Especially for
skin that’s been exposed to the elements, this serum will
condition and revitalize irritated, wind-chaffed, or sun-
burned skin with lasting relief.
Ingredients: TAHITIAN NONI® Exclusive Noni Leaf For-
mula [Purified Water, Morinda citrifolia (Noni) Leaf Juice,
Morinda citrifolia (Noni) Leaf Extract, Vanilla tahitensis
(Tahitian Vanilla) Fruit Extract], Pentylene Glycol,
Propylene Glycol, SD Alcohol 40-B, PEG-400 Laurate and
Laureth-4, Sodium Dehydroacetate, Disodium EDTA,
Phenoxyethanol, Fragrance, Acrylates/C10-30 Alkyl Acry-
late Crosspolymer, Potassium Hydroxide.
Suggested Use: Smooth over irritated skin as needed.
Storage: Keep tightly closed in a dry place; do not expose
to excessive heat.
HOW SUPPLIED
1, 3 and 6 packs of cream, 1 oz/30 ml Packaged for Tahitian
Noni International, a subsidiary of Morinda, Inc. Provo, UT
84604. USA.
REFERENCES
Tahitian Noni® Leaf Extract Topical Usage Promotes
Wound Healing.
Palu et al, (2010). Phytotherapy Research. DOI: 10.1002/
ptr.3150.
A noni leaf ethanolic extract demonstrated significant
wound healing effects in the mouse cutaneous assay by dou-
bling the wound closure rate with 5.4 CT50.
Tahitian Noni® Leaf Extract Offers Skin Protection.
West et al. (2009). Journal of Natural Medicines, 63 (3), 351-
354.
A clinical trial involving 25 people showed that noni leaf ex-
tracts protected the skin against ultraviolet (UV) induced
redness and swelling by approximately 350%.
Noni Leaf Extracts Taken Internally Promotes Wound Heal-
ing.
Nayak BS et al. (2007). eCAM, 1-6.
The ethanolic extract from the noni leaf significantly en-
hanced wound contraction, decreased epithilialization time,
and increased hydorxyproline, suggesting that noni leaf ex-
tract has wound healing properties.
Noni Leaf Preparation Has Tonic and Antiseptic Effect.
Mannetje L. Morinda citrifolia L. in: Plant-Resources of
South-East Asia (Edit.: E. Westphal, P. and C. M. Jansen).
Pudoc Wageningen 1989, p. 185-187.
A noni leaf preparation is used as a tonic and antiseptic.
Leaves are placed directly on wounds and the leaf juice pro-
duces painkilling effects.
Noni Leaf Antibacterial Effects
Saludes JP et al. (2002). Phytother Res, 16, 683-685
Ethanol and hexane fractions from Morinda citrifolia leaf
showed antitubercular activity by killing 89% of the bac-
teria in vitro, comparable to 97% kill by the anti-TB drug
Rifampicin at the same concentration.
Noni Leaf Antioxidant Effects
West et al. (2009). International Journal of Food Science
and Technology, 44, 2142-2146.
The aqueous infusion prepared from noni leaves from Tahiti
exhibited greater radical scavenging (antioxidant) activity
than green tea infusion. Zin et al. (2006). Food Chem, 94,
169-178. Methanol fractions from defatted noni leaf juice
showed strong antioxidant activities comparable to that of
alpha-tocopherol
Shown in Product Identification Guide, page 319
Unicity International
THE MAKE LIFE BETTER COMPANY
1201 NORTH 800 EAST
OREM, UT 84097
Direct Inquiries to:
(801) 226-2600
www.unicity.net
science@unicity.net
Products of Unicity International are distributed through
independent distributors.
BIO-C™
[bı¯o¯ se¯]
DESCRIPTION
Bio-C™ is a vitamin C nutritional supplement.
Bio-C™ is a yellow, water-soluble, crystalline powder
pressed into a tablet. Each Bio-C™ tablet consists of a pro-
prietary blend of ascorbyl palmitate, calcium ascorbate, as-
corbic acid, magnesium ascorbate and 75 mg of citrus biofla-
vonoids. In addition to the active ingredients, each 800 mg
tablet contains dextrose, microcrystalline cellulose, silicon
dioxide, magnesium stearate, and stearic acid.
BENEFITS AND RESEARCH
Vitamin C (ascorbic acid) is a water-soluble vitamin that is
used in the body to form cartilage, collagen, muscles and
blood vessels. Vitamin C is a potent antioxidant that can
protect small molecules such as proteins, carbohydrates,
nucleic acids and lipids from damage caused by free radicals
that are generated through the course of normal metabo-
lism or through exposure to external toxins and pollutants
(e.g. ultraviolet radiation from the sun or smoking). Vitamin
C can also regenerate other antioxidants like vitamin E. Ad-
ditionally, vitamin C is required for the synthesis of carni-
tine, a molecule involved in the transport of fats across the
mitochondrial membrane, as well as the synthesis of norep-
inephrine, a neurotransmitter.*
USAGE
Take one tablet morning and night with a meal.
SAFETY AND WARNINGS
Bio-C™ is well tolerated. Some gastrointestinal discomfort
may be experienced as with any dietary supplement.
HOW SUPPLIED
Available in tablets.
REFERENCES
Carr, AC and Frei B. (1999), American Journal of Clinical
Nutrition 96: 1086-1107.
Jacob, RA and Sotoudeh G. (2002), Nutrition in Clinical
Care 5: 66-74.
Deruelle F, Baron B. (2008), Journal of Alternative and
Complementary Medicine 14:1291-1298.
Levine M, Rumsey SC, Daruwala R, Park JB, Wang Y.
(1999), The Journal of the American Medical Association
281: 1415-1423.
* THESE STATEMENTS HAVE NOT BEEN EVALUATED
BY THE FOOD AND DRUG ADMINISTRATION. THIS
PRODUCT IS NOT INTENDED TO DIAGNOSE, TREAT,
CURE, OR PREVENT ANY DISEASE.
BIOS LIFE® CARDIO
[bı¯-o¯s lı¯f kärd-e¯-o¯]
Advanced Fiber and Nutrient Drink
DESCRIPTION
Bios Life® Cardio is a fiber based, vitamin rich nutritional
supplement. Bios Life® Cardio contains a blend of soluble
and insoluble fibers, phytosterols, policosanol, an extract of
Chrysanthemum morifolium, vitamins, and minerals that
when combined with a healthy diet and exercise may lower
total serum cholesterol, lower triglyceride levels and reduce
the risk of heart disease.
Bios Life® Cardio is light orange in color. It is a hygroscopic
crystalline powder that is generally soluble in water. Each
serving of Bios Life® Cardio contains 3 g of fiber, 1 g of phy-
tosterols, 6 mg of policosanol, and 12.5 mg of an extract of
Chrysamthemum morifolium. In addition to these active in-
gredients, each serving of Bios Life® Cardio contains mal-
todextrin, citric acid, orange juice powder, sucralose and
orange flavor.
BENEFITS AND RESEARCH
It’s estimated that Americans consume 10-12 g of total fiber
per day, less than half the amount of the recommended daily
intake. Epidemiological and clinical studies have correlated
low daily fiber intake with higher incidences of hyperinsu-
linemia, hypercholesterolemia, and elevated risks of cardio-
vascular disease.
Bios Life® Cardio is a nutritional supplement designed to
increased daily fiber intake. Each serving of Bios Life®
Cardio contains three grams of dietary fiber. When taken
three times a day this achieves nearly half of the recom-
mended daily value of fiber. Fiber supplementation has
been shown to decrease preprandial and postprandial glu-
cose levels and lower LDL cholesterol and apolipoprotein B
levels.
In addition to fiber supplementation, Bios Life® Cardio con-
tains a patented blend of phytosterols, policosanol, Chry-
santhemum morifolium, vitamins and minerals. This blend
of ingredients optimizes cholesterol levels through a combi-
nation of four mechanisms. First, the soluble fiber matrix
prevents cholesterol reabsorption in the gastrointestinal
tract through bile-acid sequestration. Second, the phytoster-
ols reduce dietary absorption of cholesterol. Third, poli-
cosanol inhibits hepatic synthesis of cholesterol mediated
through HMG-CoA reductase. Fourth, Chrysanthemum
morifolium provides phytonutrients that enhance conver-
sion of cholesterol to 7-␣-hydryoxycholesterol. The four
mechanisms provide a synergistic approach to optimizing
cholesterol levels. Research has shown that this product
may serve as a first line treatment option for mild hyper-
cholesterolemia, as well as adjunct therapy for lipid lower-
ing pharmaceutical intervention.
SUGGESTED USAGE
Dissolve the contents of one packet or one scoop into 8 to
10 fl. oz. of liquid (water or juice) and stir vigorously. Drink
immediately. Use 15-20 minutes prior to meals up to three
times daily.
Complimentary CME for PDR-listed products at PDR.net BIOS LIFE CARDIO ● UNICITY/3551
Visit PDR.net to register for Product Safety Alerts and to download mobilePDRா - free to U.S. prescribers
SAFETY AND WARNINGS
Bios Life® Cardio is well tolerated. There may be mild gas-
trointestinal discomfort, such as increased flatulence or
loose stools, during the first month of initial use due to the
increased uptake of dietary fiber. This GI disturbance usu-
ally disappears within the first thirty days. If the GI dis-
comfort persists, reduce the number of servings of Bios
Life® Cardio. If the GI discomfort further persists, stop tak-
ing the product and consult your physician. Taking this
product without adequate liquid can result in complications.
If you are a diabetic, consult a physician for proper use of
this product, as the chromium may reduce the need for med-
ication.
HOW SUPPLIED
Bios Life® Cardio is packaged in single-serving foil packets
or in bulk canisters.
REFERENCES
Sprecher, DL and Pearce GL (2002), Metabolism 51:
1166–70.
Verdegem, PJE; Freed, S and Joffe D (2005), American Di-
abetes Assocation 65th Scientific Sessions, San Diego, CA.
Duenas, V; Duenas, J; Burke, E and Verdegem, PJE (2006),
7th International Conference on Arteriosclerosis, Thrombo-
sis, and Vascular Biology, American Heart Association,
Denver, CO.
Verdegem, PJE (2007), Current Topics in Nutraceutical
Research 5: 1-6
US Patent 6,933,291.
* THESE STATEMENTS HAVE NOT BEEN EVALUATED
BY THE FOOD AND DRUG ADMINISTRATION. THIS
PRODUCT IS NOT INTENDED TO DIAGNOSE, TREAT,
CURE, OR PREVENT ANY DISEASE.
Shown in Product Identification Guide, page 320
BIOS LIFE® SLIM™
[bı¯-o¯s lı¯f slim]
Advanced Fiber and Nutrient Drink
DESCRIPTION
Bios Life® Slim™ is a fiber-based, vitamin-rich nutritional
supplement. Bios Life® Slim™ contains a blend of soluble
and insoluble fibers, Unicity® 7ϫ technology, phytosterols,
policosanol, an extract of Chrysanthemum morifolium, vita-
mins, and minerals that when combined with a healthy diet
and exercise may lower total serum cholesterol, reduce the
risk of heart disease and help achieve and maintain a
healthy body weight.
Bios Life® Slim™ is light orange in color. It is a hygroscopic
crystalline powder that is generally soluble in water. Each
serving of Bios Life® Slim™ contains 4 g of fiber, 1 g of phy-
tosterols, 750 mg of Unicity 7ϫ, 6 mg of policosanol and
12.5 mg of an extract of Chrysanthemum morifolium. In ad-
dition to these active ingredients each serving of Bios Life®
Slim™ contains maltodextrin, citric acid, orange juice pow-
der, sucralose and orange flavor.
BENEFITS AND RESEARCH
It’s estimated that Americans consume 10-12 g of total fiber
per day, less than half the amount of the recommended daily
intake. Epidemiological and clinical studies have correlated
low daily fiber intake with higher incidences of obesity, hy-
perinsulinemia, hypercholesterolemia, and elevated risks of
cardiovascular disease.
Bios Life® Slim™ is a nutritional supplement designed to
increase fiber intake. Each serving of Bios Life® Slim™ con-
tains four grams of fiber. When taken three times a day this
achieves half of the recommended daily value of fiber. Fiber
supplementation has been shown to decrease preprandial
and postprandial glucose levels; lower LDL cholesterol and
apolipoprotein B levels; increase satiety and facilitate
weight loss.
In addition to fiber supplementation, Bios Life® Slim™ con-
tains a patented blend of phytosterols, policosanol, Chry-
santhemum morifolium, vitamins and minerals. Bios Life®
Slim™ facilitates weight loss through five distinct mecha-
nisms. First, the soluble fiber matrix promotes an increase
in satiety. Second, Bios Life® Slim™ improves cholesterol
levels. Reduction in LDL content removes a potent inhibitor
of lipolysis. Third, Bios Life® Slim™ improves blood glucose
levels. Maintaining appropriate serum glucose levels re-
duces hyperinsulinemia and promotes insulin sensitivity.
Reducing insulin levels permits fatty acid oxidation to oc-
cur. Fourth, Bios Life® Slim™ restores appropriate leptin
signaling. Lastly, Bios Life® Slim™, reduces triglyceride
levels allowing for leptin to cross the blood-brain barrier
and effect its mechanism of action. Research has shown that
this product may serve as a first line treatment option for
mild hypercholesterolemia, as well as adjunct therapy for
lipid lowering pharmaceutical intervention.
SUGGESTED USAGE
Dissolve the contents of one packet or one scoop into 8 to
10 fl. oz. of liquid (water or juice) and stir vigorously. Drink
immediately. Use 15-20 minutes before meals up to three
times daily.
SAFETY AND WARNINGS
Bios Life® Slim™ is well tolerated. There may be mild gas-
trointestinal discomfort, such as increased flatulence or
loose stools, during the first month of initial use due to the
increased uptake of dietary fiber. This GI disturbance usu-
ally disappears within the first thirty days. If the GI
discomfort persists, reduce the number of servings of Bios
Life® Slim™. If the GI discomfort further persists, stop tak-
ing the product and consult your physician. Taking this
product without adequate liquid can result in complications.
If you are a diabetic, consult a physician for proper use of
this product, as the chromium may reduce the need for med-
ication.
HOW SUPPLIED
Bios Life® Slim™ is packaged in single-serving foil packets
or in bulk canisters.
REFERENCES
Sprecher, DL and Pearce GL (2002), Metabolism 51:
1166-70.
Verdegem, PJE; Freed, S and Joffe D (2005), American Di-
abetes Assocation 65th Scientific Sessions, San Diego, CA.
Slavin, JL, (2005) Nutrition 21: 411-418.
Delzenne NM, Cani PD, (2005) Current Opinion Clincal
Nutrition & Metabolic Care 8: 636-640
Duenas, V; Duenas, J; Burke, E and Verdegem, PJE (2006),
7th International Conference on Arteriosclerosis, Thrombo-
sis, and Vascular Biology, American Heart Association,
Denver, CO.
Verdegem, PJE (2007), Current Topics in Nutraceutical
Research 5: 1-6
US Patent 6,933,291.
* THESE STATEMENTS HAVE NOT BEEN EVALUATED
BY THE FOOD AND DRUG ADMINISTRATION. THIS
PRODUCT IS NOT INTENDED TO DIAGNOSE, TREAT,
CURE, OR PREVENT ANY DISEASE.
Shown in Product Identification Guide, page 320
BONEMATE® PLUS
[bo¯n-ma¯t plu˘s]
Advanced Bone Health Formula
DESCRIPTION
BoneMate® Plus is specially formulated to help maintain
optimal bone health.* It contains three forms of calcium and
vitamin D to maximize absorption and aid in the support of
healthy bones, teeth, nerves, heart, and muscle tissue.
BoneMate® Plus is a light gray in color and is soluble in
water. Each serving of BoneMate® Plus contains the follow-
ing active ingredients 600mg of calcium, 300mg of magne-
sium, 30 mg of vitamin C, 2000 IU of vitamin D, 0.5mg of
boron, 5 mg of zinc, 1mg of manganese, 1mg of copper, and
20mg of vitamin K. In addition, it also contains the inactive
ingredients microcrystalline cellulose, croscarmellose so-
dium, and magnesium stearate.
BENEFITS AND RESEARCH
Calcium is the most common mineral in the body. Almost
99% of the calcium in our body is found in the bones and
teeth. Bone is a dynamic tissue that is constantly being re-
modeled throughout our lives. A chronically low calcium in-
take in growing individuals may prevent the attainment of
optimal peak bone mass. Once peak bone mass has been
achieved, inadequate calcium intake may contribute to ac-
celerated bone loss and eventually to osteoporosis.
Vitamin D, a secosteroid that is produced by the body upon
exposure to the sun, is required for optimal calcium absorp-
tion. To ensure that calcium absorption is not limited by
inadequate vitamin D levels, BoneMate® Plus contains
2000 IU of vitamin D per serving. In addition to facilitating
calcium absorption, Vitamin D has been shown to target
over 2000 different genes in the body. Vitamin D deficiency
has been associated with increased risks for heart disease,
stroke, diabetes, depression, osteoarthritis, chronic pain,
and osteoporosis.
USAGE
Take two tablets twice daily with a meal.
SAFETY AND WARNINGS
BoneMate® Plus is well tolerated. Some gastrointestinal
discomfort may be experienced as with any dietary supple-
ment. The Food and Nutrition Board of the Institute of
Medicine has set the tolerable upper level (UL) of intake for
calcium in adults at 2,500 milligrams (mg) of calcium/day.
HOW SUPPLIED
Available as tablets or as a powder.
REFERENCES
Weaver CM, Heaney RP. Calcium. In: Shils M, Olson JA,
Shike M, Ross AC, eds. Modern Nutrition in Health and
Disease. 9th ed. Baltimore: Williams & Wilkins; 1999:
141-155.
Heaney RP. Calcium, dairy products and osteoporosis. J Am
Coll Nutr. 2000;19(2 Suppl):83S-99S.
Food and Nutrition Board, Institute of Medicine. Calcium.
Dietary Reference Intakes: Calcium, Phosphorus,
Magnesium, Vitamin D, and Fluoride. Washington, D.C.:
National Academy Press; 1997:71-145.
Reid IR. Therapy of osteoporosis: calcium, vitamin D, and
exercise. Am J Med Sci 1996;312:278-86. Food and Nutri-
tion Board, Institute of Medicine. Calcium. Dietary Refer-
ence Intakes: Calcium, Phosphorus, Magnesium, Vitamin
D, and Fluoride. Washington, D.C.: National Academy
Press; 1997:71-145.
* THESE STATEMENTS HAVE NOT BEEN EVALUATED
BY THE FOOD AND DRUG ADMINISTRATION. THIS
PRODUCT IS NOT INTENDED TO DIAGNOSE, TREAT,
CURE, OR PREVENT ANY DISEASE.
CARDIO-BASICS™
Caring for your heart*
DESCRIPTION
Cardio-Basics™ is a nutritional supplement that combines
multivitamins, minerals and antioxidants to support the
cardiovascular system.
Cardio-Basics™ is a light orange, water-soluble powder
pressed into tablets. Each tablet of Cardio-Basics™ con-
tains the following vitamins, minerals, amino acids and an-
tioxidants: beta-carotene (vitamin A), thiamine (vitamin
B1), riboflavin (vitamin B2), niacin (vitamin B3), calcium
d-pantothenate (vitamin B5), pyridoxine hydrochloride (vi-
tamin B6), folate (vitamin B9), cyanocobalamin (vitamin
B12), ascorbic acid and ascorbyl palmitate (vitamin C), cho-
lecalciferol (vitamin D), d-alpha-tocopherol (vitamin E), bi-
otin, calcium, chromium, copper, magnesium, manganese,
molybdenum, phosphorus, potassium, selenium, sodium,
zinc, L-arginine, L-carnitine, L-cysteine, L-lysine, L-proline,
inositol, coenzyme Q10, and maritime pine extract. In addi-
tion to those active ingredients each tablet also contains mi-
crocrystalline cellulose, sucrose, fatty acid esters, silicon di-
oxide, magnesium stearate, and maltodextrin.
BENEFITS AND RESEARCH
According to the Center for Disease Control and Prevention,
one American will die every minute as a result of heart
disease. Narrowing of the arterial walls can lead to blocked
blood flow to the brain. A healthy lifestyle including being
physically active, not smoking, and making good food
choices can lead to a reduction of heart disease.
Cardio-Basics™ provides the vitamins, minerals and anti-
oxidants needed for a healthy heart. In clinical studies, par-
ticipants using Cardio-Basics™ and Bio-C™ saw a signifi-
cant reduction in arterial wall thickness, removal of
calcification deposits and a reduced risk for cardiovascular
disease when compared to the placebo group. Cardio-
Basics™ provides the body with the necessary vitamins and
minerals needed to support a healthy vascular system.*
SUGGESTED USE
Take two tablets daily with food.
SAFETY AND WARNINGS
Cardio-Basics™ is well tolerated. Some gastrointestinal
discomfort may be experienced as with any dietary supple-
ment.
HOW SUPPLIED
Available in tablets
REFERENCES
Niedzwiekcki, A, Rath, M. (1996) Journal of Applied Nutri-
tion, 48: 67-78.
Jeejeebhoy, F, Keith, M, Freeman, M, Barr, A, McCall, M,
Kurian, R, Mazer, D, Errett, L, (2002), American Heart
Journal 143: 1092-1100.
Verdgem, PJE, Lonky, S, Curley, S. (2005) 7th Conference
on Arteriosclerosis, Thrombosis and Vascular Biology.
Lloyd-Jones D, Adams R, Carnethon M, DeSimone G, Fer-
guson TB, Flegal K, Ford E, Furie K, Go A, Greenlund K,
Haase N, Hailpern S, Ho M, Howard V, Kissela B, Kittner S,
Lackland D, Lisabeth L, Marelli A, McDermott M, Meigs J,
Mozaffarian D, Nichol G, O’Donnell C, Roger V, Rosamond
W, Sacco R, Sorlie P, Stafford R, Steinberger J, Hong Y;
(2009) Circulation, 119: 480-486.
* THESE STATEMENTS HAVE NOT BEEN EVALUATED
BY THE FOOD AND DRUG ADMINISTRATION. THIS
PRODUCT IS NOT INTENDED TO DIAGNOSE, TREAT,
CURE, OR PREVENT ANY DISEASE.
CARDIO-ESSENTIALS
Caring for your heart*
DESCRIPTION
Cardio-Essentials is a nutritional supplement for the heart.
Cardio-Essentials contains Coenzyme Q-10, L-carnitine,
L-taurine and Hawthorn berry.
3552/UNICITY ● BIOS LIFE CARDIO For the latest PDR product information, visit PDR.net
IMPORTANT NOTICE: Updated drug information is sent bi-monthly via the PDRா Update Insert. For monthly email updates, register at PDR.net.
Cardio-Essentials is a light tan, water-soluble powder. Each
capsule of Cardio-Essentials contains 100 mg of Coenzyme
Q-10 and 3.5 g of a blend of L-carnitine, L-taurine, and
Hawthorn berry. In addition to those active ingredients,
each capsule also contains silicon dioxide, stearic acid and
calcium silicate.
BENEFITS AND RESEARCH
One of the leading causes of congestive heart failure (CHF),
left ventricular dysfunction, affects approximately 1.5% of
the population in the United States. CHF patients with left
ventricular dysfunction have reduced levels of Coenzyme
Q-10, L-carnitine and L-taurine and have an enlarged left
ventricle. In a clinical study, the combination of L-carnitine,
L-taurine, and Coenzyme Q10 was shown to benefit conges-
tive heart failure patients by reducing left ventricular size.
These ingredients are known to be important in providing
adequate energy for heart muscle. Cardio-Essentials pro-
vides adequate amounts of these ingredients, i.e. 100 mg of
CoQ10. Hawthorn extract is traditionally used in support-
ing the heart function.
SUGGESTED USE
Take three capsules twice a day with food.
SAFETY AND WARNINGS
Cardio-Essentials is well tolerated. Some gastrointestinal
discomfort may be experienced as with any dietary supple-
ment.
HOW SUPPLIED
Available in capsules
REFERENCES
Jeejeebhoy, F et al (2002), American Heart Journal 143
1092–1100.
* THESE STATEMENTS HAVE NOT BEEN EVALUATED
BY THE FOOD AND DRUG ADMINISTRATION. THIS
PRODUCT IS NOT INTENDED TO DIAGNOSE, TREAT,
CURE, OR PREVENT ANY DISEASE.
CM PLEX™ AND CM PLEX™ CREAM
[CM ple˘ks]
Proprietary fatty acid blend to help alleviate symptoms
of osteoarthritis*
DESCRIPTION
CM Plex and CM Plex Cream are a softgel and topical
cream, respectively, that contain a proprietary blend of cety-
lated fatty acids, soy and fish oil.
CM Plex is an opaque powder that is insoluble in water. One
softgel capsule of CM Plex contains 350 mg of cetylated
fatty acids, 160 mg of soy oil and 25 mg of salmon oil. In
addition to these active ingredients, each softgel capsule
contains glycerin and St. John’s Bread.
CM Plex Cream is an off-white powder that is insoluble in
water. One gram of CM Plex Cream contains 7.7 mg of cety-
lated fatty acids and olive oil. In addition to these active
ingredients CM Plex Cream also contains glyceryl stearate,
glycerin, lecithin, tocopheryl acetate, benzyl alcohol,
phenoxyethanol, carbomer, PEG-100 stearate, sodium hy-
droxide, methylparaben, propylparaben, butylparaben, eth-
ylparaben, isobutylparaben and citrus aurantium bergamia
(Bergamot) fruit oil.
BENEFITS AND RESEARCH
Cetyl myristoleate and related fatty acids have been proven
to improve joint health through their anti- inflammatory ef-
fects. A clinical study indicated that subjects exhibited im-
provements in knee flexion compared to placebo. A second
study indicated the cream is effective for improving knee
range of motion, ability to climb stairs, rise from a chair and
walk, balance, strength, and endurance.*
SUGGESTED USE
Softgels: Take one to two softgels three times daily with
meals.
Cream: Apply generously onto clean skin and gently mas-
sage until the cream disappears. Repeat 3 to 4 times daily
as necessary. For maximum results combine both products.
SAFETY AND WARNINGS
CM Plex Softgels and Cream are well tolerated. Some gas-
trointestinal discomfort may be experienced with CM Plex
Softgels as with any dietary supplement.
HOW SUPPLIED
CM Plex is available in soft gels and as a topical cream.
REFERENCES
Hesslink, R et al (2002), Journal of Rheumatology 29, 1708–
1712.
Kraemer, WJ et al (2004), Journal of Rheumatology 31,
767–774.
* THESE STATEMENTS HAVE NOT BEEN EVALUATED
BY THE FOOD AND DRUG ADMINISTRATION. THIS
PRODUCT IS NOT INTENDED TO DIAGNOSE, TREAT
CURE, OR PREVENT ANY DISEASE.
Shown in Product Identification Guide, page 321
IMMUNIZEN®
[ı˘m mo¯o¯ nı˘ ze˘n]
DESCRIPTION
Immunizen® is a nutritional supplement for boosting the
immune system.
Immunizen® is a modestly water soluble, white crystalline
powder. Immunizen® consists of a proprietary ingredient
blend of colostrum, arabinogalactan, 1,3, 1,6 yeast beta-
glucans and lactoferrin. In addition to the active ingredi-
ents, each 835 mg capsule of Immunizen® contains natural
gelatin, stearic acid and silicon dioxide.
BENEFITS AND RESEARCH
Immunizen® combines the positive immune modulating ef-
fects of colostrum, arabinogalactans, yeast beta-glucans and
lactoferrin to boost your body’s natural defenses to foreign
antigens. Colostrum is composed of immunoglobulins that
bolster the body’s immune system by providing immunity
against various pathogens.
Beta-glucans are generally derived from the cell walls of the
yeast species Saccharomyces cerevisiae. Beta-glucans are
potent immuno-modulating agents that prime both the in-
nate and adaptive immune systems.
USAGE
Take six capsules with water one to two hours before a meal
for 10 days as needed.
SAFETY AND WARNINGS
Immunizen® is well tolerated. Some gastrointestinal dis-
comfort may be experienced as with any dietary supple-
ment.
HOW SUPPLIED
Available in capsules.
REFERENCES
Lilius EM, Marnila P. (2001), Current Opinion in Infectious
Diseases 14:295-300.
Hammarström L, Weiner CK. (2008), Advances in Experi-
mental Medicine and Biology 606: 321-343.
Chan GC, Chan WK, Sze DM. (2009), The Journal of Hem-
atology and Oncology, 2: 25-
* THESE STATEMENTS HAVE NOT BEEN EVALUATED
BY THE FOOD AND DRUG ADMINISTRATION. THIS
PRODUCT IS NOT INTENDED TO DIAGNOSE, TREAT,
CURE, OR PREVENT ANY DISEASE.
OMEGALIFE-3™
[o¯me˘ga¯-lı¯f 3]
Omega-3 Fatty Acid Supplementation
DESCRIPTION
OmegaLife-3™ is a blend of omega-3 fatty acids designed to
help maintain healthy cardiovascular and cerebral function
as well as aiding in the prevention of age-related macular
degeneration.
OmegaLife-3™ is an amber-colored, semi-viscous, fat-
soluble liquid. Each serving of OmegaLife-3™ contains the
following active ingredients 800 mg eicosapentaenoic acid
(EPA), 400 mg docosahexaenoic acid (DHA), and vitamin E.
In addition, it also contains the inactive ingredients gelatin,
glycerin, purified water, and orange oil. OmegaLife-3™ has
been molecularly distilled to ensure exceptionally pure oil
and includes orange oil to prevent a fishy after taste.
BENEFITS AND RESEARCH
Clinical research suggests that fish oil can help support
proper brain and visual function. In 2002 the FDA approved
supplementation of DHA in infant formula. DHA is poten-
tially important in fetal and infant neural development, in
that DHA and arachidonic acid have been shown to be in-
corporated into brain and retinal cell membranes—particu-
larly during the third trimester and early infant life.
DHA is the predominant structural fatty acid in the central
nervous system and in the retina of the eyes.
EPA supports the synthesis of important compounds in the
body. EPA is the precursor of thromboxane and leukotriene,
compounds involved in supporting healthy circulation. They
also promote healthy blood vessels.*
Evidence is accumulating that increasing intakes of EPA
and DHA can decrease the risk of cardiovascular disease by
preventing arrhythmias, decreasing the risk of thrombosis,
decreasing triglyceride levels, slowing the growth of ather-
osclerotic plaque, and decreasing inflammation.*
The U.S. Food and Drug Administration (FDA) has stated
that, “Supportive but not conclusive research shows that
consumption of EPA and DHA omega-3 fatty acids may re-
duce the risk of coronary heart disease.”
USAGE
Take two softgels per day with a meal.
SAFETY AND WARNINGS
OmegaLife-3™ is well tolerated. Some gastrointestinal
discomfort may be experienced as with any dietary sup-
plement. Common side effects include a “fishy” taste upon
eructation.
HOW SUPPLIED
Available in softgels.
REFERENCES
Barter P, Ginsberg HN. Effectiveness of combined statin
plus omega-3 fatty acid therapy for mixed dyslipidemia. Am
J Cardiol. 2008 Oct 15:102(8):1040-5
Lee JH, Harris WS, et al. Omega-3 fatty acids for cardiopro-
tection. Mayo Clin Proc. 2008 Mar;83(3):324-32.
SanGiovanni JP, Chew EY, Sperduto RD, et al. The relation-
ship of dietary omega-3 long-chain polyunsaturated fatty
acid intake with incident age-related macular degeneration:
AREDS report no. 23. Arch Ophthalmol. 2008 Sep;126(9):
1274-9.
SanGiovanni JP, Parra-Cabrera S, Colditz GA, Berkey CS,
Dwyer JT. Meta-analysis of dietary essential fatty acids and
long-chain polyunsaturated fatty acids as they relate to vi-
sual resolution acuity in healthy preterm infants. Pediatrics
2000;105:1292-8.
Kris-Etherton PM, Harris WS, Appel LJ. Omega-3 fatty ac-
ids and cardiovascular disease: new recommendations from
the American Heart Association. Arterioscler Thromb Vasc
Biol. 2003;23(2):151-152.
* THESE STATEMENTS HAVE NOT BEEN EVALUATED
BY THE FOOD AND DRUG ADMINISTRATION. THIS
PRODUCT IS NOT INTENDED TO DIAGNOSE, TREAT,
CURE, OR PREVENT ANY DISEASE.
BIOS LIFE® VISION ESSENTIALS™
[bı¯-o¯s lı¯f vizh-uhn e¯-sen-shuhls]
Clinically proven to support healthy eyes and vision.*
DESCRIPTION
Bios Life® Vision Essentials™ is a nutritional supplement
for maintaining healthy eyes. Bios Life® Vision
Essentials™contains vitamin C, vitamin E, zinc, natural
beta carotene, lutein, zeaxanthin, and anthocyanidins from
wild bilberry, wild blueberry, strawberry, cranberry, elder-
berry and raspberries.
Bios Life® Vision Essentials™ is a purple crystalline pow-
der that is water soluble. In addition to the active ingredi-
ents vitamin C, vitamin E, zinc, natural beta carotene, lu-
tein, zeaxanthin, and anthocyanidins from wild bilberry,
wild blueberry, strawberry, cranberry, elderberry and rasp-
berries, each 425 mg capsule contains silicon dioxide, micro-
crystalline cellulose and is packaged in vegetarian capsules.
BENEFITS AND RESEARCH
Antioxidants from the carotenoid chemical family, such as
beta carotene, lutein and zeaxanthin, play an important
role in eye health. Clinical studies have demonstrated that
lutein and zeaxanthin are concentrated to the retina and
lens of the eye. Low concentrations of these compounds in
the retina are associated with age-related macular degener-
ation (AMD). Supplementation with high levels of lutein
can restore the lutein concentration in the retina. Further
supplementation of vitamins C and E and A (in the form of
beta-carotene) along with zinc, and copper delayed the onset
of AMD. Additional support for the eyes comes from a
proprietary berry blend included in Bios Life® Vision
Essentials™. This proprietary berry blend contains antho-
cyanidins, anti-oxidant compounds that support the vascu-
lature within the eye, reducing the risk for diabetic retino-
pathies.
USAGE
Take two capsules per day with a meal.
SAFETY AND WARNINGS
Bios Life® Vision Essentials™ is well tolerated. Some
gastrointestinal discomfort may be experienced as with any
dietary supplement.
HOW SUPPLIED
Available in vegetarian capsules.
REFERENCES
Krishnadev N, Meleth AD, Chew EY (2010) “Nutritional
supplements for age-related macular degeneration.” Cur-
rent Opinion in Opthamology 21:184-189.
Ma L, Lin XM, Zou ZY, Xu XR, Li Y, Xu R. (2009) “A 12-week
lutein supplementation improves visual function in Chinese
people with long-term computer display light exposure.”
British Journal of Nutrition 102: 186-190.
Yagi, A, Fujimoto, K, Michihiro, K, Goh, B, Tsi, D, Nagai, H,
(2009) “The effect of lutein supplementation on visual fa-
tigue: A psychophysiological analysis”. Applied Ergonomics
40:1047-1054.
Complimentary CME for PDR-listed products at PDR.net BIOS LIFE VISION ESSENTIALS ● UNICITY/3553
Visit PDR.net to register for Product Safety Alerts and to download mobilePDRா - free to U.S. prescribers
Age Related Eye Disease Study Group, (2001) “A random-
ized, placebo-controlled, clinical trial of high-dose supple-
mentation with vitamins C and E, beta carotene, and zinc
for age-related macular degeneration and vision loss:
AREDS report no. 8”. Archives of Ophthalmology. 10:
1417-36.
* THESE STATEMENTS HAVE NOT BEEN EVALUATED
BY THE FOOD AND DRUG ADMINISTRATION. THIS
PRODUCT IS NOT INTENDED TO DIAGNOSE, TREAT
CURE, OR PREVENT ANY DISEASE.
Upsher-Smith Laboratories, Inc.
6701 EVENSTAD DRIVE
MINNEAPOLIS, MN 55369
For Medical Information Contact:
Write: Medical Information Department
or call: (800) 654-2299
(during business hours-8:00 am to 5:00 pm CST)
SLO-NIACIN® TABLETS
[slow-nI-a-sin]
(polygel® controlled-release niacin)
Dietary Supplement
250 mg, 500 mg, 750 mg
DESCRIPTION
Slo-Niacin® Tablets are manufactured utilizing a unique,
patented polygel® controlled-release delivery system. This
exclusive technology assures the gradual and measured re-
lease of niacin (nicotinic acid) and is designed to reduce the
incidence of flushing and itching commonly associated with
niacin use. Slo-Niacin® Tablets are available in 250 mg,
500 mg, and 750 mg strengths.
SUGGESTED USE
Slo-Niacin® is a member of the vitamin B-complex group
(nicotinic acid, vitamin B3) and is suggested as a dietary
supplement. This product has the advantage of a slower re-
lease of niacin than conventional dosage forms. This may
permit its use by those who do not tolerate immediate-
release tablets.
DIRECTIONS
250 mg: Adults—one Slo-Niacin® Tablet morning or eve-
ning, or as directed by a physician.
500 mg: Adults—one Slo-Niacin® Tablet morning or eve-
ning, or as directed by a physician.
750 mg: Adults—one Slo-Niacin® Tablet morning or eve-
ning, or as directed by a physician.
Before using more than 500 mg daily, consult a physician.
Note: Slo-Niacin® Tablets may be broken on the score line,
but should not be crushed or chewed.
Store at controlled room temperature, 15-30° C (59-86° F).
INFO & TIPS ON FLUSHING
What is flushing?
Flushing is a common side effect of niacin therapy, including
Slo-Niacin®. Flushing is associated with temporary itching
and tingling, feelings of warmth and headache, particularly
when beginning or increasing the dose. These effects seldom
require discontinuation of niacin.
Tips to avoid flushing
• Talk to your healthcare professional about taking 1 aspi-
rin or ibuprofen 30 minutes before taking Slo-Niacin®
Tablets
• Take Slo-Niacin® Tablets with a low-fat snack and cold
water
• Take Slo-Niacin® Tablets before going to bed
• Do not take Slo-Niacin® Tablets with spicy foods, alcohol,
coffee, tea, or other hot drinks
CAUTION
Niacin may cause temporary flushing, itching and tingling,
feelings of warmth and headache, particularly when begin-
ning, increasing amount or changing brand of niacin. These
effects seldom require discontinuing niacin use. Skin rash,
upset stomach, and low blood pressure when standing are
less common symptoms; if they persist, contact a physician.
WARNINGS
Slo-Niacin® Tablets should not be used by persons with a
known sensitivity or allergy to niacin. Persons with heart
disease, particularly those who have recurrent chest pain
(angina) or who recently suffered a heart attack, should
take niacin only under the supervision of a physician. Per-
sons taking high blood pressure or cholesterol-lowering
drugs should contact a physician before taking niacin be-
cause of possible interactions. Case reports of myopathy
(unexplained muscle related complaints, including discom-
fort, weakness, or tenderness) have been documented with
the use of HMG-CoA Reductase Inhibitors in combination
with lipid-altering doses of niacin therapy (Ն1 gram of nia-
cin per day). Do not take niacin unless recommended by and
taken under the supervision of a physician if you have any
of the following conditions: gallbladder disease, gout, arte-
rial bleeding, glaucoma, diabetes, impaired liver function,
peptic ulcer, pregnancy or lactating women. Increased uric
acid and glucose levels and abnormal liver function tests
have been reported in persons taking daily doses of 500 mg
or more of niacin.
Discontinue use and consult a physician immediately if any
of the following symptoms occur: persistent flu-like symp-
toms (nausea, vomiting, a general “not well” feeling); loss of
appetite; a decrease in urine output associated with dark-
colored urine; muscle discomfort such as tender, swollen
muscles or muscle weakness; irregular heartbeat; or cloudy
or blurry vision.
Keep out of reach of children.
INGREDIENTS
250 mg niacin (nicotinic acid), supplying 1,250% of the
Daily Value (DV) for niacin.
500 mg niacin (nicotinic acid), supplying 2,500% of the
Daily Value (DV) for niacin.
750 mg niacin (nicotinic acid), supplying 3,750% of the
Daily Value (DV) for niacin.
Each tablet also contains: hypromellose, hydrogenated veg-
etable oil, silicon dioxide, magnesium stearate, glyceryl
behenate, Red 40.
UPSHER-SMITH LABORATORIES, INC.
6701 Evenstad Drive
Maple Grove, MN 55369
©2002 Upsher-Smith Laboratories, Inc.
All Rights Reserved.
US Patents 5,126,145 and 5,268,181.
www.slo-niacin.com
1-800-654-2299
100792-02
Revised 0810
USANA Health Sciences, Inc.
3838 WEST PARKWAY BOULEVARD
SALT LAKE CITY, UT 84120-6336
Direct Inquiries to:
Ph: (801) 954 7860
Fax: (801) 954 7658
ACTIVE CALCIUM™
COMPOSITION
Each Active Calcium contains the following minerals:
Vitamin D3 (as Cholecalciferol) 100 IU
Vitamin K (as Phylloquinone) 15 mcg
Calcium (as Calcium Citrate and Carbonate) 200 mg
Magnesium (as Magnesium Citrate,
Amino Acid Chelate and Oxide)
100 mg
Boron (as Boron Citrate) 0.33 mg
Silicon (as Silicon Amino Acid Complex) 2.25 mg
ADVANTAGES
Each tablet contains a balanced blend of calcium, magne-
sium, vitamin D, vitamin K, boron and silicon; six nutrients
required for bone development, bone remodeling and skele-
tal health. This non-prescription product meets USP guide-
lines for potency (as applicable), uniformity and disintegra-
tion, and is manufactured according to pharmaceutical
cGMP standards.
RECOMMENDED USE
Take 4 tablets by mouth daily, preferably with meals.
SUPPLIED
Capsule-shaped tablet, mottled greenish-white color, with
clear film coating, and with USANA imprint. In bottle of 112
tablets.
CHELATED MINERAL
[keyЈ-la¯-te˘d]
mineral
COMPOSITION
Each Chelated Mineral contains the following minerals:
Calcium (As Calcium Citrate and Carbonate) 67.5 mg
Iodine (As Potassium Iodide) 75 mcg
Magnesium (As Magnesium Citrate and Amino
Acid Chelate) 75 mg
Zinc (As zinc citrate) 5 mg
Selenium (As L-selenomethionine and Amino
Acid Complex) 50 mcg
Copper (As Copper Gluconate) 0.5 mg
Manganese (As Manganese Gluconate) 1.25 mg
Chromium (As Chromium Polynicotinate
and Picolinate**) 75 mcg
Molybdenum (As Molybdenum Citrate) 1.25 mcg
Boron (As boron citrate) 0.75 mg
Silicon (As Silicon Amino Acid Complex) 1 mg
Vanadium (As Vanadium Citrate) 10 mcg
Ultra trace Minerals 0.75 mg
**Licensed under U.S. Patent 4,315,927.
ADVANTAGES
Each tablet contains a complete and balanced blend of es-
sential minerals in bioavailable forms. The Chelated
Mineral is designed to be taken with USANA’s Mega Anti-
oxidant to provide a full complement of essential nutrients
required for health. This non-prescription product meets
USP guidelines for potency (as applicable), uniformity and
disintegration, and is manufactured according to pharma-
ceutical cGMP standards.
RECOMMENDED USE
Take two (2) tablets twice daily, preferably with food.
SUPPLIED
Oblong shaped tablets, off-white color, with clear film coat-
ing with USANA imprint. In bottle of 112 tablets
COQUINONE® 30
[co¯Ј-kwi-no¯n]
COMPOSITION
Each CoQuinone 30 capsule contains the following:
Coenzyme Q10 30 mg
Alpha Lipoic Acid 12.5 mg
ADVANTAGES
CoQuinone 30 contains a hydrosoluble form of Coenzyme
Q10 (CoQ10) that is 2.5 times more bioavailable than mate-
rial supplied in dry tablet/capsule formulas. The higher
blood levels of CoQ10 supplied enhance mitochondrial pro-
duction of ATP. CoQ10 is a rate-limiting factor in the elec-
tron transport chain involved in mitochondrial production of
ATP. It is also involved in neutralizing free radicals gener-
ated during ATP production. As such, CoQ10 helps the body
maintain healthy skeletal and cardiac muscle. Alpha lipoic
acid is included in the formula as a lipid-soluble antioxidant
to recycle CoQ10 from the prooxidant form to the antioxi-
dant form. This non-prescription product meets USP guide-
lines for potency (where applicable), uniformity and disinte-
gration, and is manufactured according to cGMP standards.
RECOMMENDED USE
Take 1 or 2 capsules by mouth daily.
SUPPLIED
Oval shaped, soft gelatin capsule, annatto-colored, opaque,
imprinted with USANA in white edible ink. Capsules con-
tain an orange colored liquid. In bottle of 56 soft-gel cap-
sules.
MEGA ANTIOXIDANT
[me˘-ga˘ aenti-o˘xЈ-si-de˘nt]
COMPOSITION
Each Mega Antioxidant contains the following vitamins and
Minerals:
Vitamin A (as beta carotene) 3,750 IU
Vitamin C (as Calcium, Potassium,
Magnesium, & Zinc Ascorbates)
325 mg
Vitamin D3 (as Cholecalciferol) 450 IU
Vitamin E (as D-alpha Tocopheryl
Succinate)
100 IU
Vitamin K (as Phylloquinone) 15 mcg
Thiamin (as Thiamine HCL) 6.75 mg
Riboflavin 6.75 mg
Niacin and Niacinamide 10 mg
Vitamin B6 (as Pyridoxine HCL) 8 mg
Folate (as Folic Acid) 250 mcg
Vitamin B12 (as Cyanocobalamin) 50 mcg
Biotin 75 mcg
Pantothenic Acid (as D-Calcium
Pantothenate)
22.5 mg
Olivol ® (Olive Extract) 7.5 mg
Mixed Natural Tocopherols (D-gamma,
D-delta, D-beta Tocopherol)
8.5 mg
3554/UNICITY ● BIOS LIFE VISION ESSENTIALS For the latest PDR product information, visit PDR.net
IMPORTANT NOTICE: Updated drug information is sent bi-monthly via the PDRா Update Insert. For monthly email updates, register at PDR.net.

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  • 1. Tahitian Noni® Original Bioactive Increases Antioxidant Status and Improves Endurance in Highly Trained Athletes. Palu et al. 2008. Journal of Medicinal Plant Research, 2 (7), 154-158. In a placebo-controlled clinical trial involving 40 highly trained athletes, Tahitian Noni® Original Bioactive (TNJ) was shown to increase endurance by 21%, while it increased antioxidant status of the blood by 25%. Tahitian Noni® Original Bioactive Health Effects on Cervical Spondylosis. Akinbo et al. (2006). Nigerian Journal of Health and Bio- medical Sciences, 5, 6-11. A one month clinical trial with 90 cervical spondylosis patients found that drinking 30 mL of Tahitian Noni® Original Bioactive (TNJ) per day improved range of move- ment and pain in addition to further increased benefits from a combination of TNJ and standard therapy. Tahitian Noni® Original Bioactive Does Not Contain Ath- letic Banned Substances. Palu et al. (2008). Journal of Medicinal Plants Research 2(7): 154-158. A pilot study with 6 people drinking Tahitian Noni® Original Bioactive revealed the absence of all performance- enhancing drugs and substances banned by the World Anti Doping Association. Tahitian Noni® Original Bioactive Has DNA Protection Ef- fects. Wang et al. (2007). AACR Annual Meeting April 14-18. Los Angeles, CA Drinking 1 or 4 ounces of Tahitian Noni® Original Bioactive (TNJ) was shown to reduced the amount of MDA caused DNA damage by 53% in a double-blind, placebo-controlled, one month clinical trial involving 203 current heavy smok- ers. Tahitian Noni® Original Bioactive has a positive effect on postmenopausal women. Langford et al. (2004). The Journal of Alternative and Com- plementary Medicine, 10, 737-742. A three month, placebo controlled, pilot study, with 8 post- menopausal women showed that drinking 4 ounces of Tahitian Noni® Original Bioactive improved mood, energy, attenuated hearing loss, and showed evidence of potential anti-osteoporosis effect. Tahitian Noni® Original Bioactive Is Safe for Human Con- sumption. The EFSA Journal 2006, 376: 1-12. The European Food Safety Authority reports, “it is unlikely that consumption of noni juice, at the observed levels of in- take, induces adverse human liver effects.” Tahitian Noni® Original Bioactive Not a Significant Source of Potassium. A case report stated that the potassium content of noni juice was 56.3 mEq/L, or 65 mg/ounce, and may be a “surrepti- tious” source of potassium for patients with renal disease. (Mueller et al. Am J. Kidney Dis. 2000 35: 330–2). Mueller (USA Today, March 28, 2000) clarified his research, stating he did not analyze TNJ (Tahitian Noni® Original Bioac- tive), but rather a different brand of noni juice and that the amount of potassium was only “as much as you’d get in 2 inches of banana.” Tahitian Noni® Original Bioactive Not a Significant Source of Potassium. West et al. (2006). International Journal of Food Sciences and Nutrition, 57(7/8), 556-558.. Potassium content of Tahitian Noni® Original Bioactive is 30-50 mg per 1 ounce serving. This is a minor source when compared with bananas, yogurt, and other significant di- etary sources of potassium. Tahitian Noni® Original Bioactive Does Not Contain Vitamin K. Palu ‘AK et al., Am J Hematol 2005 79: 79-82. Vitamin K has not been detected in Tahitian Noni® Original Bioactive and in noni fruits from Tahiti. *Source: USDA Nutrient Database for Standard Reference. Noni Fruits from Tahiti Contains Iridoids Deng et al. (2010). Phytochemical Analysis. DOI: 10.1002/ pca.1246 Chemical research has revealed that iridoids are the major bioactive phytochemicals in noni fruit from Tahiti. The pres- ence of iridoids and their wide range of biological activities explain the health benefits of Tahitian Noni® Original Bio- active. Shown in Product Identification Guide, page 319 TAHITIAN NONI® NONI LEAF SERUM DESCRIPTION In an exclusive process known only to Tahitian Noni Inter- national, we’ve extracted the juice of the long-treasured noni leaf and made it into a soothing balm. Especially for skin that’s been exposed to the elements, this serum will condition and revitalize irritated, wind-chaffed, or sun- burned skin with lasting relief. Ingredients: TAHITIAN NONI® Exclusive Noni Leaf For- mula [Purified Water, Morinda citrifolia (Noni) Leaf Juice, Morinda citrifolia (Noni) Leaf Extract, Vanilla tahitensis (Tahitian Vanilla) Fruit Extract], Pentylene Glycol, Propylene Glycol, SD Alcohol 40-B, PEG-400 Laurate and Laureth-4, Sodium Dehydroacetate, Disodium EDTA, Phenoxyethanol, Fragrance, Acrylates/C10-30 Alkyl Acry- late Crosspolymer, Potassium Hydroxide. Suggested Use: Smooth over irritated skin as needed. Storage: Keep tightly closed in a dry place; do not expose to excessive heat. HOW SUPPLIED 1, 3 and 6 packs of cream, 1 oz/30 ml Packaged for Tahitian Noni International, a subsidiary of Morinda, Inc. Provo, UT 84604. USA. REFERENCES Tahitian Noni® Leaf Extract Topical Usage Promotes Wound Healing. Palu et al, (2010). Phytotherapy Research. DOI: 10.1002/ ptr.3150. A noni leaf ethanolic extract demonstrated significant wound healing effects in the mouse cutaneous assay by dou- bling the wound closure rate with 5.4 CT50. Tahitian Noni® Leaf Extract Offers Skin Protection. West et al. (2009). Journal of Natural Medicines, 63 (3), 351- 354. A clinical trial involving 25 people showed that noni leaf ex- tracts protected the skin against ultraviolet (UV) induced redness and swelling by approximately 350%. Noni Leaf Extracts Taken Internally Promotes Wound Heal- ing. Nayak BS et al. (2007). eCAM, 1-6. The ethanolic extract from the noni leaf significantly en- hanced wound contraction, decreased epithilialization time, and increased hydorxyproline, suggesting that noni leaf ex- tract has wound healing properties. Noni Leaf Preparation Has Tonic and Antiseptic Effect. Mannetje L. Morinda citrifolia L. in: Plant-Resources of South-East Asia (Edit.: E. Westphal, P. and C. M. Jansen). Pudoc Wageningen 1989, p. 185-187. A noni leaf preparation is used as a tonic and antiseptic. Leaves are placed directly on wounds and the leaf juice pro- duces painkilling effects. Noni Leaf Antibacterial Effects Saludes JP et al. (2002). Phytother Res, 16, 683-685 Ethanol and hexane fractions from Morinda citrifolia leaf showed antitubercular activity by killing 89% of the bac- teria in vitro, comparable to 97% kill by the anti-TB drug Rifampicin at the same concentration. Noni Leaf Antioxidant Effects West et al. (2009). International Journal of Food Science and Technology, 44, 2142-2146. The aqueous infusion prepared from noni leaves from Tahiti exhibited greater radical scavenging (antioxidant) activity than green tea infusion. Zin et al. (2006). Food Chem, 94, 169-178. Methanol fractions from defatted noni leaf juice showed strong antioxidant activities comparable to that of alpha-tocopherol Shown in Product Identification Guide, page 319 Unicity International THE MAKE LIFE BETTER COMPANY 1201 NORTH 800 EAST OREM, UT 84097 Direct Inquiries to: (801) 226-2600 www.unicity.net science@unicity.net Products of Unicity International are distributed through independent distributors. BIO-C™ [bı¯o¯ se¯] DESCRIPTION Bio-C™ is a vitamin C nutritional supplement. Bio-C™ is a yellow, water-soluble, crystalline powder pressed into a tablet. Each Bio-C™ tablet consists of a pro- prietary blend of ascorbyl palmitate, calcium ascorbate, as- corbic acid, magnesium ascorbate and 75 mg of citrus biofla- vonoids. In addition to the active ingredients, each 800 mg tablet contains dextrose, microcrystalline cellulose, silicon dioxide, magnesium stearate, and stearic acid. BENEFITS AND RESEARCH Vitamin C (ascorbic acid) is a water-soluble vitamin that is used in the body to form cartilage, collagen, muscles and blood vessels. Vitamin C is a potent antioxidant that can protect small molecules such as proteins, carbohydrates, nucleic acids and lipids from damage caused by free radicals that are generated through the course of normal metabo- lism or through exposure to external toxins and pollutants (e.g. ultraviolet radiation from the sun or smoking). Vitamin C can also regenerate other antioxidants like vitamin E. Ad- ditionally, vitamin C is required for the synthesis of carni- tine, a molecule involved in the transport of fats across the mitochondrial membrane, as well as the synthesis of norep- inephrine, a neurotransmitter.* USAGE Take one tablet morning and night with a meal. SAFETY AND WARNINGS Bio-C™ is well tolerated. Some gastrointestinal discomfort may be experienced as with any dietary supplement. HOW SUPPLIED Available in tablets. REFERENCES Carr, AC and Frei B. (1999), American Journal of Clinical Nutrition 96: 1086-1107. Jacob, RA and Sotoudeh G. (2002), Nutrition in Clinical Care 5: 66-74. Deruelle F, Baron B. (2008), Journal of Alternative and Complementary Medicine 14:1291-1298. Levine M, Rumsey SC, Daruwala R, Park JB, Wang Y. (1999), The Journal of the American Medical Association 281: 1415-1423. * THESE STATEMENTS HAVE NOT BEEN EVALUATED BY THE FOOD AND DRUG ADMINISTRATION. THIS PRODUCT IS NOT INTENDED TO DIAGNOSE, TREAT, CURE, OR PREVENT ANY DISEASE. BIOS LIFE® CARDIO [bı¯-o¯s lı¯f kärd-e¯-o¯] Advanced Fiber and Nutrient Drink DESCRIPTION Bios Life® Cardio is a fiber based, vitamin rich nutritional supplement. Bios Life® Cardio contains a blend of soluble and insoluble fibers, phytosterols, policosanol, an extract of Chrysanthemum morifolium, vitamins, and minerals that when combined with a healthy diet and exercise may lower total serum cholesterol, lower triglyceride levels and reduce the risk of heart disease. Bios Life® Cardio is light orange in color. It is a hygroscopic crystalline powder that is generally soluble in water. Each serving of Bios Life® Cardio contains 3 g of fiber, 1 g of phy- tosterols, 6 mg of policosanol, and 12.5 mg of an extract of Chrysamthemum morifolium. In addition to these active in- gredients, each serving of Bios Life® Cardio contains mal- todextrin, citric acid, orange juice powder, sucralose and orange flavor. BENEFITS AND RESEARCH It’s estimated that Americans consume 10-12 g of total fiber per day, less than half the amount of the recommended daily intake. Epidemiological and clinical studies have correlated low daily fiber intake with higher incidences of hyperinsu- linemia, hypercholesterolemia, and elevated risks of cardio- vascular disease. Bios Life® Cardio is a nutritional supplement designed to increased daily fiber intake. Each serving of Bios Life® Cardio contains three grams of dietary fiber. When taken three times a day this achieves nearly half of the recom- mended daily value of fiber. Fiber supplementation has been shown to decrease preprandial and postprandial glu- cose levels and lower LDL cholesterol and apolipoprotein B levels. In addition to fiber supplementation, Bios Life® Cardio con- tains a patented blend of phytosterols, policosanol, Chry- santhemum morifolium, vitamins and minerals. This blend of ingredients optimizes cholesterol levels through a combi- nation of four mechanisms. First, the soluble fiber matrix prevents cholesterol reabsorption in the gastrointestinal tract through bile-acid sequestration. Second, the phytoster- ols reduce dietary absorption of cholesterol. Third, poli- cosanol inhibits hepatic synthesis of cholesterol mediated through HMG-CoA reductase. Fourth, Chrysanthemum morifolium provides phytonutrients that enhance conver- sion of cholesterol to 7-␣-hydryoxycholesterol. The four mechanisms provide a synergistic approach to optimizing cholesterol levels. Research has shown that this product may serve as a first line treatment option for mild hyper- cholesterolemia, as well as adjunct therapy for lipid lower- ing pharmaceutical intervention. SUGGESTED USAGE Dissolve the contents of one packet or one scoop into 8 to 10 fl. oz. of liquid (water or juice) and stir vigorously. Drink immediately. Use 15-20 minutes prior to meals up to three times daily. Complimentary CME for PDR-listed products at PDR.net BIOS LIFE CARDIO ● UNICITY/3551 Visit PDR.net to register for Product Safety Alerts and to download mobilePDRா - free to U.S. prescribers
  • 2. SAFETY AND WARNINGS Bios Life® Cardio is well tolerated. There may be mild gas- trointestinal discomfort, such as increased flatulence or loose stools, during the first month of initial use due to the increased uptake of dietary fiber. This GI disturbance usu- ally disappears within the first thirty days. If the GI dis- comfort persists, reduce the number of servings of Bios Life® Cardio. If the GI discomfort further persists, stop tak- ing the product and consult your physician. Taking this product without adequate liquid can result in complications. If you are a diabetic, consult a physician for proper use of this product, as the chromium may reduce the need for med- ication. HOW SUPPLIED Bios Life® Cardio is packaged in single-serving foil packets or in bulk canisters. REFERENCES Sprecher, DL and Pearce GL (2002), Metabolism 51: 1166–70. Verdegem, PJE; Freed, S and Joffe D (2005), American Di- abetes Assocation 65th Scientific Sessions, San Diego, CA. Duenas, V; Duenas, J; Burke, E and Verdegem, PJE (2006), 7th International Conference on Arteriosclerosis, Thrombo- sis, and Vascular Biology, American Heart Association, Denver, CO. Verdegem, PJE (2007), Current Topics in Nutraceutical Research 5: 1-6 US Patent 6,933,291. * THESE STATEMENTS HAVE NOT BEEN EVALUATED BY THE FOOD AND DRUG ADMINISTRATION. THIS PRODUCT IS NOT INTENDED TO DIAGNOSE, TREAT, CURE, OR PREVENT ANY DISEASE. Shown in Product Identification Guide, page 320 BIOS LIFE® SLIM™ [bı¯-o¯s lı¯f slim] Advanced Fiber and Nutrient Drink DESCRIPTION Bios Life® Slim™ is a fiber-based, vitamin-rich nutritional supplement. Bios Life® Slim™ contains a blend of soluble and insoluble fibers, Unicity® 7ϫ technology, phytosterols, policosanol, an extract of Chrysanthemum morifolium, vita- mins, and minerals that when combined with a healthy diet and exercise may lower total serum cholesterol, reduce the risk of heart disease and help achieve and maintain a healthy body weight. Bios Life® Slim™ is light orange in color. It is a hygroscopic crystalline powder that is generally soluble in water. Each serving of Bios Life® Slim™ contains 4 g of fiber, 1 g of phy- tosterols, 750 mg of Unicity 7ϫ, 6 mg of policosanol and 12.5 mg of an extract of Chrysanthemum morifolium. In ad- dition to these active ingredients each serving of Bios Life® Slim™ contains maltodextrin, citric acid, orange juice pow- der, sucralose and orange flavor. BENEFITS AND RESEARCH It’s estimated that Americans consume 10-12 g of total fiber per day, less than half the amount of the recommended daily intake. Epidemiological and clinical studies have correlated low daily fiber intake with higher incidences of obesity, hy- perinsulinemia, hypercholesterolemia, and elevated risks of cardiovascular disease. Bios Life® Slim™ is a nutritional supplement designed to increase fiber intake. Each serving of Bios Life® Slim™ con- tains four grams of fiber. When taken three times a day this achieves half of the recommended daily value of fiber. Fiber supplementation has been shown to decrease preprandial and postprandial glucose levels; lower LDL cholesterol and apolipoprotein B levels; increase satiety and facilitate weight loss. In addition to fiber supplementation, Bios Life® Slim™ con- tains a patented blend of phytosterols, policosanol, Chry- santhemum morifolium, vitamins and minerals. Bios Life® Slim™ facilitates weight loss through five distinct mecha- nisms. First, the soluble fiber matrix promotes an increase in satiety. Second, Bios Life® Slim™ improves cholesterol levels. Reduction in LDL content removes a potent inhibitor of lipolysis. Third, Bios Life® Slim™ improves blood glucose levels. Maintaining appropriate serum glucose levels re- duces hyperinsulinemia and promotes insulin sensitivity. Reducing insulin levels permits fatty acid oxidation to oc- cur. Fourth, Bios Life® Slim™ restores appropriate leptin signaling. Lastly, Bios Life® Slim™, reduces triglyceride levels allowing for leptin to cross the blood-brain barrier and effect its mechanism of action. Research has shown that this product may serve as a first line treatment option for mild hypercholesterolemia, as well as adjunct therapy for lipid lowering pharmaceutical intervention. SUGGESTED USAGE Dissolve the contents of one packet or one scoop into 8 to 10 fl. oz. of liquid (water or juice) and stir vigorously. Drink immediately. Use 15-20 minutes before meals up to three times daily. SAFETY AND WARNINGS Bios Life® Slim™ is well tolerated. There may be mild gas- trointestinal discomfort, such as increased flatulence or loose stools, during the first month of initial use due to the increased uptake of dietary fiber. This GI disturbance usu- ally disappears within the first thirty days. If the GI discomfort persists, reduce the number of servings of Bios Life® Slim™. If the GI discomfort further persists, stop tak- ing the product and consult your physician. Taking this product without adequate liquid can result in complications. If you are a diabetic, consult a physician for proper use of this product, as the chromium may reduce the need for med- ication. HOW SUPPLIED Bios Life® Slim™ is packaged in single-serving foil packets or in bulk canisters. REFERENCES Sprecher, DL and Pearce GL (2002), Metabolism 51: 1166-70. Verdegem, PJE; Freed, S and Joffe D (2005), American Di- abetes Assocation 65th Scientific Sessions, San Diego, CA. Slavin, JL, (2005) Nutrition 21: 411-418. Delzenne NM, Cani PD, (2005) Current Opinion Clincal Nutrition & Metabolic Care 8: 636-640 Duenas, V; Duenas, J; Burke, E and Verdegem, PJE (2006), 7th International Conference on Arteriosclerosis, Thrombo- sis, and Vascular Biology, American Heart Association, Denver, CO. Verdegem, PJE (2007), Current Topics in Nutraceutical Research 5: 1-6 US Patent 6,933,291. * THESE STATEMENTS HAVE NOT BEEN EVALUATED BY THE FOOD AND DRUG ADMINISTRATION. THIS PRODUCT IS NOT INTENDED TO DIAGNOSE, TREAT, CURE, OR PREVENT ANY DISEASE. Shown in Product Identification Guide, page 320 BONEMATE® PLUS [bo¯n-ma¯t plu˘s] Advanced Bone Health Formula DESCRIPTION BoneMate® Plus is specially formulated to help maintain optimal bone health.* It contains three forms of calcium and vitamin D to maximize absorption and aid in the support of healthy bones, teeth, nerves, heart, and muscle tissue. BoneMate® Plus is a light gray in color and is soluble in water. Each serving of BoneMate® Plus contains the follow- ing active ingredients 600mg of calcium, 300mg of magne- sium, 30 mg of vitamin C, 2000 IU of vitamin D, 0.5mg of boron, 5 mg of zinc, 1mg of manganese, 1mg of copper, and 20mg of vitamin K. In addition, it also contains the inactive ingredients microcrystalline cellulose, croscarmellose so- dium, and magnesium stearate. BENEFITS AND RESEARCH Calcium is the most common mineral in the body. Almost 99% of the calcium in our body is found in the bones and teeth. Bone is a dynamic tissue that is constantly being re- modeled throughout our lives. A chronically low calcium in- take in growing individuals may prevent the attainment of optimal peak bone mass. Once peak bone mass has been achieved, inadequate calcium intake may contribute to ac- celerated bone loss and eventually to osteoporosis. Vitamin D, a secosteroid that is produced by the body upon exposure to the sun, is required for optimal calcium absorp- tion. To ensure that calcium absorption is not limited by inadequate vitamin D levels, BoneMate® Plus contains 2000 IU of vitamin D per serving. In addition to facilitating calcium absorption, Vitamin D has been shown to target over 2000 different genes in the body. Vitamin D deficiency has been associated with increased risks for heart disease, stroke, diabetes, depression, osteoarthritis, chronic pain, and osteoporosis. USAGE Take two tablets twice daily with a meal. SAFETY AND WARNINGS BoneMate® Plus is well tolerated. Some gastrointestinal discomfort may be experienced as with any dietary supple- ment. The Food and Nutrition Board of the Institute of Medicine has set the tolerable upper level (UL) of intake for calcium in adults at 2,500 milligrams (mg) of calcium/day. HOW SUPPLIED Available as tablets or as a powder. REFERENCES Weaver CM, Heaney RP. Calcium. In: Shils M, Olson JA, Shike M, Ross AC, eds. Modern Nutrition in Health and Disease. 9th ed. Baltimore: Williams & Wilkins; 1999: 141-155. Heaney RP. Calcium, dairy products and osteoporosis. J Am Coll Nutr. 2000;19(2 Suppl):83S-99S. Food and Nutrition Board, Institute of Medicine. Calcium. Dietary Reference Intakes: Calcium, Phosphorus, Magnesium, Vitamin D, and Fluoride. Washington, D.C.: National Academy Press; 1997:71-145. Reid IR. Therapy of osteoporosis: calcium, vitamin D, and exercise. Am J Med Sci 1996;312:278-86. Food and Nutri- tion Board, Institute of Medicine. Calcium. Dietary Refer- ence Intakes: Calcium, Phosphorus, Magnesium, Vitamin D, and Fluoride. Washington, D.C.: National Academy Press; 1997:71-145. * THESE STATEMENTS HAVE NOT BEEN EVALUATED BY THE FOOD AND DRUG ADMINISTRATION. THIS PRODUCT IS NOT INTENDED TO DIAGNOSE, TREAT, CURE, OR PREVENT ANY DISEASE. CARDIO-BASICS™ Caring for your heart* DESCRIPTION Cardio-Basics™ is a nutritional supplement that combines multivitamins, minerals and antioxidants to support the cardiovascular system. Cardio-Basics™ is a light orange, water-soluble powder pressed into tablets. Each tablet of Cardio-Basics™ con- tains the following vitamins, minerals, amino acids and an- tioxidants: beta-carotene (vitamin A), thiamine (vitamin B1), riboflavin (vitamin B2), niacin (vitamin B3), calcium d-pantothenate (vitamin B5), pyridoxine hydrochloride (vi- tamin B6), folate (vitamin B9), cyanocobalamin (vitamin B12), ascorbic acid and ascorbyl palmitate (vitamin C), cho- lecalciferol (vitamin D), d-alpha-tocopherol (vitamin E), bi- otin, calcium, chromium, copper, magnesium, manganese, molybdenum, phosphorus, potassium, selenium, sodium, zinc, L-arginine, L-carnitine, L-cysteine, L-lysine, L-proline, inositol, coenzyme Q10, and maritime pine extract. In addi- tion to those active ingredients each tablet also contains mi- crocrystalline cellulose, sucrose, fatty acid esters, silicon di- oxide, magnesium stearate, and maltodextrin. BENEFITS AND RESEARCH According to the Center for Disease Control and Prevention, one American will die every minute as a result of heart disease. Narrowing of the arterial walls can lead to blocked blood flow to the brain. A healthy lifestyle including being physically active, not smoking, and making good food choices can lead to a reduction of heart disease. Cardio-Basics™ provides the vitamins, minerals and anti- oxidants needed for a healthy heart. In clinical studies, par- ticipants using Cardio-Basics™ and Bio-C™ saw a signifi- cant reduction in arterial wall thickness, removal of calcification deposits and a reduced risk for cardiovascular disease when compared to the placebo group. Cardio- Basics™ provides the body with the necessary vitamins and minerals needed to support a healthy vascular system.* SUGGESTED USE Take two tablets daily with food. SAFETY AND WARNINGS Cardio-Basics™ is well tolerated. Some gastrointestinal discomfort may be experienced as with any dietary supple- ment. HOW SUPPLIED Available in tablets REFERENCES Niedzwiekcki, A, Rath, M. (1996) Journal of Applied Nutri- tion, 48: 67-78. Jeejeebhoy, F, Keith, M, Freeman, M, Barr, A, McCall, M, Kurian, R, Mazer, D, Errett, L, (2002), American Heart Journal 143: 1092-1100. Verdgem, PJE, Lonky, S, Curley, S. (2005) 7th Conference on Arteriosclerosis, Thrombosis and Vascular Biology. Lloyd-Jones D, Adams R, Carnethon M, DeSimone G, Fer- guson TB, Flegal K, Ford E, Furie K, Go A, Greenlund K, Haase N, Hailpern S, Ho M, Howard V, Kissela B, Kittner S, Lackland D, Lisabeth L, Marelli A, McDermott M, Meigs J, Mozaffarian D, Nichol G, O’Donnell C, Roger V, Rosamond W, Sacco R, Sorlie P, Stafford R, Steinberger J, Hong Y; (2009) Circulation, 119: 480-486. * THESE STATEMENTS HAVE NOT BEEN EVALUATED BY THE FOOD AND DRUG ADMINISTRATION. THIS PRODUCT IS NOT INTENDED TO DIAGNOSE, TREAT, CURE, OR PREVENT ANY DISEASE. CARDIO-ESSENTIALS Caring for your heart* DESCRIPTION Cardio-Essentials is a nutritional supplement for the heart. Cardio-Essentials contains Coenzyme Q-10, L-carnitine, L-taurine and Hawthorn berry. 3552/UNICITY ● BIOS LIFE CARDIO For the latest PDR product information, visit PDR.net IMPORTANT NOTICE: Updated drug information is sent bi-monthly via the PDRா Update Insert. For monthly email updates, register at PDR.net.
  • 3. Cardio-Essentials is a light tan, water-soluble powder. Each capsule of Cardio-Essentials contains 100 mg of Coenzyme Q-10 and 3.5 g of a blend of L-carnitine, L-taurine, and Hawthorn berry. In addition to those active ingredients, each capsule also contains silicon dioxide, stearic acid and calcium silicate. BENEFITS AND RESEARCH One of the leading causes of congestive heart failure (CHF), left ventricular dysfunction, affects approximately 1.5% of the population in the United States. CHF patients with left ventricular dysfunction have reduced levels of Coenzyme Q-10, L-carnitine and L-taurine and have an enlarged left ventricle. In a clinical study, the combination of L-carnitine, L-taurine, and Coenzyme Q10 was shown to benefit conges- tive heart failure patients by reducing left ventricular size. These ingredients are known to be important in providing adequate energy for heart muscle. Cardio-Essentials pro- vides adequate amounts of these ingredients, i.e. 100 mg of CoQ10. Hawthorn extract is traditionally used in support- ing the heart function. SUGGESTED USE Take three capsules twice a day with food. SAFETY AND WARNINGS Cardio-Essentials is well tolerated. Some gastrointestinal discomfort may be experienced as with any dietary supple- ment. HOW SUPPLIED Available in capsules REFERENCES Jeejeebhoy, F et al (2002), American Heart Journal 143 1092–1100. * THESE STATEMENTS HAVE NOT BEEN EVALUATED BY THE FOOD AND DRUG ADMINISTRATION. THIS PRODUCT IS NOT INTENDED TO DIAGNOSE, TREAT, CURE, OR PREVENT ANY DISEASE. CM PLEX™ AND CM PLEX™ CREAM [CM ple˘ks] Proprietary fatty acid blend to help alleviate symptoms of osteoarthritis* DESCRIPTION CM Plex and CM Plex Cream are a softgel and topical cream, respectively, that contain a proprietary blend of cety- lated fatty acids, soy and fish oil. CM Plex is an opaque powder that is insoluble in water. One softgel capsule of CM Plex contains 350 mg of cetylated fatty acids, 160 mg of soy oil and 25 mg of salmon oil. In addition to these active ingredients, each softgel capsule contains glycerin and St. John’s Bread. CM Plex Cream is an off-white powder that is insoluble in water. One gram of CM Plex Cream contains 7.7 mg of cety- lated fatty acids and olive oil. In addition to these active ingredients CM Plex Cream also contains glyceryl stearate, glycerin, lecithin, tocopheryl acetate, benzyl alcohol, phenoxyethanol, carbomer, PEG-100 stearate, sodium hy- droxide, methylparaben, propylparaben, butylparaben, eth- ylparaben, isobutylparaben and citrus aurantium bergamia (Bergamot) fruit oil. BENEFITS AND RESEARCH Cetyl myristoleate and related fatty acids have been proven to improve joint health through their anti- inflammatory ef- fects. A clinical study indicated that subjects exhibited im- provements in knee flexion compared to placebo. A second study indicated the cream is effective for improving knee range of motion, ability to climb stairs, rise from a chair and walk, balance, strength, and endurance.* SUGGESTED USE Softgels: Take one to two softgels three times daily with meals. Cream: Apply generously onto clean skin and gently mas- sage until the cream disappears. Repeat 3 to 4 times daily as necessary. For maximum results combine both products. SAFETY AND WARNINGS CM Plex Softgels and Cream are well tolerated. Some gas- trointestinal discomfort may be experienced with CM Plex Softgels as with any dietary supplement. HOW SUPPLIED CM Plex is available in soft gels and as a topical cream. REFERENCES Hesslink, R et al (2002), Journal of Rheumatology 29, 1708– 1712. Kraemer, WJ et al (2004), Journal of Rheumatology 31, 767–774. * THESE STATEMENTS HAVE NOT BEEN EVALUATED BY THE FOOD AND DRUG ADMINISTRATION. THIS PRODUCT IS NOT INTENDED TO DIAGNOSE, TREAT CURE, OR PREVENT ANY DISEASE. Shown in Product Identification Guide, page 321 IMMUNIZEN® [ı˘m mo¯o¯ nı˘ ze˘n] DESCRIPTION Immunizen® is a nutritional supplement for boosting the immune system. Immunizen® is a modestly water soluble, white crystalline powder. Immunizen® consists of a proprietary ingredient blend of colostrum, arabinogalactan, 1,3, 1,6 yeast beta- glucans and lactoferrin. In addition to the active ingredi- ents, each 835 mg capsule of Immunizen® contains natural gelatin, stearic acid and silicon dioxide. BENEFITS AND RESEARCH Immunizen® combines the positive immune modulating ef- fects of colostrum, arabinogalactans, yeast beta-glucans and lactoferrin to boost your body’s natural defenses to foreign antigens. Colostrum is composed of immunoglobulins that bolster the body’s immune system by providing immunity against various pathogens. Beta-glucans are generally derived from the cell walls of the yeast species Saccharomyces cerevisiae. Beta-glucans are potent immuno-modulating agents that prime both the in- nate and adaptive immune systems. USAGE Take six capsules with water one to two hours before a meal for 10 days as needed. SAFETY AND WARNINGS Immunizen® is well tolerated. Some gastrointestinal dis- comfort may be experienced as with any dietary supple- ment. HOW SUPPLIED Available in capsules. REFERENCES Lilius EM, Marnila P. (2001), Current Opinion in Infectious Diseases 14:295-300. Hammarström L, Weiner CK. (2008), Advances in Experi- mental Medicine and Biology 606: 321-343. Chan GC, Chan WK, Sze DM. (2009), The Journal of Hem- atology and Oncology, 2: 25- * THESE STATEMENTS HAVE NOT BEEN EVALUATED BY THE FOOD AND DRUG ADMINISTRATION. THIS PRODUCT IS NOT INTENDED TO DIAGNOSE, TREAT, CURE, OR PREVENT ANY DISEASE. OMEGALIFE-3™ [o¯me˘ga¯-lı¯f 3] Omega-3 Fatty Acid Supplementation DESCRIPTION OmegaLife-3™ is a blend of omega-3 fatty acids designed to help maintain healthy cardiovascular and cerebral function as well as aiding in the prevention of age-related macular degeneration. OmegaLife-3™ is an amber-colored, semi-viscous, fat- soluble liquid. Each serving of OmegaLife-3™ contains the following active ingredients 800 mg eicosapentaenoic acid (EPA), 400 mg docosahexaenoic acid (DHA), and vitamin E. In addition, it also contains the inactive ingredients gelatin, glycerin, purified water, and orange oil. OmegaLife-3™ has been molecularly distilled to ensure exceptionally pure oil and includes orange oil to prevent a fishy after taste. BENEFITS AND RESEARCH Clinical research suggests that fish oil can help support proper brain and visual function. In 2002 the FDA approved supplementation of DHA in infant formula. DHA is poten- tially important in fetal and infant neural development, in that DHA and arachidonic acid have been shown to be in- corporated into brain and retinal cell membranes—particu- larly during the third trimester and early infant life. DHA is the predominant structural fatty acid in the central nervous system and in the retina of the eyes. EPA supports the synthesis of important compounds in the body. EPA is the precursor of thromboxane and leukotriene, compounds involved in supporting healthy circulation. They also promote healthy blood vessels.* Evidence is accumulating that increasing intakes of EPA and DHA can decrease the risk of cardiovascular disease by preventing arrhythmias, decreasing the risk of thrombosis, decreasing triglyceride levels, slowing the growth of ather- osclerotic plaque, and decreasing inflammation.* The U.S. Food and Drug Administration (FDA) has stated that, “Supportive but not conclusive research shows that consumption of EPA and DHA omega-3 fatty acids may re- duce the risk of coronary heart disease.” USAGE Take two softgels per day with a meal. SAFETY AND WARNINGS OmegaLife-3™ is well tolerated. Some gastrointestinal discomfort may be experienced as with any dietary sup- plement. Common side effects include a “fishy” taste upon eructation. HOW SUPPLIED Available in softgels. REFERENCES Barter P, Ginsberg HN. Effectiveness of combined statin plus omega-3 fatty acid therapy for mixed dyslipidemia. Am J Cardiol. 2008 Oct 15:102(8):1040-5 Lee JH, Harris WS, et al. Omega-3 fatty acids for cardiopro- tection. Mayo Clin Proc. 2008 Mar;83(3):324-32. SanGiovanni JP, Chew EY, Sperduto RD, et al. The relation- ship of dietary omega-3 long-chain polyunsaturated fatty acid intake with incident age-related macular degeneration: AREDS report no. 23. Arch Ophthalmol. 2008 Sep;126(9): 1274-9. SanGiovanni JP, Parra-Cabrera S, Colditz GA, Berkey CS, Dwyer JT. Meta-analysis of dietary essential fatty acids and long-chain polyunsaturated fatty acids as they relate to vi- sual resolution acuity in healthy preterm infants. Pediatrics 2000;105:1292-8. Kris-Etherton PM, Harris WS, Appel LJ. Omega-3 fatty ac- ids and cardiovascular disease: new recommendations from the American Heart Association. Arterioscler Thromb Vasc Biol. 2003;23(2):151-152. * THESE STATEMENTS HAVE NOT BEEN EVALUATED BY THE FOOD AND DRUG ADMINISTRATION. THIS PRODUCT IS NOT INTENDED TO DIAGNOSE, TREAT, CURE, OR PREVENT ANY DISEASE. BIOS LIFE® VISION ESSENTIALS™ [bı¯-o¯s lı¯f vizh-uhn e¯-sen-shuhls] Clinically proven to support healthy eyes and vision.* DESCRIPTION Bios Life® Vision Essentials™ is a nutritional supplement for maintaining healthy eyes. Bios Life® Vision Essentials™contains vitamin C, vitamin E, zinc, natural beta carotene, lutein, zeaxanthin, and anthocyanidins from wild bilberry, wild blueberry, strawberry, cranberry, elder- berry and raspberries. Bios Life® Vision Essentials™ is a purple crystalline pow- der that is water soluble. In addition to the active ingredi- ents vitamin C, vitamin E, zinc, natural beta carotene, lu- tein, zeaxanthin, and anthocyanidins from wild bilberry, wild blueberry, strawberry, cranberry, elderberry and rasp- berries, each 425 mg capsule contains silicon dioxide, micro- crystalline cellulose and is packaged in vegetarian capsules. BENEFITS AND RESEARCH Antioxidants from the carotenoid chemical family, such as beta carotene, lutein and zeaxanthin, play an important role in eye health. Clinical studies have demonstrated that lutein and zeaxanthin are concentrated to the retina and lens of the eye. Low concentrations of these compounds in the retina are associated with age-related macular degener- ation (AMD). Supplementation with high levels of lutein can restore the lutein concentration in the retina. Further supplementation of vitamins C and E and A (in the form of beta-carotene) along with zinc, and copper delayed the onset of AMD. Additional support for the eyes comes from a proprietary berry blend included in Bios Life® Vision Essentials™. This proprietary berry blend contains antho- cyanidins, anti-oxidant compounds that support the vascu- lature within the eye, reducing the risk for diabetic retino- pathies. USAGE Take two capsules per day with a meal. SAFETY AND WARNINGS Bios Life® Vision Essentials™ is well tolerated. Some gastrointestinal discomfort may be experienced as with any dietary supplement. HOW SUPPLIED Available in vegetarian capsules. REFERENCES Krishnadev N, Meleth AD, Chew EY (2010) “Nutritional supplements for age-related macular degeneration.” Cur- rent Opinion in Opthamology 21:184-189. Ma L, Lin XM, Zou ZY, Xu XR, Li Y, Xu R. (2009) “A 12-week lutein supplementation improves visual function in Chinese people with long-term computer display light exposure.” British Journal of Nutrition 102: 186-190. Yagi, A, Fujimoto, K, Michihiro, K, Goh, B, Tsi, D, Nagai, H, (2009) “The effect of lutein supplementation on visual fa- tigue: A psychophysiological analysis”. Applied Ergonomics 40:1047-1054. Complimentary CME for PDR-listed products at PDR.net BIOS LIFE VISION ESSENTIALS ● UNICITY/3553 Visit PDR.net to register for Product Safety Alerts and to download mobilePDRா - free to U.S. prescribers
  • 4. Age Related Eye Disease Study Group, (2001) “A random- ized, placebo-controlled, clinical trial of high-dose supple- mentation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8”. Archives of Ophthalmology. 10: 1417-36. * THESE STATEMENTS HAVE NOT BEEN EVALUATED BY THE FOOD AND DRUG ADMINISTRATION. THIS PRODUCT IS NOT INTENDED TO DIAGNOSE, TREAT CURE, OR PREVENT ANY DISEASE. Upsher-Smith Laboratories, Inc. 6701 EVENSTAD DRIVE MINNEAPOLIS, MN 55369 For Medical Information Contact: Write: Medical Information Department or call: (800) 654-2299 (during business hours-8:00 am to 5:00 pm CST) SLO-NIACIN® TABLETS [slow-nI-a-sin] (polygel® controlled-release niacin) Dietary Supplement 250 mg, 500 mg, 750 mg DESCRIPTION Slo-Niacin® Tablets are manufactured utilizing a unique, patented polygel® controlled-release delivery system. This exclusive technology assures the gradual and measured re- lease of niacin (nicotinic acid) and is designed to reduce the incidence of flushing and itching commonly associated with niacin use. Slo-Niacin® Tablets are available in 250 mg, 500 mg, and 750 mg strengths. SUGGESTED USE Slo-Niacin® is a member of the vitamin B-complex group (nicotinic acid, vitamin B3) and is suggested as a dietary supplement. This product has the advantage of a slower re- lease of niacin than conventional dosage forms. This may permit its use by those who do not tolerate immediate- release tablets. DIRECTIONS 250 mg: Adults—one Slo-Niacin® Tablet morning or eve- ning, or as directed by a physician. 500 mg: Adults—one Slo-Niacin® Tablet morning or eve- ning, or as directed by a physician. 750 mg: Adults—one Slo-Niacin® Tablet morning or eve- ning, or as directed by a physician. Before using more than 500 mg daily, consult a physician. Note: Slo-Niacin® Tablets may be broken on the score line, but should not be crushed or chewed. Store at controlled room temperature, 15-30° C (59-86° F). INFO & TIPS ON FLUSHING What is flushing? Flushing is a common side effect of niacin therapy, including Slo-Niacin®. Flushing is associated with temporary itching and tingling, feelings of warmth and headache, particularly when beginning or increasing the dose. These effects seldom require discontinuation of niacin. Tips to avoid flushing • Talk to your healthcare professional about taking 1 aspi- rin or ibuprofen 30 minutes before taking Slo-Niacin® Tablets • Take Slo-Niacin® Tablets with a low-fat snack and cold water • Take Slo-Niacin® Tablets before going to bed • Do not take Slo-Niacin® Tablets with spicy foods, alcohol, coffee, tea, or other hot drinks CAUTION Niacin may cause temporary flushing, itching and tingling, feelings of warmth and headache, particularly when begin- ning, increasing amount or changing brand of niacin. These effects seldom require discontinuing niacin use. Skin rash, upset stomach, and low blood pressure when standing are less common symptoms; if they persist, contact a physician. WARNINGS Slo-Niacin® Tablets should not be used by persons with a known sensitivity or allergy to niacin. Persons with heart disease, particularly those who have recurrent chest pain (angina) or who recently suffered a heart attack, should take niacin only under the supervision of a physician. Per- sons taking high blood pressure or cholesterol-lowering drugs should contact a physician before taking niacin be- cause of possible interactions. Case reports of myopathy (unexplained muscle related complaints, including discom- fort, weakness, or tenderness) have been documented with the use of HMG-CoA Reductase Inhibitors in combination with lipid-altering doses of niacin therapy (Ն1 gram of nia- cin per day). Do not take niacin unless recommended by and taken under the supervision of a physician if you have any of the following conditions: gallbladder disease, gout, arte- rial bleeding, glaucoma, diabetes, impaired liver function, peptic ulcer, pregnancy or lactating women. Increased uric acid and glucose levels and abnormal liver function tests have been reported in persons taking daily doses of 500 mg or more of niacin. Discontinue use and consult a physician immediately if any of the following symptoms occur: persistent flu-like symp- toms (nausea, vomiting, a general “not well” feeling); loss of appetite; a decrease in urine output associated with dark- colored urine; muscle discomfort such as tender, swollen muscles or muscle weakness; irregular heartbeat; or cloudy or blurry vision. Keep out of reach of children. INGREDIENTS 250 mg niacin (nicotinic acid), supplying 1,250% of the Daily Value (DV) for niacin. 500 mg niacin (nicotinic acid), supplying 2,500% of the Daily Value (DV) for niacin. 750 mg niacin (nicotinic acid), supplying 3,750% of the Daily Value (DV) for niacin. Each tablet also contains: hypromellose, hydrogenated veg- etable oil, silicon dioxide, magnesium stearate, glyceryl behenate, Red 40. UPSHER-SMITH LABORATORIES, INC. 6701 Evenstad Drive Maple Grove, MN 55369 ©2002 Upsher-Smith Laboratories, Inc. All Rights Reserved. US Patents 5,126,145 and 5,268,181. www.slo-niacin.com 1-800-654-2299 100792-02 Revised 0810 USANA Health Sciences, Inc. 3838 WEST PARKWAY BOULEVARD SALT LAKE CITY, UT 84120-6336 Direct Inquiries to: Ph: (801) 954 7860 Fax: (801) 954 7658 ACTIVE CALCIUM™ COMPOSITION Each Active Calcium contains the following minerals: Vitamin D3 (as Cholecalciferol) 100 IU Vitamin K (as Phylloquinone) 15 mcg Calcium (as Calcium Citrate and Carbonate) 200 mg Magnesium (as Magnesium Citrate, Amino Acid Chelate and Oxide) 100 mg Boron (as Boron Citrate) 0.33 mg Silicon (as Silicon Amino Acid Complex) 2.25 mg ADVANTAGES Each tablet contains a balanced blend of calcium, magne- sium, vitamin D, vitamin K, boron and silicon; six nutrients required for bone development, bone remodeling and skele- tal health. This non-prescription product meets USP guide- lines for potency (as applicable), uniformity and disintegra- tion, and is manufactured according to pharmaceutical cGMP standards. RECOMMENDED USE Take 4 tablets by mouth daily, preferably with meals. SUPPLIED Capsule-shaped tablet, mottled greenish-white color, with clear film coating, and with USANA imprint. In bottle of 112 tablets. CHELATED MINERAL [keyЈ-la¯-te˘d] mineral COMPOSITION Each Chelated Mineral contains the following minerals: Calcium (As Calcium Citrate and Carbonate) 67.5 mg Iodine (As Potassium Iodide) 75 mcg Magnesium (As Magnesium Citrate and Amino Acid Chelate) 75 mg Zinc (As zinc citrate) 5 mg Selenium (As L-selenomethionine and Amino Acid Complex) 50 mcg Copper (As Copper Gluconate) 0.5 mg Manganese (As Manganese Gluconate) 1.25 mg Chromium (As Chromium Polynicotinate and Picolinate**) 75 mcg Molybdenum (As Molybdenum Citrate) 1.25 mcg Boron (As boron citrate) 0.75 mg Silicon (As Silicon Amino Acid Complex) 1 mg Vanadium (As Vanadium Citrate) 10 mcg Ultra trace Minerals 0.75 mg **Licensed under U.S. Patent 4,315,927. ADVANTAGES Each tablet contains a complete and balanced blend of es- sential minerals in bioavailable forms. The Chelated Mineral is designed to be taken with USANA’s Mega Anti- oxidant to provide a full complement of essential nutrients required for health. This non-prescription product meets USP guidelines for potency (as applicable), uniformity and disintegration, and is manufactured according to pharma- ceutical cGMP standards. RECOMMENDED USE Take two (2) tablets twice daily, preferably with food. SUPPLIED Oblong shaped tablets, off-white color, with clear film coat- ing with USANA imprint. In bottle of 112 tablets COQUINONE® 30 [co¯Ј-kwi-no¯n] COMPOSITION Each CoQuinone 30 capsule contains the following: Coenzyme Q10 30 mg Alpha Lipoic Acid 12.5 mg ADVANTAGES CoQuinone 30 contains a hydrosoluble form of Coenzyme Q10 (CoQ10) that is 2.5 times more bioavailable than mate- rial supplied in dry tablet/capsule formulas. The higher blood levels of CoQ10 supplied enhance mitochondrial pro- duction of ATP. CoQ10 is a rate-limiting factor in the elec- tron transport chain involved in mitochondrial production of ATP. It is also involved in neutralizing free radicals gener- ated during ATP production. As such, CoQ10 helps the body maintain healthy skeletal and cardiac muscle. Alpha lipoic acid is included in the formula as a lipid-soluble antioxidant to recycle CoQ10 from the prooxidant form to the antioxi- dant form. This non-prescription product meets USP guide- lines for potency (where applicable), uniformity and disinte- gration, and is manufactured according to cGMP standards. RECOMMENDED USE Take 1 or 2 capsules by mouth daily. SUPPLIED Oval shaped, soft gelatin capsule, annatto-colored, opaque, imprinted with USANA in white edible ink. Capsules con- tain an orange colored liquid. In bottle of 56 soft-gel cap- sules. MEGA ANTIOXIDANT [me˘-ga˘ aenti-o˘xЈ-si-de˘nt] COMPOSITION Each Mega Antioxidant contains the following vitamins and Minerals: Vitamin A (as beta carotene) 3,750 IU Vitamin C (as Calcium, Potassium, Magnesium, & Zinc Ascorbates) 325 mg Vitamin D3 (as Cholecalciferol) 450 IU Vitamin E (as D-alpha Tocopheryl Succinate) 100 IU Vitamin K (as Phylloquinone) 15 mcg Thiamin (as Thiamine HCL) 6.75 mg Riboflavin 6.75 mg Niacin and Niacinamide 10 mg Vitamin B6 (as Pyridoxine HCL) 8 mg Folate (as Folic Acid) 250 mcg Vitamin B12 (as Cyanocobalamin) 50 mcg Biotin 75 mcg Pantothenic Acid (as D-Calcium Pantothenate) 22.5 mg Olivol ® (Olive Extract) 7.5 mg Mixed Natural Tocopherols (D-gamma, D-delta, D-beta Tocopherol) 8.5 mg 3554/UNICITY ● BIOS LIFE VISION ESSENTIALS For the latest PDR product information, visit PDR.net IMPORTANT NOTICE: Updated drug information is sent bi-monthly via the PDRா Update Insert. For monthly email updates, register at PDR.net.