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Biological Macroolecules
Chapter 3
Chapter 4
“Life is just a kind of chemistry,
of sufficient complexity
to permit reproduction and evolution.”


                                Cosmos:
                                A Personal
                                Voyage
Polymers
a substance that has
a molecular structure
consisting chiefly or entirely of
a large number of similar units
bonded together

                                    New
                                    Oxford
                                    American
                                    Dictionary
Biological Polymers
Proteins
Nucleic Acids
Carbohydrates
Lipids
Dehydration Synthesis
Hydrolysis
Proteins
Amino Acids
Figure 4-3 Essential Cell Biology (© Garland Science 2010)
(b) Transport proteins: Red blood cells contain the
  (a) Enzymes: Globular proteins called enzymes          protein hemoglobin, which transports oxygen and
  play a key role in many chemical reactions.            carbon dioxide in the body.




                                         (d) Structural proteins: Keratin forms hair, nails,
    (c) Structural proteins: Collagen    feathers, and components of horns.
    Is present in bones, tendons, and
    cartilage.



(e) Defensive proteins: White
                                                                                                               (f) Contractile proteins: Proteins
blood cells destroy cells without
                                                                                                               called act in and myosin are
the proper identity proteins and
                                                                                                               present in muscles.
make antibody proteins that
attack invaders.
Table 4-1 Essential Cell Biology (© Garland Science 2010)
Form-Function
Relationship
Protein
Structure
and Folding
Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display.




                                                                                                        Primary
                                                                                                        structure
                                                                                                                    Amino acids

                                                                                                H

                                                                                            N
Secondary                                                                                           C

structure                                                                                       C
                                                        N                   C       N
                                                                    C
                                                                                            O
                                                C
                                                                H O
                                                    C                                       H
                                                            N           C
                                                                                C       N
                                                   O

                                                                                O               C
                                                    H                       H
                                                                                        C
                                                    N               C       N
                                                            C
                                               C                                            O
                                                                    O
                                                                H
                                                C                                       H
             β-pleated sheet                                N       C
                                                                                C
                                                O                                       N

                                                                                O
                                                                                                C
                                                        α-helix                         C

                                                                                        O




            Tertiary
            structure




                                                   Quaternary
                                                   structure
Hierarchical
Organization
Denaturation
On Food and Cooking
Harold McGee
Nucleic
Acids
Nucleotides
Page 57




          Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display.




                          P
                                                                           P
Figure 4.12
Base Pairing
Page68_01
Carbohydrates
Monosaccharides
Glucose

Galactose

Fructose
Disaccharides
Maltose

Sucrose

Lactose
Polysaccharides
energy storage
in plants


Starch
      {  amylose


         amylopectin
energy storage
in animals


Glycogen
structure
for plants


Cellulose
structure
in animals


Chitin
Lipids
Hydrophobic substances
can be dissolved in lipids.
Fatty Acids
Saturated
Unsaturated
Glycerol
Glycerol
Triacylglyceride




Fat Molecule
Long-Term
Energy Storage
Phospholipids
Calories per gram

Carbohydrate        4
Protein             4
Fat                 9
On Food and Cooking
Harold McGee

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Biological macromolecules