CD is an autoimmune disease where ingesting gluten damages finger-like projections (villi) in the small intestine, preventing nutrient absorption. It affects people genetically susceptible and is diagnosed through blood tests detecting antibodies and intestinal biopsies. Managing CD requires a strict lifelong gluten-free diet to avoid symptoms like diarrhea, weight loss, and malnutrition. While there is no cure, following the diet can control the disease.

2. Introduction
What is CD
cause
s

3. CD is inherited. It’s etiology is
unknown. Its brought on by ingesting
foods containing gluten,
a protein found in wheat, barley and
rye. Symptoms vary from person to
person and its estimated that 2 to 3
million people in the U.S. alone are
unaware that they may have this
disease and 80% go undiagnosed.
CD affects all ages from the very
young to the elderly, genetic
susceptible individuals. In the small
intestines there are finger like
projections call Villi; these villi have
like a wave motion; moving the food
bulk back and forth. During this
process important nutrients and
vitamins are extracted to be utilized
by the body. This is the process of a
healthy intestine.

4. Gluten affects the Villi by
destroying or eroding these finger
like projection, until there is little
to nothing left. In mild cases you
may have patches, in severe cases
you have nothing the villi are
completely destroyed leaving a
smooth surface which can not
.
function. Below is a picture of a
normal and CD intestine

5. You will feel sick after ingesting
food containing gluten, and once
you stop the pain and symptoms go
away. There is a large spectrum of
Gastrointestinal tract symptom; as
Follows:
• Chronic diarrhea:
• Distended belly:
• Cramping and pain:
• Weight loss:
• Loss of appetite or a voracious appetite:
• Vomiting:
• Stool may be bulky, pale or foul:

6. New born aren’t born with CD, but one
parent has it then precaution have to be
taken with the infant. Breast milk will
give the new born antibodies and
immunities that the is needed. There are
test that will be given to the infant, but at
age 2 and above they will be tested with
the adults’ test (IgA TTG) every 2yrs.
Blood Test:
IgA –Tissue transglutaminase
antibody or for short IgA TTG A
tissue transglutaminase IgA and/or IgG
test is used as part of an evaluation for
certain autoimmune conditions, in
celiac disease.
The body produces two types of
antibodies that attack tTG:

7. immunoglobulin A (IgA) and
immunoglobulin G (IgG)in Celiac
measuring the IgA form of tTG antibody
in the blood is more useful in detecting
celiac disease because it's made in the
small intestine, where gluten causes
inflammation and irritation in sensitive
people.
Levels of the IgG form of tTG
antibody, on the other hand, are less
specific to celiac disease, but may still be
useful in diagnosing the condition in
people who are unable to make normal
amounts of IgA antibodies. So if this test
is positive of abnormal IgA the next test
to pre-formed is a small Intestinal
Mucosal Biopsy.

8. Mucosal Biopsy is a simple procedure and
can be completed within the hour.
A topical anesthetic is given to the back of
the throat. A small capsule and tube are
introduced and the patient is asked to
swallow.
The capsule contains a small camera with a
cutting edge. Once the capsule reaches its
destination a small sample of intestine
tissue is obtained. This tissue is then
checked under a microscope, for tissue
damage. If this test is positive then the next
step is diet changes.
This is where the patient will have to work
closely with the nutritionist and doctor to
help get better control of the celiac disease.

9. People with CD need to stay totally away
from Gluten and Gluten by-products, as
well as all over the counter medications
that use/or contain gluten. Sticking to
this special diet can leave you with a low
intake of Iron; Folic Acid; B-vitamin and
fiber. Beans is a good source of
replenishing these nutrients and
vitamins. But remember to eat in
moderation due to the gastrointestinal
discomfort, which
Can mimic symptoms of CD. Also it’s
recommended that you take calcium,
Vitamin-D and a multivitamin.
There is no cure for Celiac, but with
proper diet and vitamins it can be
Controlled.

10. Can be fatal if not detected and treated. In
time the damaged Villi can be repaired.
But as soon as you introduce gluten to
your body the problem will return.
Some people will have symptoms and
mistaken it for being an allergy. You need
to be aware of what gluten protein
products to stay away from.
• Wheat-scientific name:
Gliadins and Glutenins
• Rye-scientific name:
Secalins
• Barley-Scientific name:
Hordeins

11. There are books and agencies that
strictly deal with CD, make you
research the material, there's inform-
ation out there that is not giving you the
whole view of the disease. So when in
doubt ask you doctor and or
nutritionist. There’s a long list of foods
and by-products which may contain
gluten, one important factor is
breads, and bread by-products. There
are groups for discussion.
National support groups
Celiac Disease Foundation (CDF)
Raising our Celiac Kids (R.O.C.K.)
Celiac Sprue Association