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COSMETICS & 
HEALTH FOOD 
IS 
BILLION US DOLLAR 
INDUSTRY!!
Uttwiler Spätlauber-an Apple with an 
Excellent Storage Ability 
• Storage ability of apples was 
an important factor to 
guarantee fresh fruits over 
winter in the 18th century 
• Modern apple cultivars are 
selected for a sweet flavour 
and therefore the Uttwiler 
Spätlauber disappeared 
• Today the Uttwiler Spätlauber 
apple is an endangered apple 
variety with only a few trees 
left in the world
The Secret of Storage Ability 
• Longevityof cells 
• High acidand tannin 
concentrations 
• Undiscovered 
metabolites? 
Can we use this 
apple for skin 
care?
Plant Cell Culture Technology (PCT) 
• PCT makes it possible to 
cultivate cells of endangered 
and rare species 
• The technology is based on 
dedifferentiated plant cells 
• These cells are plant 
stemcells and can be 
cultivated in liquid systems
What are Stem Cells? 
• Stemcells have two 
properties: 
– Self-renewal – the ability to go 
through numerous cycles of 
cell division in an 
undifferentiated state 
– Differentiation – the capacity 
to differentiate into other cell 
types 
– Toti-, pluri-, multi-, unipotent 
stem cells
Plant StemCells Formation of CallusTissue 
• If a plant is wounded, a callus 
tissue is formed (wound 
healing tissue) 
• In the callus tissue the 
normal differentiated cells go 
back into a dedifferentiated 
form and become stem cells 
(not possible in humans) 
• Mechanism is controlled by 
different plant hormones 
(auxins)
PhytoCellTecTM by Mibelle Biochemistry
From Callus to Plants
PhytoCellTecTM
Advantages of PhytoCellTecTM 
• Preservation of endangered 
plants 
• Use of rare plants for cosmetic 
applications 
• Growth of plant cells in-vitro 
• Controllable and reproducible 
production of metabolites 
• No limitation of plant sources 
due to seasonal restrictions
PhytoCellTecTM Malus Domestica
Stem Cells in Skin
Epithelial Stem Cells
Hair Bulge Stem Cells
Study Result
Umbilical Cord derived MSC
Protect Against UV (Umbilical Cord Stem Cells)
Growth of Hair Follicle
Length of Hair Follicle
PhytoCellTecTM Malus Domestica 
Effecton Gene Expression in Senescent 
DermalFibroblasts
PhytoCellTecTM Malus Domestica 
Gene Profile (Microarray)
In-VivoStudy: 
Anti-WrinkleEffectof PhytoCellTecTM Malus 
Domestica
In-VivoStudy: 
Anti-WrinkleEffectof PhytoCellTecTM Malus 
Domestica
Properties of PhytoCellTecTM 
• PhytoCellTecTMis a preparation of plant stem 
cells 
• PhytoCellTecTMis produced in Switzerland by a 
novel plant cell culture technology 
• PhytoCellTecTMcontains plant stem cells to 
protect and maintain skin stem cells 
• The protection of skin stem cells is a 
breakthrough approach in anti-aging cosmetics 
• Studies showed that PhytoCellTecTMprotects 
human stem cells and rejuvenates them 
• PhytoCellTecTMdelays chronological aging
Claims 
• Delays senescence of essential 
cells 
• Protects longevity of skin stem 
cells 
• Protectionof skinstemcells 
• Rejuvenationof skin 
• Maintainsthepowerof 
regeneration 
• Decreasein wrinkles 
• Combatschronologicalaging
Application of PhytoCellTecTM 
• Face care of mature skin to 
rejuvenate the basal layer and extend 
the life span of basalv keratinocytes 
• Face care of all age to protect the 
most important cells in the skin 
which are the stem cells 
• Eye serum to improve firmness and 
rejuvenate the extracellularmatrix 
• Pure PhytoCellTecTMproduct can be 
used as a fresh cell extract to 
rejuvenate the skin extensively
Marketing Story for Costumers 
• PhytoCellTecTMplant stem cells are a 
breakthrough in anti-aging therapy 
• Skin stem cell treatment is a 
revolutionary new approach in cosmetics 
• Plant stem cells are extremely efficient 
but also safe to use 
• PhytoCellTecTMis based on real plant 
stem cells to trigger the rejuvenation of 
the skin 
• PhytoCellTecTMdelays the natural aging 
process by maintaining the activity of 
skin stem cells
Billi Lim is the Author of No.1 
International Best Selling Book 
"Dare To Fail" Series & The World #1 
Billi Lim 
(chairman)
Billi Lim, the author of the No.1 best – seller “Dare To Fail” 
Was born into a large family of 14. His days as a teenager, student and later in 
business have been checkered with lots 
of failures. He failed to get into the local university in his first attempt. 
He would have been rejected again in his second attempt had he not held a state 
bursary. 
He has failed a few times in his love life and has gone through an emotional ‘hell’.
artikel tentang penggunaan 
Stem Cell 
pernyataan dari 
Dr. Mantra Nandini, drg., SpBM(K)., 
MARS & Artikel yang diambil dari 
OKEHEALTH
Fungsi Utama dari Sel Induk 
Apel Kolagen adalah sebagai 
berikut : 
1. Memperbaiki sel yang rusak 
2. Mengangtifkan sel yang tidur 
3. Meregenerasi sel 
INFORMASI NILAI GIZI / NUTRITION FACTS : 
per serving 5g per serving 150g 
Energi 37.3kcal 1119kcal 
Lemak Total 0.04g 1.2g 
Karbohidrat Total 8.28g 248.4g 
Protein 0.95g 28.5g 
Kalsium 0 mg 0 mg
APPLE STEAM CELL with COLLAGEN dikembangkan 
dari bahan bahan alami yang berkualitas serta aman. 
bahan tambahan seperti telir salmon, ekstrak kolagen 
dari salmon, dan ekstrak sari sarang burung walet, 
membuat produk ini sangat efektif dalam membuat 
anda awet muda dan meningkatkan kesehatan.
THE END 
THANK YOU

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Presentasi Produk Biogreenscience (Apple Stem Cell)

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  • 2. COSMETICS & HEALTH FOOD IS BILLION US DOLLAR INDUSTRY!!
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  • 12. Uttwiler Spätlauber-an Apple with an Excellent Storage Ability • Storage ability of apples was an important factor to guarantee fresh fruits over winter in the 18th century • Modern apple cultivars are selected for a sweet flavour and therefore the Uttwiler Spätlauber disappeared • Today the Uttwiler Spätlauber apple is an endangered apple variety with only a few trees left in the world
  • 13. The Secret of Storage Ability • Longevityof cells • High acidand tannin concentrations • Undiscovered metabolites? Can we use this apple for skin care?
  • 14. Plant Cell Culture Technology (PCT) • PCT makes it possible to cultivate cells of endangered and rare species • The technology is based on dedifferentiated plant cells • These cells are plant stemcells and can be cultivated in liquid systems
  • 15. What are Stem Cells? • Stemcells have two properties: – Self-renewal – the ability to go through numerous cycles of cell division in an undifferentiated state – Differentiation – the capacity to differentiate into other cell types – Toti-, pluri-, multi-, unipotent stem cells
  • 16. Plant StemCells Formation of CallusTissue • If a plant is wounded, a callus tissue is formed (wound healing tissue) • In the callus tissue the normal differentiated cells go back into a dedifferentiated form and become stem cells (not possible in humans) • Mechanism is controlled by different plant hormones (auxins)
  • 18. From Callus to Plants
  • 20. Advantages of PhytoCellTecTM • Preservation of endangered plants • Use of rare plants for cosmetic applications • Growth of plant cells in-vitro • Controllable and reproducible production of metabolites • No limitation of plant sources due to seasonal restrictions
  • 27. Protect Against UV (Umbilical Cord Stem Cells)
  • 28. Growth of Hair Follicle
  • 29. Length of Hair Follicle
  • 30. PhytoCellTecTM Malus Domestica Effecton Gene Expression in Senescent DermalFibroblasts
  • 31. PhytoCellTecTM Malus Domestica Gene Profile (Microarray)
  • 34. Properties of PhytoCellTecTM • PhytoCellTecTMis a preparation of plant stem cells • PhytoCellTecTMis produced in Switzerland by a novel plant cell culture technology • PhytoCellTecTMcontains plant stem cells to protect and maintain skin stem cells • The protection of skin stem cells is a breakthrough approach in anti-aging cosmetics • Studies showed that PhytoCellTecTMprotects human stem cells and rejuvenates them • PhytoCellTecTMdelays chronological aging
  • 35. Claims • Delays senescence of essential cells • Protects longevity of skin stem cells • Protectionof skinstemcells • Rejuvenationof skin • Maintainsthepowerof regeneration • Decreasein wrinkles • Combatschronologicalaging
  • 36. Application of PhytoCellTecTM • Face care of mature skin to rejuvenate the basal layer and extend the life span of basalv keratinocytes • Face care of all age to protect the most important cells in the skin which are the stem cells • Eye serum to improve firmness and rejuvenate the extracellularmatrix • Pure PhytoCellTecTMproduct can be used as a fresh cell extract to rejuvenate the skin extensively
  • 37. Marketing Story for Costumers • PhytoCellTecTMplant stem cells are a breakthrough in anti-aging therapy • Skin stem cell treatment is a revolutionary new approach in cosmetics • Plant stem cells are extremely efficient but also safe to use • PhytoCellTecTMis based on real plant stem cells to trigger the rejuvenation of the skin • PhytoCellTecTMdelays the natural aging process by maintaining the activity of skin stem cells
  • 38. Billi Lim is the Author of No.1 International Best Selling Book "Dare To Fail" Series & The World #1 Billi Lim (chairman)
  • 39. Billi Lim, the author of the No.1 best – seller “Dare To Fail” Was born into a large family of 14. His days as a teenager, student and later in business have been checkered with lots of failures. He failed to get into the local university in his first attempt. He would have been rejected again in his second attempt had he not held a state bursary. He has failed a few times in his love life and has gone through an emotional ‘hell’.
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  • 42. artikel tentang penggunaan Stem Cell pernyataan dari Dr. Mantra Nandini, drg., SpBM(K)., MARS & Artikel yang diambil dari OKEHEALTH
  • 43. Fungsi Utama dari Sel Induk Apel Kolagen adalah sebagai berikut : 1. Memperbaiki sel yang rusak 2. Mengangtifkan sel yang tidur 3. Meregenerasi sel INFORMASI NILAI GIZI / NUTRITION FACTS : per serving 5g per serving 150g Energi 37.3kcal 1119kcal Lemak Total 0.04g 1.2g Karbohidrat Total 8.28g 248.4g Protein 0.95g 28.5g Kalsium 0 mg 0 mg
  • 44. APPLE STEAM CELL with COLLAGEN dikembangkan dari bahan bahan alami yang berkualitas serta aman. bahan tambahan seperti telir salmon, ekstrak kolagen dari salmon, dan ekstrak sari sarang burung walet, membuat produk ini sangat efektif dalam membuat anda awet muda dan meningkatkan kesehatan.