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Cells and Tissues
   Cells and Tissues
   Carry out all chemical activities needed to
    sustain life.
   Cells are the building blocks of all living
    things
   Tissues are groups of cells that are similar in
    structure and function
   Structure reflects function
   Anatomy of the Generalized Cell
   Cells are not all the same
   All cells share general structures
   Cells are organized into three main regions
   Nucleus
   Cytoplasm
   Plasma membrane
Barrier for cell
   contents
Double phospholipid
layer (fat – water)

Hydrophilic heads
Hydrophobic tails
   Other materials in
   plasma membrane
       Protein
Cholesterol
Glycoproteins
Microvilli
          Finger-like projections that
          increase surface area for
          absorption
Small intestine and nephrons of kidney
   Control center of the cell
    ◦ Contains genetic material (DNA)
   Three regions
    ◦ Nuclear membrane
    ◦ Nucleolus
    ◦ Chromatin
Barrier of nucleus
Consists of a double phospholipid membrane
Contain nuclear pores that allow for exchange of material with the rest of
the cell – selectively permeable
Nucleoli

Nucleus contains one or more nucleoli
Sites of ribosome production
Ribosomes then migrate to the cytoplasm through
nuclear pores



Chromatin (when not dividing)

   Composed of DNA and protein
   Scattered throughout the nucleus
   Chromatin condenses to form chromosomes
    when the cell divides
   Material outside the nucleus and inside the
    plasma membrane
   Cytosol
   Fluid that suspends other elements
   Organelles
   Metabolic machinery of the cell
   Inclusions
   Non-functioning units – fat, pigments…..
   Ribosomes
   Made of protein and RNA
   Sites of protein synthesis
   Found at two locations
    ◦ Free in the cytoplasm
    ◦ Attached to rough endoplasmic
      reticulum
   Endoplasmic reticulum (ER)
   Fluid-filled tubules for carrying substances
   Two types of ER
    ◦ Rough Endoplasmic Reticulum
    ◦ Studded with ribosomes
   Site where building materials of cellular membrane
    are formed
    ◦ Smooth Endoplasmic Reticulum
    ◦ Functions in cholesterol synthesis and breakdown, fat
      metabolism, and detoxification of drugs
   Golgi apparatus
   Modifies and packages proteins
   Lysosomes
   Contain enzymes that digest nonusable
    materials within the cell
   Peroxisomes
   Membranous sacs of oxidase enzymes
    ◦ Detoxify harmful substances
    ◦ Break down free radicals
      (highly reactive chemicals)
   Replicate
   Mitochondria
    ◦ “Powerhouses” of the cell
    ◦ Change shape continuously
    ◦ Carry out reactions where
      oxygen is used to break down
      food
    ◦ Provides ATP for cellular
      energy
   Cytoskeleton
    ◦ Network of protein structures that extend
      throughout the cytoplasm
    ◦ Provides the cell with an internal framework
   Cytoskeleton
   Three different types
   Microfilaments
   Intermediate
    filaments
   Microtubules
   Centrioles
   Rod-shaped bodies made of microtubules
   Direct formation of mitotic spindle during cell
    division
   Cellular Projections
   Not found in all cells
   Used for movement
    ◦ Cilia moves materials across the cell surface
    ◦ Flagellum propels the cell
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mbbs ims msu

  • 2. Cells and Tissues  Carry out all chemical activities needed to sustain life.  Cells are the building blocks of all living things  Tissues are groups of cells that are similar in structure and function  Structure reflects function
  • 3. Anatomy of the Generalized Cell  Cells are not all the same  All cells share general structures  Cells are organized into three main regions  Nucleus  Cytoplasm  Plasma membrane
  • 4. Barrier for cell contents Double phospholipid layer (fat – water) Hydrophilic heads Hydrophobic tails Other materials in plasma membrane Protein Cholesterol Glycoproteins
  • 5. Microvilli Finger-like projections that increase surface area for absorption Small intestine and nephrons of kidney
  • 6. Control center of the cell ◦ Contains genetic material (DNA)  Three regions ◦ Nuclear membrane ◦ Nucleolus ◦ Chromatin
  • 7. Barrier of nucleus Consists of a double phospholipid membrane Contain nuclear pores that allow for exchange of material with the rest of the cell – selectively permeable
  • 8. Nucleoli Nucleus contains one or more nucleoli Sites of ribosome production Ribosomes then migrate to the cytoplasm through nuclear pores Chromatin (when not dividing)  Composed of DNA and protein  Scattered throughout the nucleus  Chromatin condenses to form chromosomes when the cell divides
  • 9. Material outside the nucleus and inside the plasma membrane  Cytosol  Fluid that suspends other elements  Organelles  Metabolic machinery of the cell  Inclusions  Non-functioning units – fat, pigments…..
  • 10.
  • 11. Ribosomes  Made of protein and RNA  Sites of protein synthesis  Found at two locations ◦ Free in the cytoplasm ◦ Attached to rough endoplasmic reticulum
  • 12. Endoplasmic reticulum (ER)  Fluid-filled tubules for carrying substances  Two types of ER ◦ Rough Endoplasmic Reticulum ◦ Studded with ribosomes  Site where building materials of cellular membrane are formed ◦ Smooth Endoplasmic Reticulum ◦ Functions in cholesterol synthesis and breakdown, fat metabolism, and detoxification of drugs
  • 13. Golgi apparatus  Modifies and packages proteins
  • 14. Lysosomes  Contain enzymes that digest nonusable materials within the cell  Peroxisomes  Membranous sacs of oxidase enzymes ◦ Detoxify harmful substances ◦ Break down free radicals (highly reactive chemicals)  Replicate
  • 15. Mitochondria ◦ “Powerhouses” of the cell ◦ Change shape continuously ◦ Carry out reactions where oxygen is used to break down food ◦ Provides ATP for cellular energy
  • 16. Cytoskeleton ◦ Network of protein structures that extend throughout the cytoplasm ◦ Provides the cell with an internal framework
  • 17. Cytoskeleton  Three different types  Microfilaments  Intermediate filaments  Microtubules
  • 18. Centrioles  Rod-shaped bodies made of microtubules  Direct formation of mitotic spindle during cell division  Cellular Projections  Not found in all cells  Used for movement ◦ Cilia moves materials across the cell surface ◦ Flagellum propels the cell