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DR.AB.HALIM MANSAR
1Dr. Ab. Halim Mansar
OBJECTIVES:
- most fundamental objectives of an inquest is
to ascertain facts pertaining to the death i.e
who the dead person was, when did he die,
where did he die and how did he die?
 
-Answers to these Qs are obtained from
inquiry, post mortem examination(p.m.e)
-Deaths due to (dt) MVAs + homicide
invariably end up in a p.m.e,
in other sudden, unexpected + unnatural
deaths the body may be released without an
autopsy if there is sufficient evidence +
materials to satisfy the Coroner/ Magistrate
on the cause, manner + circumstances of
death.
2Dr. Ab. Halim Mansar
THE MEDICO-LEGAL AUTOPSIES
INQUEST
all deaths dt unnatural causes + deaths
believed to be dt natural causes but where
the medical COD is not certain / known are
subjected to an inquest.
According to Section 330 of the Criminal
Procedure Code (CPC) of Malaysia
is a preliminary inquiry conducted by a
Coroner / a Magistrate
3Dr. Ab. Halim Mansar
OBJECTIVES:
*An inquest is not a trial
-There is no complainant/ defendant + at the
conclusion of the inquest, a verdict is arrived
as to whether death was dt a natural,
accidental, suicidal/ homicidal cause
-The authority in M’sia, (the Magistrate plays
the role of the Coroner) which conducts the
inquest will order a doctor to perform a
medico-legal autopsy.
-In sudden, unnatural + violent deaths, the
police institute the inquest + executes the
power to order a p.m.e by issuing the form
Pol.61
4Dr. Ab. Halim Mansar
OBJECTIVES:
*Consent from relatives of the deceased is
not required.
-In a sudden unexpected death, only a doctor
after a p.m.e may be able to determine the
COD.
5Dr. Ab. Halim Mansar
DEATHS OCCURRING UNDER THE FOLLOWING
CIRCUMSTANCES ARE SUBJECTED TO AN INQUEST:
1. All unnatural, suspected unnatural, violent deaths, e.g
homicides
 
2. Deaths apparently from nat. causes but where the
exact medical COD is not known.
 
3. Any death caused by an accident arising out of the
use of a vehicle/ which was caused by an aircraft / rail
accident
 
4. Any death arising out of industrial employment, by
accident, industrial disease /industrial poisoning
 
5. Any death due to poisoning (alcohol intoxication,
coal gas, insecticides, barbiturates,etc)
 
6. Any death where the circumstances would seem to
indicate suicide
6Dr. Ab. Halim Mansar
7. Deaths following anaesthesia, surgery/ any
medical investigative procedure
 
8. Any death resulting from an accident in the
home, hospital/ institution/ any public place.
 
9. Any death apparently caused by neglect
(e.g.malnutrition)
10. Deaths in custody such as in police custody,
remand prison, prisons, rehabilitation centers,
detention camps etc
 
11. Deaths in mental institutions, asylums, etc.
 
12. Deaths associated with pregnancy, abortion,
childbirth etc. (maternal death)
7Dr. Ab. Halim Mansar
13. Any death of a newborn child whose body is
found
 
14. Death of a child from suffocation (including
overlaying)
 
15. Deaths of foster children
 
16. Any death as a result of a fire/ explosion
 
17. Death by drowning
 
18. Any death (occurring not in a house) where
deceased’s residence is unknown
8Dr. Ab. Halim Mansar
MALAYSIAN CRIMINAL PROCEDURE CODE (CPC)
CHAPTER 20- INQUIRIES OF DEATH
Meaning of “cause of death.”
 
328. In this Chapter the words “cause of death”
include not only the apparent COD as ascertainable
by inspection or p.m.e of the body of the deceased,
but also all matters necessary to enable an opinion
to be formed as to the manner in which the
deceased came by his death + as to whether his
death resulted in any way from, / was accelerated
by, any unlawful act / omission on the part of any
other person.
9Dr. Ab. Halim Mansar
Difficult Autopsies
Body found in water.
Body found by the road-side
Decomposed body
Skeletonised body
Body fragments
Severely charred body
Mass disaster
Anesthetic and post-operative deaths
Child deaths
Deaths in young adults
Maternal deaths.
10Dr. Ab. Halim Mansar
The Medico-Legal Autopsy. 
• Autopsy is only one part of death
investigation. Body, history
and scene are equally important. 
 Each of the three aspects of the death
investigation process are equally important.
• Scene:
-Attendance by police officers,forensic
pathologist, forensic scientist.
- The aim is to collect the maximum
information with minimum disturbance. 
- Photography,videos,trace evidence
11Dr. Ab. Halim Mansar
History: 
-Social- from relatives,friends,police. 
-Medical-from GP,hospital notes. Often
indicates the likely cause of death. 
-Psychiatric-from GP,hospital notes. May
indicate possibility of suicide.
- Autopsy authority: 
 
 -Police or Coroner(Magistrate).
- “Police 61” form(Permintaan Pemeriksaan
Mayat).
12Dr. Ab. Halim Mansar
Identification
 Visual(relatives).
Circumstantial(address,car,papers,cards,key
s,cloths).
 Medical( scars,teeth,x-rays,DNA).
 Fingerprint.
13Dr. Ab. Halim Mansar
Personal effects and clothing 
By contrast with the hospital autopsy, the examination
of personal effects and clothing is an integral part of
the medico-legal autopsy providing information on life
style, events leading to death, and often the actual
cause of death.
Clothing findings are correlated with historical and
scene information, e.g. appropriateness of clothing,
source of stains, trace materials. Clothing findings
must also be correlated with other autopsy data, e.g.
injuries, source of blood stains. 
14Dr. Ab. Halim Mansar
External Examination
-This is a detailed head to toe examination
of a naked body, documenting stains and
soiling, general and specific individualising
 characteristics,postmortem
changes(temperature,lividity,rigor
mortis,putrefaction).
-The location, extent and type of staining or
soiling of the body are described.
15Dr. Ab. Halim Mansar
Injuries
All injuries are described systematically either
by grouping them according to anatomical
location or in numerical order.
 Injuries are described as to their type, (bruise,
abrasion laceration,incised wound,puncture of
stab wound,gunshot wound,burn,fracture),
location,size,shape and colour.
Internal injuries are described in continuity
with the related externally apparent injuries.
Old injuries are segregated from recent
injuries.
16Dr. Ab. Halim Mansar
- Signs of medical intervention.
-Medical intervention is described under a
separate heading. This includes all medical
equipment attached to,or accompanying the
body.
-External surgical incisions are described in
continuity with internal evidence of surgery.
17Dr. Ab. Halim Mansar
Internal examination
The internal examination is systematic description
of natural disease and recent injuries. Negative
observations are included,e.g. no pulmonary
thrombo-emboli,no significant coronary
atherosclerosis,etc.
18Dr. Ab. Halim Mansar
Other examinations
-Any special dissections,(neck dissection),or further
examination of organs(brain after formalin fixation),
together with microscopic, biochemical and
toxicological studies shoulder also be described.
Definition
-Mechanism of death: the physiological or biochemical
derangement produced by the above cause, which is
incompatible with life: i.e. how the disease or injury
leads to death.
-Manner of death: explains how the cause of death came
about : I.e. whether natural, accident, suicide, homicide
or undetermined/unascertained. The manner of death
as determined by the forensic pathologist is an opinion
based on the facts concerning the circumstances leading
up to and surrounding the death in conjunction with the
findings at autopsy and the laboratory tests.
19Dr. Ab. Halim Mansar
SUDDEN AND UNEXPECTED
NATURAL DEATH
Although from the description above given a natural
death cause no obvious criminal or accidental, it
nevertheless becomes of some concern to the forensic
pathologist simply because of the difficulty or even
impossibility to furnish a certifiable cause of death
The numerous causes of sudden natural death may
conveniently be classified according to the different
anatomical systems of the body.
20Dr. Ab. Halim Mansar
Definition
- Death within 24 hrs from onset of symptoms
- Some accepts : death within 1 hrs of onset of symptoms
- An unexpected witnessed death (nat. causes wit/out preexisty
disease than occurs within 6 hrs of onset of symptoms
- Cor. Heart Disease > 75 % of sudden Cardiac Deaths
other Cardiac conditions : = 20 % of cases
COD remains unknown : 1 – 2 % of cases
21Dr. Ab. Halim Mansar
Cardiovascular System
Deaths resulting from diseases and disorders of the
circulatory system account for the vast majority of
sudden natural deaths.
They are considered under diseases of the vessels, the
heart muscles and the heart valves.
In some cases there is an overlap from one system to
another.
22Dr. Ab. Halim Mansar
Ischemic heart disease
Interruption or interference with the blood flow to the
heart along the coronary arteries will have profound
effects on the heart itself
In the extreme-the heart will suddenly cease functioning
In less extreme, areas of the heart will fail which in turn
causes a chain reaction and finally the complete heart
failure.
At autopsy, one or more of the main branches of the
two coronary arteries may show of severe disease
process. There will be a deposition of soft white or
yellow necrotic fatty material on the lining of the arteries
23Dr. Ab. Halim Mansar
Hypertensive Heart Disease
An enlargement of the left ventricle of the heart with
accompanying increase in the thickness of the muscle wall will
result in a raise blood pressure, frequently to a level twice as
high as normal.
So that, rupture of vessels is frequently seen in the presence
of hypertension – raised blood pressure. Example: rupture of
a cerebral artery.
The cardiac enlargement almost limited to the left ventricle,
the three remaining usually within normal size.
In many cases the cause for cardiac enlargement is unknown,
when the term primary or essential hypertension is used.
24Dr. Ab. Halim Mansar
Death occurs quite suddenly and unexpectedly.
There may be an incident of exertion, anger, emotion
and stress but equally the death may follow a period of
rest.
One reason for a sudden collapse and death is that the
mass of heart muscle has outstripped its own blood
supply.
25Dr. Ab. Halim Mansar
Aortic Valve disease
Sudden death result because of the hyperthrophied left
ventricle to force the blood through the diseased and
narrowed valve.
An alternative reason is that the disease process may
spread out from the valve and impede the entry of blood
into the ostia of the nearby coronary arteries.
26Dr. Ab. Halim Mansar
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31Dr. Ab. Halim Mansar
RESPIRATORY SYSTEM
The main causes are massive haemorrhage in the air
passages, pneumothorax, infections and asthma.
32Dr. Ab. Halim Mansar
Haemorrhage in the Air
Passages
When a massive haemorrhage occurs into the major air
passages death results from an obstruction to normal
respiratory gaseous exchange.
Erosion of a large pulmonary vessel by a malignant tumor
or by an expanding pulmonary infection.
Example: Tuberculosis, produces a massive bleed and
death follows very shortly
In former years the frequency of syphilitic aortic
aneurysms in the thorax means that many would erode
into a bronchus leading to a rapid death
33Dr. Ab. Halim Mansar
Pneumothorax
The spontaneous rupture of an emphysematous bulla on
the periphery of a lung. e.g.: following a bout of coughing
or straining during some physical exertion, can be lead to
a massive escape of air into one of the pleural cavities.
The vacuum normally present is lost and there is an
immediate collapse of the affected lung.
In the absence of special medical equipment death may
rapidly ensue, especially if there is concomitant disease in
the other lung in the heart.
34Dr. Ab. Halim Mansar
Infections
Whilst most chest and lung infections can produce a
severe illness which may lead on slowly to death, there
are few bacterial and viral infections, which can produce
sudden and unexpected deaths in very short time
Example1: a sports master at large school used to spend
his lunchtime break playing indoor football with some of
the other teacher before returning to their classes for
the afternoon. After a quarter of an hour the game
finished and the member of staff went to the changing
room to find the sports master dead on bench.
35Dr. Ab. Halim Mansar
Example 2: A young man, shortly to be married, was
decorating his future home one evening after a day’s work
along with his father. The young man said that he had some
tightness across his chest and that he would not continue
painting. His father completed what he was doing and joined
his son in another room 20 minutes later, where he found him
dead.
In both these cases, there was an acute hemorrhagic
bronchopneumonia.- Culture and virological studies showed a
florid viral infection.
Chronic bronchitis can also on occasions cause a sudden
death.
36Dr. Ab. Halim Mansar
Asthma
Asthma is the sudden and prolonged spasm of the
smooth muscles in the walls of bronchioles.
The bronchospasm causes sever constriction of the air
passages.
In the case, the death is due to respiratory failure in the
exchange of oxygen and carbon dioxide within the lungs.
This may due to obstruction in the airways, restriction in
the ability to expand the lungs, allergic neuromuscular
problems and ventilation abnormalities.
37Dr. Ab. Halim Mansar
38Dr. Ab. Halim Mansar
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40Dr. Ab. Halim Mansar
41Dr. Ab. Halim Mansar
CENTRAL NERVOUS SYSTEM
Nearly always caused by hemorrhage which may occur
either within the brain, or outside within the meninges
42Dr. Ab. Halim Mansar
Cerebral Haemorrhage
This is often referred to as cerebrovascular accident,
although the word accident is a msnomer
The massive bleed usually occurs either within the basal
ganglia or more distally in the internal capsule.
The hemorrhage is associated with raised blood
pressure, so that the victim is usually an elderly person
with hypertensive heart disease and widespread
arteriosclerosis, especially of the cerebral arteries.
May also occur in other sites such as pons or the
cerebellum but they are much less frequently seen.
43Dr. Ab. Halim Mansar
Circulatory, non-hemorrhagic
causes
The formation of a cerebral thrombus in one of the
cerebral arteries at the base of the brain, or in a smaller
within the brain may cause loss of consciousness leading
to death within a short time. The thrombus is usually
formed in association with a localized plaque of
arteriosclerosis.
A most unusual cause is that of a cerebral embolus,
which may arise from an area of thrombus formation
within the cavity of the heart, passing upwards to the
brain via one of the carotid arteries.
44Dr. Ab. Halim Mansar
Epilepsy
Epileptic sufferers may die during a prolonged single
seizure or more usually during a series of repeated
seizures termed status epilepticus
Death is due to asphyxia if the epileptis ceases to breathe
or aspirates regurgitated vomit, or has an airway
obstructed by the tongue.
45Dr. Ab. Halim Mansar
46Dr. Ab. Halim Mansar
GASTROINTESTINAL SYSTEM
A Massive bleed may occur when a gastric or duodenal ulcer
erodes through the sub mucosal tissues and into an artery
lying close by.
The profuse bleeding may pass down the intestinal tract
emerging from the anus, or it may enter the stomach and be
vomited up, or more frequently it will pass in both directions.
Another form of dramatic fatal bleeding occurs when varicose
and distended veins at the lower end of the esophagus
become eroded and burst. This usually occurs in a patient
who had developed severe fatty change or even cirrhosis of
the liver brought about by chronic alcohol use.
47Dr. Ab. Halim Mansar
Fatty change to the liver can also produce a sudden
death but the exact mechanism remains unknown.
In some cases there is microscopic evidence of fat
embolization to the lungs or even the heart or brain.
Equally there may be a sudden disturbance to the nearby
pancreas and insulin activity.
48Dr. Ab. Halim Mansar
OTHER SYSTEMS
In pregnancy, sudden deaths are usually associated with
haemorrhage.
The rupture of an extra-uterine pregnancy may produce a
massive intra-abdominal haemorrhage which on occasions
has caused death.
Premature separation of a placenta previa may both cause
severe exsanguinations unless there is medical aid.
Attempts at abortion by inexpert persons may cause death
either by perforation by the instrument of a major vessel,
or by causing pulmonary embolus by means of air, chemical
fluids or the release of amniotic fluid into the blood stream.
49Dr. Ab. Halim Mansar
The adrenal gland may be a related to a sudden death as
a result of bilateral adrenal haemorrhage produced during
a meningococcal septicemia
Usually, there is evidence of the bacterial infection
elsewhere followed by adrenal collapse and death.
50Dr. Ab. Halim Mansar
SUDDEN DEATH FROM
UNKNOWN CAUSES
There is nothing more frustrating and no case remains so
memorable, than a death for which there is no
demonstrable cause
All pathologists of cases where, after autopsy, toxicology,
bacteriology, virology, histology and a review of the
history of the case with all the professional concerned,
there is no reasonable cause to be found.
One very special group of deaths which still remains a
mystery is the sudden death in infancy syndrome.
51Dr. Ab. Halim Mansar
These deaths invite further research into their causation:
1. reflex cardiac deaths during or following minor surgical or
medical procedures
2. the strange deaths of apparently fit and healthy young
persons during some sport or game
3. on a worldwide scale the deaths of healthy persons who
have been cursed to die.
52Dr. Ab. Halim Mansar
Thank you
53Dr. Ab. Halim Mansar

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Forensic medicine natural death

  • 2. OBJECTIVES: - most fundamental objectives of an inquest is to ascertain facts pertaining to the death i.e who the dead person was, when did he die, where did he die and how did he die?   -Answers to these Qs are obtained from inquiry, post mortem examination(p.m.e) -Deaths due to (dt) MVAs + homicide invariably end up in a p.m.e, in other sudden, unexpected + unnatural deaths the body may be released without an autopsy if there is sufficient evidence + materials to satisfy the Coroner/ Magistrate on the cause, manner + circumstances of death. 2Dr. Ab. Halim Mansar
  • 3. THE MEDICO-LEGAL AUTOPSIES INQUEST all deaths dt unnatural causes + deaths believed to be dt natural causes but where the medical COD is not certain / known are subjected to an inquest. According to Section 330 of the Criminal Procedure Code (CPC) of Malaysia is a preliminary inquiry conducted by a Coroner / a Magistrate 3Dr. Ab. Halim Mansar
  • 4. OBJECTIVES: *An inquest is not a trial -There is no complainant/ defendant + at the conclusion of the inquest, a verdict is arrived as to whether death was dt a natural, accidental, suicidal/ homicidal cause -The authority in M’sia, (the Magistrate plays the role of the Coroner) which conducts the inquest will order a doctor to perform a medico-legal autopsy. -In sudden, unnatural + violent deaths, the police institute the inquest + executes the power to order a p.m.e by issuing the form Pol.61 4Dr. Ab. Halim Mansar
  • 5. OBJECTIVES: *Consent from relatives of the deceased is not required. -In a sudden unexpected death, only a doctor after a p.m.e may be able to determine the COD. 5Dr. Ab. Halim Mansar
  • 6. DEATHS OCCURRING UNDER THE FOLLOWING CIRCUMSTANCES ARE SUBJECTED TO AN INQUEST: 1. All unnatural, suspected unnatural, violent deaths, e.g homicides   2. Deaths apparently from nat. causes but where the exact medical COD is not known.   3. Any death caused by an accident arising out of the use of a vehicle/ which was caused by an aircraft / rail accident   4. Any death arising out of industrial employment, by accident, industrial disease /industrial poisoning   5. Any death due to poisoning (alcohol intoxication, coal gas, insecticides, barbiturates,etc)   6. Any death where the circumstances would seem to indicate suicide 6Dr. Ab. Halim Mansar
  • 7. 7. Deaths following anaesthesia, surgery/ any medical investigative procedure   8. Any death resulting from an accident in the home, hospital/ institution/ any public place.   9. Any death apparently caused by neglect (e.g.malnutrition) 10. Deaths in custody such as in police custody, remand prison, prisons, rehabilitation centers, detention camps etc   11. Deaths in mental institutions, asylums, etc.   12. Deaths associated with pregnancy, abortion, childbirth etc. (maternal death) 7Dr. Ab. Halim Mansar
  • 8. 13. Any death of a newborn child whose body is found   14. Death of a child from suffocation (including overlaying)   15. Deaths of foster children   16. Any death as a result of a fire/ explosion   17. Death by drowning   18. Any death (occurring not in a house) where deceased’s residence is unknown 8Dr. Ab. Halim Mansar
  • 9. MALAYSIAN CRIMINAL PROCEDURE CODE (CPC) CHAPTER 20- INQUIRIES OF DEATH Meaning of “cause of death.”   328. In this Chapter the words “cause of death” include not only the apparent COD as ascertainable by inspection or p.m.e of the body of the deceased, but also all matters necessary to enable an opinion to be formed as to the manner in which the deceased came by his death + as to whether his death resulted in any way from, / was accelerated by, any unlawful act / omission on the part of any other person. 9Dr. Ab. Halim Mansar
  • 10. Difficult Autopsies Body found in water. Body found by the road-side Decomposed body Skeletonised body Body fragments Severely charred body Mass disaster Anesthetic and post-operative deaths Child deaths Deaths in young adults Maternal deaths. 10Dr. Ab. Halim Mansar
  • 11. The Medico-Legal Autopsy.  • Autopsy is only one part of death investigation. Body, history and scene are equally important.   Each of the three aspects of the death investigation process are equally important. • Scene: -Attendance by police officers,forensic pathologist, forensic scientist. - The aim is to collect the maximum information with minimum disturbance.  - Photography,videos,trace evidence 11Dr. Ab. Halim Mansar
  • 12. History:  -Social- from relatives,friends,police.  -Medical-from GP,hospital notes. Often indicates the likely cause of death.  -Psychiatric-from GP,hospital notes. May indicate possibility of suicide. - Autopsy authority:     -Police or Coroner(Magistrate). - “Police 61” form(Permintaan Pemeriksaan Mayat). 12Dr. Ab. Halim Mansar
  • 14. Personal effects and clothing  By contrast with the hospital autopsy, the examination of personal effects and clothing is an integral part of the medico-legal autopsy providing information on life style, events leading to death, and often the actual cause of death. Clothing findings are correlated with historical and scene information, e.g. appropriateness of clothing, source of stains, trace materials. Clothing findings must also be correlated with other autopsy data, e.g. injuries, source of blood stains.  14Dr. Ab. Halim Mansar
  • 15. External Examination -This is a detailed head to toe examination of a naked body, documenting stains and soiling, general and specific individualising  characteristics,postmortem changes(temperature,lividity,rigor mortis,putrefaction). -The location, extent and type of staining or soiling of the body are described. 15Dr. Ab. Halim Mansar
  • 16. Injuries All injuries are described systematically either by grouping them according to anatomical location or in numerical order.  Injuries are described as to their type, (bruise, abrasion laceration,incised wound,puncture of stab wound,gunshot wound,burn,fracture), location,size,shape and colour. Internal injuries are described in continuity with the related externally apparent injuries. Old injuries are segregated from recent injuries. 16Dr. Ab. Halim Mansar
  • 17. - Signs of medical intervention. -Medical intervention is described under a separate heading. This includes all medical equipment attached to,or accompanying the body. -External surgical incisions are described in continuity with internal evidence of surgery. 17Dr. Ab. Halim Mansar
  • 18. Internal examination The internal examination is systematic description of natural disease and recent injuries. Negative observations are included,e.g. no pulmonary thrombo-emboli,no significant coronary atherosclerosis,etc. 18Dr. Ab. Halim Mansar
  • 19. Other examinations -Any special dissections,(neck dissection),or further examination of organs(brain after formalin fixation), together with microscopic, biochemical and toxicological studies shoulder also be described. Definition -Mechanism of death: the physiological or biochemical derangement produced by the above cause, which is incompatible with life: i.e. how the disease or injury leads to death. -Manner of death: explains how the cause of death came about : I.e. whether natural, accident, suicide, homicide or undetermined/unascertained. The manner of death as determined by the forensic pathologist is an opinion based on the facts concerning the circumstances leading up to and surrounding the death in conjunction with the findings at autopsy and the laboratory tests. 19Dr. Ab. Halim Mansar
  • 20. SUDDEN AND UNEXPECTED NATURAL DEATH Although from the description above given a natural death cause no obvious criminal or accidental, it nevertheless becomes of some concern to the forensic pathologist simply because of the difficulty or even impossibility to furnish a certifiable cause of death The numerous causes of sudden natural death may conveniently be classified according to the different anatomical systems of the body. 20Dr. Ab. Halim Mansar
  • 21. Definition - Death within 24 hrs from onset of symptoms - Some accepts : death within 1 hrs of onset of symptoms - An unexpected witnessed death (nat. causes wit/out preexisty disease than occurs within 6 hrs of onset of symptoms - Cor. Heart Disease > 75 % of sudden Cardiac Deaths other Cardiac conditions : = 20 % of cases COD remains unknown : 1 – 2 % of cases 21Dr. Ab. Halim Mansar
  • 22. Cardiovascular System Deaths resulting from diseases and disorders of the circulatory system account for the vast majority of sudden natural deaths. They are considered under diseases of the vessels, the heart muscles and the heart valves. In some cases there is an overlap from one system to another. 22Dr. Ab. Halim Mansar
  • 23. Ischemic heart disease Interruption or interference with the blood flow to the heart along the coronary arteries will have profound effects on the heart itself In the extreme-the heart will suddenly cease functioning In less extreme, areas of the heart will fail which in turn causes a chain reaction and finally the complete heart failure. At autopsy, one or more of the main branches of the two coronary arteries may show of severe disease process. There will be a deposition of soft white or yellow necrotic fatty material on the lining of the arteries 23Dr. Ab. Halim Mansar
  • 24. Hypertensive Heart Disease An enlargement of the left ventricle of the heart with accompanying increase in the thickness of the muscle wall will result in a raise blood pressure, frequently to a level twice as high as normal. So that, rupture of vessels is frequently seen in the presence of hypertension – raised blood pressure. Example: rupture of a cerebral artery. The cardiac enlargement almost limited to the left ventricle, the three remaining usually within normal size. In many cases the cause for cardiac enlargement is unknown, when the term primary or essential hypertension is used. 24Dr. Ab. Halim Mansar
  • 25. Death occurs quite suddenly and unexpectedly. There may be an incident of exertion, anger, emotion and stress but equally the death may follow a period of rest. One reason for a sudden collapse and death is that the mass of heart muscle has outstripped its own blood supply. 25Dr. Ab. Halim Mansar
  • 26. Aortic Valve disease Sudden death result because of the hyperthrophied left ventricle to force the blood through the diseased and narrowed valve. An alternative reason is that the disease process may spread out from the valve and impede the entry of blood into the ostia of the nearby coronary arteries. 26Dr. Ab. Halim Mansar
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  • 32. RESPIRATORY SYSTEM The main causes are massive haemorrhage in the air passages, pneumothorax, infections and asthma. 32Dr. Ab. Halim Mansar
  • 33. Haemorrhage in the Air Passages When a massive haemorrhage occurs into the major air passages death results from an obstruction to normal respiratory gaseous exchange. Erosion of a large pulmonary vessel by a malignant tumor or by an expanding pulmonary infection. Example: Tuberculosis, produces a massive bleed and death follows very shortly In former years the frequency of syphilitic aortic aneurysms in the thorax means that many would erode into a bronchus leading to a rapid death 33Dr. Ab. Halim Mansar
  • 34. Pneumothorax The spontaneous rupture of an emphysematous bulla on the periphery of a lung. e.g.: following a bout of coughing or straining during some physical exertion, can be lead to a massive escape of air into one of the pleural cavities. The vacuum normally present is lost and there is an immediate collapse of the affected lung. In the absence of special medical equipment death may rapidly ensue, especially if there is concomitant disease in the other lung in the heart. 34Dr. Ab. Halim Mansar
  • 35. Infections Whilst most chest and lung infections can produce a severe illness which may lead on slowly to death, there are few bacterial and viral infections, which can produce sudden and unexpected deaths in very short time Example1: a sports master at large school used to spend his lunchtime break playing indoor football with some of the other teacher before returning to their classes for the afternoon. After a quarter of an hour the game finished and the member of staff went to the changing room to find the sports master dead on bench. 35Dr. Ab. Halim Mansar
  • 36. Example 2: A young man, shortly to be married, was decorating his future home one evening after a day’s work along with his father. The young man said that he had some tightness across his chest and that he would not continue painting. His father completed what he was doing and joined his son in another room 20 minutes later, where he found him dead. In both these cases, there was an acute hemorrhagic bronchopneumonia.- Culture and virological studies showed a florid viral infection. Chronic bronchitis can also on occasions cause a sudden death. 36Dr. Ab. Halim Mansar
  • 37. Asthma Asthma is the sudden and prolonged spasm of the smooth muscles in the walls of bronchioles. The bronchospasm causes sever constriction of the air passages. In the case, the death is due to respiratory failure in the exchange of oxygen and carbon dioxide within the lungs. This may due to obstruction in the airways, restriction in the ability to expand the lungs, allergic neuromuscular problems and ventilation abnormalities. 37Dr. Ab. Halim Mansar
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  • 42. CENTRAL NERVOUS SYSTEM Nearly always caused by hemorrhage which may occur either within the brain, or outside within the meninges 42Dr. Ab. Halim Mansar
  • 43. Cerebral Haemorrhage This is often referred to as cerebrovascular accident, although the word accident is a msnomer The massive bleed usually occurs either within the basal ganglia or more distally in the internal capsule. The hemorrhage is associated with raised blood pressure, so that the victim is usually an elderly person with hypertensive heart disease and widespread arteriosclerosis, especially of the cerebral arteries. May also occur in other sites such as pons or the cerebellum but they are much less frequently seen. 43Dr. Ab. Halim Mansar
  • 44. Circulatory, non-hemorrhagic causes The formation of a cerebral thrombus in one of the cerebral arteries at the base of the brain, or in a smaller within the brain may cause loss of consciousness leading to death within a short time. The thrombus is usually formed in association with a localized plaque of arteriosclerosis. A most unusual cause is that of a cerebral embolus, which may arise from an area of thrombus formation within the cavity of the heart, passing upwards to the brain via one of the carotid arteries. 44Dr. Ab. Halim Mansar
  • 45. Epilepsy Epileptic sufferers may die during a prolonged single seizure or more usually during a series of repeated seizures termed status epilepticus Death is due to asphyxia if the epileptis ceases to breathe or aspirates regurgitated vomit, or has an airway obstructed by the tongue. 45Dr. Ab. Halim Mansar
  • 46. 46Dr. Ab. Halim Mansar
  • 47. GASTROINTESTINAL SYSTEM A Massive bleed may occur when a gastric or duodenal ulcer erodes through the sub mucosal tissues and into an artery lying close by. The profuse bleeding may pass down the intestinal tract emerging from the anus, or it may enter the stomach and be vomited up, or more frequently it will pass in both directions. Another form of dramatic fatal bleeding occurs when varicose and distended veins at the lower end of the esophagus become eroded and burst. This usually occurs in a patient who had developed severe fatty change or even cirrhosis of the liver brought about by chronic alcohol use. 47Dr. Ab. Halim Mansar
  • 48. Fatty change to the liver can also produce a sudden death but the exact mechanism remains unknown. In some cases there is microscopic evidence of fat embolization to the lungs or even the heart or brain. Equally there may be a sudden disturbance to the nearby pancreas and insulin activity. 48Dr. Ab. Halim Mansar
  • 49. OTHER SYSTEMS In pregnancy, sudden deaths are usually associated with haemorrhage. The rupture of an extra-uterine pregnancy may produce a massive intra-abdominal haemorrhage which on occasions has caused death. Premature separation of a placenta previa may both cause severe exsanguinations unless there is medical aid. Attempts at abortion by inexpert persons may cause death either by perforation by the instrument of a major vessel, or by causing pulmonary embolus by means of air, chemical fluids or the release of amniotic fluid into the blood stream. 49Dr. Ab. Halim Mansar
  • 50. The adrenal gland may be a related to a sudden death as a result of bilateral adrenal haemorrhage produced during a meningococcal septicemia Usually, there is evidence of the bacterial infection elsewhere followed by adrenal collapse and death. 50Dr. Ab. Halim Mansar
  • 51. SUDDEN DEATH FROM UNKNOWN CAUSES There is nothing more frustrating and no case remains so memorable, than a death for which there is no demonstrable cause All pathologists of cases where, after autopsy, toxicology, bacteriology, virology, histology and a review of the history of the case with all the professional concerned, there is no reasonable cause to be found. One very special group of deaths which still remains a mystery is the sudden death in infancy syndrome. 51Dr. Ab. Halim Mansar
  • 52. These deaths invite further research into their causation: 1. reflex cardiac deaths during or following minor surgical or medical procedures 2. the strange deaths of apparently fit and healthy young persons during some sport or game 3. on a worldwide scale the deaths of healthy persons who have been cursed to die. 52Dr. Ab. Halim Mansar
  • 53. Thank you 53Dr. Ab. Halim Mansar