Incretin based therapy of type 2 diabetes mellitus 1

Incretin Based Therapy of Type 2 Diabetes Mellitus BY Prof. ADEL A EL-SAYED MD Prof. of Internal Medicine Sohag Faculty of Medicine SOHAG EGYPT

Pathophysiology of Type 2 Diabetes ,[object Object],[object Object]

Pathophysiology of Type 2 Diabetes Insulin Resistance ,[object Object],[object Object]

Pathophysiology of Type 2 Diabetes Beta cell defect ,[object Object],[object Object],[object Object]

Pathophysiology of Type 2 Diabetes Beta cell defect ,[object Object],[object Object]

Pathophysiology of Type 2 Diabetes Other Factors ,[object Object],[object Object]

Pathophysiology of Type 2 Diabetes Other Factors ,[object Object],[object Object],[object Object]

Pathophysiology of Type 2 Diabetes The Glucagon Factor ,[object Object],[object Object],[object Object]

Pathophysiology of Type 2 Diabetes The Glucagon Factor ,[object Object],[object Object],[object Object],[object Object]

Pathophysiology of Type 2 Diabetes The Gastric Emptying Factor ,[object Object],[object Object],[object Object]

Pathophysiology of Type 2 Diabetes One last observation ,[object Object],[object Object],[object Object],[object Object]

What are incretins? ,[object Object],[object Object],[object Object]

What are incretins? Gastric Inhibitory Polypeptide (GIP) ,[object Object]

What are incretins? Glucagon-like peptide-1 (GLP-1) ,[object Object],[object Object],[object Object]

Actions of GLP-1 ,[object Object],[object Object],[object Object],[object Object],[object Object]

Actions of GLP-1 ,[object Object],[object Object],[object Object],[object Object]

Actions of GLP-1 ,[object Object]

Actions of GLP-1 The Problem ,[object Object]

The solution ,[object Object],[object Object],[object Object]

Incretin mimetics Exenatide ,[object Object],[object Object],[object Object],[object Object]

Incretin mimetics Exenatide ,[object Object],[object Object],[object Object]

Clinical Trials of Exenatide ,[object Object],[object Object],[object Object]

Weight Loss With Exenatide ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Nausea With Exenatide ,[object Object],[object Object]

Incretin mimetics Recent Advances ,[object Object],[object Object]

Dipeptidyl Peptidase-IV Antagonists ,[object Object],[object Object],[object Object],[object Object],[object Object]

Dipeptidyl Peptidase-IV Antagonists Sitagliptin and Vildagliptin ,[object Object],[object Object],[object Object],[object Object]

Dipeptidyl Peptidase-IV Antagonists Recent Advances ,[object Object],[object Object]

Summary ,[object Object],[object Object],[object Object],[object Object],[object Object]

Summary ,[object Object],[object Object],[object Object]

Summary ,[object Object],[object Object],[object Object],[object Object]

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