MRCPsych08 - How To Analyse Diagnostic Test Studies (June08)

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This is an educational talk/presentation on the science of diagnostic tests using examples from psychiatry. It was first presented for MRCPsych (Royal College of Psychiatrists UK) June 2008. Now updated in 2009...see newer version

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MRCPsych Teaching 2008

Critical Appraisal of Diagnostic Test Studies

Alex J Mitchell
Consultant in Liaison Psychiatry
University of Leicester

Contents
• Importance of understanding diagnostic tests

• Statistics of diagnostic validity

• Examples

Importance of understanding diagnostic tests

What Is a Diagnostic Test in Psychiatry?
• CT/MRI
• CSF
• Blood tests eg TFTs
• SCAN/SCID/PSE/MINI
• Neuropsychological Testing
• MMSE
• HADS/BDI/CESD?
• Clinical Judgement
• Self-report

Why Is a HADS score not a diagnosis?

1. No core features
2. No symptom ranking
3. No functional assessment
4. Duration unclear
5. What if Missing items?
6. Imprecise

MRCPsych08 - How To Analyse Diagnostic Test Studies (June08)

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