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Diagnosis and Management of
 Hemorrhage in Oral Surgery




    DR MOHAMMAD AKHEEL
        OMFS PG
What is meant by Hemorrhage ?


Prolonged or uncontrolled bleeding is often
referred to as hemorrhage.

The amount of blood lost as a result of
hemorrhage can range from minimal to
significant quantities.
Hemorrhage in Surgery



Hemorrhage can occur to a greater or lesser
degree during all surgical procedures and it’s
management depends upon whether the patient is
hematologically normal or suffers from some
disturbance in the normal clotting mechanism.
Hemorrhage in Oral Surgery
Hemorrhage in Oral Surgery


The overwhelming majority of patients who
undergo oral surgical procedures are those who
have normal haemostatic mechanism.

Therefore, significant or major hemorrhages are
not that common in oral surgery except in patients
who have a bleeding / clotting disorder or those
who are on anticoagulants.
Hemorrhage in Oral Surgery


However, uncontrolled and persistent bleeding
can occur in some healthy patients after dental
extraction.

Therefore, it is still important to achieve proper
hemostasis in all patients during oral surgical
procedures, so as to prevent excessive post-
operative blood loss.
Normal Mechanism of Hemostasis



Hemostasis is a complicated process.

It involves a number of events
Hemostasis - Normal Mechanism


1. VASCULAR PHASE

2. PLATELET PHASE

3. COAGULATION PHASE
VASCULAR PHASE




When a blood vessel is damaged,
vasoconstriction results.
PLATELET PHASE


Platelets adhere to the damaged surface
                  and
      form a temporary plug.
COAGULATION PHASE



Through two separate pathways, the
Intrinsic and Extrinsic, the conversion of
fibrinogen to fibrin is complete. Fibrin
tightly binds the platelets to form a clot
THE CLOTTING MECHANISM

 INTRINSIC             EXTRINSIC
  Collagen     Tissue Thromboplastin
  XII
    XI                   VII
      IX
        VIII

                   X

               V                       FIBRINOGEN
                                             (I)

PROTHROMBIN            THROMBIN
    (II)                  (III)        FIBRIN
HEMOSTASIS
DEPENDENT UPON:

 Vessel Wall Integrity

 Adequate Numbers of Platelets

 Proper Functioning Platelets

 Adequate Levels of Clotting Factors

 Proper Function of Fibrinolytic Pathway
Hemorrhage in Oral Surgery


Hemorrhage following Oral Surgical procedures
can occur due to local or systemic causes.

In healthy patients the postoperative bleeding is
mainly due to local causes.
Local causes of hemorrhage in oral surgery




Local causes of hemorrhage originate in either
soft tissue or bone.
Local causes of hemorrhage in oral surgery –
                Soft tissue bleeding



 Soft tissue bleeding is either arterial, venous, or
 capillary in nature.
Local causes - Soft tissue bleeding in oral surgery



 Arterial bleeding is bright red and spurting in nature.

 Arteries in the soft tissues at risk during oral surgical
 procedures are the lies posterior portion of hard palate)
 greater palatine artery and the buccal artery (lies lateral
 to the retromolar pad)
Local causes - Soft tissue bleeding in oral surgery



 Venous blood is dark red in color and flows
 steadily and heavily especially if the vein is large .

 Capillary bleeding is bright red in color and is
 more of a minimal ooze.
Local causes – Osseous (Bony) bleeding in oral
                    surgery



Troublesome bone bleeding originates either from
nutrient canals in the alveolar region, central
vessels, such as the inferior alveolar artery, or
from central vascular lesions (Hemangioma or
Vascular malformation)
Systemic causes of hemorrhage in oral surgery


 Some patients with heriditary conditions such as
 hemophilia, Von Willebrand’s disease are susceptible for
 hemorrhage following oral surgical procedures.

 Patients with thrombocytopenia (decreased platelet
 count) , Leukemia e.t.c., are also at risk of prolonged
 bleeding after surgery.

 Patients with uncontrolled hypertension.
Systemic causes of hemorrhage in oral surgery


 Patients with H/O prosthetic heart valve replacement,
 Stroke (Cerebrovascular accident) e.t.c., take oral
 anticoagulants like Aspirin or Warfarin to prevent the
 occurrence of a thromboembolic episode.

 These patients are also at risk of prolonged severe
 bleeding during and after an oral surgical procedure.
Types of Hemorrhage - Primary Hemorrhage

This occurs during the surgery, as a result of injury like
cutting or laceration of the artery or bleeding from
bone.

This also occurs when surgery is done in an infected
area with a lot of granulation tissue.

It can also occur after a very short period of time
immediately after surgery.

This type of bleeding is really normal and can be
controlled easily.
Types of Hemorrhage - Intermediate /
             Reactionary Hemorrhage


This type of bleeding occurs within a few hours after
surgery.

This type of bleeding occurs as a result of failure of
coagulation to occur (as in patients with systemic
bleeding problems or those on anticoagulants)

Patients who have unknowingly disturbed / dislodged the
clot are also prone for this type of bleeding.
Types of Hemorrhage - Secondary Hemorrhage



 This occurs after 7 to 10 days after surgery. This is
 mainly due to partial division of blood vessel in
 combination with infection of the wound (Like patient’s
 who undergo radical neck dissection e.t.c.,).

 This type of bleeding is not very frequently encountered
 after oral surgery procedures.
Management of Primary Hemorrhage in Normal
                          patients

        The management of bleeding during surgery (Primary
         bleeding) can be achieved by the following means,

(i)     Securing / ligation of blood vessels with silk sutures.
(ii)    Use of pressure swab to achieve hemostasis.
(iii)   Use of electrocautery to achieve hemostasis.
(iv)    Use of hemostatic agents like bone wax, surgicel,e.t.c.,
(v)     Hypotensive anaesthesia (G.A) and use of
        vasoconstrictors in L.A.
Local Measures ( Synthetic Materials)



There are several materials that are commercially
available that are used locally for achieving
adequate hemostasis.
Local Measures: Surgicel (Oxidised Regenerated
                  Cellulose)
Local measures: Gelfoam with activated thrombin
Local Measures: Avitene (Microfibrillar
               Collagen)
Local Measures:
Etik Collagen (Packed collagen)
Local Measures: Tranexamic acid 5%
Local Measures: Tranexamic acid 5% in Syringe
Local Measures: Irrigation of wound with
            Tranexamic acid
Local Measures: Suturing the wound
Local Measures: Pressure with oral packs
Management of Intermediate Hemorrhage in
                   Normal patients

       The management of bleeding that occurs immediately
       after surgery (Reactionary bleeding) involves proper
       examination of the surgical wound to identify the site
       of bleeding (i.e ) from bone or soft tissue.

(i)    If bleeding is from bone then the hemostatic agents
       like bone wax or gelfoam is usually used.

(ii)   If bleeding is from soft tissues then, ligation /
       cauterization of blood vessels along with the use of
       hemostatic agents like surgicel and suturing of the
       wound is carried out.
Management of Secondary Hemorrhage in Normal
                   patients

   The management of this type of bleeding that occurs a
   few days after surgery involves the removal of any debris
   from the wound surface that promotes the infection of the
   wound.


   Identify the source of bleeding and treat as would be
   done in a patient with secondary bleeding.


   Surgical stents can be placed over extraction sockets for
   stabilization of clot and prevention of wound
   contamination.
Management of Hemorrhage in patients with
bleeding disorders / and those on anticoagulant
                    therapy


The usual protocol involved in the treatment of this
group of patients consists of pre-operative blood
investigations and preoperative correction of the
underlying deficiency (Replacement of Clotting factors /
platelets) if any in these patients.

Subsequently, after this appropriate local measures are
used to decrease the chances of post-operative bleeding.
LABORATORY EVALUATION


 PLATELET COUNT
 BLEEDING TIME (BT)
 PROTHROMBIN TIME (PT)
 PARTIAL THROMBOPLASTIN TIME (PTT)
 THROMBIN TIME (TT)
PLATELET COUNT

NORMAL             100,000 - 400,000 CELLS/MM3




< 100,000      Thrombocytopenia

50,000 - 100,000   Mild Thrombocytopenia

< 50,000           Severe Thrombocytopenia
BLEEDING TIME


  PROVIDES ASSESSMENT OF PLATELET
        COUNT AND FUNCTION



NORMAL VALUE
 2-8 MINUTES
PROTHROMBIN TIME

 Measures Effectiveness of the Extrinsic Pathway

NORMAL VALUE
 10-15 SECS
PARTIAL THROMBOPLASTIN TIME

   Measures Effectiveness of the Intrinsic
   Pathway




NORMAL VALUE
  25-40 SECS
THROMBIN TIME

Time for Thrombin To Convert
Fibrinogen          Fibrin
A Measure of Fibrinolytic Pathway


NORMAL VALUE
   9-13 SECS
Management of Hemorrhage in patients with
uncontrolled hypertension.

 This group of patients need appropriate medical
 consultation for initiation of medical treatment to
 decrease their Blood Pressure.

 Thus once their B.P is controlled, then the bleeding
 decreases and with local measures the hemorrhage is
 controlled.
THANK YOU

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Hemorrage in oral surgery

  • 1. Diagnosis and Management of Hemorrhage in Oral Surgery DR MOHAMMAD AKHEEL OMFS PG
  • 2. What is meant by Hemorrhage ? Prolonged or uncontrolled bleeding is often referred to as hemorrhage. The amount of blood lost as a result of hemorrhage can range from minimal to significant quantities.
  • 3. Hemorrhage in Surgery Hemorrhage can occur to a greater or lesser degree during all surgical procedures and it’s management depends upon whether the patient is hematologically normal or suffers from some disturbance in the normal clotting mechanism.
  • 5. Hemorrhage in Oral Surgery The overwhelming majority of patients who undergo oral surgical procedures are those who have normal haemostatic mechanism. Therefore, significant or major hemorrhages are not that common in oral surgery except in patients who have a bleeding / clotting disorder or those who are on anticoagulants.
  • 6. Hemorrhage in Oral Surgery However, uncontrolled and persistent bleeding can occur in some healthy patients after dental extraction. Therefore, it is still important to achieve proper hemostasis in all patients during oral surgical procedures, so as to prevent excessive post- operative blood loss.
  • 7. Normal Mechanism of Hemostasis Hemostasis is a complicated process. It involves a number of events
  • 8. Hemostasis - Normal Mechanism 1. VASCULAR PHASE 2. PLATELET PHASE 3. COAGULATION PHASE
  • 9. VASCULAR PHASE When a blood vessel is damaged, vasoconstriction results.
  • 10. PLATELET PHASE Platelets adhere to the damaged surface and form a temporary plug.
  • 11. COAGULATION PHASE Through two separate pathways, the Intrinsic and Extrinsic, the conversion of fibrinogen to fibrin is complete. Fibrin tightly binds the platelets to form a clot
  • 12. THE CLOTTING MECHANISM INTRINSIC EXTRINSIC Collagen Tissue Thromboplastin XII XI VII IX VIII X V FIBRINOGEN (I) PROTHROMBIN THROMBIN (II) (III) FIBRIN
  • 13. HEMOSTASIS DEPENDENT UPON: Vessel Wall Integrity Adequate Numbers of Platelets Proper Functioning Platelets Adequate Levels of Clotting Factors Proper Function of Fibrinolytic Pathway
  • 14. Hemorrhage in Oral Surgery Hemorrhage following Oral Surgical procedures can occur due to local or systemic causes. In healthy patients the postoperative bleeding is mainly due to local causes.
  • 15. Local causes of hemorrhage in oral surgery Local causes of hemorrhage originate in either soft tissue or bone.
  • 16. Local causes of hemorrhage in oral surgery – Soft tissue bleeding Soft tissue bleeding is either arterial, venous, or capillary in nature.
  • 17. Local causes - Soft tissue bleeding in oral surgery Arterial bleeding is bright red and spurting in nature. Arteries in the soft tissues at risk during oral surgical procedures are the lies posterior portion of hard palate) greater palatine artery and the buccal artery (lies lateral to the retromolar pad)
  • 18. Local causes - Soft tissue bleeding in oral surgery Venous blood is dark red in color and flows steadily and heavily especially if the vein is large . Capillary bleeding is bright red in color and is more of a minimal ooze.
  • 19. Local causes – Osseous (Bony) bleeding in oral surgery Troublesome bone bleeding originates either from nutrient canals in the alveolar region, central vessels, such as the inferior alveolar artery, or from central vascular lesions (Hemangioma or Vascular malformation)
  • 20. Systemic causes of hemorrhage in oral surgery Some patients with heriditary conditions such as hemophilia, Von Willebrand’s disease are susceptible for hemorrhage following oral surgical procedures. Patients with thrombocytopenia (decreased platelet count) , Leukemia e.t.c., are also at risk of prolonged bleeding after surgery. Patients with uncontrolled hypertension.
  • 21. Systemic causes of hemorrhage in oral surgery Patients with H/O prosthetic heart valve replacement, Stroke (Cerebrovascular accident) e.t.c., take oral anticoagulants like Aspirin or Warfarin to prevent the occurrence of a thromboembolic episode. These patients are also at risk of prolonged severe bleeding during and after an oral surgical procedure.
  • 22. Types of Hemorrhage - Primary Hemorrhage This occurs during the surgery, as a result of injury like cutting or laceration of the artery or bleeding from bone. This also occurs when surgery is done in an infected area with a lot of granulation tissue. It can also occur after a very short period of time immediately after surgery. This type of bleeding is really normal and can be controlled easily.
  • 23. Types of Hemorrhage - Intermediate / Reactionary Hemorrhage This type of bleeding occurs within a few hours after surgery. This type of bleeding occurs as a result of failure of coagulation to occur (as in patients with systemic bleeding problems or those on anticoagulants) Patients who have unknowingly disturbed / dislodged the clot are also prone for this type of bleeding.
  • 24. Types of Hemorrhage - Secondary Hemorrhage This occurs after 7 to 10 days after surgery. This is mainly due to partial division of blood vessel in combination with infection of the wound (Like patient’s who undergo radical neck dissection e.t.c.,). This type of bleeding is not very frequently encountered after oral surgery procedures.
  • 25. Management of Primary Hemorrhage in Normal patients The management of bleeding during surgery (Primary bleeding) can be achieved by the following means, (i) Securing / ligation of blood vessels with silk sutures. (ii) Use of pressure swab to achieve hemostasis. (iii) Use of electrocautery to achieve hemostasis. (iv) Use of hemostatic agents like bone wax, surgicel,e.t.c., (v) Hypotensive anaesthesia (G.A) and use of vasoconstrictors in L.A.
  • 26. Local Measures ( Synthetic Materials) There are several materials that are commercially available that are used locally for achieving adequate hemostasis.
  • 27. Local Measures: Surgicel (Oxidised Regenerated Cellulose)
  • 28. Local measures: Gelfoam with activated thrombin
  • 29. Local Measures: Avitene (Microfibrillar Collagen)
  • 30. Local Measures: Etik Collagen (Packed collagen)
  • 32. Local Measures: Tranexamic acid 5% in Syringe
  • 33. Local Measures: Irrigation of wound with Tranexamic acid
  • 35. Local Measures: Pressure with oral packs
  • 36. Management of Intermediate Hemorrhage in Normal patients The management of bleeding that occurs immediately after surgery (Reactionary bleeding) involves proper examination of the surgical wound to identify the site of bleeding (i.e ) from bone or soft tissue. (i) If bleeding is from bone then the hemostatic agents like bone wax or gelfoam is usually used. (ii) If bleeding is from soft tissues then, ligation / cauterization of blood vessels along with the use of hemostatic agents like surgicel and suturing of the wound is carried out.
  • 37. Management of Secondary Hemorrhage in Normal patients The management of this type of bleeding that occurs a few days after surgery involves the removal of any debris from the wound surface that promotes the infection of the wound. Identify the source of bleeding and treat as would be done in a patient with secondary bleeding. Surgical stents can be placed over extraction sockets for stabilization of clot and prevention of wound contamination.
  • 38. Management of Hemorrhage in patients with bleeding disorders / and those on anticoagulant therapy The usual protocol involved in the treatment of this group of patients consists of pre-operative blood investigations and preoperative correction of the underlying deficiency (Replacement of Clotting factors / platelets) if any in these patients. Subsequently, after this appropriate local measures are used to decrease the chances of post-operative bleeding.
  • 39. LABORATORY EVALUATION PLATELET COUNT BLEEDING TIME (BT) PROTHROMBIN TIME (PT) PARTIAL THROMBOPLASTIN TIME (PTT) THROMBIN TIME (TT)
  • 40. PLATELET COUNT NORMAL 100,000 - 400,000 CELLS/MM3 < 100,000 Thrombocytopenia 50,000 - 100,000 Mild Thrombocytopenia < 50,000 Severe Thrombocytopenia
  • 41. BLEEDING TIME PROVIDES ASSESSMENT OF PLATELET COUNT AND FUNCTION NORMAL VALUE 2-8 MINUTES
  • 42. PROTHROMBIN TIME Measures Effectiveness of the Extrinsic Pathway NORMAL VALUE 10-15 SECS
  • 43. PARTIAL THROMBOPLASTIN TIME Measures Effectiveness of the Intrinsic Pathway NORMAL VALUE 25-40 SECS
  • 44. THROMBIN TIME Time for Thrombin To Convert Fibrinogen Fibrin A Measure of Fibrinolytic Pathway NORMAL VALUE 9-13 SECS
  • 45. Management of Hemorrhage in patients with uncontrolled hypertension. This group of patients need appropriate medical consultation for initiation of medical treatment to decrease their Blood Pressure. Thus once their B.P is controlled, then the bleeding decreases and with local measures the hemorrhage is controlled.
  • 46.