Restoring Hormone Balance Booklet

Restoring
Balance works
Three simple steps to hormone therapy that

Bioidentical
hormone therapy
as individual
Restore® as you!

Our Mission
Since the first woman
suffering with symptoms
of hormone imbalance
walked through our
doors almost thirty years
ago, our mission has
been one thing and one
thing only — to provide
women, and men, with
options for healthy living
and healthy aging by
supporting hormone
balance — one unique
individual at a time.

Madison Pharmacy
Women’s Health America, Inc.
A S S O C I A T E S
Madison Pharmacy Associates, LLC • Restore, LLC
Madison BioDiagnostics, LLC • Cyclin Pharmaceuticals, Inc.

Table of Contents

The Women’s Health America Story 5

Is Hormone Therapy Right For You? 7
PMS Assessment
Menopause Assessment 8
Other Considerations 9
Personal Symptom Chart 10
WHA Self-Care Plan 12

Three Steps To Hormone Therapy That Works 15
Step 1. Baseline Testing 16

Step 2. Individualized Prescriptions 18
Bioidentical (Natural) and
Synthetic Hormones
What to Take 19
Patch, Pill or Cream? 24
When to Take It 26

Step 3. Follow-up Testing 27

Restore® Clinical Services Makes It Simple 29

Real Life Success Stories 31

Putting It All Together 37

Copyright © 2006 Women’s Health America, Inc. All rights reserved. This material is provided for
educational purposes only. It is not intended to treat, diagnose, cure, or prevent any disease and has
not been evaluated by the FDA. Always seek the advice of your healthcare provider with questions or
before undertaking any diet, exercise, or other health program.

4 Women’s Health America • 800.558.7046 • Fax 888.898.7412 • www.womenshealth.com

WHA
The WHA Story

Our story began more than 25 years ago when a young pharmacist, Marla Ahlgrimm,
was approached by a doctor who needed help with his patient — a 35-year-old woman
who suffered two weeks each month with severe mood swings, irritability, and depression.
Through research, Marla found that in Europe they had a name for the woman’s condition
— premenstrual syndrome. She also discovered that treatment options prescribed there
weren’t available in the United States.

Marla worked with the woman’s doctor to develop a special prescription that would modify
the woman’s hormonal fluctuations. Through Marla’s work, the woman became the first
patient diagnosed with severe PMS (now known as premenstrual dysphoric disorder, or
PMDD) in the United States, and the first to use natural progesterone. “The cloud lifted,”
was the exact phrase the woman used.

Doctors learned of Marla’s success and soon brought new patients to her to have
individualized prescriptions filled. In 1982, in response to the demand for customized
prescription services, Marla co-founded Madison Pharmacy Associates, the first
compounding pharmacy in America to specialize in women’s hormonal health.

Over the years, many of Marla’s patients began
coming to her for help with other concerns, How to
including menopause. She and her staff Use This
continued their research and developed even Booklet
more innovative, individualized hormone This booklet is designed to
therapies, and Women’s Health America, Inc., provide the information you need
was born. A few years later, Restore® Clinical to make starting a program of
Services was developed, offering comprehensive low-dose, bioidentical hormone
hormone therapy that included hormone testing, therapy easy and worry free.
individualized prescription care, and free follow-
We invite you to share it with
up testing to monitor outcomes.
your healthcare provider. If you
Today, the nurses, pharmacists and staff of have questions or concerns,
Women’s Health America have used Marla’s please call us for additional
unique approach to work with more than 10,000 information.
healthcare providers, offering individualized We can help!
hormone therapy to more than 300,000 women
— restoring balance, one woman at a time.

Women’s Health America • 800.558.7046 • Fax 888.898.7412 • www.womenshealth.com 5

You
Is Hormone Therapy
right For You?

You probably picked up this booklet because something’s not right — you just haven’t felt
like yourself lately. Maybe it’s PMS. Perhaps you’re approaching menopause and your hormone
levels are starting to change. You’d like to find out more about why you feel the way you do
and how to feel like yourself again.

You’ve come to the right place. Let’s start with a couple of simple assessments to see if hormone
imbalance might be the source of your discomfort.

PMS ASSESSMENT
If you are still menstruating and your symptoms appear regularly during the two weeks prior
to your monthly period, you may be suffering with premenstrual syndrome. Evaluate your
symptoms with our PMS Assessment.

Never Sometimes Often
Do you ... Score – 0 Score – 5 Score – 10
Find yourself crying for no reason?

Have dramatic mood swings?
Crave sweets, carbohydrates or chocolate?
Fly off the handle, feel irritable, anxious or hostile?
Have uncomfortably swollen, tender breasts?
Have weight gain, especially around the middle?
Have headaches, migraines and/or low back pain?
TOTAL

If your total score is 5 to 20, we recommend the Women’s Health America
Self-Care Plan on page 12 as the place to start for managing your symptoms. If symptoms
continue, you may also consider measuring your hormone levels. (See page 16.)

If self-care is not enough, or you scored more than 20, we recommend talking
with your healthcare provider about your symptoms and measuring your hormone levels with
a simple saliva hormone test. (See page 16.) If your hormone levels are outside of the normal
therapeutic range, hormone therapy may be an appropriate treatment.


Menopause Assessment

If you have reached menopause, either naturally or surgically, and you no longer
have periods, our Menopause Assessment will help you evaluate your symptoms.

If you are still having periods, but they have become irregular, or if
you think you are starting to experience symptoms of menopause, we
recommend you take the PMS Assessment and the Menopause Assessment, combine your
score, and review our recommendations.

Never Sometimes Often
Do you ... Score – 0 Score – 5 Score – 10
Have less energy, strength and endurance than you
used to have?
See more wrinkles every time you look in the mirror?
Find it easier to gain weight and harder to gain
muscle — especially in your midsection?
Have difficulty getting a good night’s sleep without
waking up repeatedly?
Have hot flashes or night sweats?
Just not care about sex the way you used to?
Find yourself starting to do something and not
being able to remember what it was?
TOTAL

If your total score is 5 to 20, we recommend the Women’s Health America Self-
Care Plan on page 12 as the place to start for managing your symptoms. If symptoms
continue, you may also consider measuring your hormone levels. (See page 16.)

If self-care is not enough, or you scored more than 20, we recommend talking
with your healthcare provider about your symptoms and measuring your hormone levels
with a simple saliva hormone test. (See page 16.) If your hormone levels are outside of the
normal therapeutic range, hormone therapy may be an appropriate treatment.


Other Considerations

The Benefits of Hormone Therapy Go Beyond
Symptom Management
Whatever you scored in your symptom assessment, remember that hormone therapy
is not just about keeping symptoms at bay. Far beyond mere symptom alleviation,
supplemental hormones play a key role in long-term health and wellness. They can
keep you looking and feeling younger. Hormones also assist in prevention of diseases
such as osteoporosis, cardiovascular disease, Alzheimer’s — and even certain types
of cancer. If you have a family history of any of these diseases, if you had an early
menopause, or if you have had your ovaries removed in a hysterectomy, bioidentical
hormone therapy may offer distinct long-term health benefits for you.

Not All Hormone Therapy Is Created Equal
Your hormone profile is as unique as your fingerprints or your DNA. And yet,
when it comes to hormone therapy, women are often treated as if we are all exactly
alike. It’s no wonder that an estimated 60 to 80 percent of women who begin
conventional hormone therapy stop taking their medication.

Standard-brand one size fits all prescriptions just don’t work for most women. For
hormone therapy to be right for you, your healthcare provider must consider your
specific needs, background, and lifestyle. You are a unique individual who deserves
careful, individualized treatment at the lowest effective dose.

Individualized Hormone Therapy
You can expect a better outcome from individualized hormone therapy than
from a one size fits all treatment where the same dose of the same synthetic
hormones is prescribed for most patients. From conventional to customized
medication, your bioidentical hormone therapy can be individualized by
utilizing hormones, dosages and delivery systems that meet your unique needs.

Lowest Effective Dose
Unlike one size fits all dosing, the lowest effective dose of a hormone is the
precise amount needed by an individual woman to relieve moderate to severe
symptoms and maintain optimal health without undesirable side-effects.


Personal symptom chart

When considering whether or not to begin
hormone therapy, a Personal Symptom Chart can be a
useful tool for you and your healthcare provider. Charting
symptoms on a daily basis will help show the pattern and
severity of your symptoms and their relationship to your
menstrual cycle or menopause.

The chart is also a useful tool for recording and evaluating
changes in your symptoms after beginning a program of
hormone therapy. For greatest accuracy, we recommend
you set aside a specific time to complete your chart
each day. Rate the level at which you experience each
symptom, using the scale of:

1 – Mild 2 – Moderate 3 – Severe

If you do not experience the symptom at all, leave the
box blank. After you’ve carefully charted your symptoms
for four or more weeks, discuss your findings with your
healthcare provider. Together, you’ll be able to see if there
is a pattern and discuss treatment options.

And remember — if you have questions,
we are always happy to help.
Call us at 800.558.7046
Monday – Friday 8am – 5:30pm CST

Restore®
Restore® is an exclusive program of Women’s Health America, Inc.
Madison Pharmacy Associates, LLC • Restore, LLC • Madison BioDiagnostics, LLC • Cyclin Pharmaceuticals, Inc.
1289 Deming Way • PO Box 259690 • Madison, WI 53725-9690 • 800.558.7046 • Fax 888.898.7412

Patient Name________________________________
Personal Symptom Chart
1-Mild 2-Moderate 3-Severe Date ________________________ Year __________

DAY OF CYCLE
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31
Food cravings – carbs/salty/sweet
Headaches or migraine
Breasts tender/sore/swollen
Rapid changes in mood
Low back and/or joint pain
Warm/flushed skin
Bloating/water retention
Fatigue/tired
Anxiety
Weight gain
Irritability/anger
Muscle weakness
Depression
Nervousness
Lack of energy/endurance
Acne/oily skin

SYMPTOMS
Rapid/irregular heartbeat
Forgetfulness
Hot flashes/night sweats
Vaginal dryness/pain/itching
Trouble controlling urine/leaking
Lack of sex drive/libido
Difficulty falling/staying asleep
Foggy thinking
Weight loss
Hand tremors
Decreased focus/attention

Women’s Health America • 800.558.7046 • Fax 888.898.7412 • www.womenshealth.com
Heavy or irregular periods
TALLY:

Women’s Health America
self-care plan
Many women find a few simple self-care measures go a long way in helping to
manage hormonal symptoms. That’s why — whether you choose prescription hormone
therapy or not — we recommend our self-care plan as the foundation of any symptom
management program.

STEP ONE: Your Healthy Diet
Instead of “three squares,” try eating three small meals and three
snacks daily. Frequent small meals keep your blood sugar stable and
avoid energy highs and lows. As you plan your meals and snacks,
include a mix of these healthy foods:
• Lean sources of protein — most women do not eat enough!
• Legumes (lentils and beans)
• Foods with soy protein (soy nuts, soy milk, or tofu)
• Raw and leafy vegetables and fresh fruit
• Low-fat milk, cheese, and yogurt
• Whole grain bread, cereal, and pasta
• Fish with Omega-3 fatty acids (tuna, mackerel, herring, sardines, salmon, shellfish)

Foods to avoid include salty lunch meat, sausage, bacon, high-fat cheeses such as brie, white
bread, cake, cookies, jam, honey, molasses, high-salt snacks like potato chips, caffeinated
drinks, coffee, tea, soda, and alcohol.

STEP TWO: Get Physical!
Moderate exercise is great for overall fitness and helps reduce stress.
Exercise raises HDL (“good cholesterol”) and reduces triglycerides (fats)
in the blood. It builds strong bones, increases heart and lung capacity,
and reduces fluid retention. It also causes the release of endorphins,
nature’s mood elevators, and increases oxygen and blood flow to muscles,
reducing tension. Research shows even a moderate amount of exercise
can help. In one study as little as 1 hour and 10 minutes of aerobics, 50
minutes of running, or 1 hour and 20 minutes of swimming a week
relieved symptoms.

A brisk 20 to 30 minute walk three times a week is a favorite exercise routine among
many women who contact Women’s Health America. And, because walking is a weight-
bearing form of exercise, it has the added benefit of building strong bones. Other forms of


weight-bearing exercise include dancing, tennis, certain yoga poses, running, and weight
training. The quantity and type of exercise are less important than exercising regularly.
We recommend about 20 minutes of exercise three or four times a week.

STEP THREE: The Right Nutritional Supplements for You
Our ProCycle® vitamin/mineral supplements were developed to support a woman’s
healthy hormone balance.

ProCycle® PMS was specially developed for women with PMS. This therapeutic
nutritional supplement contains a balanced combination of B vitamins, magnesium,
and calcium. ProCycle PMS contains a beneficial 2-to-1 ratio of magnesium to
calcium, shown to help regulate muscle relaxation and blood
sugar, and to promote sound sleep. Magnesium may also help
reduce the risk of heart attack, stroke, and hypertension, and
help prevent migraines in pregnant women.

ProCycle® Gold is designed exclusively for women during
perimenopause, menopause and beyond. It contains a precise
ratio of vitamin E, B vitamins, magnesium, calcium, zinc, and
boron. The calcium citrate in ProCycle Gold is easily absorbed.
ProCycle Gold is ideal for women using hormone therapy, as well as those who can’t take
estrogen or prefer to manage their menopausal symptoms by combining diet and exercise.

For more information about either ProCycle® vitamin or to order, call 800.588.7046 or
visit www.womenshealth.com.

STEP FOUR: Stress Management
The hectic pace of women’s lives can make it difficult to find time to relax. That makes
it even more important to set a regular time to slow down. For most women, relaxation
isn’t just one thing — it’s a balance of social, physical, creative, and spiritual activities. But
remember, if you experience ongoing physical symptoms or illness, don’t assume they’re
“just stress.” Talk to your healthcare provider.

STEP FIVE: Educate Yourself
Self-care also includes taking time to learn about your body and
options for healthy living. We recommend that every woman
read The HRT Solution by Marla Ahlgrimm, R.Ph. and John Kells.
Self Help for Premenstrual Syndrome by Michelle Harrison M.D. and
Marla Ahlgrimm, R.Ph., is another helpful reference for those with
PMS. For these books and the latest women’s health information,
simply visit our online bookstore at www.womenshealth.com.


Steps
Three Steps to Hormone
Therapy That Works

You’ve identified your symptoms and discussed them with your doctor. Your
self-care plan is in place as the foundation of your symptom management. You’ve
done some research and decided you would like to try hormone therapy — but
before you take any pills, apply patches, or rub in creams, you need the answers to
some questions. What should you take? How much should you take? When should
you take it?

Answering these questions involves three simple steps:
Three
Simple Steps
1. BASELINE TESTING
Measuring your hormone levels before starting 1. Baseline Testing
hormone therapy is essential for determining your 2. Individualized prescriptions
unique hormone profile. We also recommend a baseline 3. Follow-up testing
measurement of your rate of bone loss for use in
developing a self-care or prescription plan for preventing
osteoporosis.

2. INDIVIDUALIzED HORMONE PRESCRIPTIONS
When individualizing your prescription, there are many options to choose from.
Should you choose bioidentical or synthetic hormones? Which dosage form is best
for you? Our staff of nurses and pharmacists is here to help you and your healthcare
provider understand your options and make those critical decisions.

3. FOLLOW-UP TESTING
Periodic saliva hormone and NTx urine rate of bone loss testing are the most
accurate and convenient ways to monitor how well your hormone therapy
prescription(s) are working. These tests show if your medications have brought
your hormone levels and rate of bone loss within the optimal range. If you are
experiencing symptoms of overdosing or underdosing, follow-up testing takes the
guesswork out of finding where adjustments need to be made.


Step 1:
Step 1: Baseline Testing

Would you take blood pressure medication without first knowing what your blood
pressure is? Then why begin hormone therapy without first measuring your hormone
levels. Before taking any hormone medication, it just makes sense to know what your
hormone levels are and if they are within the recommended therapeutic range.

Baseline hormone testing for women should include:
• Estradiol • DHEA
• Progesterone • Cortisol
• Testosterone

We recommend saliva hormone testing over serum (blood)
hormone testing for its precision and convenience.

Saliva hormone testing is precise
Saliva or When measuring hormone levels, you want to know
Serum Testing? how much of the hormone is “free” or available to
work for you. Your saliva contains only the “free”
Blood (serum) tests do not always
distinguish between free and bound form of your hormones, so it is an excellent way to
forms of hormones, so the results measure this. Blood tests, on the other hand,
of a blood test are less precise measure both the free and the inactive, or “bound”
than saliva testing. form of hormones. This measurement is less useful
since bound hormones are no longer available to
work for you.

Saliva hormone testing is convenient
The convenience of saliva testing is another plus.
Our test kit allows you to collect saliva samples in the privacy of your home and use
the mailer provided to send them back to our lab for evaluation. This is easier, more
convenient and more cost-effective than making an appointment with a local lab for
serum testing.

Results from your saliva test are sent to your healthcare provider along with our
suggestions for your individualized hormone therapy prescription.


NTx urine testing measures rate of bone loss
Osteoporosis is one of the greatest health concerns for women. Though
many believe osteoporosis is a normal part of the aging process, this is not
true. Lifestyle and diet are putting younger generations at a higher risk than
the generations that went before them. That is why we also recommend an
NTx urine test to measure rate of bone loss.

The NTx urine bone loss test is a simple and affordable test where a urine
sample can be collected at home and mailed to our lab for analysis. Results
can be used to:

• Help assess who will receive the greatest long-term bone health benefit
from hormone therapy.
• Determine the probability of bone mass decreasing in a postmenopausal
woman if she does not initiate hormone therapy.
• Monitor response once hormone therapy is begun.

In as little as three months, NTx measurements can show the effect of your
bone loss prevention self-care plan and/or prescription therapy. This is a
distinct advantage over the one to two years required to see a change in bone
densitometry (DEXA) measurements. You can understand why NTx bone
marker technology plays such an essential role in preventing and managing
the bone loss that leads to osteoporosis. DEXA testing simply is not enough.

Bone Remodeling
Strong, healthy bone is continually maintained through the two phases of bone
remodeling: resorption (removal) and formation. Bone-resorbing cells called osteoclasts
remove old bone by releasing acids and enzymes to remove minerals and collagen. Cross-
linked N-telopeptides (NTx) are released into the bloodstream during osteoclastic activity.

Once the osteoclasts have done their job, protein-secreting cells called osteoblasts are
recruited to the newly resorbed areas on the bone where they deposit new collagen to form
new bone.

Approximately 20% of bone tissue is replaced annually by this process. When resorption
and formation are in balance, there is no net change in bone mass. Disease states,
such as osteoporosis, occur when resorption is more active than formation.


Step 2:
Step 2: Individualized
Prescriptions
The consulting pharmacists at Madison Pharmacy Associates work with many women and
their healthcare providers to individualize hormone therapy regimens, and are available to advise
you and your healthcare provider. Before getting started, it is important to understand why we
use only natural, bioidentical hormones in our prescription formulations.

Bioidentical (Natural) and Synthetic Hormones

Bioidentical and synthetic hormones are very different — the difference is in the
molecular structure. A bioidentical hormone has a molecular structure that is identical
to the hormones naturally produced by the body. That’s why bioidentical hormones
are also referred to as “natural.”

A “synthetic” hormone has a molecular structure similar to but not exactly the same as
the hormones produced by your body. This difference can mean synthetic hormones
interact differently in your body, producing substantially different effects.

For example, let’s look at the difference between the synthetic progestins and
bioidentical progesterone. The synthetic progestins, such as commonly prescribed
Provera®, are similar to the progesterone your body produces, but the subtle molecular
differences can significantly influence the hormone’s action. Synthetic progestins
can cause side-effects of irritability, nausea, depression, and water retention in some
women. Bioidentical progesterone is identical to the hormones made in the body,
and many women find it easier to tolerate.

PROGESTERONE
CH3 You can see that the
C O
CH3
synthetic hormone
O
C O medroxyprogesterone
O C CH3
acetate, commonly known
as Provera® (bottom),
has a different molecular
CH3 structure than natural
MEDROxYPROGESTERONE progesterone (top).
ACETATE (PROVERA)


What To Take: Estrogen, Progesterone, Testosterone

There is no set combination or dosage of hormones that works for every woman.
Hormone therapy typically includes estrogen, progesterone, and/or testosterone.
However, it is also important to measure your levels of DHEA and cortisol as these
hormones may influence levels of the other three.

Which hormones you need and the amount you need depend upon your individual
hormone levels and symptoms.

• PREMENSTRUAL SYNDROME: Symptoms of PMS such as mood swings,
cravings for sweets and chocolate, anxiety, irritability, and crying for no
reason may be associated with low levels of progesterone and relatively
elevated levels of estrogen.
• PERIMENOPAUSE: Declining levels of estrogen and progesterone,
and, in some cases testosterone, may be associated with perimenopause
symptoms such as hot flashes and sleep disturbances.
• MENOPAUSE AND BEYOND: Lower levels of estrogen, progesterone,
and testosterone which are typical after menopause, may be associated with
hot flashes, sleep disturbance, bone loss, and loss of libido.

Let’s look more closely at these hormones and what they do in our bodies.

While we tend
Estrogens: They’re not all alike
to think of estrogen’s
“Estrogen” is often used as a general term,
relationship to our
but it is actually a category of hormones. Of
reproductive function first, this
the many types of estrogen our bodies make, hormone actually nourishes and
three are produced in major amounts. protects our bodies in hundreds
of ways, from our hearts, to our
Many women call Women’s Health
bones, to our skin and hair. In the
America and the consulting pharmacists uterus, estrogen causes the lining
at Madison Pharmacy Associates to ask (endometrium) to thicken
if there is a “natural estrogen” they can and build up each month
take. They are often surprised to learn until it is sloughed as
that commercially manufactured and a menstrual
frequently prescribed forms of estrogen are period.
bioidentical (or natural) estrogens.


Choosing among estradiol, estrone and estriol is a
Estrogen decision best made based on the specific symptoms
Bioidentical estrogens,
that need to be managed. Specially compounded
derived from soy, include
estrogens like Biest or Triest combine two or three
estrone, estradiol, and estriol.
Estrogen protects against:
of the natural estrogens: estradiol, estrone,
• Osteoporosis and estriol.
• Alzheimer’s disease
• Colon cancer
Estradiol
• Urinary incontinence Estradiol is the most potent form of estrogen,
• Tooth loss/decay and the one produced in the largest amounts
Estrogen enhances: by a woman’s ovaries before menopause.
• Mental sharpness/memory Estradiol levels decline after menopause. The
• Brain molecules like brand names Estrace®, Estraderm®, Vivelle®,
serotonin and endorphins Alora®, FemPatch™, Estring®, and Climara®
• Sleep
contain bioidentical estradiol.
• Mood
• Digestion
Estrone
• Sex drive Estrone is the predominant estrogen in a woman’s
• Skin tone
body after menopause. When ovarian function
declines, the fat cells in a woman’s body take over the
role of synthesizing estrone.

Estriol
Estriol is known as the “weak” or “forgotten” estrogen. Primarily produced in
large amounts by the placenta during pregnancy, estriol is also converted in
small amounts by the liver. The fact that estriol is “weak” has pluses and
minuses. Estriol has been used vaginally to manage vaginal dryness, urinary
infections, and stress incontinence. Estriol does not provide as much heart
and bone protection as other more potent estrogens like estradiol and
estrone. However, low doses of estriol typically have little or no effect for
most women on breast or uterine tissue, so estriol avoids the risk of breast
or uterine cell abnormalities associated with estradiol and estrone. Estriol can
be taken alone, without progesterone, because it has little to no effect on the
uterine lining. A woman who suffers from vaginal dryness and/or incontinence
with no family history of heart disease or osteoporosis and with cholesterol and
bone density levels within normal ranges, may be a good candidate for estriol.
Estriol is not commercially available in the U.S. and must be compounded
by a pharmacist.


Progesterone
The balance of progesterone and estrogen in a woman’s body is very important.
At different times in her life, an imbalance in these hormones can result in
symptoms of PMS, perimenopause, or menopause. Symptoms of progesterone
imbalance include mood swings, anxiety, cravings for sweets, depression,
weight gain, bloating, and breast tenderness.

When taken alone as a medication, estrogen can cause the cells in the uterine
lining to become crowded or malformed. Progesterone, on the other hand,
controls that effect, protecting you from endometrial abnormalities. You can
choose between synthetic forms of progesterone (progestins) and bioidentical
progesterone (progesterone USP), which must
be compounded by a pharmacist. At
Madison Pharmacy Associates, we only Progesterone
use bioidentical progesterone in The balance of progesterone
our formulations. and estrogen in a woman’s body
is very important. Progesterone
Arriving at the right bioidentical USP (Natural Progesterone
estradiol/progesterone combination Cream, Prometrium®, Crinone®) is
for you can take some time and a bioidentical progesterone derived
adjustment. For many women, from wild yam or soy.
Progesterone:
0.5 mg of estradiol and 100 mg of
• Decreases risk of endometrial cancer
progesterone USP is a good starting
• Stabilizes blood sugar, thyroid
dosage. The dosage of progesterone,
function, and mineral balance
however, may vary depending on the
• Is necessary for fertility and
route of administration, and whether maintaining a pregnancy
you are on a continuous or cyclical • Increases energy and sex drive
regimen. If the initial dose gives you • May help protect against breast
uncomfortable side-effects or doesn’t cancer, fibrocystic breasts,
alleviate your symptoms, your healthcare and osteoporosis
provider can adjust the dose or try a • Regulates fluid balance
different route of administration such as a • Has a calming effect
patch, cream or tablet, depending on your • Enhances mood
individual situation.

Testosterone
While traditionally thought of as the “male” hormone, testosterone plays a
dramatic role in many aspects of a woman’s physiology and quality of life,


including libido, sexual satisfaction,
bone density, sense of well-being, TESTOSTERONE
vasomotor symptoms, and body An androgen, produced in men
and in substantially smaller amounts
composition. Testosterone is particularly
in women, this hormone declines in
important because it activates the sexual
both men and women as they age.
circuits in the brain.
Testosterone:
At menopause when our ovaries no longer • Builds and promotes muscle tone
release eggs, they also stop producing the • Increases energy
• Decreases fatigue
potent forms of estrogen (estradiol and
• Increases sex drive
estrone) and progesterone, and they slightly
• Enhances well-being
decrease production of testosterone, which
• Strengthens bone
changes the ratio of testosterone to estrogen
and progesterone.

Today it is not unusual to include testosterone in a woman’s hormone therapy
regimen. Transdermal patches, sublingual tablets, topical gels, and oral capsules
can be prescribed and individually compounded for each patient using
bioidentical testosterone.

DHEA
Another critical hormone manufactured in the adrenal glands is dehydroepiandros-
terone, commonly known as DHEA. DHEA has received a great deal of media
attention and is often referred to as the fountain of youth hormone.

Levels of DHEA peak at about 20-25 years
DHEA
of age then begin to decline. DHEA protects
Called the “fountain of youth”
hormone, DHEA helps protect against the effects of stress. The decline of
against ailments associated with DHEA levels that comes with age correlates
aging such as cancer, diabetes and with a general decline in immunity, memory,
heart disease. libido, energy, and lowered resistance to age-
DHEA: related diseases.
• Enhances brain function and memory
• Supports the immune system Unfortunately, DHEA’s fountain of youth
• Helps prevent blood clots reputation has led to a dramatic increase in its
over-the-counter usage. We say unfortunately,
because there are some significant potential side-
effects from taking too much of this hormone.


Remember, hormones are powerful substances the body produces to carry out critical
functions, and the level of one hormone can affect the level of another. When other
hormones are balanced, DHEA levels typically increase without supplementation.
On the other hand, too much DHEA can “cascade” or turn into other hormones in
the body, creating imbalance and the side-effects associated with it.

DHEA is also a mild blood thinner and stimulant, which can lead to over-stimula-
tion of the thyroid. People who take aspirin, blood thinners, stimulants, or a thyroid
prescription may need to have dosages altered if they are also taking DHEA.

Though DHEA is available without a prescription, measuring your hormone levels
before supplementing this hormone is as important as with any other hormone.

Cortisol
The most important and potent hormone produced in the adrenal glands is cortisol,
known as the stress hormone. Cortisol helps in responding to and coping with stress,
injury, and infection. It also affects the activity of other hormones such as insulin,
thyroid, and DHEA.

Cortisol is involved in balancing blood CORTISOL
sugar, protein synthesis, proper immune Often referred to as the
“stress” hormone.
function, and REM sleep — the deep sleep
Cortisol helps:
where the body is relaxed, but the brain is
• Cope with stress and injury
active and dreaming. It also affects rate of
• Control weight gain
bone breakdown. • Balance blood sugar
• Maintain immune function
Chronic stress may decrease your cortisol
• Aid protein synthesis
level while acute stress may elevate it. As
• Improve REM sleep
with other hormones, too little or too much
cortisol can be damaging. The symptoms of
too little cortisol include fatigue, sugar craving, allergies, molecular sensitivity, stress,
cold body temperature, and heart palpitations. Too much cortisol can result in sleep
disturbances, depression, bone loss, weight gain in the midsection, thin skin, and
loss of muscle mass.


Patch, Pill, or Cream?
There are many forms of bioidentical hormone therapy to choose from, ranging
from conventional forms like the estradiol patch, to customized forms like the
Even-Release Oral Tablet or the aplía™ Metered Transmucosal Applicator —
available exclusively from Madison Pharmacy Associates.

There are several factors you and your healthcare provider will want to consider
when choosing the dosage form that is best for you. These include:

• Symptom Management. Identifying
the symptoms you want to manage will
help determine the appropriate dosage
form. For example, the level of heart
and bone protection differs with various
hormone dosage forms. Your individual
profile and family history may also come
into play.
• Convenience. Some women choose the
form of hormone therapy that is easiest for
them to remember to take.
• Cost. For some women, cost factors into
their decision.

Points to keep in mind
When deciding between oral, vaginal cream, transdermal patch, or
transdermal cream estrogen, here are a few points to keep in mind:

• The skin patch may be a good choice for you if your triglyceride levels are abnormally high.
Transdermal estrogen does not raise triglyceride levels. Oral estrogen appears to increase triglyceride
levels somewhat because it passes through the liver.
• The aplía™ Metered Transmucosal Applicator, may be a convenient tool for you if you are using
multi-hormone therapy creams. Each metered dose is quickly absorbed transmucosally, without
all the mess of most creams.
• The adhesive on the estrogen skin patch sometimes causes skin irritation and the
patch is more expensive than oral estrogen.
• Estrogen in cream form is very effective in treating urinary and vaginal problems.
• Vaginal estrogen creams may not protect against heart disease
or bone loss.


Available Exclusively from Madison Pharmacy Associates
Several of our dosage forms have been developed by and are available exclusively
from Madison Pharmacy Associates.
IG
OR IN

™
Metered Transmucosal Applicator
TM
MPA

AL
S

Our latest advancement in precise, controlled hormone replacement
therapy dosing - aplía™! Convenient and discreet, the aplía applicator
is designed to administer a metered dose of multi-hormone cream
directly to the vaginal opening or labial area. An FDA approved
devise, aplía offers a convenient alternative to messy creams.
IG
OR IN
s Customized Transmucosal
Even-Release Oral Tablet
MPA

AL

Applicator
S

This breakthrough progesterone delivery system introduced in 1986, combines slow,
Even-Release of medication with the convenience of dosing once or twice daily.
IG
OR IN

Rapid Act Sublingual Tablet
MPA

AL
S

Our innovative sublingual (under tongue) delivery system is convenient, pleasantly
orange-flavored, and dissolves under the tongue in less than one minute. Sublingual
tablets can be compounded using hormones such as progesterone, testosterone, DHEA,
estradiol, estriol, Triest, Biest, and pregnenolone, either singly or in combination.
IG
OR IN

Customized Transdermal Patch
MPA

AL
S

This is not a standard-dose, one size fits all patch,
but one that is created and dosed just for you. The
innovative patented matrix of our transdermal
patch acts as a reservoir for continuous delivery of
individual or combined hormone therapy.
IG
OR IN
MPA

Percutaneous Gel
AL
S

s Customized Transdermal Patch
Our patented gel delivery system allows the natural matrix of the skin to deliver
continuous, consistent absorption of individual hormones or hormone combinations
with the convenience of once a day dosing.
IG
OR IN

Oral and Chewable Tablets
MPA

AL
S

Oral tablet dosages can be compounded using single or a combination of hormones
including progesterone, estradiol, estriol, DHEA, pregnenolone, testosterone, Biest, and Triest.
Chewable tablets can be formulated for those who have difficulty swallowing medication.
IG
OR IN

Micronized “In Oil” Oral Capsule
MPA

AL
S

These oral capsules can be compounded with a single or combination of hormones including
progesterone, estradiol, estriol, Triest, Biest, DHEA, liothyronine, thyroid, and pregnenolone.


IG
OR IN

MPA

AL
Creams and Ointments
S

Hormone creams and ointments offer complete strength and dosage flexibility. Studies
show that wild yam and hormone creams available over the counter vary widely in
content, effectiveness, potency, quality, and price. Prescribed hormone creams assure
you a quality therapeutic product, often at a lower price than those products available
without a prescription, and are subject to insurance reimbursement.
IG
OR IN

Anti-Aging Facial Serum
MPA

AL
S

Estriol, the mildest of all estrogens, has been shown to
reverse the signs of skin aging and wrinkling in perimenopausal
and menopausal women. With a prescription from your health-
care provider, Madison Pharmacy Associates can compound an
estriol facial cream just for you.
IG
OR IN

Suppositories and Vaginal Tablets
MPA

AL
S

A variety of hormones can be compounded in suppository
form for vaginal or rectal use. Using specialized vaginal tablet disintegrant systems,
we compound a variety of vaginal hormone tablets that require no special storage
conditions and need limited vaginal moisture to dissolve.

Conventional Estradiol Patch
Low-dose, commercially prepared, bioidentical estradiol patches such as Climara®
and Vivelle® are also available from our pharmacy.

When to take it
There are two regimens to choose from when individualizing your hormone
therapy: cyclical and continuous combined.

CYCLICAL is recommended for women still cycling because it mimics a menstrual
pattern. Using this regimen, you take progesterone on days 14-28 of a 28-day cycle;
estrogen (if needed) days 1-21; and testosterone (if needed) daily. When you finish
taking progesterone each month, you experience bleeding as your body “withdraws”
from the hormone progesterone, and the endometrial lining sloughs away.

CONTINUOUS COMBINED is recommended for women who are no longer
having menstrual cycles. Using this regimen, you take estrogen and progesterone
every day. This eliminates breakthrough bleeding though there may be some
initial spotting in the first one to three months. Women also experience fewer
side-effects with this regimen.
Consult with your healthcare provider to determine which regimen is best for you.

Step 3:
Step 3: Follow-up Testing

According to Dr. Wulf H. Utian, Executive Director of North American
Menopause Society:

1) No single hormone “recipe” exists that will fit every woman. The first regimen
you try may not work for you, but don’t give up. Your doctor should fine-
tune your hormone regimen to your individual needs, your risk factors, your
symptoms and your lifestyle, before and during therapy.

2) The therapy must be evaluated at least annually by both you and your
healthcare provider, sooner if you experience side-effects or problems.

Follow-up testing is the most scientific
and accurate way to take the guesswork
out of finding the right “hormone recipe”
for you and for evaluating your therapy.
A follow-up hormone test and NTx urine
test will show your healthcare provider
exactly how your body has responded to
the hormone medications you are taking.
Test results can than be used to help
s NTx Testing
determine any adjustments that may
be needed.

Follow up Testing
After three months of initial therapy, it’s time to measure your hormone
levels and NTx bone metabolism again to see how they have changed, and if
they are now within the desired therapeutic range. The results of these tests,
along with your symptom chart, will help you and your healthcare provider
decide if any change to your medication is advised.

An annual evaluation thereafter will help you and your healthcare provider
know if your hormone levels are within the desired therapeutic range or if
additional adjustments may be beneficial.


Restore
Restore® Clinical Services
Makes It Simple

Individualized, low-dose hormone therapy is the wave of the future, but it
is new for many healthcare providers. Fortunately Women’s Health America and
Madison Pharmacy Associates have successfully used this approach for more than
twenty years. Our Restore® Program was the first and remains the only comprehensive
hormone therapy program of its kind to provide testing, individualized prescriptions,
and on-going evaluation. Our Restore nurses and pharmacists work with you and
your healthcare provider to make the best therapeutic decisions for your unique needs.
The Restore® Program includes:
“The Restore®
1. Baseline testing. We provide analytical measurement program from
of saliva to determine your levels of estrogen, progester- Women’s Health America
one, testosterone, DHEA, and cortisol. NTx urine is provides customized dosing
used to measure rate of bone resorption. for individual patients,
2. Individualized bioidentical prescriptions. merging the patient clinical
We work with your healthcare provider to customize needs with supporting
your prescription at the lowest effective dose recom- laboratory data. It’s the future
mended for your symptoms and medical history. of hormone therapy.”
3. Follow-up saliva hormone and NTx urine - Claude Hughes, M.D.,Ph.D.,
testing. At three months, follow-up testing helps to Duke University
determine necessary lifestyle/medication adjustments Medical Ctr.
needed to maintain hormone levels in a therapeutic
range, avoiding the side-effects of overdosing and the
consequences of underdosing.
Restore® offers a revolutionary fourth step — FREE annual follow-up testing.
The Restore clinical team assists in evaluating and adjusting your ongoing plan of care
to assure optimal therapeutic outcomes at the lowest effective dose for as long as your
hormone prescriptions are filled through our pharmacy, Madison Pharmacy Associates.

Getting Started
Getting started in the Restore® program is easy. Simply have your healthcare
provider complete a Restore enrollment form and fax it to us at Women’s Health
America. We’ll take care of the rest — from mailing your sample collection kit to
faxing results to your healthcare provider.
Please call our Restore® Specialists at 800.558.7046 if you would like more
information for you or your healthcare provider.

Real Life
Real Life Success Stories

Thousands of women have used saliva hormone testing as part of an
individualized hormone therapy program. The following stories illustrate the success
of this revolutionary approach.

Jane Ann
Jane Ann is a 49 year-old financial planner who relied on
a self-care program that included a healthful diet, a regular
workout, and ProCycle® Gold vitamin-mineral supplement
to manage her occasional hot flashes. Gradually, in spite
of everything she was doing on her own, Jane Ann’s hot
flashes became a daily (and nightly) occurrence. A person
who prides herself on keeping details within her grasp, Jane
Ann also noticed a few gaps in memory that concerned
her. She would call a client on the phone and, right after saying hello, forget why
she called. Or, plucking a report from her shelf, she would search through it and
suddenly forget what she was looking for.

Jane Ann decided to discuss her concerns with her doctor during her routine
annual physical exam. She told him she had not had a period for quite a few
months. During their conversation, she admitted that, along with her other
symptoms, she was also feeling close to tears more frequently, often without any
reason she could identify. Jane Ann’s doctor listened intently and then explained
to her that her symptoms, combined with her age and the fact that her cycles
seemed to be waning, led him to believe she was entering menopause and her
estrogen level was low. He gave her a prescription for Premarin® and Provera®,
a commonly prescribed combination of conjugated estrogens and a synthetic
progestin.

A week later, Jane Ann was on the phone with her doctor, reporting that
her symptoms seemed worse. Her normally cheerful outlook was bleak, her
breasts were very tender, and she felt bloated. She didn’t understand what
was happening.
(continued)


Having just returned from a seminar on saliva hormone testing, Jane Ann’s
doctor suggested running a saliva hormone test to measure her free hormone
levels. After reviewing the results of the saliva measurement, he could see that
her estradiol level was now above the expected range of 3 to 5pg/ml for a woman
who is still having her menstrual cycle. Jane Ann’s estradiol level was 18.7 pg/ml.
Her doctor correctly surmised that her symptoms were being exacerbated by the
excess amount of estrogen she was getting from her prescription.

To find the right dose of hormone for Jane Ann,
her doctor consulted with a Madison Pharmacy
“... many Associates pharmacist knowledgeable in saliva
women find hormone test interpretation and individualized,
“bioidentical” bioidentical hormone dosage. Knowing that
many women find “bioidentical” hormones
hormones — which are molecularly identical to the
— which are hormones a woman’s body produces — easier to
molecularly tolerate, the pharmacist suggested changing Jane
Ann’s prescription from Premarin® and Provera®
identical to the to bioidentical estradiol and oral micronized
hormones a progesterone. He also suggested adjusting her
woman’s body dosages to 0.5mg of estradiol and 100 mg of
progesterone, to be taken twice a day.
produces —
easier to Within a day or two, Jane Ann felt like herself
again. A follow-up saliva test 30 days later
tolerate ...” showed that indeed, her estradiol level was 3.2
pg/ml and her progesterone level was 0.4 ng/ml.
Both were well within the ranges that occur in a
woman who is still menstruating. Jane Ann’s hot
flashes were under control, she wasn’t teary any
longer, and best of all, she felt like herself again.


Celeste
Celeste is a healthy and active woman. When she started to have
perimenopausal symptoms at 47, she decided to try self-help
measures to get herself through the change. She read books on
natural approaches to menopause, adjusted her diet, began an
exercise regimen, and took nutritional supplements and herbs.
Three months later, she still found herself crying at the drop of a
hat, craving foods like pasta, chocolate and potatoes, and having
increasingly hotter hot flashes. Both she and her husband grew
frustrated. One night, her husband even bolted upright in bed and said, “What is it
with you and the covers? One minute they’re on, the next minute they’re flying off!”

Celeste continued her search for answers to her perimenopausal woes. She found an
over-the-counter natural progesterone cream on the Internet. When Celeste received
her cream, she read the instructions. She assumed that even though her periods had
become irregular, she should take the dose recommended for a premenopausal woman
who is still menstruating. For several weeks, while Celeste was using the cream, she had
good results: improved mood, fewer food cravings, less frequent hot flashes, and more
restful sleep. But, within a short time, her symptoms seemed to be returning.

She wondered if she might be farther along in the
change than she had originally thought. “Maybe “On top of
I’m not using enough of the cream,” she wondered. everything else,
She decided to apply more. Almost immediately,
Celeste began feeling sleepy all the time. On top of
her sex drive was
everything else, her sex drive was dwindling, and dwindling, and
she was becoming increasingly worried. What if she was becoming
it wasn’t the change at all? What if something was
really wrong with her? She stopped using the cream
increasingly
and made an appointment with her doctor. worried.”
Celeste told her doctor what was happening and
he ordered a blood test to measure her hormone levels. The results showed that her
estrogen and progesterone levels were what you would expect in a woman who is still
menstruating. “Your hormones look fine,” her doctor told her. “Maybe you are just
having a hard time adjusting to your body changing.” Celeste was puzzled and frustrated.
She intuitively knew this wasn’t just in her head — something was going on with her
hormones. (continued)


She stopped using the progesterone cream and spent a few more late nights on
the Internet. There she found some interesting information from Women’s Health
America on saliva hormone testing. She was intrigued enough to call her doctor and
ask if saliva testing would be appropriate for her. Although he wasn’t familiar with
saliva hormone testing, he agreed to review the information Celeste had found. A
few days later he called back to say he was willing to order the saliva hormone test
and consider the results.

Celeste had two saliva hormone tests, 30 days apart. At first, her progesterone levels
were .03 ng/ml, well below the target range for a woman her age who was still
menstruating. After consulting with a Madison Pharmacy Associates pharmacist,
Celeste’s doctor offered her the option of continuing to use the over-the-counter
cream she had in a lesser amount, or he could give her a prescription cream. In
either case, it was important to monitor the dosage more closely than Celeste had
been able to do when she applied the over-the-counter cream in varying amounts.
Celeste chose to use the prescription cream. She began feeling better right away.

After another month of using her new prescription progesterone cream, Celeste was
feeling quite well. However, her follow-up saliva test showed that her progesterone
level was slightly above the expected range. This information indicated that
her dosage could be decreased. Her doctor lowered her dosage again, this time
recommending that she use only 10 mg of cream a day, in two doses of 5 mg each.
Celeste felt terrific using this amount, and 30 days later her saliva test showed her
progesterone level at .4 pg/ml — right within her target range.

Three very important things were accomplished in Celeste’s case:

• First, she and her doctor were able to obtain a precise picture of her free
hormone levels using saliva testing.
• Second, together with a pharmacist knowledgeable in individualized,
bioidentical hormone therapy, Celeste’s doctor was able to adjust her
dosage to exactly what she needed.
• Third, Celeste and her doctor have an ongoing means of monitoring
her progress with follow-up testing and dosage adjustment as needed. As
Celeste’s body continues to change, her hormonal level requirements may
change, too. When they do, she and her doctor can respond with more
information and less guesswork.


Frieda and Sam
Having too much of a hormone can cause
uncomfortable side-effects, but as Frieda
experienced, too little of a hormone can cause
discomforts as well. Frieda and her doctor used
saliva testing to determine which hormones she
needed to help with her declining sex drive.

A widow at 56-year-old, Frieda had recently married Sam. Even though they were happy
and very much in love, both Frieda and Sam felt like their relationship lacked the sexual
spark they had each known in the past. Frieda had seen headlines about testosterone’s
ability to re-ignite her desire. She asked her doctor if testosterone might help her and Sam
feel more interested in lovemaking again.

Frieda’s doctor wasn’t ready to take that step without more information. He talked with
Women’s Health America about measuring Frieda’s estradiol, progesterone, DHEA,
cortisol, and testosterone levels so he could have the most complete picture of her
hormonal profile. We suggested he also measure Sam’s levels of estradiol, DHT, DHEA,
and testosterone.

Frieda “With Frieda and
Frieda’s baseline saliva test showed low estrogen Sam’s hormones
and progesterone, but the amount of DHEA,
back in balance,
cortisol, and testosterone her body was producing
were fine. In Frieda’s situation, balancing her the newlyweds
progesterone and estrogen levels was all that were worry-free,
was needed to restore her libido. Supplemental
testosterone might have produced unwanted side-
and began looking
effects. Thanks to saliva testing, Frieda didn’t have forward to a long
to worry about side-effects because she was taking and fulfilling
exactly what she needed.
relationship.”
Sam
Sam’s baseline saliva test showed that his testosterone level was below the normal
therapeutic range. To bring his hormones back into balance, his doctor prescribed a 20
mg/gm testosterone gel to be applied once daily. Like Frieda, Sam also started to feel like
himself again. With Frieda and Sam’s hormones back in balance, the newlyweds were
worry-free, and began looking forward to a long and fulfilling relationship.


A Note
Putting It All Together

A note from Marla Ahlgrimm, R.Ph.
Founder and CEO, Women’s Health America, Inc.

Hormones control many aspects of our lives. Hormone imbalance can be the
source of PMS and the many unwelcome symptoms of perimenopause, menopause,
and for men, andropause. The natural decline in hormone levels as we age can also
be the source of health problems like osteoporosis and cardiovascular disease.

Self-care can go a long way toward managing symptoms of hormone imbalance and
decline. When self-care is not enough, saliva testing is a simple means for assessing
many of the variables involved in choosing a hormone therapy program. These
variables include the individuality of your own hormone profile, the unique way
you absorb and utilize hormones, and the way your needs change over time.

With its emphasis on balance and synergy, the goal of our Restore® program for
individualized hormone therapy is to put an end to overdosing and underdosing of
critical hormones. This comprehensive approach using bioidentical hormones, saliva
testing, and free follow-up testing is designed to take the confusion out of hormone
replacement while meeting each woman’s individual needs.

Remember, there are many variables to consider in hormone therapy. Everything
from how old you are to the level of stress in your life affects what is going on with
you hormonally. Who you are and how your body works is a key factor in the way
your hormone restoration program will work for you. Our revolutionary,
individualized approach to hormone therapy is a giant leap forward in healthcare
and anti-aging.

I hope you found the information in this booklet valuable. If you still have
questions about whether hormone therapy is right for you, please call us at
800.558.7046 or visit www.womenshealth.com. We can help!

In good health,


WHA
Women’s Health America

• Madison Pharmacy Associates
From conventional to customized, our pharmacy can fill all your bioidentical
hormone therapy prescriptions.

• Madison BioDiagnostics
Our full line of laboratory services includes saliva hormone testing, NTx urine
bone loss analysis, and more.

• Restore® — Exclusively from Woman’s Health America, Inc.
This innovative program for comprehensive hormone therapy combines
low-dose, bioidentical hormone therapy with baseline testing and free follow-up
testing to monitor outcomes.

• Free Follow-up Testing
FREE annual hormone testing and NTx bone loss analysis are provided for anyone
who’s hormone prescription(s) are filled through Madison Pharmacy Associates.

• Health Care Provider Referral
Use our preferred provider listing to locate hormone therapy healthcare
professionals in your area.

• www.womenshealth.com
You’ll find extensive information about bioidentical hormone therapy, PMS,
menopause, perimenopause, andropause, and more on our website.

Questions about which services are right for you?
Our staff of professionals are available to answer your questions
Monday through Friday 8:00 a.m. to 5:30 p.m. CST
800.558.7046

Madison Pharmacy
Women’s Health America, Inc.
Madison Pharmacy O C I A T E • S
A S S Associates, LLC Restore, LLC

Madison BioDiagnostics, LLC • Cyclin Pharmaceuticals, Inc.
1289 Deming Way • PO Box 259690 • Madison, WI 53725-9690
800.558.7046 • Fax 888.898.7412

We wrote the book on
hormone therapy

by Marla Ahlgrimm, R. Ph.
and
John M. Kells, with
Christine Macgeen Rodgerson

Everything you and your healthcare provider
need to know about why synthetic hormone
therapy has not worked for many women - and
“The HRT Solution
why natural hormone therapy does - is right
should be the bible of
hormone replacement here. Marla Ahlgrimm explains the difference
for any woman who is on in clear, concise terms illustrated with real-life
hormones or considering stories from patients.
taking them. Any other
approach just isn’t good The HRT Solution introduces a new approach
enough.” to hormone therapy that is natural and as
- Christine Northrup, M.D.
individual as you. Testing to assess and monitor
author of The Wisdom of
Menopause and Women’s hormone levels is combined with customized,
Bodies, Women’s Wisdom low-dose therapy using bioidentical hormones,
identical to those your body naturally
produces.

Only $14.95 plus shipping and handling
Order by phone at
800.558-7046
or online at
www.womenshealth.com/shop/catalog

Madison Pharmacy
A S S O C I A T E S

Restore® is an exclusive program of Women’s Health America, Inc.
Madison Pharmacy Associates, LLC • Restore, LLC • Madison BioDiagnostics, LLC • Cyclin Pharmaceuticals, Inc.
40 Women’s Health America 259690 • Madison, WI• 53725-9690 • 800.558.7046 • Fax 888.898.7412
1289 Deming Way • PO Box • 800.558.7046 Fax 888.898.7412 • www.womenshealth.com
REV 04-2010
Ref #: RRBKLT-02

Restoring Hormone Balance Booklet

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