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Tassos Sarampalis   1
Chapters 8 and 9




                   2
3
• Non-equivalent groups and historical controls

• Interrupted time series

• Single-case experimental designs

• Cross-lagged correlational designs

                                                  4
• Similar to real experiments
• Typically involve pre- and post-treatment
  measurements

• But:
  Without random assignment -> Groups are not
  equivalent


                                              5
also known as literature controls

• Easier
• Fewer ethical worries

But:
Caution because of selection and report bias

                                               6
14

                8
13                                 4
                7
12                                 3
                6
11                                 2
                5
10                                  1
     97   100         103         106         109
                4
                    107     110         113    116        119         122
                                   0
                                       118          120         122         124   126 7
14                                    8                             4

13                                    7                             3

12                                    6                             2
                            15
11                                    5                             1

                            12                                      0
10                                    4
     97   100   103   106    109          107 110 113 116 119 122       118   120   122   124   126

                            9


                            6


                            3


                            0
                                 95   100 105 110 115 120 125 130                               8
Lived   Died   Total   % who lived
Hospital A   790     210    1000
Hospital B   900     100    1000




                                                  9
Lived   Died   Total   % who lived
Hospital A   790     210    1000    79%
Hospital B   900     100    1000    90%




                                                  10
Lived       Died   Total   % who lived
Hospital A      790         210    1000    79%
Hospital B      900         100    1000    90%



Fair Condition and Better
                Lived       Died   Total   % who lived
Hospital A      580         10     590
Hospital B      860         30     890

Poor Condition and Worse
                Lived       Died   Total   % who lived
Hospital A      210         200    410
Hospital B      40          70     110
                                                         11
Lived       Died   Total   % who lived
Hospital A      790         210    1000    79%
Hospital B      900         100    1000    90%



Fair Condition and Better
                Lived       Died   Total   % who lived
Hospital A      580         10     590     98.3%
Hospital B      860         30     890     96.6%

Poor Condition and Worse
                Lived       Died   Total   % who lived
Hospital A      210         200    410     51.2%
Hospital B      40          70     110     36.3%
                                                         12
• A series of discreet measurements

• A clear definition of the beginning and ending
  of the treatment




                                               13
14
15
• Regular




             N+1
                                             N

• Seasonal

             Autocorrelation Coeff.




                                      0   Time lag   16
• Repeated observations, but on a single case
  (or small number of cases)




                                                17
A1          A2




B1          B2

     time

                 18
A1          A2




B1          B2

     time

                 19
A1          A2
                 Test-Retest Correlations




B1          B2

     time

                                    20
A1          A2
                 Test-Retest Correlations



                 Synchronous Correlations




B1          B2

     time

                                    21
A1          A2
                  Test-Retest Correlations



                 Synchronous Correlations


                 Cross-Lagged Correlations

B1          B2

     time

                                     22
A1          A2
                  Test-Retest Correlations



                 Synchronous Correlations


                 Cross-Lagged Correlations

B1          B2

     time

                                     23
24
Simple   = from the undivided population
Random   = every sampling unit is equally likely
           to be selected

With Replacement
Without Replacement



                                               25
Stratified = First divide population into strata
Random = In each stratum, each unit is
             equally likely to be selected

Advantage:
Reduced sampling error (improved accuracy)



                                                   26
27
28
29
30
31
32
33
34
35
36

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Psbe2 08 research methods 2011-2012 - week 7

  • 3. 3
  • 4. • Non-equivalent groups and historical controls • Interrupted time series • Single-case experimental designs • Cross-lagged correlational designs 4
  • 5. • Similar to real experiments • Typically involve pre- and post-treatment measurements • But: Without random assignment -> Groups are not equivalent 5
  • 6. also known as literature controls • Easier • Fewer ethical worries But: Caution because of selection and report bias 6
  • 7. 14 8 13 4 7 12 3 6 11 2 5 10 1 97 100 103 106 109 4 107 110 113 116 119 122 0 118 120 122 124 126 7
  • 8. 14 8 4 13 7 3 12 6 2 15 11 5 1 12 0 10 4 97 100 103 106 109 107 110 113 116 119 122 118 120 122 124 126 9 6 3 0 95 100 105 110 115 120 125 130 8
  • 9. Lived Died Total % who lived Hospital A 790 210 1000 Hospital B 900 100 1000 9
  • 10. Lived Died Total % who lived Hospital A 790 210 1000 79% Hospital B 900 100 1000 90% 10
  • 11. Lived Died Total % who lived Hospital A 790 210 1000 79% Hospital B 900 100 1000 90% Fair Condition and Better Lived Died Total % who lived Hospital A 580 10 590 Hospital B 860 30 890 Poor Condition and Worse Lived Died Total % who lived Hospital A 210 200 410 Hospital B 40 70 110 11
  • 12. Lived Died Total % who lived Hospital A 790 210 1000 79% Hospital B 900 100 1000 90% Fair Condition and Better Lived Died Total % who lived Hospital A 580 10 590 98.3% Hospital B 860 30 890 96.6% Poor Condition and Worse Lived Died Total % who lived Hospital A 210 200 410 51.2% Hospital B 40 70 110 36.3% 12
  • 13. • A series of discreet measurements • A clear definition of the beginning and ending of the treatment 13
  • 14. 14
  • 15. 15
  • 16. • Regular N+1 N • Seasonal Autocorrelation Coeff. 0 Time lag 16
  • 17. • Repeated observations, but on a single case (or small number of cases) 17
  • 18. A1 A2 B1 B2 time 18
  • 19. A1 A2 B1 B2 time 19
  • 20. A1 A2 Test-Retest Correlations B1 B2 time 20
  • 21. A1 A2 Test-Retest Correlations Synchronous Correlations B1 B2 time 21
  • 22. A1 A2 Test-Retest Correlations Synchronous Correlations Cross-Lagged Correlations B1 B2 time 22
  • 23. A1 A2 Test-Retest Correlations Synchronous Correlations Cross-Lagged Correlations B1 B2 time 23
  • 24. 24
  • 25. Simple = from the undivided population Random = every sampling unit is equally likely to be selected With Replacement Without Replacement 25
  • 26. Stratified = First divide population into strata Random = In each stratum, each unit is equally likely to be selected Advantage: Reduced sampling error (improved accuracy) 26
  • 27. 27
  • 28. 28
  • 29. 29
  • 30. 30
  • 31. 31
  • 32. 32
  • 33. 33
  • 34. 34
  • 35. 35
  • 36. 36