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Anaesthesia for
Ophthalmic Surgery
  Anatomy, Physiology and Practice
     T Mphanza FRCA, FFICM




                 1
Special Considerations

• Proximity to airway
• Age
• Anatomy
• Physiology

                        2
3
Anatomy

• Orbit - irregular pyramid
 • Base at the front
 • Axis - points postero-medially
 • Optic foramen forms the apex

                    4
Anatomy

• Orbit - irregular pyramid
 • 40 - 50 mm deep
 • Volume - 30 mls
   • globe - 7 mls

                     5
Anatomy

• Globe
 • Anteriorly
 • Closer to the roof
 • Nearer to the lateral wall
 • Axial length - 25 mm
                     6
Anatomy




   7
Anatomy

• Extraocular muscles
 • 4 rectus muscles
 • 2 oblique muscles

                    8
LR6(SO4)3


    9
Sensory Innervation

• Trigeminal
 •V  1


   •     Supratrochlear, Supraorbital, Long ciliary, Nasociliary, Infratrochlear, Lacrimal


 •V  2


   •     Infraorbital, Zygomatic




                                                         10
Autonomic Innervation
• Sympathetic
 • Superior cervical ganglion
   • Mydriasis
• Parasympathetic
 • Fibres from III
   • Miosis

                    11
12
Blood Vessels
• Arterial
 • Ophthalmic artery
• Venous
 • Ophthalmic veins
   • Superior
   • Inferior
                  13
Anatomy and
 Physiology




     14
Physiology
• Aqueous humour
 • Produced by ciliary body
   • Carbonic anhydrase
 • Drainage
   • Venous channels
     • SVC
                    15
Physiology

• Intraocular pressure (IOP)
 • Range 10 - 20 mmHg
 • Increases with age
 • Direct correlation with axial length
 • Main determinant is aqueous humour
                    16
Physiology
• Factors affecting IOP
 • Arterial BP
   • Auto-regulation
 • Venous BP
   • Valsalva, coughing, straining
 • Partial pressures - CO , O
                           2   2



                      17
Events that Decrease
         IOP
•   IV anaesthetics

•   Volatile anaesthetics

•   Mannitol

•   Timolol




                            18
Events that Increase
        IOP
•   Succinylcholine

•   Direct laryngoscopy

•   Hypoventilation




                          19
20
Oculomedullary
         Reflexes
• Oculocardiac
 • Trigemino-vagal:
   • Bradycardia, ectopics, sinus arrest
• Oculorespiratory
• Oculoemetic
                     21
Anaesthetic
 Ramifications of
Ophthalmic Drugs

        22
• Ecothiopate
 • Anticholinesterase miotic
• Cyclopentolate
 • Mydriatic
• Phenylephrine
 • Mydriatic
                    23
• Acetazolamide
 • Carbonic anhydrase inhibitor
• Timolol
 • Beta blocker
• Sulphur hexafluoride
 • Inert gas
                    24
Requirements for
Ophthalmic Surgery


        25
• Akinesia
• Profound analgesia
• Minimal bleeding
• Avoidance of oculocardiac reflex
                     26
• Control of IOP
• Awareness of drug interactions
• Emergence without coughing, straining or
  vomiting


                    27
Anaesthesia Techniques

• General
• Local
 • Topical
 • Regional

              28
Factors that Influence
Choice of Anaesthesia
• Nature and duration of procedure
• Coagulation status
• Patient’s choice
 • Ability to communicate and cooperate

                   29
General Anaesthesia


• Volatile vs TIVA
• ETT vs LMA


                     30
General Anaesthesia

• Special consideration
 • Head up tilt
 • Avoid hypercapnoea
 • Avoid N O in vitreoretinal surgery
            2


 • Smooth emergence
                    31
Topical Anaesthesia
• Instillation of LA drops
• Advantages
 • Minimal complications
• Limitations
 • Lack of akinesia
 • Only suitable for uncomplicated cases
                    32
Regional Anaesthesia

• Sub-Tenon
• Peribulbar (Extra-conal)

• Retrobulbar (Intra-conal)

                     33
Sub-Tenon’s Block

• Tenon’s capsule
 • Dense fascial sheath surrounding the
    globe and extraocular muscles from the
    limbus to the optic nerve



                    34
Sub-Tenon’s Block
• Sensory block
 • Short-ciliary nerves pass through Tenon’s
    capsule to globe
• Akinesia
 • Direct blockade of ant. nerve fibres as
    they enter extra-ocular muscles

                       35
Retro & Peribulbar
      Blocks




        36
Retrobulbar Block




        37
Complications of
     Regional Blocks
• Stimulation of oculocardiac reflex
• Haemorrhage
 • Superficial
 • Retrobulbar
• Retinal perfusion compromise
 • Loss of vision
                     38
Complications of
     Regional Blocks
• Globe penetration
• Intra-arterial injection
• Trauma to optic nerve
• Optic sheath injection

                      39
Complications of
     Regional Blocks

• Extraocular muscle injury
• Central retinal artery occlusion
• Accidental brainstem anaesthesia

                    40
Anaesthetic
Management of Specific
      Situations

          41
• Open Eye, Full Stomach
 • Aspiration vs Blindness
• Strabismus surgery
 • OCR
 • MH
 • PONV
                    42
• Intraocular Surgery
 • Glaucoma, vitrectomy, cataracts
    • IOP control
    • Complete akinesia
    • Continuation of miotics
    • Provide an antiemetic effect
                    43
• Retinal Detachment Surgery
 • SF injection for tamponade
      6



 • IV acetazolamide or mannitol
 • Akinesia is not critical

                    44
General Vs. Regional
   Anaesthesia


         45
• Regional Techniques
 • Day stay surgery
 • Better akinesia
 • Less PONV
 • Less effect on IOP
                   46
Evidence Based
         Medicine

• Cochrane Reviews
 • Peribulbar Vs. Retrobulbar
 • Sub-Tenon’s Vs. Topical

                    47
Evidence Based
     Medicine - CRTs
• General Vs Regional for Cataract Surgery
 • Cognitive Function
 • Perioperative MI
 • Plasma catecholamine response

                    48
Summary

• Anatomy and Physiology
• Drug interactions
• Special Requirements
• Management of Specific Situations

                     49

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Anaesthesia for ophthalmic surgery