This document summarizes key points from the 4th International RHINO Workshop held in Guanajuato, Mexico in March 2010. It discusses the achievements of the Health Metrics Network (HMN) Framework for strengthening country health information systems, including its global acceptance and adoption by organizations. It emphasizes that a robust health information system (RHIS) is critical for driving health system strengthening efforts. The document also stresses the importance of data architecture and making the business case for investing in RHIS by providing examples of how RHIS has saved both lives and money in different countries.