condroitin and glucosamine | chondroitin glucosamine side effects

RITMIR017: Glucosamine – A Market Insight Report, July 2013
© RI Technologies - www.researchimpact.com Sample Page - 1
GLUCOSAMINE MARKET SIZE
Scope of the Study
Glucosamine report covers the types of Glucosamine and the various Applications of Glucosamine. The
types of Glucosamine covered include D-Glucosamine and N-Acetyl-Glucosamine. The Applications of
Glucosamine include Nutraceuticals/Pharmaceuticals, Feed Additives, Food Ingredients and Other (such as
Cosmetology and Research and Development). The report provides a market analysis of each of the types
and applications by their respective categories. The study includes estimates and projections for the total
global Glucosamine market and also key regional markets that include North America, Europe, China, Asia-
Pacific (excluding China) and Rest of World. Estimates and projections are illustrated graphically.
Business profiles of 49 major companies engaged in glucosamine production and glucosamine derived
products are discussed in the report. The report serves as a guide to global Glucosamine industry, covering
more than 245 companies that are engaged in the production, development, and supply of Glucosamine.
Major glucosamine derived products are also discussed in the report. Companies producing glucosamine
derived nutritional supplements, feed additives, food ingredients, and other related products are also
mentioned. Information related to recent product releases, product developments, partnerships,
collaborations, and mergers and acquisitions is also covered in the report.
Glucosamine report is an ideal research tool providing strategic business intelligence to the corporate
sector. This report may help strategists, investors, laboratories, pharmaceutical companies, contract
research organizations, biotechnology companies and drug approval authorities in –
 Gauging Competitive Intelligence
 Identifying Key Growth Areas and Opportunities
 Understanding Geographic Relevance to Product
 Knowing Regional Market Sizes and Growth Opportunities and Restraints
 Keeping Tab on Emerging Technologies
 Equity Analysis
 Tapping New Markets
Analytics and data presented in this report pertain to several parameters such as –
 Global and Regional Market Sizes, Market Shares, Market Trends
 Product (Global and Regional) Market Sizes, Market Shares, Market Trends
 Technology Trends
 Corporate Intelligence
 Key Companies By Sales, Brands, Products
 Consumer Behavioral Patterns
 Other Strategic Business Affecting Data
Research Methodology
RI Technologies publishes business intelligence reports by going through a cycle of diligent research and
analysis activity. Research is done using both online and offline resources. The study outline of this report is
sketched on the following lines – global market analysis, regional market analysis, product segmentation,
global and regional market analysis by product segment, market trends, M&A, R&D, competitive landscape,

technology trends, and other key drivers. Current data helps in analyzing the future of the industry and is
also helpful for doing market evaluations, and estimating the market size for the future.
This report is uniquely researched and the methodology includes:
 Need and Scope of Study
 Product Definitions
 Segmental Analysis
 Regional Analysis
 Exclusive Data Analytics
 Corporate Intelligence
 Feedback
Right from concept to final compilation of this report, both primary and secondary research methods are
applied. We have provided exclusive feedback forms/pre-release questionnaires for this report to use the
information for authentication of our own findings. Secondary research includes government publications,
investment research reports, web based surveys, website information of both companies and markets, and
other offline resources such as print publications and CDs. Our compilation of easy to navigate PDF reports
are essential value addition resources for leading and growing companies.

II. REPORT SYNOPSIS
Joint Supplements
A Supplement in common terms is defined as any substance providing elements to support or build the
body, develop the potentials of the body or any task of the body, synthesize essential elements of the body,
or to provide the elements which the body is unable to synthesize or failing produce in amounts necessary.
These supplements are named depending on the site of their functioning for example joint supplements
provide energy in the junctions of the bones. Joint supplements are used as they are advantageous in
 Reconstruction of the damaged or worn out joint tissues and fluids,
 Elimination of irritations and pain causing poisons from the body and
 As an analgesic which decreases the pain in the joints of the patients.
The joint supplement is designed or developed keeping in view that it not only helps the reconstruction of
the joints but also relieves the patient from pain and removes the toxins causing allergies and other
detrimental effects. The supplements should not only provide relief to the patients but also should be
helpful in repairing the damaged tissue and in the process should not harm the patient. Supplements now
are taking a significant place in the diet of the humans and animals due to the numerous and changed life
styles adapted in the present living systems. The choice of the supplement should be done depending on
the
 Requirement of the body
 Ingredients of the supplement
 Properties of the ingredients present in the supplement
 Production conditions of the supplements and
 Company synthesizing the supplements.
The choice could be simple if one chooses the supplements to relieve pain and which cause no effects
during the course of their use. Steroids, NSAIDs or other medications give a temporary relief to the patient
but on continuous use cause adverse effects on the other organs of the body. So, the use of steroids,
NSAIDs or other medications as supplements should be avoided. In some cases, the use of the stronger
NSAIDs or prescription arthritis medications becomes necessary and unavoidable. In such situations, the
combined use of the stronger NSAIDs or prescription arthritis medications along with the joint supplements
would reduce the risk of damage of other organs and accumulation of toxins in the body. The performance
of the drug to cure the patient would also increase. Not always the mixing of the drug and the joint
supplement provide the cure to the patient but the combination may sometimes result in chemical
reactions between them causing harm to the patient.

Glucosamine
Glucosamine is a material that naturally occurs in the joints of the body. It is synthesized by the body from
glucose (sugar) and glutamine. Glucosamine helps in making and repairing cartilage in the body. As humans
grow old, the ability of the body to produce Glucosamine from glucose and glutamine also declines due to a
decrease in the enzyme that aids production of Glucosamine. When Glucosamine Sulfate is not available in
sufficient quantities, there is a degeneration of the cartilage. Glucosamine supplements could restore the
Glucosamine levels in the body and also repair joints that are destroyed by osteoarthritis or other wounds.
Glucosamine is present in five different forms:
 D-Glucosamine Hydrochloride (HCl)
 D-Glucosamine Sulphate (2 molecules of KCl)
 D-Glucosamine Sulphate NaCl
 N-Acetyl-Glucosamine (NAG)
 Poly N-Acetyl-Glucosamine (Poly NAG)
The IUPAC name for Glucosamine is “D-Glucosamine”. This name is not valid for N-Acetyl-Glucosamine
(NAG) and Poly N-Acetyl-Glucosamine (Poly NAG).
Segmentation of Glucosamine
Exhibit 1. Segmentation of Global Glucosamine Market by Type and by Application
Type Application
D-Glucosamine Nutraceuticals/Pharmaceuticals
N-Acetyl-Glucosamine Feed Additives
Food Ingredients
*Other
*Other includes Cosmetology, Research and Development
© RIT, 2013

Global Market Analysis
Global Market for Glucosamine is estimated at US$ XX.XX billion in 2012 and is projected to reach US$
XX.XX billion by 2020 growing at a CAGR of XX.XX % during the analysis period (2000-2020).
Exhibit 2. Glucosamine – Global Value Market Historic Analysis (2000-2005) in US$ Million
Year Value
2000 XX.XX
2001 XX.XX
2002 XX.XX
2003 XX.XX
2004 XX.XX
2005 XX.XX
CAGR% XX.XX
© RIT Figures, 2013
2000 2001 2002 2003 2004 2005
US$ Million

Exhibit 3. Glucosamine – Global Value Market Estimations & Predictions (2005-2020) in US$ Billion
Year Value
2005 XX.XX
2006 XX.XX
2007 XX.XX
2008 XX.XX
2009 XX.XX
2010 XX.XX
2011 XX.XX
2012 XX.XX
2013 XX.XX
2014 XX.XX
2015 XX.XX
2016 XX.XX
2017 XX.XX
2018 XX.XX
2019 XX.XX
2020 XX.XX
CAGR% XX.XX
2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020
US$ Billion

III. MARKET DYNAMICS
Market Overview
Glucosamine based products were classified as nutraceuticals in most countries worldwide. But now a
number of countries (especially Europe) are permitting glucosamine products to be registered as
pharmaceuticals.
Products sold as drugs need to be approved by national medicines agencies, whereas nutraceuticals in
general are governed by much less demanding food regulations.
As a result of the US anti-dumping action against shrimp shells from India and the EU ban on seafood
imports from China, there was a steep rise in the price of Glucosamine.
But since the uplift of the ban price of glucosamine has more or less stabilized. Change in the status of
Glucosamine from drug to food has led to the market being opened up. Since its entrance on the food
market, glucosamine has tripled in sales
The recommended dose of glucosamine is 1,500mg. Putting that level into food may cause an issue, due to
its taste and also the expense.
Coca-Cola branched out into glucosamine in the US with fortified juice Minute Maid Active, while Smooth
Walking, an energy drink aimed at people over 40 who want to keep agile, was launched in Japan.
However, glucosamine fortified drinks haven't seen much success in Europe. In 2005 Complan Active, a
glucosamine fortified juice for seniors, was discontinued.
Delamere Dairy's Top Life Prime Time goat's milk fortified with glucosamine and chondroitin met a similar
fate in 2007, after just a year on the market.
Growth of the Glucosamine market is bound to continue, mainly driven by the following three factors:
 More number of countries are permitting the registration of glucosamine based drugs
 Increasing usage of glucosamine in the treatment of Osteoarthritis
 There is a constant increase in occurrence of Osteoarthritis mainly due to the ageing population
Glucosamine supplements have witnessed healthy sales worldwide. But with a constant stream of new
products saturating the market, manufacturers are starting to consider new applications for the amino
sugar and have found the food industry the most promising.
The introduction of combination products such as Vitabiotics' Jointace [supplement] with collagen,
glucosamine and chondroitin are undercutting sales for single glucosamine dietary supplements on the
market.

Global Market Analysis
Global Glucosamine market in terms of volume was reported at about XX.XX thousand metric tons in 2012.
The market during 2000 -2020 grew at a CAGR of XX.XX % to reach XX.XX thousand metric tons in 2020.
Exhibit 4. Glucosamine – Global Volume Market Analysis (2000-2005) by Geographic Region for North
America, Europe, China, Asia-Pacific and Rest of World in Metric Tons
Year/Region North America Europe China Asia-Pacific Rest of World Total
2000 XX.XX XX.XX XX.XX XX.XX XX.XX XX.XX
CAGR% XX.XX XX.XX XX.XX XX.XX XX.XX XX.XX
2000 2001 2002 2003 2004 2005
US$ Million
North America Europe China Asia-Pacific Rest of World

Exhibit 5. Glucosamine – Global Volume Market Analysis (2005-2020) by Geographic Region for North
America, Europe, China, Asia-Pacific and Rest of World in Metric Tons
2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020
US$ Million
North America Europe China Asia-Pacific Rest of World

Exhibit 6. Glucosamine – Global Volume Market Shares (2000, 2015 &2020) by Geographic Region for
North America, Europe, China, Asia-Pacific and Rest of World in Metric Tons

Analysis by Type
D-Glucosamine market is the largest type globally and is estimated at US$XX.XX billion in 2012 with a
market share of XX.XX % (2012) and is forecast to reach US$ XX.XX billion by 2020 with a CAGR of XX.XX %.
N-Acetyl is the faster growing with a CAGR of XX.XX % during the analysis period.
Exhibit 7. Glucosamine -Global Value Market Estimations & Predictions (2000-2005) by Type for D-
Glucosamine and N-Acetyl-Glucosamine in US$ Million
Year/Type D-Glucosamine N-Acetyl Glucosamine Total
2000 XX.XX XX.XX XX.XX
CAGR% XX.XX XX.XX XX.XX
2000 2001 2002 2003 2004 2005
US$ Million
D-Glucosamine N-AcetylGlucosamine

Exhibit 8. Glucosamine -Global Value Market Estimations & Predictions (2005-2020) by Type for D-
Glucosamine and N-Acetyl-Glucosamine in US$ Million
2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020
US$ Million
D-Glucosamine N-AcetylGlucosamine

Exhibit 9. Glucosamine -Global Value Market Shares (2000, 2015 &2020) by Type for D-Glucosamine and
N-Acetyl-Glucosamine in US$ Million
IV. PRODUCT TECHNOLOGY/RESEARCH
Exhibit 10. List of Available Glucosamine based Drugs
Trade Name Company Composition Indication
AB AUSBIOBONE Max Biocare Pty. Ltd.
(Australia)
Glucosamine Sulfate,
Chondroitin Sulfate-shark &
Manganese
Arthritis, Osteoarthritis,
Rheumatism, Gout & Back Pain
AB Carsa Giox Max Biocare Pty. Ltd.
(Australia)
Ginger, Glucosamine &
Chondroitin Sulfate
Low Back pain, Osteoarthritic Pain,
Rheumatism & Osteoarthritis
AB GLUCOSAMINE Max Biocare Pty. Ltd.
(Australia)
Glucosamine Sulfate
Potassium Chloride Complex
Arthritis, Gout & Rheumatism
AB ORIOSTIN Max Biocare Pty. Ltd.
(Australia)
Glucosamine Sulfate, Ginger
& Manganese
Arthritis, Osteoarthritis,
Rheumatism, Gout & Back Pain
More……
© RIT, 2013

GLUCOSAMINE - THE OUTLOOK
Glucosamine is the most sought after product in terms of joint health. It may not be a complete cure for
Osteoarthritis, but with mounting scientific proof and some of the world's leading manufacturers behind it,
there could be a good profit in the glucosamine functional food market. The application of Glucosamine in
other fields such as body building, wound healing, inflammatory bowel disorders, cosmetology, etc. has
considerably increased the need and production of Glucosamine. Consumer demand for dietary
supplements is growing stronger more than before, thereby crossing demographic lines and expanding
market opportunities for brand owners across a wide range of products. Consumers look towards low-cost,
anti-medical, general well being products more than drugs.
Moreover, supplement manufacturers are now required to follow Current Good Manufacturing Practices
(CGMP), the federal regulations that are typically associated with the manufacture of drug products. This is
considered as a major shift for glucosamine manufacturers. Also, manufacturers should conduct full testing
on all active ingredients in multi-active products, as per a new regulation. Contract manufacturers and
brand owners of glucosamine products need to collaborate closely to develop and manufacture high-
quality products that meet consumer demand while maximizing profits. Researchers are still having
debates on the success of glucosamine and chondroitin remedies for osteoarthritis. Glucosamine is largely
utilized in the formation and repair of the cartilage while chondroitin is responsible for the durability and
sturdiness of the cartilage.
Global Market for Glucosamine is estimated at US$XX.XX billion in 2012 and is projected to reach US$ XX.XX
billion by 2020 growing at a CAGR of XX.XX % during the analysis period (2005-2020). Global volume market
for Glucosamine was reported at US$ XX.XX thousand metric tons in 2000. The market reached XX.XX
thousand metric tons in 2005 growing at a CAGR of XX.XX %.
Glucosamine application in Nutraceuticals/Pharmaceuticals is the leading market segment globally valued
at about US$ XX.XX billion in 2010 and is forecast to reach US$ XX.XX billion by 2020 with a market share of
XX.XX % (2020). Food Ingredients is the fastest growing application of Glucosamine with a CAGR of XX.XX %
closely followed by Other applications (XX.XX %) and Feed Additives (XX.XX %) during the analysis period
2005-2020.
Globally, glucosamine products have seen about 50% increase in launches in the past five years. The
leading markets include Asia Pacific, Europe and North America. In the future, many functional food
products would come out in less developed regions of the Latin America and Asia Pacific…….
About RI Technologies
RI Technologies is a premier source of market research on the Biotechnology & Healthcare sector. We
emphasize on factual insights and forecasts with maximum global coverage. RI Technologies is constantly
monitoring the biotechnology & Healthcare industry, tracking market trends, and forecasting industry
based on specialized analysis. The life sciences sector is an ever growing marketplace with emerging
technologies in areas of discovery, design and development.
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 Gauging Competitive Intelligence
 Identifying Key Growth Areas and Opportunities
 Understanding Geographic Relevance to Product
 Knowing Regional Market Sizes and Growth Opportunities and Restraints
 Keeping Tab on Emerging Technologies
 Equity Analysis
 Tapping New Markets
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