Amino acids market research report

RITMIR016: Amino Acids – A Market Insight Report, July 2013
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AMINO ACIDS MARKET SIZE
Scope of the Study
Amino Acids report covers the types of Amino Acids and the various Applications of Amino Acids in the
market. The types of Amino Acids covered include Glutamate, Methionine, Lysine, Branched Chain Amino
Acids, Phenylalanine and Other (such as Tryptophan, Threonine etc). The Applications of Amino Acids
include Feed Additives, Food Ingredients, Nutraceutical/Pharmaceutical and Other (such as Anti-aging
Therapy, Cosmetology and Research and Development). The report provides an in depth analysis of each of
the types and applications by their respective categories. The study includes estimates and projections for
the total global Amino Acids market and also key regional markets that include North America, Europe,
China, Asia-Pacific (excluding China), Latin America and Rest of World. Estimates and projections are
illustrated graphically.
Business profiles of 11 global major companies and 73 competitor companies are discussed in the report.
The report serves as a guide to global Amino Acids industry, covering more than 500 companies that are
engaged in the development and supply of Amino Acids. Information related to recent product releases,
product developments, partnerships, collaborations, and mergers and acquisitions is also covered in the
report.
Amino Acids report is an ideal research tool providing strategic business intelligence to the corporate
sector. This report may help strategists, investors, laboratories, pharmaceutical companies, contract
research organizations, biotechnology companies and drug approval authorities in –
 Gauging Competitive Intelligence
 Identifying Key Growth Areas and Opportunities
 Understanding Geographic Relevance to Product
 Knowing Regional Market Sizes and Growth Opportunities and Restraints
 Keeping Tab on Emerging Technologies
 Equity Analysis
 Tapping New Markets
Analytics and data presented in this report pertain to several parameters such as –
 Global and Regional Market Sizes, Market Shares, Market Trends
 Product (Global and Regional) Market Sizes, Market Shares, Market Trends
 Technology Trends
 Corporate Intelligence
 Key Companies By Sales, Brands, Products
 Consumer Behavioral Patterns

 Other Strategic Business Affecting Data
Research Methodology
RI Technologies publishes business intelligence reports by going through a cycle of diligent research and
analysis activity. Research is done using both online and offline resources. The study outline of this report is
sketched on the following lines – global market analysis, regional market analysis, product segmentation,
global and regional market analysis by product segment, market trends, M&A, R&D, competitive landscape,
technology trends, and other key drivers. Current data helps in analyzing the future of the industry and is
also helpful for doing market evaluations, and estimating the market size for the future.
This report is uniquely researched and the methodology includes:
 Need and Scope of Study
 Product Definitions
 Segmental Analysis
 Regional Analysis
 Exclusive Data Analytics
 Corporate Intelligence
 Feedback
Right from concept to final compilation of this report, both primary and secondary research methods are
applied. We have provided exclusive feedback forms/pre-release questionnaires for this report to use the
information for authentication of our own findings. Secondary research includes government publications,
investment research reports, web based surveys, website information of both companies and markets, and
other offline resources such as print publications and CDs.
Our compilation of easy to navigate PDF reports are essential value addition resources for leading and
growing companies.

II. REPORT SYNOPSIS
Every living being in the universe needs protein to grow. While it is true that water contributes to the
largest percentage of body weight, protein is also an important contributory factor to it. This is because
protein is present in every organ and muscle of the body. Protein that is present in the body does not come
only from food that is ingested. In fact ingested protein is first broken down into amino acids that are then
broken down into specific proteins necessary for growth.
Enzymes and hormones present in the body that are responsible for specific body functions are also
proteins. Amino acids are required by the body to carry out different functions that even include the
functioning of the brain. Proteins are also responsible for activation and utilization of other macro and
micro nutrients in the body.
The amino acid can be described as a group of organic molecules that comprise of an organic R group or a
side chain, which presents a solitary characteristic to the amino acid, an acidic carboxyl group represented
as -COOH and a basic amino group represented as -NH2. If two or more amino acids combine the
combination is known as a peptide.
Proteins are made up of chains of amino acids that are linked and attached to each other with peptide
bonds. There are twenty-eight such amino acids that play a vital role in maintaining the human body. While
the body receives about twenty percent of these amino acids from the diet known as essential amino acids,
eighty percent are made in the body itself known as non-essential amino acids. The liver is the organ
responsible for the manufacture of these amino acids.
All amino acids work together to provide the body with a continuous supply of nutrients that are necessary
for it to carry out its functions. When the body does not receive sufficient amino acids from the food eaten,
it affects its functioning leading to poor health.
On the other hand too much protein in the body is also harmful. As the body makes its own proteins, a by-
product called ammonia is also produced in the liver as a waste product. Too much protein in the body
results in high amount of ammonia as well. The kidneys and liver then have to work harder to flush this
excess ammonia out of the body.
Today amino acids can be taken as a supplement that is available commercially. Amino acid supplements
are usually made from animal protein, vegetable protein, or yeast. While almost all amino acids can be
produced in two forms – the L and D form, it is not so in the case of glycine. L and D basically refer to
manner in which the amino acid is wound up. L is the left winding amino acid and D is the right winding
amino acid. Human amino acids have been found to be the L type and this is usually the preferred
supplement as well.
Importance of Amino Acids
In dietary supplement programs amino acids are added and given due importance. Amino acids are said to
be the building blocks for good health as they are comprised of essential proteins. Conversely it could be
pointed out that the very existence of proteins is dependent on the specific combination of amino acids.
When amino acids get reduced or are found to be missing, there is a commensurate reduction in the

effectiveness of other amino acids. The human body requires sufficient protein intake for almost every bit
of development. It could be for healthy body fluids, hair growth, nails, glands, organs, tendons, ligaments
and strong muscles. The maximum part of a person’s body weight after water is seen to be protein, hence it
could be concluded that for the maintenance of good health the body needs proteins. It could also be
reiterated that the CNS is unable to perform efficiently if amino acids are absent. The brain requires amino
acids for the receipt and dispatching of information. It could be emphasized that each cell in the human
body contains protein. The body’s dry weight consists of proteins to an extent of 50%. Protein is present in
hormones and enzymes. In fact blood, cartilage, bone and muscle are all comprised of a good amount of
proteins. Proteins help the muscles to hold water and are essential for contraction. Skin and hair are
provided with a protective coating. Bones and teeth attain their robustness through proteins. Proteins help
in the regeneration of tissue. The water content and acid-balance is regulated through the presence of
proteins. Antibodies are also produced in the body with the help of proteins.
Segmentation of Amino Acids
Exhibit 1. Segmentation of Amino Acids Market by Type and Application
Type Application
Glutamate Feed Additives
Methionine Food Ingredients
Lysine Nutraceutical/Pharmaceutical
Branched Chain Amino Acids *Other (2)
Phenylalanine
*Other (1)
* (1) Other includes Tryptophan, Threonine, etc.
* (2) Other includes Anti-Aging, Cosmetology, and Research and Development.
© RIT, 2013

Global Market Analysis
Value Market Analysis
Global Amino Acids market is projected to reach about US$XX.XX billion by 2020 from an estimated US$
XX.XX billion in 2012, growing at a compounded annual growth rate (CAGR) of XX.XX% during the analysis
period 2000-2020.
Exhibit 2. Amino Acids (2000-2010) – Global Market Analysis (Historic, Current & Future) in US$ Billion
Year Value
2000 XX.XX
2001 XX.XX
2002 XX.XX
2003 XX.XX
2004 XX.XX
2005 XX.XX
2006 XX.XX
2007 XX.XX
2008 XX.XX
2009 XX.XX
2010 XX.XX
CAGR% XX.XX
© RIT Figures, 2013
2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010
US$ Billion

Exhibit 3. Amino Acids (2011-2020) – Global Market Analysis (Historic, Current & Future) in US$ Billion
Year Value
2011 XX.XX
2012 XX.XX
2013 XX.XX
2014 XX.XX
2015 XX.XX
2016 XX.XX
2017 XX.XX
2018 XX.XX
2019 XX.XX
2020 XX.XX
CAGR% XX.XX
2011 2012 2013 2014 2015 2016 2017 2018 2019 2020
US$ Billion

Volume Market Analysis
Global volume of Amino Acids is projected to reach about XX.XX million metric tons by 2020 from an
estimated XX.XX million metric tons in 2012, growing at a compounded annual growth rate (CAGR) of
XX.XX% during the analysis period 2000-2020.
Exhibit 4. Amino Acids (2000-2010) – Global Volume Analysis (Historic, Current & Future) in Thousand
Metric Tons
Year Volume
2000 XX.XX
2001 XX.XX
2002 XX.XX
2003 XX.XX
2004 XX.XX
2005 XX.XX
2006 XX.XX
2007 XX.XX
2008 XX.XX
2009 XX.XX
2010 XX.XX
CAGR% XX.XX
2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010
US$ Million

Exhibit 5. Amino Acids (2011-2020) – Global Volume Analysis (Historic, Current & Future) in Thousand
Metric Tons
Year Volume
2011 XX.XX
2012 XX.XX
2013 XX.XX
2014 XX.XX
2015 XX.XX
2016 XX.XX
2017 XX.XX
2018 XX.XX
2019 XX.XX
2020 XX.XX
CAGR% XX.XX
2011 2012 2013 2014 2015 2016 2017 2018 2019 2020
US$ Million

III. MARKET DYNAMICS
MARKET OVERVIEW
Market Growth Factors
There has been a substantial increase in the demand for amino acids in the last thirty years or so. There is a
steady 5-10% growth rate in the market. It is estimated that in that last ten years the market demand for
amino acids has doubled. L-lysine, which is used as an additive in animal feed, has shown a sharp increase
in demand. It is estimated that the global market for L-lysine has increased almost 20 times in the past
twenty years. There are other amino acids that are now available in the market such as L-threonine, L-
aspartate and L-phenylalanine. Specifically, L-aspartate and L-phenylalanine are used for the synthesis of a
sweetener known as Aspartame.
Among the amino acids available in the market, L-Glutamate is still the most popular one followed by L-
lysine and D,L-methionine.
The prices of amino acids are often affected by the dynamics in the market. The increase in the efficiency of
the fermentation technology can lead to the development of cheaper goods and thereby increase the
overall demand. Subsequently, there is bound to be large-scale production of these products which will
lower the costs even more. However, despite these trends in the market, the supply of amino acids such as
L-lysine to be used as feed additives will compete with soybean meal which is a natural source of L-lysine.
Therefore, there are bound to be fluctuations in the market demand for amino acids based on the yield of
crops. The quantity of production of amino acids is also a determinant of its cost. Amino acids that are
produced on a large-scale are bound to be inexpensive. The price factor also plays a role in the location of
the production plants. The location of the production plants is governed by the chief dynamics of price of
the carbon source and the local market. There are large L-glutamate production plants in different parts of
the world specifically in the countries of the Far East such as Thailand and Indonesia. However, as far as the
location of the production plants of L-lysine are concerned, the situation is different. Since one-third of the
global market for this product is concentrated in North America, one-third of the L-lysine production plants
are located there. The location of these plants in this area is also driven by the availability of maize as a
feedstock material for the process of fermentation. Most of the time, the companies that are producers of
L-lysine are linked to the maize milling industry in various capacities either as producers, in joint ventures or
as suppliers of cheap sugar. This is indicative of the fact that commercialization of amino acid production is
undergoing rapid change and growth under the influence of the various global interactions.
Presently more and more people are making use of amino acids to maintain their figure. Beauty conscious
people such as fashion models are resorting to them. It can be thus seen that amino acids do have an
immense potential in the area of body fitness programs. There is an increasing trend at present to
incorporate amino acids in body soaps, rinses and shampoos. Such products that contain amino acids do
certainly have advantages to improve the general fitness of the body.
Global Volume of Amino Acids is projected at XX.XX million metric tons in 2020 from an estimated XX.XX
million metric tons in 2012. China is the largest producer of Amino Acids with an estimated volume of XX.XX
million metric tons in 2012. Latin America is projected to have the highest growth rate (XX.XX %) during the
analysis period (2005-2020).

Exhibit 6. Amino Acids (2000-2010) – Global Volume Analysis (Historic, Current & Future) by Geographic
Region for China, North America, *Asia-Pacific, Europe, Latin America and Rest of World in Thousand
Metric Tons
Year/Region China North America Asia - Pacific Europe Latin America Rest of World Total
2000 XX.XX XX.XX XX.XX XX.XX XX.XX XX.XX XX.XX
CAGR% XX.XX XX.XX XX.XX XX.XX XX.XX XX.XX XX.XX
*Excludes China
2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010
US$ Million
China North America Asia - Pacific Europe Latin America Rest of World

Exhibit 7. Amino Acids (2011-2020) – Global Volume Analysis (Historic, Current & Future) by Geographic
Region for China, North America, *Asia-Pacific, Europe, Latin America and Rest of World in Thousand
Metric Tons
*Excludes China
2011 2012 2013 2014 2015 2016 2017 2018 2019 2020
US$ Million
China North America Asia - Pacific Europe Latin America Rest of World

Exhibit 8. Amino Acids (2000, 2015 & 2020) – Global Volume Market Shares (Historic, Current & Future)
by Geographic Region for China, North America, *Asia-Pacific, Europe, Latin America and Rest of World
in Thousand Metric Tons

Demand Analysis
Global demand for Amino Acids was US$ XX.XX billion in 2012 in terms of value and slightly more than
XX.XX million lbs in terms of quantity. Demand for Amino Acids is projected to increase to US$ XX.XX billion
in 2020 and XX.XX million lbs in terms of quantity.
Exhibit 9. Amino Acids– Global Demand Analysis (2000-2010) in US$ Billion and in Million Lbs
Year Demand in US$ Billion Demand in Million lbs
2000 XX.XX XX.XX
2001 XX.XX XX.XX
2002 XX.XX XX.XX
2003 XX.XX XX.XX
2004 XX.XX XX.XX
2005 XX.XX XX.XX
2006 XX.XX XX.XX
2007 XX.XX XX.XX
2008 XX.XX XX.XX
2009 XX.XX XX.XX
2010 XX.XX XX.XX
CAGR% XX.XX XX.XX
2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010
US$ Billion
Medical Research Agriculture/AnimalHusbandry

Exhibit 10. Amino Acids– Global Demand Analysis (2011-2020) in US$ Billion and in Million Lbs
2011 XX.XX XX.XX
2012 XX.XX XX.XX
2013 XX.XX XX.XX
2014 XX.XX XX.XX
2015 XX.XX XX.XX
2016 XX.XX XX.XX
2017 XX.XX XX.XX
2018 XX.XX XX.XX
2019 XX.XX XX.XX
2020 XX.XX XX.XX
CAGR% XX.XX XX.XX
2011 2012 2013 2014 2015 2016 2017 2018 2019 2020
US$ Billion
Medical Research Agriculture/AnimalHusbandry

Exhibit 11. Amino Acids– Global Demand Market Shares (2000, 2015 & 2020) in US$ Billion and in Million
Lbs
2000 XX.XX XX.XX
2015 XX.XX XX.XX
2020 XX.XX XX.XX
CAGR% XX.XX XX.XX

IV. PRODUCT/TECHNOLOGY RESEARCH
Exhibit 12. List of Amino Acids by Application, Method of Production and Production in Tons/Year (2006)
Application Amino Acid Method of Production Production in Tons/Year
Feed Additives Lysine Fermentation XX.XX
Methionine Chemical Synthesis XX.XX
Threonine Fermentation XX.XX
Tryptophan Fermentation XX.XX
Food Ingredient Glutamate Fermentation XX.XX
Glycine Chemical Synthesis XX.XX
Aspartate Enzymatic Catalysis XX.XX
Phenylalanine Fermentation XX.XX
Cysteine Fermentation, reduction XX.XX
Alanine Fermentation, Extraction XX.XX
Pharmaceutical Cystine Fermentation, Extraction XX.XX
Arginine Fermentation, Extraction XX.XX
Leucine Fermentation, Extraction XX.XX
Valine Fermentation, Extraction XX.XX
Isoleucine Fermentation, Extraction XX.XX
(Source- Research Centre Jülich, Germany)
Segmentation by Application
Feed Additives
Amino Acids in Animal Nutrition
Intensive research is being carried on in the realm of nutrition of farm animals and amino acid metabolism.
In 1994 a book was published entitled Amino Acids in Farm Animal Nutrition. During the period since its
publication a lot of progress has been made and now the subject of amino acid nutrition encompasses a
more comprehensive outlook. It now recognizes a more wide range of animals which includes companion
animals. In the latest version of the book the addition of more chapters renders strength to the first version
and the introduction of articles by authors brings fresh vision and concepts on pets such as dogs and cats.
The thematically organized book has an addition of chapters by way of a general nature and in the
introduction part of the book. Several animal species have been covered and the chapters give a new
perspective to animals that include ruminants, poultry and pigs.
Food Ingredients
Monosodium Glutamate
Glutamate is a free amino acid found in ample quantities within the cytoplasm of bacteria. Despite this, the
glutamate producers need to ensure that glutamate produced by the bacteria is more than the quantities

that are required for normal metabolic activities of the bacteria, and the bacteria eventually excretes this
excess amount of glutamate into the culture broth. Even though researchers have put in forty years to
understand the mechanism that prompts C. glutamicum to produce and excrete glutamate, the exact
mechanism of the bioprocess is yet to be understood clearly. This research has, however, indicated
involvement of some specific physiological reactions in the process. These traits include a conspicuous
reduction in α- ketoglutarate dehydrogenase activity during production of glutamate, biotin auxotrophy of
glutamate producing strains of bacteria, and increased tendency of the bacteria for exporting glutamate,
possibly through a specific transporter.
MSG - Industrial Production Process
MSG is produced through various processes by industries. The processes differ in each company
manufacturing MSG. These processes are exclusive and proprietary in nature. There are a few general
patterns in these processes. A fed-batch type process is used most often. Fermentation forms an integral
part of this process. Sugar is added when the fermentation process is on, unlike in batch process, where all
ingredients are present when the process starts.
Other
Anti-aging Effect of Amino Acids
The craze for anti-aging solutions that make a person look younger has increased of late. Consequently,
combat against premature aging has been in the forefront in cosmetology research. A range of products are
in the market including age reversing skin creams, collagen fillers, anti-wrinkle solutions, and many more to
give them a face lift. Recent findings by researchers associated with skin care industry indicate that certain
amino acids may prove to be effective in anti-aging. The latest product available for consumers is amino
acid formulations that can combat aging process. But consumers of these varieties of skin care products
containing amino acids must take enough precaution to discriminate between good and poor quality
products. Some have been developed after intense research, while others are not.
Amino Acids in Cosmetology
There is an increasing trend at present to incorporate amino acids in body soaps, rinses and shampoos.
Such products that contain amino acids do certainly have advantages to improve the general fitness of the
body. Therefore the importance of amino acids in cosmetics is heartening to women.
Among NMFs or natural moisturizing factors amino acids do find an important niche. As the epidermal cells
die they turn into the stratum corneum. Thus the proteins in the cells suffer degradation to amino acids
and get moved to the stratum corneum. Approximately 50% of the NMF in the skin is comprised of amino
acids and PCA or pyrrolidone carboxylic acid. PCA is extracted from glutamate which is an amino acid.
The cosmetic ingredient known as collagen is said to contain several various amino acids and is thus the
product of choice to keep the skin moisturized and supple.
Amino Acids and Environment
Soaps and detergents are used and the discharge finds its way into sewage. This needs to be biodegradable.
Even if the discharge is pumped into rivers, lakes or sea it will not cause harm to the environment as long as
microorganisms consume and degrade them into water and carbon dioxide. Amino acids are components

of living matter and can easily return to nature. Of late detergents are being manufactured by conjugating
fatty acids to amino acids. The amino acids like glycine and glutamate are processed and are being used
extensively.
In the modern world, amino acid-derived materials are entering rapidly into the everyday life of the
common man.
Amino Acid Supplements
Under certain conditions, taking supplements containing amino acids becomes essential. They are usually
available commercially in combination with multivitamin formulas. These amino acids are prepared in the
pharmaceutical industry by hydrolyzing animal protein, vegetable protein, or yeast protein. The amino acid
supplements should be in L-forms as found in the body. However, taking such amino acid formulations
should not be continued for a prolonged period. Preferably, one can take them for two months, discontinue
for the next two months, and then resume. This is, according to researchers, to avoid accumulation of
certain amino acids to toxic levels. Therefore, the amino acid supplements should be taken only as per the
specific directions of one’s physician. It is also important that such amino acid supplements should not be
administered to a child.
Amino acids that are present in their free form do not require digestion and are absorbed immediately into
the body. However, this is not the case with amino acids that are taken as a supplement. When taking
amino acid supplements it is best to take vitamin C or ascorbic acid and vitamin B 6 as well, as these
vitamins aid in the absorption of the amino acid.
Another factor to be noted is that amino acid supplements must not be taken in large doses, as this could
result in toxicity thereby causing harm to the body. This is so particularly in the case of aspartic acid,
homocysteine, serine, glutamic acid, and tryptophan.
Other Amino Acids are:
 Acetyl L Carinitine Arginate
 Alpha-aminoadipic acid
 Alpha-amino-N-butyric acid
 Beta-alanine
 Beta-amino-isobutyric acid
 Carnosine is a potent antioxidant
 The amino acid known as citrulline was first isolated from the watermelon and is available as citrulline
amino acid supplement in the market. It derives its name from the Latin word citrullus which means
watermelon.
 The gamma-amino butyric acid also known as GABA acts as a neurotransmitter and inhibits the nerve
cells from getting excessively roused. This brings about a relaxed feeling to the mind and it is advisable
to take it when the stomach is empty. In many neurological disorders and for the modulation of
networks in the hindbrain, midbrain and forebrain the need is seen of GABAergic neurotransmission.
 hydroxyproline

 1-methylhistidine
 3-methylhistidine
 The N Acetyl L Cysteine is also an amino acid and it is available as a supplement in the market.
 Ornithine
 PABA or Para-aminobenzoic acid is also considered a B vitamin.
 phosphoserine
INDUSTRY OUTLOOK
Global Amino Acids market is projected to reach about US$XX.XX billion by 2020 from an estimated US$
XX.XX billion in 2012, growing at a compounded annual growth rate (CAGR) of XX.XX % during the analysis
period 2000-2020. Global volume of Amino Acids is projected to reach about XX.XX million metric tons by
2020 from an estimated XX.XX million metric tons in 2012, growing at a compounded annual growth rate
(CAGR) of XX.XX% during the analysis period 2000-2020.
China, the leading market (XX.XX% of global market share in 2020) for Amino Acids presently is projected to
manage the leading position during the analysis period with its share dropping to XX.XX% by 2020. North
America is the fastest growing (almost 8% during 2000-2020) market for Amino Acids, and is projected to
gain dominance over China by the end of the analysis period.
The production of amino acids in the laboratories using different biotechnological techniques marks the
development and coordination of science and technology. The demand for amino acid production is huge
and constant improvement in the field is always desired for cost effective and high yield production
strategies. The new findings like the existence of specific export carriers or cyclic fluxes within the
anapleurotic reactions are to be exploited maximum for better production of the amino acid. The strain
development, the fermentation process and the new science of metabolic engineering are to be closely
coordinated for the advantageous production of the amino acid from the available sources….
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 Understanding Geographic Relevance to Product
 Knowing Regional Market Sizes and Growth Opportunities and Restraints
 Keeping Tab on Emerging Technologies
 Equity Analysis
 Tapping New Markets
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