Unilife Corp. (NASDAQ: UNIS; Stock Twits: $UNIS) is a U.S.-based medical device company focused on the design, development, manufacture and supply of a proprietary range of retractable syringes. Primary target customers for Unilife products include pharmaceutical manufacturers, suppliers of medical equipment to healthcare facilities and patients who self-administer prescription medication.

1. Innovative Drug Delivery Device Solutions Alan Shortall Chief Executive Officer Jefferies Global Healthcare Conference June 6, 2011

2. Cautionary Note Regarding Forward-Looking Statements This presentation contains forward looking statements under the safe harbor provisions of the US securities laws. These forward-looking statements are based on management’s beliefs and assumptions and on information currently available to our management. Our management believes that these forward-looking statements are reasonable as and when made. However you should not place undue reliance on any such forward looking statements as these are subject to risks and uncertainties. Please refer to our press release and our SEC filings for more information regarding the use of forward looking statements. 2

3. 3 Introducing Unilife An emerging global leader for innovative drug delivery devices Developedfullsafetysyringeportfoliowithbest-in-classfeatures Unifill–the world’s only prefilled syringes with integrated safety Game-changer for the fastest growing, most-profitable syringe market Sanofi-aventispaid$40MMupfrontforaccess rights intwoclasses Discussions accelerating with many other interested companies Industrialization ahead of schedule, initial sales commence in July Device portfolio now rapidly expanding, driven by customer need Highly responsive business structure with a world-class team

4. Our Business Strategy Built upfront the operational capabilities to meet pharmaceutical device demands from clinical development to commercial sales Addressing unmet customer needs with innovation and speed Lead with Unifill, then expand into other advanced device areas Focus on customized, differentiated (non-commodity) devices Collaborating with our partners to develop the right device to deliver the right drug to the right patient, resulting in: Long-term, preferred source supply contracts with high-margins Revenue generating opportunities extending beyond product sales into exclusivity fees per therapeutic sub-class, and royalties 4

6. FDA-registered; meets stringent standards for primary drug containers

7. Designed for growth, with 400MM annual syringe capacity (stage one)

8. Offers customers a broad spectrum of services at one location

9. Automated assembly systems used to attain optimal quality5

10. 6 Safety devices mandated in U.S. healthcare facilities to protect those at risk of needlestick injury; E.U. facilities now following Reported needlestick injuries largely stable, despite enforcement Needlestick Injuries Caused by Syringes Among Hospital Workers in Massachusetts Sharps Injuries among Hospital Workers in Massachusetts 2002 - 2009. Massachusetts Sharps Injury Surveillance System Mandatory Use of Safety Devices in Healthcare

12. Passive activation of needle retraction mechanism

13. Optimal needlestick protection

14. Operator controlled withdrawal

15. Directly from body into barrel

16. No risk of aerosol (splatter)

17. Non-reusable / tamper-proof

18. Intuitive use, convenient disposal7

20. 2.4B prefilled syringes in 2010, 12% annual growth rate* Prefilled Syringes 2010 Greystone Associates

21. Pharmaceutical Market for Prefilled Syringes 9 Selection of Marketed Prefilled Drugs by Therapeutic Class and Company Number of Prefilled Drugs

22. Unifill Standard prefilled syringe (left) next to three attached with an ancillary safety product Market Transitionto Prefilled Safety Syringes 10

24. Now in production

25. Controlled retraction into barrel

26. Needle locked after use for convenient, compact disposalUnifill – The Leading Edge of Our Portfolio

28. Designed for integration into standard fill-finish lines

29. USP-compliant materials in the drug fluid path

30. Eliminates use of ancillary safety, minimal packaging volumes

31. Uniqueness makes it ideal for brand differentiation12

33. Intense competition between branded, generic and biosimilar drugs within many fast-growing therapeutic classes

34. Innovative devices with superior, value-adding features can:

35. Deliver powerful brand differentiation in competitive areas

36. Optimize (or extend) product drug and build market share

37. Generate unique claims that can obstruct genericsDevice-Led Brand Differentiation for Drugs

38. 14 Sanofi paid $40MM for access rights to Unifill in classes of anti-thrombotic agents and vaccines until June 2014 Discussions now accelerating with multiple additional parties Potential revenue generating opportunities for Unifill syringe include commercial sales, access fees and royalties Unifill: A challenge most thought impossible

39. Production Underway, Initial Sales Imminent 15 Initial sales to commence in July this year to multiple customers Initial sales this year at relatively low volumes with high prices Expected full optimization of 60MM unit line during 2012

41. Require injection into patient (liquid form or reconstitution)

42. Pharmaceutical companies seeking devices that can be customized to specific needs of the drug and target patient^ Pfizer, EvaluatePharma

43. 17 Patient Self-Administration of Injectable Drugs Patient self-injection desirable Reduced healthcare costs Convenient to patient during use, portability and disposal Adherence to self-treatment Preference for prescribing Device segments targeted at patient self-administration (right) Market Trends Favoring Unilife’s Expansion

44. Unilife earned a reputation for device innovation via Unifill syringe Unifill platform now expanding into multiple product variants PharmaceuticalleadersapproachingUnilifewithotherunmetneeds Drug-specific collaborations from R&D thru to commercial sales Multiple projects with multiple partners in multiple device areas 18 Customer-Driven Technology Pipeline

46. Customized to meet specific needs of biologics and target patient

47. Unilife is an emerging leader for advanced drug delivery devices

48. Fully aligned to serve customer needs with speed and innovation

49. Unifill: the first and only prefill syringes with integrated safety

50. Significant commercial potential for broad array of injectable drugs

51. Arich, fast expanding portfolio being driven by customer need