This presentation talks about the cell cycle and mitosis. Also, an integration of cancer cells will be tackled in this presentation in accordance to uncontrolled cell division or mitosis.

1. Cell Reproduction:
Mitosis
Prepared by: Mr. Russel F. Deleña
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2. Cell Reproduction: Mitosis
Suppose you are having a cupcake business and
one time your stock runs low having 24 pieces of
cupcakes left. There is a customer that orders 3
dozens of cupcakes, how will you attend to your
problem of having low number of cupcakes?
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3. Cell Reproduction: Mitosis
THE CELL
CYCLE
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4. Cell Reproduction: Mitosis
• The cell initially grows.
• Preparation for the next stage of the cell cycle.
• Characterized by protein and ribonucleic acid
(RNA) synthesis.
G1
S
• The period of DNA synthesis or replication.
• The chromosomes are duplicated in preparation
for the next cell division 4

5. Cell Reproduction: Mitosis
• Represents a period of rapid cell growth to
prepare for cell division.
• Two centrosomes appear in the cytoplasm.
G2
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MITOSIS
MEIOSIS

6. Cell Reproduction: Mitosis
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Pro-
phase
Prome-
taphase
Meta-
phase
Ana-
phase
Telo-
phase
and
Cytoki-
nesis

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• The nuclear membrane and
nucleoli may still be present.
• The chromosomes are thicker
and shorter because of repeated
coiling.
• At this stage, each chromosome
is made up of two identical
sister chromatids.
• The two chromatids produced
from one chromosome are still
attached at one point
PROPHASE

8. Cell Reproduction: Mitosis
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• The nuclear membrane has
disappeared while the highly
coiled chromosomes align at the
metaphase plate.
• Spindle fibers are also formed.
Each fiber binds to a protein
called the kinetochore at the
centromere of each sister
chromatid of the chromosome.
METAPHASE

9. Cell Reproduction: Mitosis
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• The paired centromeres of each
chromosome separate towards
the opposite poles of the cells
as they are pulled by the spindle
fibers through their
kinetochores.
ANAPHASE

10. Cell Reproduction: Mitosis
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• The chromosomes are now at
the opposite poles of the
spindle. They start to uncoil and
become indistinct under the
light microscope.
• A new nuclear membrane forms
around them while the spindle
fibers disappear.
TELOPHASE

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The BIG
question

12. Cell Reproduction: Mitosis
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CANCER

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CANCER• Uncontrolled cell division
due to DNA mutations
Mutations may be caused by:
1. radiation
2. smoking
3. Pollutants
4. chemicals
5. viruses

14. Cell Reproduction: Mitosis
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What does cancer
looks like??

15. Cell Reproduction: Mitosis
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What does cancer
looks like??

16. Cell Reproduction: Mitosis
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What does cancer
looks like??

17. Cell Reproduction: Mitosis
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Now, DO YOU WANT
to have CANCER?
Do you believe that healthy living
can prevent uncontrolled cell
division or cancer?

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3- Give concepts you learned today.
2- Give two ways in which you can use these
concepts in daily living
1- Question you want to ask

19. Cell Reproduction: Mitosis
The button are hyperlinks to
videos. If you wish to know what
are the videos, feel free to
message me at my FB account
(Russel Flores Deleña) so that I
can send you the link for the
videos used in this presentation.
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