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Ted Farrar, MD
Fellowship Director, Primary Care Sports Medicine
            USF-MPM FM Residency
Disclosure

 Neither I nor any family member have any
  relevant financial relationships to be discussed,
 directly or indirectly, referred to or illustrated
 with or without recognition within this
 presentation.
Goals
 Concussion Testing & Examination
   History & Physical
   Neurocognitive Testing
 Treatment
   Pharmacologic
   Non-Pharmacologic
Concussion Evaluation
 Symptom History
    Includes PMH (Migraines, ADHD, etc.)
 Physical Exam
   Neurologic
 Neurocognitive Testing
   Adjunctive Tool
Symptom History
 Onset & Duration
 Quality & Intensity
 Should Resolve Prior to RTP
 Some Predictive Value
    Dizziness
    Headache
    Fogginess
Physical Exam
 Nystagmus
 Saccades
 Gaze Stability
 Balance Testing
 Neurocognitive Testing
Neurocognitive Testing
 ImPACT
   www.impacttest.com
 Headminder
   www.cogstate.com/go/sport
 Cogstate
   www.headminder.com
 Concussion Vital Signs
   www.concussionvitalsigns.com
Neurocognitive Testing
 Identify Occult Cognitive Impairment
 Attention to Several Domains
   Attention & Memory
   Cognitive Processing Speed
   Reaction Time
 Moderate Sensitivity
  79%, PPV 90%, NPV 82%
Neurocognitive Testing
 Results Can Assist
   Severity
   Prognosis
   Status of the Recovery
   Guide Treatment Considerations
   Helps Educate
Recommendations For Use
 Baseline Testing
 High-Risk Athletes with History
 Athletes who Deny Symptoms
 Assist in Accelerated Return
 Medicolegal Support
ImPACT Test: 6 Phases
Word Discrimination: 12 Word Recall


Design Memory: 12 Random Patterns
X’s & O’s: Match the Pattern / Speed Test
Symbol Matching Test: 27 Times
Color Match: Squares, then Boxes
3 Letter Memory / Reverse Countdown
Repeat Phase 1 & 2
Neurocognitive Testing
 Not all Cases Require Testing
 Adjunctive Tool
   Symptoms
   Physical Exam
 NOT Sole Determinant w/ RTP
Additional Tools
 Imaging
    CT
    DTI
    fMRI
 Biochemical Markers
Treatments
 Directed to Symptom Cluster(s)

  Neuropsyche        Cognitive


    Migraine /         Sleep
     Physical       Disturbance
Symptom Domains
 Neuropsychiatric       Cognitive

 More emotional     Attention Problems
 Sadness            Memory
 Nervousness        Fogginess & Fatigue
 Irritability       Executive Slowing
Symptom Domains
     Migraine /               Sleep
      Physical             Disturbance

 Headaches             Falling Asleep
 Visual & Dizziness    Sleeping less
 Phono/Photophobia
 Nausea
Pharmacologic Treatments
 Symptom Clusters
   Amantadine, et al   Cognitive Set        Sleep & / or Mood
                        “Foggy”              Falling asleep
   Melatonin           Memory               Staying asleep
                        Concentration        Anxious
   prn Imitrex         Fatigue              Irritability

   Tylenol
 No FDA indications                Somatic Set
                                    Headache
                                    Dizzy / Nausea
                                    Light / Sound
Cognitive Medications
 Amantadine
   Dopaminergic / noradrenergic
   Improves Symptoms & Scores
 Ritalin
   Processing speed & General Function
   Improved Recovery Rate
Non-Pharmacologic
 Academic / School Accommodations
 Athletic Accommodations
 Rehabilitative Needs
   Vestibular Therapy
   Ocular Therapy
Return to Activity
 Symptom Free
 No Medication or Rehab
 At Baseline
 RTP Protocol
   Florida State Law
Graded RTP Protocol from 3rd ICCS
   Consensus Statement, Zurich 2008
Rehab Stage                      Fx Exercise at Each Rehab Stage       Objective of Each Stage

1. No activity                   Complete rest (physical and           Recovery
                                 cognitive)
2. Light aerobic exercise        Walk, swim or stationary bike         Increase HR
                                 keeping intensity < 70% MPHR;
                                 no resistance training
3. Sport-specific exercise       Sport-specific drills with no head    Add movement
                                 impact activities
4. Non-contact training drills   Progression to more complex drills;   Exercise, coordination and
                                 may start progressive resistance      cognitive load
                                 training
5. Full contact practice         After medical clearance;              Restore confidence and assess
                                 participate in normal activities      functional skills by coaching staff
6. RTP                           Normal game play
References
   Iverson G. Predicting slow recovery from sports-related concussion: the new simple-complex distinction. Clinical Journal of Sport Medicine.
    2007: 17(1), 1731-Pardini D, Stump J, Lovell MR, Collins MW, Moritz K, Fu F. The post-concussion symptoms scale (PCSS): A factor analysis.
    British Journal of Sports Medicine, 2004: 38, 661.
   Collins MW, Iverson GL, Lovell MR, McKeag DB, Norwig J, Maroon J. On-field predictors of neuropsychological and symptom deficit
    following sports-related concussion. Clinical Journal of Sport Medicine, 2003: 13(4), 222-229.
    Lau BC, Lovell MR, Collins MW, Pardini JE. Neurocognitive and symptom predictors of recovery in high school athletes. Clinical Journal of
    Sports Medicine, 2009: 19(3), 216-221.
   Peer reviewed Practice parameter: the management of concussion in sports (summary statement). Report of the Quality Standards
    Subcommittee. Neurology 1997 Mar;48(3):581-5.
   Lovell MR, Collins MW, Iverson GL, Johnston KM, Bradley JP. Grade 1 or "ding" concussions in high school athletes. Am J Sports Med 2004
    Jan-Feb;32(1):47-54.
   Aubry M, Cantu R, Dvorak J, Graf-Baumann T, Johnston K, Kelly J, Lovell M, McCrory P, Meeuwisse W, Schamasch P; Concussion in Sport
    Group. Summary and agreement statement of the First International Conference on Concussion in Sport, Vienna 2001. Recommendations
    for the improvement of safety and health of athletes who may suffer concussive injuries. Br J Sports Med 2002 Feb;36(1):6-10.
   McCrory P, Johnston K, Meeuwisse W, Aubry M, Cantu R, Dvorak J, Graf-Baumann T, Kelly J, Lovell M, Schamasch P; International
    Symposium on Concussion in Sport. Summary and agreement statement of the 2nd International Conference on Concussion in Sport,
    Prague 2004. Clin J Sport Med 2005 Mar;15(2):48-55.
   Concussion (mild traumatic brain injury) and the team physician: a consensus statement. Med Sci Sports Exerc 2006 Feb;38(2):395-9.
   McCrory P, Meeuwisse W, Johnston K, Dvorak J, Aubry M, Molloy M, Cantu R. Consensus Statement on Concussion in Sport: the 3rd
    International Conference on Concussion in Sport held in Zurich, November 2008. Br J Sports Med 2009 May;43 Suppl 1:i76-90.
   AAN Position Statement on Sports Concussion October 2010 available at http://www.aan.com/globals/axon/assets/7913.pdf
   Guskiewicz KM, Marshall SW, Bailes J, McCrea M, Harding HP Jr, Matthews A, Mihalik JR, Cantu RC. Recurrent concussion and risk of
    depression in retired professional football players. Med Sci Sports Exerc 2007 Jun;39(6):903-09.
   McKee AC, Cantu RC, et al. Chronic Traumatic Encephalopathy in Athletes: Progressive Tauopathy following Repetitive Head Injury. J
    Neuropathol Exp Neurol 2009 July; 68(7): 709–735..
   Neal MT, Wilson JL, Hsu W, Powers AK. Concussions: What a neurosurgeon should kow about current scientific evidence and management
    strategies. Surg Neurol Int 2012;3:1`6
   Johnson EW, Kegel NE, Collins MW. Neuropsychological Assessment of Sport-Related Concussion. Clin Sports Med 2011:30, 73-88
   Reference Bibliography not otherwise specifically mentioned as of November 2011:
    http://impacttest.com/uploads/resources/Updated_References11_11.pdf

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Concussion Testing & Treatment

  • 1. Ted Farrar, MD Fellowship Director, Primary Care Sports Medicine USF-MPM FM Residency
  • 2. Disclosure  Neither I nor any family member have any relevant financial relationships to be discussed, directly or indirectly, referred to or illustrated with or without recognition within this presentation.
  • 3. Goals  Concussion Testing & Examination  History & Physical  Neurocognitive Testing  Treatment  Pharmacologic  Non-Pharmacologic
  • 4. Concussion Evaluation  Symptom History  Includes PMH (Migraines, ADHD, etc.)  Physical Exam  Neurologic  Neurocognitive Testing  Adjunctive Tool
  • 5. Symptom History  Onset & Duration  Quality & Intensity  Should Resolve Prior to RTP  Some Predictive Value  Dizziness  Headache  Fogginess
  • 6. Physical Exam  Nystagmus  Saccades  Gaze Stability  Balance Testing  Neurocognitive Testing
  • 7. Neurocognitive Testing  ImPACT  www.impacttest.com  Headminder  www.cogstate.com/go/sport  Cogstate  www.headminder.com  Concussion Vital Signs  www.concussionvitalsigns.com
  • 8. Neurocognitive Testing  Identify Occult Cognitive Impairment  Attention to Several Domains  Attention & Memory  Cognitive Processing Speed  Reaction Time  Moderate Sensitivity  79%, PPV 90%, NPV 82%
  • 9. Neurocognitive Testing  Results Can Assist  Severity  Prognosis  Status of the Recovery  Guide Treatment Considerations  Helps Educate
  • 10. Recommendations For Use  Baseline Testing  High-Risk Athletes with History  Athletes who Deny Symptoms  Assist in Accelerated Return  Medicolegal Support
  • 11. ImPACT Test: 6 Phases Word Discrimination: 12 Word Recall Design Memory: 12 Random Patterns
  • 12. X’s & O’s: Match the Pattern / Speed Test
  • 14. Color Match: Squares, then Boxes
  • 15. 3 Letter Memory / Reverse Countdown Repeat Phase 1 & 2
  • 16. Neurocognitive Testing  Not all Cases Require Testing  Adjunctive Tool  Symptoms  Physical Exam  NOT Sole Determinant w/ RTP
  • 17. Additional Tools  Imaging  CT  DTI  fMRI  Biochemical Markers
  • 18. Treatments  Directed to Symptom Cluster(s) Neuropsyche Cognitive Migraine / Sleep Physical Disturbance
  • 19. Symptom Domains Neuropsychiatric Cognitive  More emotional  Attention Problems  Sadness  Memory  Nervousness  Fogginess & Fatigue  Irritability  Executive Slowing
  • 20. Symptom Domains Migraine / Sleep Physical Disturbance  Headaches  Falling Asleep  Visual & Dizziness  Sleeping less  Phono/Photophobia  Nausea
  • 21. Pharmacologic Treatments  Symptom Clusters  Amantadine, et al Cognitive Set Sleep & / or Mood “Foggy” Falling asleep  Melatonin Memory Staying asleep Concentration Anxious  prn Imitrex Fatigue Irritability  Tylenol  No FDA indications Somatic Set Headache Dizzy / Nausea Light / Sound
  • 22. Cognitive Medications  Amantadine  Dopaminergic / noradrenergic  Improves Symptoms & Scores  Ritalin  Processing speed & General Function  Improved Recovery Rate
  • 23. Non-Pharmacologic  Academic / School Accommodations  Athletic Accommodations  Rehabilitative Needs  Vestibular Therapy  Ocular Therapy
  • 24. Return to Activity  Symptom Free  No Medication or Rehab  At Baseline  RTP Protocol  Florida State Law
  • 25. Graded RTP Protocol from 3rd ICCS Consensus Statement, Zurich 2008 Rehab Stage Fx Exercise at Each Rehab Stage Objective of Each Stage 1. No activity Complete rest (physical and Recovery cognitive) 2. Light aerobic exercise Walk, swim or stationary bike Increase HR keeping intensity < 70% MPHR; no resistance training 3. Sport-specific exercise Sport-specific drills with no head Add movement impact activities 4. Non-contact training drills Progression to more complex drills; Exercise, coordination and may start progressive resistance cognitive load training 5. Full contact practice After medical clearance; Restore confidence and assess participate in normal activities functional skills by coaching staff 6. RTP Normal game play
  • 26.
  • 27. References  Iverson G. Predicting slow recovery from sports-related concussion: the new simple-complex distinction. Clinical Journal of Sport Medicine. 2007: 17(1), 1731-Pardini D, Stump J, Lovell MR, Collins MW, Moritz K, Fu F. The post-concussion symptoms scale (PCSS): A factor analysis. British Journal of Sports Medicine, 2004: 38, 661.  Collins MW, Iverson GL, Lovell MR, McKeag DB, Norwig J, Maroon J. On-field predictors of neuropsychological and symptom deficit following sports-related concussion. Clinical Journal of Sport Medicine, 2003: 13(4), 222-229.  Lau BC, Lovell MR, Collins MW, Pardini JE. Neurocognitive and symptom predictors of recovery in high school athletes. Clinical Journal of Sports Medicine, 2009: 19(3), 216-221.  Peer reviewed Practice parameter: the management of concussion in sports (summary statement). Report of the Quality Standards Subcommittee. Neurology 1997 Mar;48(3):581-5.  Lovell MR, Collins MW, Iverson GL, Johnston KM, Bradley JP. Grade 1 or "ding" concussions in high school athletes. Am J Sports Med 2004 Jan-Feb;32(1):47-54.  Aubry M, Cantu R, Dvorak J, Graf-Baumann T, Johnston K, Kelly J, Lovell M, McCrory P, Meeuwisse W, Schamasch P; Concussion in Sport Group. Summary and agreement statement of the First International Conference on Concussion in Sport, Vienna 2001. Recommendations for the improvement of safety and health of athletes who may suffer concussive injuries. Br J Sports Med 2002 Feb;36(1):6-10.  McCrory P, Johnston K, Meeuwisse W, Aubry M, Cantu R, Dvorak J, Graf-Baumann T, Kelly J, Lovell M, Schamasch P; International Symposium on Concussion in Sport. Summary and agreement statement of the 2nd International Conference on Concussion in Sport, Prague 2004. Clin J Sport Med 2005 Mar;15(2):48-55.  Concussion (mild traumatic brain injury) and the team physician: a consensus statement. Med Sci Sports Exerc 2006 Feb;38(2):395-9.  McCrory P, Meeuwisse W, Johnston K, Dvorak J, Aubry M, Molloy M, Cantu R. Consensus Statement on Concussion in Sport: the 3rd International Conference on Concussion in Sport held in Zurich, November 2008. Br J Sports Med 2009 May;43 Suppl 1:i76-90.  AAN Position Statement on Sports Concussion October 2010 available at http://www.aan.com/globals/axon/assets/7913.pdf  Guskiewicz KM, Marshall SW, Bailes J, McCrea M, Harding HP Jr, Matthews A, Mihalik JR, Cantu RC. Recurrent concussion and risk of depression in retired professional football players. Med Sci Sports Exerc 2007 Jun;39(6):903-09.  McKee AC, Cantu RC, et al. Chronic Traumatic Encephalopathy in Athletes: Progressive Tauopathy following Repetitive Head Injury. J Neuropathol Exp Neurol 2009 July; 68(7): 709–735..  Neal MT, Wilson JL, Hsu W, Powers AK. Concussions: What a neurosurgeon should kow about current scientific evidence and management strategies. Surg Neurol Int 2012;3:1`6  Johnson EW, Kegel NE, Collins MW. Neuropsychological Assessment of Sport-Related Concussion. Clin Sports Med 2011:30, 73-88  Reference Bibliography not otherwise specifically mentioned as of November 2011: http://impacttest.com/uploads/resources/Updated_References11_11.pdf