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Geographical Variations among Age-Adjusted
             Low-Risk Primary
 Cesarean Section (CS) Rates in California




               Nikki Stoddart
                 Masters Candidate
              Division of Epidemiology
      Department of Health Research and Policy
       Stanford University, School of Medicine



              : Transforming Maternity Care
A Brief History of Cesarean Birth




           The Birth of Asclepius
            1549 Alessandro Beneditti
                “De Re Medica”



          : Transforming Maternity Care
Origins of Cesarean Birth
   Historical record indicates infants born via
    Cesarean
     GreekMythology: Apollo removed Asclepius
     from Coronis’ abdomen
     Procedure performed on living women in
     Ancient China




                 : Transforming Maternity Care
Suetonius 1506 Woodcut
Lives of the Twelve Caesares

  : Transforming Maternity Care
Why is it Called “Caesarean”?
   Named for the birth of Julius Caesar?
     Unlikely because in ancient Rome the
      procedure was done only when the mother
      was dead or dying but Caesar’s mother,
      Aurelia, lived to hear of his Conquest of
      Britain.




                 : Transforming Maternity Care
Oh, I see….
   Possibly from the Latin “caedare”,
    meaning “to cut”
     Roman    Law stated that women dying in
      childbirth must be cut open to remove the
      infant.
     Latin word “caesones” refers to children born
      by postmortem incision.


                  : Transforming Maternity Care
Finally, we have a live one!
   In 1500 Jacob Nufer, a Swiss pig gelder,
    performed a Cesarean on his ailing wife.
    She lived to be 77 years old, and birthed 5
    more children vaginally, including a set of
    twins.




                 : Transforming Maternity Care
But Still Gruesome….
   Between 1787- 1876, not a single Parisian
    woman survived the Cesarean operation.




                : Transforming Maternity Care
Performing Abdominal Surgery in Street Clothes
    Thomas Spencer Wells, Diseases of the Ovaries, 1872




             : Transforming Maternity Care
From Fatal to….....Less Fatal
   Maternal mortality rates dropped in the
    mid nineteenth century
       1846 William Morton- Diethyl Ether
           Women less likely to die from shock
       1860’s Josef Lister- Carbolic Acid
           Antiseptics and the germ theory




                       : Transforming Maternity Care
From Less Fatal…… To Safe
   C/S rates increase because:
     Post WWII, many new hospitals built
     Surgical technique improved
     Spinal Anesthesia developed
     Penicillin purified 1940
     Roman Catholic religious concerns




                 : Transforming Maternity Care
From Safe……to Every Day
   Continued rate increase far outpaces rise in birth rate
        Convenience
            Physicians can schedule around vacations, dinnertime
            Women can schedule time off from work
            Cutting loses (Better a section a 6pm than a delivery at 3 am)

     Culture
            “Too Posh to Push” – Victoria Beckam
            Vaginal Preservation Society

      C.Y.A.
            Malpractice suits
                  twins , breech, or VBACs are too risky




                                      : Transforming Maternity Care
   Technology in the Labor Suite Strongly Correlates with CS rates
      Labor induction
         r= 0.57 (P<.0001)

      Fetal monitoring
      Early Labor Admission
         “Failure to progress” leads to CS

              r= .62 (P <.0001)




                        : Transforming Maternity Care
   Financial
     Ob/gyn’s  must do more deliveries to pay MI
     C/S birth reimbursement is higher than
      vaginal




                 : Transforming Maternity Care
So, where does that leave us
    Today?
   WHO and USDHHS recommend no more
    than 15% of all births be C/S
     Beyond   15%, risks begin to eclipse benefits
   Yet 1/3 women in CA deliver via C/S




                   : Transforming Maternity Care
For every 5% decrease in the national
    primary CS rate there will be:
 Between 14-32 fewer maternal deaths
 33,000 fewer NICU admissions
 An savings of $750 million -$1.7 billion in
  healthcare costs.
                                                Plante 2006




                : Transforming Maternity Care
Risks of CS to Mother
   Blood Loss/Transfusion ≥ 1000 ml
   Postoperative Infections
   Subsequent Infertility
   Subsequent increased risk: placenta previa, placenta accreta, placental
    abruption and hemorrhage
   Injury to bowel, bladder, pelvic vasculature
   Rehospitalization
   Maternal Mortality
      RR: 1.6- 2.8




                          : Transforming Maternity Care
Risks of CS to Fetus
   Higher rates of respiratory distress
     5% C/S
     0.5% vaginal

 Possible iatrogenic prematurity
 Double risk of NICU admission
 Double risk of unexplained stillbirth in
  subsequent pregnancy

                 : Transforming Maternity Care
: Transforming Maternity Care
Objectives
   Identify regional variations of Age Adjusted Low-
    Risk C/S rates in California
     Simplify   regions: Northern, Southern CA and LA
      County
   Identify excess rates of C/S deliveries
    (Exclude Hospitals with less than 100 births per year)
   Inform hospital leaders; lead quality change



                      : Transforming Maternity Care
Low-Risk Primary Cesarean Section
                     Defined:

 Number of Cesarean Deliveries per 100 deliveries
among women who have not previously had a Cesarean
section (excludes abnormal presentation, preterm, fetal
death, multiple gestation, and breech procedures)
Primary C/S rates are age-adjusted.



                                  OSHPD Data 2006




                   : Transforming Maternity Care
Age-Adjusted Low-Risk Primary C/S
 Rates distributed to quintiles and
        applied to regions:

   0-20%; (Quintile 1: 5-13)
   20-40%; (Quintile 2: 14-15)
   40-60%; (Quintile 3: 16.1-16.9)
   60-80%; (Quintile 4: 17-19)
   80-100%;(Quintile 5: 19+)

                             Quintile ranges are per 100 births
           : Transforming Maternity Care
Top and Bottom two Quintiles (40%) of Age-adjusted
     Low-Risk Primary C/S Rates: Northern CA
   Hospitals with rates > 17                Hospitals with rates < 16
      n = 32/124 (25%)                          n=74/124 (60%)




                         : Transforming Maternity Care
Top and Bottom two Quintiles (40%) of Age-Adjusted
    Low-Risk Primary C/S Rates: LA County CA


Hospitals with rates >17                   Hospitals with rates < 16
   n=44/60 (73%)                               n=12/60 (20%)




                       : Transforming Maternity Care
Top and Bottom two Quintiles(40%) of Age-Adjusted
       Low Risk Primary C/S Rates: Southern CA

  Hospitals with rates >17                      Hospitals with rates < 16
     n=34/80 (43%)                                  n=40/80 (50%)




Hoag memorial


                Scripps La Jolla




                             : Transforming Maternity Care
Public Health Implications of Cesarean on Demand
Lauren Plante 2006




                              : Transforming Maternity Care
What are the total regional excess
cases above California’s mean primary
   C/S rate (16 per 100 live births)?




         : Transforming Maternity Care
Excess Cases of Low-risk
  Primary Cesarean Births (age-adjusted)
 above the State mean of 16 per 100 births.
                By Hospital
      San Francisco Bay Area 2006

    Total Excess C/S Cases= 349 (3%)
 Total low-risk non prior C/S= 11,043 (11%)
          Total Live Births= 97,000




                                        Good Samaritan
                                        San Jose




Hospitals with more than 200 Excess Cases are labeled
       : Transforming Maternity Care
Excess Cases of Low-risk
   Primary Cesarean Births (age-adjusted)
  above the State mean of 16 per 100 births.

        By Hospital, LA County 2006

    Total Excess C/S Cases= 4368 (20%)
  Total low-risk non-prior C/S= 22,327 (20%)
           Total Live Births= 114,846

               Valley Pres

Cedars Sinai            Hollywood Pres
                             Garfield    Citrus Memorial
      Huntington Park




    : Transforming Maternity Care
Excess Cases of Low-risk
     Primary Cesarean Births (age-adjusted)
      above the State mean of 16 per 100
                     births.
         By Hospital, Northern CA 2006

       Total Excess C/S Cases= 1312 (5%)
        Total Non-Prior C/S= 23,745 (11%)
             Total Live Births= 212,919




                 Good Samaritan San Jose




      : Transforming Maternity Care
Hospitals with more than 200 Excess Cases are labeled
Birth Costs (In thousands)
20000
18000
16000
14000
12000
10000                                                    Vaginal Birth
 8000                                                    Cesarean Birth
 6000
 4000
 2000
    0
        Physician Cost    Hospital Cost   Total Cost


                         : Transforming Maternity Care
Financial Implications of California’s
      Excess Cases (Complications excluded)
   Total excess cases above state mean:
      17,677
   Excess Healthcare Costs per Annum:
      $ 93,422,945.00


   Total excess cases above 15 (WHO Recommendation):
      40,654
   Excess Healthcare Costs per Annum:
      $214,856,390.00




                           : Transforming Maternity Care
Conclusion:

   Next Steps?

   Questions/Comments?
     What benchmark should we use?
     Is Geomapping a useful tool for sharing data?



                  : Transforming Maternity Care

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Nikkipowerpoint For Epi

  • 1. Geographical Variations among Age-Adjusted Low-Risk Primary Cesarean Section (CS) Rates in California Nikki Stoddart Masters Candidate Division of Epidemiology Department of Health Research and Policy Stanford University, School of Medicine : Transforming Maternity Care
  • 2. A Brief History of Cesarean Birth The Birth of Asclepius 1549 Alessandro Beneditti “De Re Medica” : Transforming Maternity Care
  • 3. Origins of Cesarean Birth  Historical record indicates infants born via Cesarean  GreekMythology: Apollo removed Asclepius from Coronis’ abdomen  Procedure performed on living women in Ancient China : Transforming Maternity Care
  • 4. Suetonius 1506 Woodcut Lives of the Twelve Caesares : Transforming Maternity Care
  • 5. Why is it Called “Caesarean”?  Named for the birth of Julius Caesar?  Unlikely because in ancient Rome the procedure was done only when the mother was dead or dying but Caesar’s mother, Aurelia, lived to hear of his Conquest of Britain. : Transforming Maternity Care
  • 6. Oh, I see….  Possibly from the Latin “caedare”, meaning “to cut”  Roman Law stated that women dying in childbirth must be cut open to remove the infant.  Latin word “caesones” refers to children born by postmortem incision. : Transforming Maternity Care
  • 7. Finally, we have a live one!  In 1500 Jacob Nufer, a Swiss pig gelder, performed a Cesarean on his ailing wife. She lived to be 77 years old, and birthed 5 more children vaginally, including a set of twins. : Transforming Maternity Care
  • 8. But Still Gruesome….  Between 1787- 1876, not a single Parisian woman survived the Cesarean operation. : Transforming Maternity Care
  • 9. Performing Abdominal Surgery in Street Clothes Thomas Spencer Wells, Diseases of the Ovaries, 1872 : Transforming Maternity Care
  • 10. From Fatal to….....Less Fatal  Maternal mortality rates dropped in the mid nineteenth century  1846 William Morton- Diethyl Ether  Women less likely to die from shock  1860’s Josef Lister- Carbolic Acid  Antiseptics and the germ theory : Transforming Maternity Care
  • 11. From Less Fatal…… To Safe  C/S rates increase because:  Post WWII, many new hospitals built  Surgical technique improved  Spinal Anesthesia developed  Penicillin purified 1940  Roman Catholic religious concerns : Transforming Maternity Care
  • 12. From Safe……to Every Day  Continued rate increase far outpaces rise in birth rate  Convenience  Physicians can schedule around vacations, dinnertime  Women can schedule time off from work  Cutting loses (Better a section a 6pm than a delivery at 3 am) Culture  “Too Posh to Push” – Victoria Beckam  Vaginal Preservation Society  C.Y.A.  Malpractice suits  twins , breech, or VBACs are too risky : Transforming Maternity Care
  • 13. Technology in the Labor Suite Strongly Correlates with CS rates  Labor induction  r= 0.57 (P<.0001)  Fetal monitoring  Early Labor Admission  “Failure to progress” leads to CS  r= .62 (P <.0001) : Transforming Maternity Care
  • 14. Financial  Ob/gyn’s must do more deliveries to pay MI  C/S birth reimbursement is higher than vaginal : Transforming Maternity Care
  • 15. So, where does that leave us Today?  WHO and USDHHS recommend no more than 15% of all births be C/S  Beyond 15%, risks begin to eclipse benefits  Yet 1/3 women in CA deliver via C/S : Transforming Maternity Care
  • 16. For every 5% decrease in the national primary CS rate there will be:  Between 14-32 fewer maternal deaths  33,000 fewer NICU admissions  An savings of $750 million -$1.7 billion in healthcare costs. Plante 2006 : Transforming Maternity Care
  • 17. Risks of CS to Mother  Blood Loss/Transfusion ≥ 1000 ml  Postoperative Infections  Subsequent Infertility  Subsequent increased risk: placenta previa, placenta accreta, placental abruption and hemorrhage  Injury to bowel, bladder, pelvic vasculature  Rehospitalization  Maternal Mortality  RR: 1.6- 2.8 : Transforming Maternity Care
  • 18. Risks of CS to Fetus  Higher rates of respiratory distress  5% C/S  0.5% vaginal  Possible iatrogenic prematurity  Double risk of NICU admission  Double risk of unexplained stillbirth in subsequent pregnancy : Transforming Maternity Care
  • 20. Objectives  Identify regional variations of Age Adjusted Low- Risk C/S rates in California  Simplify regions: Northern, Southern CA and LA County  Identify excess rates of C/S deliveries (Exclude Hospitals with less than 100 births per year)  Inform hospital leaders; lead quality change : Transforming Maternity Care
  • 21. Low-Risk Primary Cesarean Section Defined:  Number of Cesarean Deliveries per 100 deliveries among women who have not previously had a Cesarean section (excludes abnormal presentation, preterm, fetal death, multiple gestation, and breech procedures) Primary C/S rates are age-adjusted. OSHPD Data 2006 : Transforming Maternity Care
  • 22. Age-Adjusted Low-Risk Primary C/S Rates distributed to quintiles and applied to regions:  0-20%; (Quintile 1: 5-13)  20-40%; (Quintile 2: 14-15)  40-60%; (Quintile 3: 16.1-16.9)  60-80%; (Quintile 4: 17-19)  80-100%;(Quintile 5: 19+) Quintile ranges are per 100 births : Transforming Maternity Care
  • 23. Top and Bottom two Quintiles (40%) of Age-adjusted Low-Risk Primary C/S Rates: Northern CA Hospitals with rates > 17 Hospitals with rates < 16 n = 32/124 (25%) n=74/124 (60%) : Transforming Maternity Care
  • 24. Top and Bottom two Quintiles (40%) of Age-Adjusted Low-Risk Primary C/S Rates: LA County CA Hospitals with rates >17 Hospitals with rates < 16 n=44/60 (73%) n=12/60 (20%) : Transforming Maternity Care
  • 25. Top and Bottom two Quintiles(40%) of Age-Adjusted Low Risk Primary C/S Rates: Southern CA Hospitals with rates >17 Hospitals with rates < 16 n=34/80 (43%) n=40/80 (50%) Hoag memorial Scripps La Jolla : Transforming Maternity Care
  • 26. Public Health Implications of Cesarean on Demand Lauren Plante 2006 : Transforming Maternity Care
  • 27. What are the total regional excess cases above California’s mean primary C/S rate (16 per 100 live births)? : Transforming Maternity Care
  • 28. Excess Cases of Low-risk Primary Cesarean Births (age-adjusted) above the State mean of 16 per 100 births. By Hospital San Francisco Bay Area 2006 Total Excess C/S Cases= 349 (3%) Total low-risk non prior C/S= 11,043 (11%) Total Live Births= 97,000 Good Samaritan San Jose Hospitals with more than 200 Excess Cases are labeled : Transforming Maternity Care
  • 29. Excess Cases of Low-risk Primary Cesarean Births (age-adjusted) above the State mean of 16 per 100 births. By Hospital, LA County 2006 Total Excess C/S Cases= 4368 (20%) Total low-risk non-prior C/S= 22,327 (20%) Total Live Births= 114,846 Valley Pres Cedars Sinai Hollywood Pres Garfield Citrus Memorial Huntington Park : Transforming Maternity Care
  • 30. Excess Cases of Low-risk Primary Cesarean Births (age-adjusted) above the State mean of 16 per 100 births. By Hospital, Northern CA 2006 Total Excess C/S Cases= 1312 (5%) Total Non-Prior C/S= 23,745 (11%) Total Live Births= 212,919 Good Samaritan San Jose : Transforming Maternity Care Hospitals with more than 200 Excess Cases are labeled
  • 31. Birth Costs (In thousands) 20000 18000 16000 14000 12000 10000 Vaginal Birth 8000 Cesarean Birth 6000 4000 2000 0 Physician Cost Hospital Cost Total Cost : Transforming Maternity Care
  • 32. Financial Implications of California’s Excess Cases (Complications excluded)  Total excess cases above state mean:  17,677  Excess Healthcare Costs per Annum:  $ 93,422,945.00  Total excess cases above 15 (WHO Recommendation):  40,654  Excess Healthcare Costs per Annum:  $214,856,390.00 : Transforming Maternity Care
  • 33. Conclusion:  Next Steps?  Questions/Comments?  What benchmark should we use?  Is Geomapping a useful tool for sharing data? : Transforming Maternity Care

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