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Treatment of Epilepsy in ER Submitted to  AskTheNeurologist.Com   in 2007 Author Anon.
The first seizure ,[object Object],[object Object],[object Object],[object Object],[object Object]
Seizure recurrence ,[object Object],[object Object],[object Object],[object Object]
Risk factors for seizure recurrence ,[object Object],[object Object],[object Object],[object Object]
Treatment of status epilepticus ,[object Object],[object Object],[object Object],[object Object]
Definitions ,[object Object],[object Object]
Operational definition ,[object Object]
Predictors of outcome ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Outcomes ,[object Object],[object Object],[object Object],[object Object],[object Object]
Assessment and supportive measures ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Glucose ,[object Object],[object Object],[object Object]
Blood pressure ,[object Object],[object Object],[object Object],[object Object]
Body temperature ,[object Object],[object Object]
Systemic treatment ,[object Object],[object Object],[object Object],[object Object]
1 st  line drug treatments ,[object Object],[object Object],[object Object],[object Object]
Benzodiazepines Can be used alone Necessitates use of a second long-acting drug Longer duration of action  Rapid redistribution into body fat  Less rapid penetration into brain  More rapid penetration into brain Less lipid soluble More lipid soluble Lorazepam Diazepam
Lorazepam ,[object Object]
Fosphenytoin ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Maximal brain concentrations of phenytoin ,[object Object],[object Object]
Phenobarbital ,[object Object],[object Object],[object Object]
IV Valproic acid ,[object Object],[object Object]
Refractory status epilepticus ,[object Object],[object Object],[object Object],[object Object],[object Object]
Recommend saline and dopamine infusion Myocardial depression Vasodilatation Decreased venous return Decreased cardiac perfusion Associated with profound systemic side effects Assessment clinical and on basis of EEG Potent Doses adjusted on basis of EEG responses Tachyphylaxis necessitates dose variation Pentobarbital Propofol  Midazolam
Recommendations regarding Barbiturates ,[object Object],[object Object]
Submitted to  AskTheNeurologist.Com   in 2007 Author Anon.

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ER treatment of Epilepsy

  • 1. Treatment of Epilepsy in ER Submitted to AskTheNeurologist.Com in 2007 Author Anon.
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  • 16. Benzodiazepines Can be used alone Necessitates use of a second long-acting drug Longer duration of action Rapid redistribution into body fat Less rapid penetration into brain More rapid penetration into brain Less lipid soluble More lipid soluble Lorazepam Diazepam
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  • 23. Recommend saline and dopamine infusion Myocardial depression Vasodilatation Decreased venous return Decreased cardiac perfusion Associated with profound systemic side effects Assessment clinical and on basis of EEG Potent Doses adjusted on basis of EEG responses Tachyphylaxis necessitates dose variation Pentobarbital Propofol Midazolam
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  • 25. Submitted to AskTheNeurologist.Com in 2007 Author Anon.