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The role of the Transcription Factor Engrailed in Neuronal Identity

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The role of the Transcription Factor Engrailed in Neuronal Identity Nelson Almodóvar Arbelo University of Puerto Rico at Cayey RISE Program student Bruno Marie-Bordes P.h.D. Institute of Neurobiology
What is a transcription factor? ,[object Object],[object Object]
Transcription Factors define the development of cells A B Transcription Factor x Transcription Factor y
Transcription Factors Regulate Aspects in the Neuronal Development ,[object Object],[object Object],[object Object],[object Object]
Engrailed during embryogenesis ,[object Object],[object Object]
Engrailed expression in the larva CNS ,[object Object],[object Object]
Hypothesis: Over-Expression of Engrailed will perturb neuronal development and/or maintenance.
Methods: Modifying gene expression in Drosophila using the Gal4/UAS system
Methods: Modifying gene expression in Drosophila using the Gal4/UAS system Early Neuroblasts UAS – Engrailed Post-Mitotic Motorneuron UAS – Engrailed
Objectives ,[object Object],[object Object]
Objectives ,[object Object]
References ,[object Object],[object Object]

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The role of the Transcription Factor Engrailed in Neuronal Identity

  • 1. The role of the Transcription Factor Engrailed in Neuronal Identity Nelson Almodóvar Arbelo University of Puerto Rico at Cayey RISE Program student Bruno Marie-Bordes P.h.D. Institute of Neurobiology
  • 2.
  • 3. Transcription Factors define the development of cells A B Transcription Factor x Transcription Factor y
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  • 7. Hypothesis: Over-Expression of Engrailed will perturb neuronal development and/or maintenance.
  • 8. Methods: Modifying gene expression in Drosophila using the Gal4/UAS system
  • 9. Methods: Modifying gene expression in Drosophila using the Gal4/UAS system Early Neuroblasts UAS – Engrailed Post-Mitotic Motorneuron UAS – Engrailed
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