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Antiseptic and disinfectant drugs
1. PHARMACOGNOSY
A seminar on
ANTISEPTIC AND DISINFECTANTS
Presented by ,
Mr. SHINDE N.G.
(M. Pharm.)
Satara college of pharmacy,
satara,MH,India.
2. ANTISEPTIC AND DISINFECTANTS
Antiseptics are the agent that sterilize the living surface.
while
Disinfectants kills bacteria and spores from nonliving surface.
Examples-
BENZOIN
MYRRH
NEEM
CURCUMA
4. BENZOIN
SYNONAME- Sumatra benzoin, gum benzoin, loban
BIOLOGICAL SOURCE- It is balsamic resin obtained from Styrax benzoin , Styrax
tonkinesis belongs to styraceae family.
GEOGRAPHICL DISTRIBUTION-
Produced from trees grown in south eastern
Asia- Sumatra, Indonesia.
COLLECTION-
benzoin is pathological resin collected
after 6 year from cultivated/wild trees
by incision near the base of tree.
The resinous material allow to solidified,
sundried
(yield-10kg/tree)
5. BENZOIN
CHEMICAL CONSTITUENTS-
Sumatra benzoin- free balsamic acids(benzoic and cinnamic acids).
also triterpenoid acids like suma-resinolic acid & siaresinolic acid
Slam benzoin- ester coniferyl benzoate(75%)
Styrol , vanillin, phenyl propyl cinnamate.
USES-
1. irritating expectorant
2. carminative
3. diuretic
4.Antiseptic
5.Protective
6. Treatment of URT infection (as inhalation)
.
7. MYRRH
SYNONAME- Myrrha, bol, gum myrrh
BIOLOGICAL SOURCE- It is oleo-gum-resin obtained from Commiphora molmol
belongs to Burseraceae family.
GEOGRAPHICL DISTRIBUTION-
found in north east africa and
southern arabia.
COLLECTION-
Burseraceae plants posses oleo-resinous
canals in their conducting tissue.
Plant is small shrub-3m height
By incision on bark it exudates yellowish
colored resin ,gradually hardens and
becomes reddish brown.
This mass is collected in goats
skin and sent to market.
8. MYRRH
CHEMICAL CONSTITUENTS-
10% thick VOLATILE OIL-
Terpenes, cuminic aldehyde, eugenol.
25-40% resins –
alpha, beta and gamma commiphoric acid
3-4% bitter principles
USES-
- stimulant,
- used as antiseptic,
- protective,
- used in mouthwashes.
ADULTRATION-
Arabian myrrh
Yamen myrrh
Indian bdellium(balsamoendron mukul)
9.
10. NEEM
SYNONAME- LIMB
BIOLOGICAL SOURCE- It consist of leaves and other aerial parts of Azadiracta indica
belongs to Meliaceae family.
GEOGRAPHICL DISTRIBUTION- it is indigenous and widely grown in India.
CULTIVATION- The plant is propagated by seeds. it survive at high
temp. little rainfall , nutrient deficient soil. The plant bears fruit
after 5 years.
CHEMICAL CONSTITUENTS-
Azadiractin, salanin, meliantriol
Leaves- nimbosterol, quercetin
Seeds- azadirtactin, salanin , meliantrol, meliacin
Bark- nimbin, nimbinin, nimbidin, nimbosterol, margosine.
USES- Antiseptic, insecticide, antiviral,treatement of AIDS
12. CURCUMA
SYNONAME- turmeric, haldi, Indian saffron
BIOLOGICAL SOURCE- It consist of dried or fresh rhizomes of Curcuma longa belongs to
Zinzibrraceae family.
GEOGRAPHICL DISTRIBUTION- it is cultivated in pak ., Malaysia, china.
india-MH, TN, WB, UP, PJ
CHEMICAL CONSTITUENTS-
5% VOLATILE OIL, RESIN, yellow coloring sub. Curcuminoids
Curcumin, turmerone, zingiberine, borneol, caprylic acid.
USES-
Antiseptic,
Expectorant,
In condiment
Coloring agent- ointment, creams
Antimicrobial
antiinflammatory