4. Others contributed to the discovery of DNA Rosalind Franklin: DNA image through X-ray technology Erwin Chargaff found that number of bases were approximately equal to their bonding partner A = T & C = G
18. Figure 11.8 Schematic representation of DNA Polymerase III Structure resembles a human right hand Template DNA thread through the palm; Thumb and fingers wrapped around the DNA
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21. Replication fork 3’ 5’ 3’ 5’ 5’ 3’ 3’ 5’ helicase SSB = single-stranded binding proteins primase DNA polymerase III DNA polymerase III DNA polymerase I ligase Okazaki fragments leading strand lagging strand SSB direction of replication
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24. DNA --> RNA --> Protein Proteins are the building blocks of the organism (traits)
25. Transcription - process where RNA is made from DNA Translation - process where proteins are made from RNA
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Editor's Notes
In 1953, Kornberg was appointed head of the Department of Microbiology in the Washington University School of Medicine in St. Louis. It was here that he isolated DNA polymerase I and showed that life (DNA) can be made in a test tube. In 1959, Kornberg shared the Nobel Prize for Physiology or Medicine with Severo Ochoa — Kornberg for the enzymatic synthesis of DNA, Ochoa for the enzymatic synthesis of RNA.
![Discovering the structure of DNA ,[object Object],[object Object],[object Object]](data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7)