1. There are two main types of ossification that form bone: intramembranous and endochondral. Endochondral ossification uses hyaline cartilage as a model and requires its breakdown before bone formation. 2. During postnatal growth of long bones, the epiphyseal plate contains zones of growth, transformation, and osteogenesis that allow elongation. Growth hormone and sex hormones regulate epiphyseal plate activity and closure during development. 3. Bone is constantly remodeled through the balanced actions of bone-forming osteoblasts and bone-resorbing osteoclasts. Hormonal and mechanical factors help control this remodeling process.