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World Anesthesia Drug Market , The

April 1, 2010

This Kalorama Information report - The World Anesthesia Drug Market - focuses on three
primary segments of anesthesia:

       General Anesthesia
       Local Anesthesia
       Adjunctive Therapies in Anesthesia

The report covers both currently marketed and late stage development anesthesia drugs in
detail. Revenues for each segment were generated using dollar and unit sales for each product.
Forecasted figures were generated using a combination of projected surgical procedures, patent
and exclusivity expirations, pricing trends, new developments and other factors.

The report includes statistical information for surgical procedures, incidence of conditions
requiring surgery, and other relevant information. Statistical information is presented as a
worldwide overview, with special emphasis on the U.S. The market segments provide an
overview, description of products on the market, description of products in development,
market estimates and forecasts, and competitive analysis of leading providers. The report
also includes current issues and trends affecting the industry.

The information for this report was gathered using both primary and secondary research
including comprehensive research of secondary sources such as company literature,
databases, investment reports, and medical and business journals. Telephone interviews and
email correspondence were the primary method of gathering information. For the purpose of this
study Kalorama Information conducted interviews with more than 50 key industry officials,
consultants, health care providers, and government personnel. These sources were the primary
basis in gathering information specifically relating to revenue and market share data presented
in this report. Specific interviews with pharmaceutical company representatives included
marketing directors, division managers, and product representatives.

All market data pertains to the world market at the manufacturers’ level. The base year for data
was 2009. Historical data was provided for the years 2007 and 2008, with forecast data
provided for 2010 through 2014. Compound annual growth rates (CAGRs) are provided for the
2007-2009, 2007-2014 and 2009-2014 periods for each industry segment covered. Competitive
analysis is provided for the year 2009 with a projected competitive analysis for 2014. The
forecasted market analysis for 2009-2014 was highly influenced by the probability of approval
and sales of products in late stage development, product marketing, and demographic trends.


Table of Contents

CHAPTER ONE: EXECUTIVE SUMMARY

       Introduction

       Scope and Methodology

       Size and Growth of the Market

       Issues and Trends Affecting Market

       Leading Competitors

CHAPTER TWO: INTRODUCTION: THE WORLD ANESTHESIA DRUG MARKET
     Introduction and History to Anesthesia Drugs

       Types of Anesthesia

       General Anesthesia

       Local Anesthesia

       Adjunctive Therapies in Anesthesia

       Routes of Administration

       Inhalation

       Mask Inhalation

       Laryngeal Mask

       Endotracheal Administration

       Controlled Respiration

       Intravenous

       Topical Application

       Transdermal/Transmucosal Application

       Distribution Channels

       Demographics and Statistics

       Worldwide Demographics

       Medical Procedures by Type
Complications in Anesthesia

CHAPTER THREE: GENERAL ANESTHESIA
     Overview

     Induction of General Anesthesia

     Preoxygenation

     Loss of Consciousness

     Description of Products

     Diprivan

     Ultane/Sevorane

     Lusedra

     Precedex

     Ethrane

     Forane

     Pentothal

     Suprane

     Ketalar

     Brevital

     Generic Drug Impact and Availability

     Research and Development

     Precedex

     CNS 7056

     AZD3043

     Market Size and Growth

     Total Market

     Market by Delivery Method

     Market by Geographical Region

     Competitive Analysis

CHAPTER FOUR: LOCAL ANESTHESIA
     Overview
Techniques of Administration

Topical Application

Transdermal/Transmucosal

Simple Local Infiltration

Regional Injections

Spinal and Epidural Anesthesia

Intrathecal Block

Epidural, Peridural Block

Description of Products

AminoAmides

Xylocaine/LidoSite/Lidoderm/Dentipatch

Zingo

Carbocaine/Isocaine/Polocaine

Marcaine/Sensorcaine

Citanest

Naropin

Septocaine

Amino Esters

Novocaine

Nesacaine

Cocaine Hydrochloride

Combinations

Synera/Pliaglis

EMLA

Generic Drug Impact and Availability

Research and Development

Market Size and Growth

Total Market

Market by Delivery Method
Market by Geographical Region

     Competitive Analysis

CHAPTER FIVE: ADJUNCTIVE THERAPIES IN ANESTHESIA
     Overview

     Description of Products

     Neuromuscular Blocking Agents

     Preanesthetic Sedation and Anesthesia Maintenance

     Anesthesia Reversal Agents

     Generic Drug Impact and Availability

     Research and Development

     Market Size and Growth

     Total Market

     Market by Geographical Region

     Competitive Analysis

CHAPTER SIX: ANESTHESIA DRUGS: TOTAL MARKET SIZE AND FORECAST
     Total Market Size and Forecast

     Anesthesia Market by Product Type

     Anesthesia Market by Geographical Region

     Competitor Analysis

CHAPTER SEVEN: ISSUES AND TRENDS AFFECTING THE ANESTHESIA DRUG MARKET
     Introduction

     Regulation of Anesthesia Drugs

     Dentistry and Anesthesia

     Anesthesia and Complications in Pediatric Applications

     Allergic Reactions in Anesthesia

     Recent Propofol Recall

     Anesthesia and the Benefits to Depression Patients

     Anesthesia and Sleep

     Gender Differences in Anesthesia Reaction

     Trends in Conscious Sedation
Long-term Effects of Anesthesia

CHAPTER EIGHT: CORPORATE PROFILES
     Introduction

      Abbott Laboratories

      AstraZeneca

      Baxter International

      Eisai Co

      Endo Pharmaceuticals Holdings, Inc

      Hospira, Inc

      Merck/Schering-Plough

      Roche

      List of Companies

LIST OF EXHIBITS

CHAPTER ONE: Executive Summary
     Table 1-1: The Total World Market for Anesthesia Drugs 2007-2014

      Figure 1-1: The Total Market for Anesthesia Drugs 2007-2014

CHAPTER TWO: Introduction The World Anesthesia Drug Market
     Table 2-1: World Population by Selected Geographical Region, 2010-2050

      Figure 2-1: World Population by Selected Geographical Region, 2010-2050

      Table 2-2: Procedures by Type, Average Annually 2006-2009

      Figure 2-2: Procedures by Type Worldwide, Average Annually 2006-2009

      Figure 2-3: Procedures by Type U.S., Average Annually 2006-2009

      Table 2-3: Worldwide Anesthesia Complications and Related Mortality

      Figure 2-4: Worldwide Anesthesia Complications and Related Mortality

CHAPTER THREE: General Anesthesia
     Table 3-1: Marketed Brands for General Anesthesia Drugs (Brand Name, Generic
     Name, and Manufacturer)

      Table 3-2: Selected Generic Drug Manufacturers and Products for General Anesthesia

      Table 3-1: Brand vs. Generic General Anesthetic Market 2007-2009

      Table 3-3: General Anesthesia Drugs in Development
Table 3-4: The Market for General Anesthesia Drugs 2007-2014

      Figure 3-2: The Market for General Anesthesia Drugs 2007-2014

      Table 3-5: The Market for General Anesthesia Drugs Estimated Products Sales by
      Delivery Method, 2009

      Figure 3-3: The Market for General Anesthesia Drugs Market Share by Delivery Method,
      2009

      Table 3-6: The Market for General Anesthesia Drugs Estimated Products Sales by
      Geographic Region, 2009

      Figure 3-4: The Market for General Anesthesia Drugs Market Share by Geographic
      Region, 2009

      Table 3-7: The Market for General Anesthesia Drugs Estimated Revenues and Market
      Share of Leading Suppliers 2007-2009

      Figure 3-5: The Market for General Anesthesia Drugs Estimated Market Share by
      Leading Suppliers 2009

CHAPTER FOUR: Local Anesthesia
     Table 4-1: Selected Marketed Local Anesthesia Drugs (Brand Name, Generic Name and
     Manufacturer)

      Table 4-2: Selected Generic Drug Manufacturers and Products for Local Anesthesia

      Table 4-1: Brand vs. Generic Local Anesthetic Market 2007-2009

      Table 4-3: Local Anesthesia Drugs in Development

      Table 4-4: The Market for Local Anesthesia Drugs 2004-2011

      Figure 4-2: The Total Market for Local Anesthesia Drugs 2004-2011

      Table 4-5: The Market for Local Anesthesia Drugs Estimated Products Sales by Delivery
      Method, 2009

      Figure 4-3: The Market for Local Anesthesia Drugs Market Share by Delivery Method,
      2009

      Table 4-6: The Market for Local Anesthesia Drugs Estimated Products Sales by
      Geographic Region, 2009

      Figure 4-4: The Market for Local Anesthesia Drugs Market Share by Geographic Region,
      2009

      Table 4-7: The Market for Local Anesthesia Drugs Estimated Revenues and Market
      Share of Leading Suppliers 2007-2009

      Figure 4-5: The Market for Local Anesthesia Drugs Estimated Market Share by Leading
      Suppliers 2009

CHAPTER FIVE: Adjunctive Therapies in Anesthesia
Table 5-1: Selected Marketed Adjunctive Therapies in Anesthesia (Type, Brand Name,
       Generic Name, and Manufacturer)

       Table 5-2: Selected Generic Drug Manufacturers and Products for Adjunctive Therapies
       in Anesthesia

       Table 5-1: Brand vs. Generic Adjunctive Therapies in Anesthesia Market 2007-2009

       Table 5-3: Adjunctive Therapies in Anesthesia in Development

       Table 5-4: The Market for Adjunctive Therapies in Anesthesia 2007-2014

       Figure 5-2: The Market for Adjunctive Therapies in Anesthesia 2007-2014

       Table 5-5: The Market for Adjunctive Therapies in Anesthesia Estimated Products Sales
       by Geographic Region, 2009

       Figure 5-3: The Market for Adjunctive Therapies in Anesthesia Market Share by
       Geographic Region, 2009

       Table 5-6: The Market for Adjunctive Therapies in Anesthesia Estimated Revenues and
       Market Share of Leading Suppliers 2009

       Figure 5-4: The Market for Adjunctive Therapies in Anesthesia Estimated Market Share
       by Leading Suppliers 2009

CHAPTER SIX: Anesthesia Drugs: Total Market Size and Forecast
     Table 6-1: The Total World Market for Anesthesia Drugs 2007-2014

       Figure 6-1: The Total Market for Anesthesia Drugs 2007-2014

       Table 6-2: Anesthesia Drug Market by Type 2007-2014

       Figure 6-2: Anesthesia Drug Market by Type 2007-2014

       Figure 6-3: Anesthesia Drug Market by Type 2009

       Figure 6-4: Anesthesia Drug Market by Type 2014

       Table 6-3: Anesthesia Drug Market Estimated Products Sales by Geographic Region,
       2009

       Figure 6-5: Anesthesia Drug Market Market Share by Geographic Region, 2009 125

       Table 6-4: Leading Suppliers Anesthesia Revenues and Significant Segments of
       Participation, 2009

       Figure 6-6: Leading Suppliers—Anesthesia Revenues, 2009

Available immediately for Online Download at
http://www.marketresearch.com/product/display.asp?productid=2614802
US: 800.298.5699

UK +44.207.256.3920

Int'l: +1.240.747.3093

Fax: 240.747.3004

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World Anesthesia Drug Market , The

  • 1. Get more info on this report! World Anesthesia Drug Market , The April 1, 2010 This Kalorama Information report - The World Anesthesia Drug Market - focuses on three primary segments of anesthesia: General Anesthesia Local Anesthesia Adjunctive Therapies in Anesthesia The report covers both currently marketed and late stage development anesthesia drugs in detail. Revenues for each segment were generated using dollar and unit sales for each product. Forecasted figures were generated using a combination of projected surgical procedures, patent and exclusivity expirations, pricing trends, new developments and other factors. The report includes statistical information for surgical procedures, incidence of conditions requiring surgery, and other relevant information. Statistical information is presented as a worldwide overview, with special emphasis on the U.S. The market segments provide an overview, description of products on the market, description of products in development, market estimates and forecasts, and competitive analysis of leading providers. The report also includes current issues and trends affecting the industry. The information for this report was gathered using both primary and secondary research including comprehensive research of secondary sources such as company literature, databases, investment reports, and medical and business journals. Telephone interviews and email correspondence were the primary method of gathering information. For the purpose of this study Kalorama Information conducted interviews with more than 50 key industry officials, consultants, health care providers, and government personnel. These sources were the primary basis in gathering information specifically relating to revenue and market share data presented in this report. Specific interviews with pharmaceutical company representatives included marketing directors, division managers, and product representatives. All market data pertains to the world market at the manufacturers’ level. The base year for data was 2009. Historical data was provided for the years 2007 and 2008, with forecast data provided for 2010 through 2014. Compound annual growth rates (CAGRs) are provided for the 2007-2009, 2007-2014 and 2009-2014 periods for each industry segment covered. Competitive analysis is provided for the year 2009 with a projected competitive analysis for 2014. The
  • 2. forecasted market analysis for 2009-2014 was highly influenced by the probability of approval and sales of products in late stage development, product marketing, and demographic trends. Table of Contents CHAPTER ONE: EXECUTIVE SUMMARY Introduction Scope and Methodology Size and Growth of the Market Issues and Trends Affecting Market Leading Competitors CHAPTER TWO: INTRODUCTION: THE WORLD ANESTHESIA DRUG MARKET Introduction and History to Anesthesia Drugs Types of Anesthesia General Anesthesia Local Anesthesia Adjunctive Therapies in Anesthesia Routes of Administration Inhalation Mask Inhalation Laryngeal Mask Endotracheal Administration Controlled Respiration Intravenous Topical Application Transdermal/Transmucosal Application Distribution Channels Demographics and Statistics Worldwide Demographics Medical Procedures by Type
  • 3. Complications in Anesthesia CHAPTER THREE: GENERAL ANESTHESIA Overview Induction of General Anesthesia Preoxygenation Loss of Consciousness Description of Products Diprivan Ultane/Sevorane Lusedra Precedex Ethrane Forane Pentothal Suprane Ketalar Brevital Generic Drug Impact and Availability Research and Development Precedex CNS 7056 AZD3043 Market Size and Growth Total Market Market by Delivery Method Market by Geographical Region Competitive Analysis CHAPTER FOUR: LOCAL ANESTHESIA Overview
  • 4. Techniques of Administration Topical Application Transdermal/Transmucosal Simple Local Infiltration Regional Injections Spinal and Epidural Anesthesia Intrathecal Block Epidural, Peridural Block Description of Products AminoAmides Xylocaine/LidoSite/Lidoderm/Dentipatch Zingo Carbocaine/Isocaine/Polocaine Marcaine/Sensorcaine Citanest Naropin Septocaine Amino Esters Novocaine Nesacaine Cocaine Hydrochloride Combinations Synera/Pliaglis EMLA Generic Drug Impact and Availability Research and Development Market Size and Growth Total Market Market by Delivery Method
  • 5. Market by Geographical Region Competitive Analysis CHAPTER FIVE: ADJUNCTIVE THERAPIES IN ANESTHESIA Overview Description of Products Neuromuscular Blocking Agents Preanesthetic Sedation and Anesthesia Maintenance Anesthesia Reversal Agents Generic Drug Impact and Availability Research and Development Market Size and Growth Total Market Market by Geographical Region Competitive Analysis CHAPTER SIX: ANESTHESIA DRUGS: TOTAL MARKET SIZE AND FORECAST Total Market Size and Forecast Anesthesia Market by Product Type Anesthesia Market by Geographical Region Competitor Analysis CHAPTER SEVEN: ISSUES AND TRENDS AFFECTING THE ANESTHESIA DRUG MARKET Introduction Regulation of Anesthesia Drugs Dentistry and Anesthesia Anesthesia and Complications in Pediatric Applications Allergic Reactions in Anesthesia Recent Propofol Recall Anesthesia and the Benefits to Depression Patients Anesthesia and Sleep Gender Differences in Anesthesia Reaction Trends in Conscious Sedation
  • 6. Long-term Effects of Anesthesia CHAPTER EIGHT: CORPORATE PROFILES Introduction Abbott Laboratories AstraZeneca Baxter International Eisai Co Endo Pharmaceuticals Holdings, Inc Hospira, Inc Merck/Schering-Plough Roche List of Companies LIST OF EXHIBITS CHAPTER ONE: Executive Summary Table 1-1: The Total World Market for Anesthesia Drugs 2007-2014 Figure 1-1: The Total Market for Anesthesia Drugs 2007-2014 CHAPTER TWO: Introduction The World Anesthesia Drug Market Table 2-1: World Population by Selected Geographical Region, 2010-2050 Figure 2-1: World Population by Selected Geographical Region, 2010-2050 Table 2-2: Procedures by Type, Average Annually 2006-2009 Figure 2-2: Procedures by Type Worldwide, Average Annually 2006-2009 Figure 2-3: Procedures by Type U.S., Average Annually 2006-2009 Table 2-3: Worldwide Anesthesia Complications and Related Mortality Figure 2-4: Worldwide Anesthesia Complications and Related Mortality CHAPTER THREE: General Anesthesia Table 3-1: Marketed Brands for General Anesthesia Drugs (Brand Name, Generic Name, and Manufacturer) Table 3-2: Selected Generic Drug Manufacturers and Products for General Anesthesia Table 3-1: Brand vs. Generic General Anesthetic Market 2007-2009 Table 3-3: General Anesthesia Drugs in Development
  • 7. Table 3-4: The Market for General Anesthesia Drugs 2007-2014 Figure 3-2: The Market for General Anesthesia Drugs 2007-2014 Table 3-5: The Market for General Anesthesia Drugs Estimated Products Sales by Delivery Method, 2009 Figure 3-3: The Market for General Anesthesia Drugs Market Share by Delivery Method, 2009 Table 3-6: The Market for General Anesthesia Drugs Estimated Products Sales by Geographic Region, 2009 Figure 3-4: The Market for General Anesthesia Drugs Market Share by Geographic Region, 2009 Table 3-7: The Market for General Anesthesia Drugs Estimated Revenues and Market Share of Leading Suppliers 2007-2009 Figure 3-5: The Market for General Anesthesia Drugs Estimated Market Share by Leading Suppliers 2009 CHAPTER FOUR: Local Anesthesia Table 4-1: Selected Marketed Local Anesthesia Drugs (Brand Name, Generic Name and Manufacturer) Table 4-2: Selected Generic Drug Manufacturers and Products for Local Anesthesia Table 4-1: Brand vs. Generic Local Anesthetic Market 2007-2009 Table 4-3: Local Anesthesia Drugs in Development Table 4-4: The Market for Local Anesthesia Drugs 2004-2011 Figure 4-2: The Total Market for Local Anesthesia Drugs 2004-2011 Table 4-5: The Market for Local Anesthesia Drugs Estimated Products Sales by Delivery Method, 2009 Figure 4-3: The Market for Local Anesthesia Drugs Market Share by Delivery Method, 2009 Table 4-6: The Market for Local Anesthesia Drugs Estimated Products Sales by Geographic Region, 2009 Figure 4-4: The Market for Local Anesthesia Drugs Market Share by Geographic Region, 2009 Table 4-7: The Market for Local Anesthesia Drugs Estimated Revenues and Market Share of Leading Suppliers 2007-2009 Figure 4-5: The Market for Local Anesthesia Drugs Estimated Market Share by Leading Suppliers 2009 CHAPTER FIVE: Adjunctive Therapies in Anesthesia
  • 8. Table 5-1: Selected Marketed Adjunctive Therapies in Anesthesia (Type, Brand Name, Generic Name, and Manufacturer) Table 5-2: Selected Generic Drug Manufacturers and Products for Adjunctive Therapies in Anesthesia Table 5-1: Brand vs. Generic Adjunctive Therapies in Anesthesia Market 2007-2009 Table 5-3: Adjunctive Therapies in Anesthesia in Development Table 5-4: The Market for Adjunctive Therapies in Anesthesia 2007-2014 Figure 5-2: The Market for Adjunctive Therapies in Anesthesia 2007-2014 Table 5-5: The Market for Adjunctive Therapies in Anesthesia Estimated Products Sales by Geographic Region, 2009 Figure 5-3: The Market for Adjunctive Therapies in Anesthesia Market Share by Geographic Region, 2009 Table 5-6: The Market for Adjunctive Therapies in Anesthesia Estimated Revenues and Market Share of Leading Suppliers 2009 Figure 5-4: The Market for Adjunctive Therapies in Anesthesia Estimated Market Share by Leading Suppliers 2009 CHAPTER SIX: Anesthesia Drugs: Total Market Size and Forecast Table 6-1: The Total World Market for Anesthesia Drugs 2007-2014 Figure 6-1: The Total Market for Anesthesia Drugs 2007-2014 Table 6-2: Anesthesia Drug Market by Type 2007-2014 Figure 6-2: Anesthesia Drug Market by Type 2007-2014 Figure 6-3: Anesthesia Drug Market by Type 2009 Figure 6-4: Anesthesia Drug Market by Type 2014 Table 6-3: Anesthesia Drug Market Estimated Products Sales by Geographic Region, 2009 Figure 6-5: Anesthesia Drug Market Market Share by Geographic Region, 2009 125 Table 6-4: Leading Suppliers Anesthesia Revenues and Significant Segments of Participation, 2009 Figure 6-6: Leading Suppliers—Anesthesia Revenues, 2009 Available immediately for Online Download at http://www.marketresearch.com/product/display.asp?productid=2614802
  • 9. US: 800.298.5699 UK +44.207.256.3920 Int'l: +1.240.747.3093 Fax: 240.747.3004