1. Lupus and the Lung G Diaz-Fuentes, MD Pulmonary & Critical Division Bronx Lebanon Hospital Center

5. Which organs Lupus can affect ? ANY organ of the body can be affected !!

6. Inflammation caused by lupus may affect the lungs in many ways, and can involve the membrane lining of the lungs, the lungs themselves, the blood vessels within the lungs, and the diaphragm. Lupus and the Pulmonary System

8. 1- Pleura- sac lining the lungs - Pleuritis – inflammation and pain - Accumulation of fluid 2- Lungs - Pneumonitis- Inflammation - Bleeding and alveolar hemorrhage - Scarring of the lungs 3- Muscles around the lung - Inflammation and scarring- atelectasis Pulmonary complications of Lupus

9. Cardio-Pulmonary complications of Lupus 4- Lung blood vessels - Pulmonary emboli- blood clots - Pulmonary arterial hypertension 5- Cardiac complications - High blood pressure - Pericarditis- sac around heart - Pericardial effusion - Heart disease

10. Other Pulmonary complications of Lupus 1- Bacterial pneumonia 2- Complications of drugs used for treatment of lupus - Pneumonitis- Inflammation - Infections

15. 28 year old lady with history of lupus affecting the joints and skin January 2008 August 2009

17. For most people with lupus, proper treatment can minimize symptoms, reduce inflammation and pain, and stop the development of serious organ damage Remember The lung problem can be due to - the disease himself - direct complication of the drugs used to treat the disease - complications due to weak immune system due to the treatment or the disease How do we treat the pulmonary problems?

18. 1- Medications to treat lupus - Anti-Inflammatory - Corticosteroids - Immunosuppressives medication 2- Anticoagulants (blood thinners)- for blood clots and pulmonary hypertension 3- Antibiotics in case of infections 4- Experimental drugs Treatment options

24. Thanks