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Eclapsia
1. Eclampsia Drill
Dr Sharda Patra( Asso. Prof)
Prof Manju Puri
Department of Obstetrics & Gynecology
Lady Hardinge Medical College & Smt SK Hospital
New Delhi
2. Eclampsia Drill
Eclampsia is an important obstetric
emergency which if not managed promptly
can lead to life-threatening complications
like cerebral haemorrhage, pulmonary
edema, abruptio placentae maternal and
fetal death
Any pregnant woman presenting
with convulsions in later half of
pregnancy should be treated as
eclampsia until proved otherwise
3. The management of eclampsia
involves
Immediate
management
Subsequent management
One should remember that first few
minutes following a fit are very crucial and
should be handled very fast due to risk of
cerebral hypoxia and aspiration which can
have serious consequences.
.
6. Initial Resuscitation
Airway
Place the woman on her left side to reduce the risk of
aspiration of secretions, vomit and blood
Put
an airway in between the tongue and palate to
prevent tongue bite and falling of tongue
Suction
of the secretions is done through this airway by
connecting it to a suction machine.
Give
oxygen (if available15 l /min ) and continue longer if
cyanosis persists
Stay with the patient to ensure that her airway is
clear
7. Initial Resuscitation
Breathing
Assess – count respiratory rate .Look,
Listen, Feel. Ventilate if necessary
Circulation
Assess pulse , BP. CPR if necessary
intravenous access with a cannula (16G )
Send blood for BG, CBC, platelets, clotting screen,
KFT, LFT, Uric acid, Serum electrolytes
Catheterize the patient to empty the bladder , record
output and monitor output subsequently
Do a urine examination for proteins
Secure
8. Treat and prevent further fits
Administer Magnesium Sulphate
(MgS04)
Regimes: Pritchard or Zuspan
9. Pritchard
Loading dose
Maintenance dose
4g IV 20% solution over 5
to 10min plus 10g IM
(5 g 50% solution deep
I/M in each buttock)
5g I/M every 4h in
alternate buttock till 24
hrs after the last seizure
or delivery which ever is
later
Zuspan
Loading dose
Maintenance dose
Loading dose 4g IV 20% 1 to 2 g / h by controlled
solution over 5 to 10min infusion pump x 24h
after the last seizure
10. Mg So4 :Preparation and
Administration
MagSo4
available in 25%, 50% strength
Initial loading dose 14gms
14gms
4gm IV
10 gms IM
11. Preparation and administration
25% ampoules
(2ml) contains
0.5 gm magso4
IV 4gms
50% amps (2ml)
contains 1gm of
magso4
Take 4amps (8ml)
dilute with 12ml
saline to make it
20ml
Take 8amps (16ml)
dilute with 4ml saline
to make it 20ml
20ml solution contains 4gms
Magso4
( 4gm/20ml 20% Sol)
IV 4gm
20ml is given slow IV
over 5-10mins
Keep an eye on
respiratory rate ,
facial flushing ,
14. Monitoring during magnesium sulphate
Therapy
Respiratory rate >14/ min
Presence of patellar reflexes (knee jerk)
Urinary output- 25ml/hr or 100ml/4hrs
Repeat doses of magnesium sulphate
must be withheld or delayed if:
The respiratory rate is less than 14 per
minute
Patellar reflexes are absent
Urinary output is less than 100 ml over
preceding 4 hours
15. Antidote:
In case of respiratory depression or
arrest:
Give calcium gluconate 1 g (10 ml of 10%
solution) IV slowly
Assisted ventilation using mask and bag,
anesthetic apparatus or intubation
16. CAUTION
Magnesium sulfate should be used with
caution in women with
Impaired renal function.
Patients with a heart block or myocardial
damage including a history of cardiac
ischaemia
17. Controlling blood pressure
Antihypertensive
drugs should be given if
the diastolic blood pressure is 110 mmHg
or more.
The aim is to keep the diastolic blood
pressure between 90–100 mmHg to
prevent cerebral haemorrhage
Drug of choice- Labetolol, Nifedepin
18. Labetolol
1.
20 mg I.V over 2mins
wait for 10 mins if no response
40 mg iv
80 mg iv
(can be increased upto 220 mg)
2.
10 mg IV
20 mg iv
40 mg iv
Target :
Decrease in diastolic BP
To 90-100 mgHg
40 mg iv
80 mg iv
20. Subsequent management
Once
the patient is stabilized and fits
have ceased , then a pervaginum
examination is done to assess cervical
status
Consider
for termination of pregnancy if
not in labor
21. Essential care
Turning
the woman two–hourly to avoid
hypostatic pneumonia
mouth care, (no oral fluids are given)
monitor the urinary output.
22. Observations:
Restlessness
or twitching which may herald
the onset of another fit
Color is observed for cyanosis which
indicates the need for oxygen
Temperature four hourly. Hyperpyrexia may
occur
Pulse and respirations are recorded hourly,
or more often
Blood pressure is recorded at least hourly
earlier if >=160/110
Ut contractions and FHS is checked
Input output is recorded accurately.
23. A
L
G
O
R
I
T
H
M
Do not leave the patient
alone
Place in left lateral position
CALL FOR HELP
Airway
Assess
Maintain patency
Give oxygen
Breathing
Assess
Protect Airway
Ventilate if required
Circulation
Evaluate pulse and BP
Secure IV access
24. Control of
convulsions
Control of
Hypertension
Loading dose :
4gm IV
20ml is given slow IV over 5-10mins followed by 10gms ,
5gms deep IM (10ml) in each buttock
If fits recur- 2gms , 20% IV
Maintenance dose- 5gms IM in alternate buttocks 4 hourly
Monitor- Resp rate>16
Presence of Knee jerk
Urinary output >25ml/1hr
If Mag toxicity- Inj Calcium Gluconate , 10% 10ml , 10mins
IV
Labetolol
10mg IV , give 20mg IV if noresponse after 10mins, then
40mg, 40mg, 80mg max 220mg
Nifedipine
10mg orally , repeat after 20mins if noresponse , max 200
mg, target BP- dbp-90-100 mmHg
Delivery
25. A DRILL …….. Eclampsia
The
need for good clinical skills to be able
to recognize and act promptly
Be in control of the situation
Need to care for the family, who will be
extremely distressed to see the woman have
a fit;
Need for gentleness, so as not to harm the
woman if she is unconscious, or stimulate
further fits;
Need to respect the woman’s dignity at all
times;
Need for strict attention
26. &
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