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Epidemiology  Presentation about " Coffee consumption and pancreatic cancer "
Epidemiology ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Objectives ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Q1. Aim of the study: ,[object Object]
Q1. cont… ,[object Object]
Q2. What was the study design? ,[object Object],[object Object],[object Object],[object Object]
Cont… Q2 A. ,[object Object],[object Object],[object Object]
Cont… Q2 A ,[object Object],[object Object]
Q2. B.Do you know exactly what was done? ,[object Object]
Cont…Q2. B. ,[object Object]
Q2.C.Who were the study population: ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],Q3. A. what was the main exposure under investigation?
Q.3.B. how was it defined and measured in this study? ,[object Object],[object Object]
Q.3 .C. Method of measurement – precision? Validity? ,[object Object]
Q4. A. what was the main out come under investigation? P-value Adjusted interval Confidence interval R.R Variable (P~0.001) After adjustment for cigarette smoking Men 1.4 Women 1.5 1.1 to 1.9 1.4 % Tobacco Men 1.3 Women 0.8 0.6- 1.3 0.9 Alcohol Men 0.7 Women o.7 Men 0.5 -1.1 Women 0.5-1.2 - Tea P  0.001 Men 2.6 Women 2.3 Men 2.6 Women 1.2-4.6 2 cups 1.7 3 or more 2.7 coffee
Cont.. Q4. A ,[object Object],[object Object],[object Object],[object Object],[object Object]
B. how was it defined and measured in this study? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
C. Method of measurement – precision? Validity? ,[object Object],[object Object]
Q5. What possible confounding factors might there be? Were these measured? Exposure Coffee consumptions Confounder Alchol Smoking Tea Sex (men,women) Age Life style Pancreatic cancer
Cont… Q 5 ,[object Object],[object Object]
Q 6. A. data presentation and analysis- how clear and complete? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Cont.. Q6.A. ,[object Object]
Cont.. Q6.A. ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Characteristics of control pts with other disorder: ,[object Object],[object Object]
Q 6.B. complete presentation of numbers: No. Excluded from study No. Cases 8 Non-white 578 identified 4 Residents of other countries 405 interviewed 8 Pt. older than 79y 20 died 16 Whose interview information was questionable reliability 33 Discharged before interview 78 Too sick 369 pts. Analysis based on data from the remaining 14 Language difficulties 26 Refused to interview
Two principal diagnostic groups No. 371-pt. with other disorder No. 273-pt.with other pancreas&biliary tract No. Controls: 70 Hernia 65 Breast tumor 1118 Eligible pt. 41 Colitis enteritis or diverticulities 60 Colon 700 interviewed 26 Bowel obstruction,adhesion,fistula 25 Rectum 9 Died 17 gastritis 24 Stomach 131 Discharged before interview 47 Other gastroenterologic 9 Small intestine 179 Too ill 29 Benign tumor 8 Ovary 26 Language problems 21 Varicose vein,phlebities 8 Prostate 73 refused 20 Genitourinary disorder 7 Cervix 20 Neurological disorder 16 Melanoma 16 Gyrecologic disorders 15 Lymphoma 64   Other conditions
Cont.. Q6 B The analysis consisted of 644 pt. The analysis consisted of 644 pt. The analysis consisted  of 644 pts No. Exclusions 17 Non-white 5 Foreign resident 4 Older than 79y 30 Whose interview un reliable
  Q6. C. measure if association and risk: ,[object Object]
Q6. D. Statistical significance: ,[object Object]
Q6. E.Control for confounders and bias: ,[object Object]
Cont… Q6.E. ,[object Object],[object Object]
Q 7. Could the observation observed be due to ,[object Object],[object Object],[object Object],[object Object]
Cont.. Q7 ,[object Object],[object Object],[object Object]
Q8. A. Conclusions ,[object Object],[object Object]
Cont… Conclusions ,[object Object],[object Object]
Q8. B. How genaralizable do you thinks the variables are? ,[object Object]
Q8. C. is the interpretation of results, and hence, the conclusions justified? ,[object Object],Women men 2.3 2.6 Adjusted relative risk 1.2-4.6 1.2-5.4 Confidence interval
Table conclusion ,[object Object]
Q9. Abstract: does this clearly and fairly summarized what is shown in the paper? ,[object Object]
Q10. How would you do this study better? ,[object Object],[object Object],[object Object],[object Object],[object Object]
 

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Presentation epi

  • 1. Epidemiology Presentation about " Coffee consumption and pancreatic cancer "
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  • 15. Q4. A. what was the main out come under investigation? P-value Adjusted interval Confidence interval R.R Variable (P~0.001) After adjustment for cigarette smoking Men 1.4 Women 1.5 1.1 to 1.9 1.4 % Tobacco Men 1.3 Women 0.8 0.6- 1.3 0.9 Alcohol Men 0.7 Women o.7 Men 0.5 -1.1 Women 0.5-1.2 - Tea P 0.001 Men 2.6 Women 2.3 Men 2.6 Women 1.2-4.6 2 cups 1.7 3 or more 2.7 coffee
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  • 19. Q5. What possible confounding factors might there be? Were these measured? Exposure Coffee consumptions Confounder Alchol Smoking Tea Sex (men,women) Age Life style Pancreatic cancer
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  • 25. Q 6.B. complete presentation of numbers: No. Excluded from study No. Cases 8 Non-white 578 identified 4 Residents of other countries 405 interviewed 8 Pt. older than 79y 20 died 16 Whose interview information was questionable reliability 33 Discharged before interview 78 Too sick 369 pts. Analysis based on data from the remaining 14 Language difficulties 26 Refused to interview
  • 26. Two principal diagnostic groups No. 371-pt. with other disorder No. 273-pt.with other pancreas&biliary tract No. Controls: 70 Hernia 65 Breast tumor 1118 Eligible pt. 41 Colitis enteritis or diverticulities 60 Colon 700 interviewed 26 Bowel obstruction,adhesion,fistula 25 Rectum 9 Died 17 gastritis 24 Stomach 131 Discharged before interview 47 Other gastroenterologic 9 Small intestine 179 Too ill 29 Benign tumor 8 Ovary 26 Language problems 21 Varicose vein,phlebities 8 Prostate 73 refused 20 Genitourinary disorder 7 Cervix 20 Neurological disorder 16 Melanoma 16 Gyrecologic disorders 15 Lymphoma 64   Other conditions
  • 27. Cont.. Q6 B The analysis consisted of 644 pt. The analysis consisted of 644 pt. The analysis consisted of 644 pts No. Exclusions 17 Non-white 5 Foreign resident 4 Older than 79y 30 Whose interview un reliable
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Notas do Editor

  1. 01/23/11