4. Legend
TOSA Counties = DSA (Donor Service Area)
■ = Southern Region
▲ = Northern Region
● = Central Region
Colors = Various levels of Demographic
21. The New Question
After looking at the previous data, we can see that
TOSA has a very different demographic make up
than other OPOs.
A new question is looked at:
What are the odds of a Hispanic in the TOSA OPO being
on the donor registry?
The odds of a Caucasian?
22. Data
Case-Control Study
9049 referrals between 2012 and first half of 2014
(18 months)
Case: Registry referral
Control: Non-Registry referral
Variable of interest: Race/Ethnicity
Hispanic/Latino vs. Non-Hispanic
(Non-Hispanic) Caucasian vs. Non-Caucasian
Data compiled by Todd Morefield and Eric Elliott
23. Odds Ratio
Outcome No
Outcome
Total
Variable A B A+B
No
Variable
C D C+D
Total A+C B+D A+B+C+
D
• An odds ratio is the probability of the outcome given
that the variable is present divided by the probability of
the outcome given that the variable is not present.
• OR =
𝐴𝐷
𝐵𝐶
• This can be calculated using a 2x2 table, shown below:
24. Odds Ratio Meaning
Odds Ratio > 1 (Confidence Interval > 1)
There is a positive association between the outcome and
the variable.
Odds Ratio < 1 (Confidence Interval < 1)
There is a negative association between the outcome and
the variable.
Odds Ratio = 1 (Confidence Interval contains 1)
There is no association between the outcome and the
variable.
25. Hispanics 2x2 Table
Registry Non-Registry Total
Hispanic 155 4498 4653
Non-Hispanic 408 3988 4396
Total 563 8486 9049
26. Odds Ratio
OR =
𝐴𝐷
𝐵𝐶
=
(155)(3988)
(4498)(408)
= 0.337
95% Confidence Interval = (0.279, 0.407)
Interpretation:
Hispanics in the TOSA counties are between
0.279 and 0.407 times less likely than Non-
Hispanics to be on the donor registry, on
average, with 95% confidence.
This is a very low odds ratio. There is a
negative association between being Hispanic
and being on the donor registry.
27. Caucasians 2x2 Table
Registry Non-Registry Total
Caucasian 361 3171 3532
Non-Caucasian 202 5315 5517
Total 563 8486 9049
28. Odds Ratio
OR =
𝐴𝐷
𝐵𝐶
=
(361)(5315)
(3171)(202)
= 2.995
95% Confidence Interval = (2.508, 3.578)
Interpretation:
Non-Hispanic Caucasians in the TOSA
counties are between 2.508 and 3.578 times
more likely than Non-Caucasians to be on the
donor registry, on average, with 95%
confidence.
This is a very high odds ratio. There is a
positive association between being Caucasian
and being on the donor registry.
29. Odds Ratios per TOSA DSA
TOSA DSA Odds Ratio Lower 95% Upper 95%
Central 0.440 0.333 0.531
North 0.521 0.365 0.744
South 0.311 0.182 0.531
Hispanics vs. Non-Hispanics
30. Odds Ratios per TOSA DSA
TOSA DSA Odds Ratio Lower 95% Upper 95%
Central 2.595 1.984 3.396
North 2.040 1.527 2.726
South 2.884 1.655 5.025
Caucasians vs. Non-
Caucasians