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Using IT to Improve
    Warfarin Management
      in the Hutt Valley

                Dr Garry Brown (Clinical Director) &
                    Richard Kelly (IT Specialist)
                     www.kowhaihealth.org.nz
                     Friday, 16th March 2007




            In a nutshell…
..................................................................
     • Warfarin is one of the 5 highest risk drugs in
       clinical use
     • Management of warfarin is highly complex
       Significant sources of avoidable error arise from
       – information flow issues from secondary to
         primary care
       – practice system issues
       – patient compliance issues
     • Use the power of IT, and the principles of the
       Primary Health Care Strategy to improve
       system wide management of warfarin patients




                                                                     1
Primary Health Care Strategy
..................................................................
   • Co-ordinate care across service areas
   • Offer access to comprehensive services
   • Continuously improve quality using good
     information
   • Identify and remove inequalities
   • Develop the primary care workforce
   • Work with local communities




   Warfarin is a High Risk Drug
..................................................................




                                                                     2
Warfarin is a High Risk Drug
..................................................................
   • Levels measured by International
     Normalised Ratio (INR)
   • Levels too low lead to excess blood
     clotting eg embolic stroke, DVT
   • Levels too high lead to excess bleeding
     problems eg haemorrhagic stroke, GI
     bleeding




        Maintenance Therapy
        Risk of Intracranial Hemorrhage in Outpatients




                                                Adapted from: Hylek EM, Singer DE, Ann Int Med 1994;120:897
                                                                                                      -902

    Hylek, et al, studied the risk of intracranial hemorrhage in out patients treated with warfarin.
    They determined that an intensity of anticoagulation expressed as a p rothrombin time ratio
    (PTR) above 2.0 (roughly corresponding to an INR of 3.7 to 4.3) resulted in an increase
    in the risk of bleeding.




                                                                                                              3
Lowest Effective Intensity for Warfarin Therapy for
       Maintenance Therapy
           Stroke Prevention in Atrial Fibrillation




                INR below 2.0 results in a higher risk of stroke


                                                                   Hylek EM, et al. NEJM 1996;335:540
                                                                                                  -546.
                                                                                                  -546.




   Whose problem is it?
..................................................................
   .




                                                                                                          4
The Solution
..................................................................




               The Solution
..................................................................
     • Address information flow issues via
       Concerto, Healthlink
     • Address practice system issues using
       MedTech template, and additional education
       and knowledge resources
     • Address patient compliance issues using
       Patient Defaulters database from Aotea
       Pathology




                                                                     5
The Solution
..................................................................
     • Hutt Valley
       DHB and
       Concerto




               The Solution
..................................................................




                                                                     6
The Solution
..................................................................
     • Hutt
       Valley
       DHB
       Discharge
       summary




                The Solution
..................................................................
     • MedTech
       screening
       template
       (at GP
       Practice)




                                                                     7
The Solution
..................................................................
     • Aotea Pathology defaulters database




               The Solution
..................................................................




                                                                     8
The Solution
..................................................................
     • Sample of
       fax sent
       to Practices
       with details
       of their
       defaulting
       patients




                      Results
..................................................................
     • Reduction in patients defaulting for INR
       testing from 8.3 % down to <3% of all
       patients (1200 in Hutt Valley area)

     • Reliable, accurate, complete, and timely
       flow of critical clinical information from
       hospital to primary care
     • Improved practice systems using
       MedTech templates




                                                                     9
The Future
..................................................................
     • Dealing with patients who have no GP
     • Can we extend this systems approach
       for other high risk drugs eg: amiodarone
       > a pilot is in progress
     • Text/email patient INR test reminders
     • Linking to Point of Care testing
     • Using Web hosted decision support tools
       > in development by BPAC




                                                                     10
11

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Using IT to Improve Warfarin Management in the Hutt Valley

  • 1. Using IT to Improve Warfarin Management in the Hutt Valley Dr Garry Brown (Clinical Director) & Richard Kelly (IT Specialist) www.kowhaihealth.org.nz Friday, 16th March 2007 In a nutshell… .................................................................. • Warfarin is one of the 5 highest risk drugs in clinical use • Management of warfarin is highly complex Significant sources of avoidable error arise from – information flow issues from secondary to primary care – practice system issues – patient compliance issues • Use the power of IT, and the principles of the Primary Health Care Strategy to improve system wide management of warfarin patients 1
  • 2. Primary Health Care Strategy .................................................................. • Co-ordinate care across service areas • Offer access to comprehensive services • Continuously improve quality using good information • Identify and remove inequalities • Develop the primary care workforce • Work with local communities Warfarin is a High Risk Drug .................................................................. 2
  • 3. Warfarin is a High Risk Drug .................................................................. • Levels measured by International Normalised Ratio (INR) • Levels too low lead to excess blood clotting eg embolic stroke, DVT • Levels too high lead to excess bleeding problems eg haemorrhagic stroke, GI bleeding Maintenance Therapy Risk of Intracranial Hemorrhage in Outpatients Adapted from: Hylek EM, Singer DE, Ann Int Med 1994;120:897 -902 Hylek, et al, studied the risk of intracranial hemorrhage in out patients treated with warfarin. They determined that an intensity of anticoagulation expressed as a p rothrombin time ratio (PTR) above 2.0 (roughly corresponding to an INR of 3.7 to 4.3) resulted in an increase in the risk of bleeding. 3
  • 4. Lowest Effective Intensity for Warfarin Therapy for Maintenance Therapy Stroke Prevention in Atrial Fibrillation INR below 2.0 results in a higher risk of stroke Hylek EM, et al. NEJM 1996;335:540 -546. -546. Whose problem is it? .................................................................. . 4
  • 5. The Solution .................................................................. The Solution .................................................................. • Address information flow issues via Concerto, Healthlink • Address practice system issues using MedTech template, and additional education and knowledge resources • Address patient compliance issues using Patient Defaulters database from Aotea Pathology 5
  • 6. The Solution .................................................................. • Hutt Valley DHB and Concerto The Solution .................................................................. 6
  • 7. The Solution .................................................................. • Hutt Valley DHB Discharge summary The Solution .................................................................. • MedTech screening template (at GP Practice) 7
  • 8. The Solution .................................................................. • Aotea Pathology defaulters database The Solution .................................................................. 8
  • 9. The Solution .................................................................. • Sample of fax sent to Practices with details of their defaulting patients Results .................................................................. • Reduction in patients defaulting for INR testing from 8.3 % down to <3% of all patients (1200 in Hutt Valley area) • Reliable, accurate, complete, and timely flow of critical clinical information from hospital to primary care • Improved practice systems using MedTech templates 9
  • 10. The Future .................................................................. • Dealing with patients who have no GP • Can we extend this systems approach for other high risk drugs eg: amiodarone > a pilot is in progress • Text/email patient INR test reminders • Linking to Point of Care testing • Using Web hosted decision support tools > in development by BPAC 10
  • 11. 11