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Population and social conditions                                                                Statistics in focus
                                                                                                7/2012
Authors: Hartmut BUCHOW, Elodie CAYOTTE
            and Lucian AGAFITEI




Circulatory diseases - Main causes of death for
persons aged 65 and more in Europe, 2009
For people of 65 years and older (65+), the main                        -        Respiratory diseases – there is a heterogeneous
causes of death are circulatory diseases, such as                                distribution for this complex group of causes of
ischaemic heart diseases and cerebrovascular                                     death
diseases, followed by cancers. For those of less
                                                                        -        Lung cancer – this disease has the highest
than 65 years there is a difference by gender: for
                                                                                 gender difference among the main causes of
men circulatory diseases prevail, while women die
                                                                                 death, as it accounts for four times as many
almost twice as often from cancers than from
                                                                                 deaths in men as in women
circulatory diseases.
                                                                        -        Colorectal cancer – there are no striking
National and regional distributions of causes of
                                                                                 regional or gender differences
death in people of 65+ indicate the following:
- Circulatory diseases – eastern European                               -        Breast and prostate cancer – death rates show
   countries have the highest death rates                                        a considerable decrease over time

Causes of death (COD) among the over-65 age-group                       health programmes throughout Europe are largely
are of increasing significance in European mortality                    aimed at the reduction of mortality before the age of
statistics. A dramatic change in the nature of health                   65 by preventive measures. They promote a healthier
care over the past century has resulted in longer life                  life style with improved nutrition, lower tobacco and
spans, but also greater prevalence of chronic illnesses.                alcohol consumption, an increase in physical activity
This has increased the demands on the health care                       and reduction of professional risks. In 2009 more than
system, particularly for the treatment of ongoing                       3.8 million deaths in the EU-27 occurred after the age
illnesses and for long-term care. In addition, public                   of 65, 80.3 % of total deaths.

Figure 1: Major causes of death for persons under 65 years and aged 65 and more – standardised death rates
(SDR) per 100 000 inhabitants, EU-27, 2009


  800                                                                                                                                             32
                                                                                                         Males aged 65+ (left axis)
  700                                                                                                    Females aged 65+ (left axis)             28

                                                                                                         Males aged less than 65 (right axis)
  600                                                                                                                                             24
                                                                                                         Females aged less than 65 (right axis)
  500                                                                                                                                             20

  400                                                                                                                                             16

  300                                                                                                                                             12

  200                                                                                                                                             8

  100                                                                                                                                             4

    0                                                                                                                                             0
          Ischaemic heart   Cerebrovascular     Diseases of the    Lung cancer       Colorectal cancer       Breast Cancer    Prostate cancer
             diseases          diseases       respiratory system                                             (women only)       (men only)


Source: Eurostat (online data code: hlth_cd_asdr)
The percentage of the population aged 65+ in the EU-           Between 2000 and 2009 there was a reduction of 26%
27 is projected on average to increase from 16.0% in           in EU-27 death rates resulting from ischaemic heart
2010 to 29.0 % in 2060 (see: The greying of the baby           diseases and cerebrovascular diseases. Nevertheless,
boomers. SIF: KS-SF-11-023).                                   as shown in figure 1, for people of 65+ these
                                                               circulatory diseases are still the main causes of death.
It is therefore interesting to focus on the major causes
                                                               For those of less than 65 years the situation is
of death for that age group.
                                                               different: while for men there is still a slight
This publication addresses seven major COD for                 predominance of deaths by circulatory diseases (ratio
persons aged 65+: 2 main disease groups of the                 1.2), women die almost twice as often from lung,
circulatory system, ischaemic heart diseases (such as          colorectal and breast cancers than from circulatory
heart attacks) and cerebrovascular diseases (such as           diseases.
strokes); the group of respiratory diseases, and
4 malignant neoplasms: lung cancer 1, colorectal,
breast and prostate cancer.



1
    Including neoplasm in larynx, trachea, bronchus and lung




Gender differences in people of 65+ highest for lung cancer
Going into gender differences for the seven COD                Figure 2: Lung cancer for EU-27 by gender, SDR per
studied, the main difference between men and women             100 000 inhabitants
is for lung cancer. For ages 65+ the ratio of                  450                                                                                             40
Standardised Death Rates (SDR) for men to women is             400                                                                                             35
5.0 in the year 2000, falling to 3.8 in 2009, see figure       350
                                                                                                                                                               30
2. It reflects a definite trend over time: while for
                                                               300
women of both age groups the EU-27 SDR goes up                                                                                                                 25
                                                               250
from 8.3 to 10.2 (ages less than 65) and from 81.1 to                                                                                                          20
                                                               200
92.4 (ages 65+), respectively, the trend for men is the                                                                                                        15
reverse, from 33.1 to 27.3 for the younger and from            150
                                                                                                                                                               10
402.7 to 352.1 for the older age groups.                       100

                                                                50                                                                                             5

                                                                 0                                                                                             0
                                                                     2000    2001    2002     2003        2004   2005     2006     2007    2008     2009
                                                                     Males 65 years or over (left axis)                 Females 65 years or over (left axis)
                                                                     Males less than 65 years (right axis)              Females less than 65 years (right axis)

                                                               Source: Eurostat (online data code: hlth_cd_asdr)




National differences in causes of death for the elderly in EU-27
For the EU-27 the SDR for people of 65+ is highest             COD: here the third major COD is lung cancer and
for ischaemic heart diseases with 568.8 per                    the fourth major COD is colorectal cancer (EE, LV).
100 000 inhabitants, followed by cerebrovascular               PT is the only country where lung cancer is not
diseases (397.4), respiratory diseases (326.0) and lung        among the four major COD.
cancer (201.2).
                                                               The findings indicate a skew for circulatory diseases
However, only 13 countries are strictly in line with           towards eastern Europe. SDR of more than 900 per
that pattern. For six countries cerebrovascular                100 000 inhabitants were reported for ischaemic heart
diseases rank first among COD (BG, EL, LU, PT, SI              diseases by CZ, EE, FI, LT, LV, MT, HU, SK, RO
and MK). Four countries reported respiratory diseases          and HR (with highest of more than 2 000 by LT and
in first (BE, DK, ES and NL) and 10 other countries            SK), and for cerebrovascular diseases by BG, LV, RO
in second place (DE, EL, IE, FR, CY, LU, PT, UK, IS            and MK. On the other hand only two countries have a
and NO), while two countries do not report                     SDR of less than 300, FR for both disease groups and
respiratory diseases at all as one of the four main            CH for cerebrovascular diseases, see maps 1 and 2.



2                                                                                            7/2012 — Statistics in focus
Table 1: Major causes of death at national level for 65+ years, SDR per 100 000 inhabitants, 2009

            Ischaemic heart Cerebrovascular     Respiratory      Lung cancer    Colorectal Breast cancer Prostate cancer
 Country
             disease (total) diseases (total) diseases (total)      (total)    cancer (total) (females)      (males)
 EU27              568.8          397.4             326.0            201.2        120.4          102.4         167.3
 EU15              463.7          316.7             334.4            197.2        114.3          104.1         166.2
 BE                480.7          340.0             541.6            244.8        121.9          124.1         190.1
 BG                755.6        1 310.2             204.8            137.7        126.8           87.5         133.8
 CZ              1 308.3          640.4             299.3            219.8        173.4          102.1         186.0
 DK                453.2          315.1             524.1            290.0        157.8          151.8         267.6
 DE                632.5          297.3             299.8            178.9        117.4          112.7         162.5
 EE              1 535.9          485.2             129.2            188.1        133.9           92.2         301.6
 IE                759.0          324.2             583.0            247.4        132.5          133.6         220.7
 EL                379.3          611.2             416.1            211.6         85.6          103.7         141.5
 ES                317.7          284.7             395.9            180.0        128.6           74.0         139.9
 FR                235.8          208.0             209.8            165.2        107.9          103.5         169.3
 IT                455.1          388.7             232.3            209.1        110.8          103.7         129.4
 CY                458.4          301.4             311.7            144.5         64.2           88.4         143.3
 LV              1 734.0          977.5              86.2            182.2        136.5           91.6         262.7
 LT              2 250.2          895.8             197.9            178.1        142.3           93.1         241.1
 LU                314.2          376.9             331.6            222.7        138.4          123.5         202.3
 HU              1 523.9          666.4             273.3            273.9        207.1          117.0         171.0
 MT                905.0          485.7             428.6            177.4        113.7          142.1         122.4
 NL                306.1          266.9             426.3            267.8        135.8          119.5         207.8
 AT                749.4          263.2             216.2            160.8        105.6          113.8         174.3
 PL                660.3          516.4             287.3            260.9        139.0           82.9         177.5
 PT                304.7          598.4             510.9            119.7        138.5           79.3         195.0
 RO              1 317.7        1 276.5             260.9            169.5        114.7           88.8         122.9
 SI                444.9          531.2             318.0            204.2        171.7          134.3         281.8
 SK              2 072.4          715.0             338.1            188.7        181.9          100.9         186.2
 FI                934.0          354.0             178.5            155.8         86.9           83.8         188.9
 SE                639.0          325.7             239.1            155.0        113.7           84.0         271.3
 UK                569.6          343.8             539.6            256.1        109.3          113.1         196.1
 IS                666.1          302.6             339.1            238.6        116.5          115.5         259.3
 NO                492.2          310.9             391.1            199.5        144.0           90.4         277.5
 CH                506.3          233.7             215.4            161.1         96.1          106.5         205.9
 HR              1 183.6          897.8             252.3            233.5        186.9          127.6         236.5
 MK                564.8        1 442.9             240.4            186.6        113.4          103.1         138.2
BE: 2005; CH: 2007; FR, IT: 2008
Source: Eurostat (online data code: hlth_cd_asdr)



Regional differences in EU-27 for causes of death (COD) in the elderly
The following maps show differences for the                      was no apparent difference in the geographical
aforementioned COD at regional level (NUTS 2                     pattern, even though the ratio between men and
regions) for the reference years 2006-2008. SDR for              women may vary.
men and women were combined into one map if there


Cerebrovascular and ischaemic heart diseases: Highest COD rates in East-
European regions

For both groups of circulatory diseases the                      less than 250 per 100 000 inhabitants. The
geographical distribution of SDR for people of 65+ is            distributions for men and women are similar in
similar, with highest rates for eastern European                 regions with the highest SDR, such as in regions of
countries.                                                       BG and RO. However, only 18 regions reported rates
                                                                 of less than 250 deaths per 100 000 inhabitants for
For cerebrovascular diseases highest SDR of more
                                                                 men, compared to 42 regions for women (data not
than 1 000 per 100 000 inhabitants are found in
                                                                 shown; for details see Eurostat database).
16 regions of BG, LV, RO and MK, while 31 regions
of AT, DE, ES, FR and CH reported lowest rates of


           Statistics in focus — 7/2012                                                                                    3
Map 1: Deaths due to cerebrovascular diseases in people aged 65 years and more




(¹) MT, UK, CH 2005/2007; BE, 2000/2002; Scotland NUTS1 level; DK, SI, HR national level.
Source: Eurostat (online data code: hlth_cd_ysdr1)


For ischaemic heart diseases the highest SDR (more               higher than 2 500 in LT, LV and SK. Lowest SDR of
than 1 500 per 100 000 inhabitants) are reported from            less than 250 per 100 000 inhabitants are found in 3
17 regions of the Baltic countries, CZ, HU, SK and               regions of FR. On the other hand, for women only 10
RO. The regions with lowest rates (less than 250 per             regions in HU, LT, LV, RO and SK have a SDR of
100 000 inhabitants) are in the south-west of Europe:            more than 1 500 per 100 000 inhabitants, with highest
13 in FR, 2 in PT and one in ES.                                 rate of 2 064 per 100 000 in LT. However, by contrast
                                                                 with the situation for men, 45 regions (11 from ES, 4
The difference in distribution of the highest and
                                                                 from EL, 25 from FR, 2 from PT and 3 from NL)
lowest rates for men and women is more pronounced
                                                                 report a SDR of less than 250 per 100 000, with the
than for cerebrovascular diseases: for men, 27 regions
                                                                 lowest for Guyane (FR, SDR 77.7).
report a SDR of more than 1 500 per
100 000 inhabitants, with 4 regions having rates




4                                                                                      7/2012 — Statistics in focus
Map 2: Deaths due to ischaemic heart diseases in people aged 65 years and more




(¹) MT, UK, CH 2005/2007; BE, 2000/2002; Scotland NUTS1 level; DK, SI, HR national level.
Source: Eurostat (online data code: hlth_cd_ysdr1)



Respiratory diseases: A heterogeneous regional distribution for a complex group
of diseases
For respiratory diseases, which include chronic                  with 1 137 per 100 000 inhabitants, followed by
lower respiratory diseases or asthma as well as                  10 UK regions with rates between 760 and 650 per
infectious diseases such as influenza or pneumonia,              100 000. On the other hand 7 regions in EE, FI, FR
there are some countries with a relatively high SDR              and LV had a rate of 180 per 100 000 and below,
for people of 65+ such as DK, IE, PT or UK, which                with the very lowest of 117.6 for LV.
can be clearly differentiated from those with lower
                                                                 The relation of SDR for men and women varies
SDR such as the Baltic countries, FI and most parts
                                                                 from almost 1:1 in IS to ratios above 4.0 for the
of FR. However, the regional distribution of death
                                                                 Baltic countries, the highest being for LT with 4.5.
rates within the countries for respiratory diseases is
                                                                 The range differs also within the countries, from
quite heterogeneous, but has a much smaller range
                                                                 1.3 to 1.5 in the UK to 1.6-2.8 in FR, 1.7-2.7 in DE
than for circulatory diseases: the highest SDR was
                                                                 or 2.2-3.8 in PL.
reported by Regiao Autonoma de Madeira (PT)
          Statistics in focus — 7/2012                                                                              5
Map 3: Deaths due to diseases of the respiratory system in people aged 65 years and more




(¹) MT, UK, CH 2005/2007; BE 2000/2002; Scotland NUTS1 level; DK, HR, national level.
Source: Eurostat (online data code: hlth_cd_ysdr1)

The scattered picture for this complex group of                  may include differences in environmental
causes of death may partly indicate differences in               conditions including specific work conditions for
reporting and coding practices, which may be less                men, differences in public health campaigns that
relevant for other diseases. In general death                    may not reach all of the elderly, such as
certificates for the elderly are complicated due to              vaccinations against influenza, or differences in
several co-morbidities, with respiratory diseases                reaching for a doctor in rural areas for pneumonia
often playing an important role. Additional reasons              complications in the elderly.




6                                                                                       7/2012 — Statistics in focus
Colorectal cancer: No striking regional or gender differences
SDR for men and women were combined into one                     There seems to be a geographic slope from northern
map as there is no obvious difference in the                     and central European countries to the south: highest
geographical pattern nor in the ratio for men and                SDR with more than 200 deaths per 100 000 can be
women.                                                           noted in CZ, HU and SK. On the other hand SDR
                                                                 with less than 60 per 100 000 inhabitants were
At present colorectal cancer ranks second for
                                                                 reported by FI, EL, and FR, with the lowest rate at
malignant neoplasms affecting both women and men,
                                                                 47.4 for Ipeiros (EL). Low figures for the
following lung cancer. There is an appreciable
                                                                 Mediterranean regions of FR, the whole of EL, MT
downward trend in most of the countries, with
                                                                 and part of IT contrast to higher rates for
slightly more improvement for rectum and anus
                                                                 Mediterranean regions of ES, while low rates are also
cancer, but it remains one of the major scourges for
                                                                 found in 3 regions of FI with less than 73 cases per
the elderly.
                                                                 100 000.

Map 4: Deaths due to colorectal cancer in people aged 65 years and more




(¹) MT, UK, CH 2005/2007; BE 2000/2002; Scotland, NUTS1 level; DK, SI, HR national level.
Source: Eurostat (online data code: hlth_cd_ysdr1)



          Statistics in focus — 7/2012                                                                               7
Lung cancer: A marked gender difference at national and regional level
The fact that rates for lung cancer are much higher              already been mentioned above. This is underlined
for men than for women in the ages 65+ has                       by regional data as shown by the two maps.

Map 5: Deaths due to larynx, trachea, bronchus and lung cancer in men aged 65 years and more




(¹) MT, UK, CH 2005/2007; BE 2000/2002; Scotland NUTS1 level; DK, SI, HR national level.
Source: Eurostat (online data code: hlth_cd_ysdr1)




8                                                                                     7/2012 — Statistics in focus
Map 6: Deaths due to larynx, trachea, bronchus and lung cancer in women aged 65 years and
more




(¹) MT, UK, CH 2005/2007; BE 2000/2002; Scotland NUTS1 level; DK, SI, HR national level.
Source: Eurostat (online data code : hlth_cd_ysdr1)

In 11 out of 32 European countries covered by the                For people of 65+ maps 5 and 6 indicate highest SDR
data the SDR for lung cancer is 6 or more times                  for men in eastern and south-western Europe plus
higher for men of 65+ than for women, with MT                    northern UK on the one hand and an incline from
having the highest ratio at 12.6. However, for those             north-east to south-west for women on the other hand.
less than 65 years almost all countries report a                 That difference in SDR for women is also reflected in
shrinking gender difference: only 4 countries have               the ratios men to women, which are highest with 9
ratios of 6 and higher, the highest being for LV at              and more for regions in EL, ES, FR, IT and PT, but
almost 12 times more for men than for women.                     also in LT, while ratios of 2 down to 1 are found in
                                                                 DE, IE, IS, NO, SE, and the UK.




          Statistics in focus — 7/2012                                                                              9
Breast and Prostate Cancer: A noticeable decrease over time
After the diseases already mentioned breast and                  to 2009 indicates a noticeable reduction from 109.8 to
prostate cancer are the major COD for women and                  102.4 SDR per 100 000 women at the ages of 65+.
men, respectively.                                               High numbers of cases follow a line from north-west
                                                                 to south-east of Europe, with SDR from equal and
Breast cancer seems to be closely linked to the
                                                                 higher than 130 per 100 000 for women in regions
genetic make-up, but also to the reproduction history
                                                                 from IE, UK, BE, NL, DK and DE south to HU and
of women, which may include hormone replacement
                                                                 RO, with highest SDR of 151.5 for DK.
therapy. The trend over time for the EU-27 from 2000

Map 7: Deaths due to breast cancer in women aged 65 years and more




(¹) MT, UK, CH 2005/2007; BE 2000/2002; Scotland, NUTS1 level; DK, SI, HR national level.
Source: Eurostat (online data code: hlth_cd_ysdr1)




10                                                                                     7/2012 — Statistics in focus
Prostate cancer is a significant cause of death for              south with higher levels in the northern parts: while
elderly men, with still uncertain aetiology. Age seems           regions of the Baltic countries, IS, NO and SE
to be the most relevant risk factor for developing               reported SDR of more than 270 per 100 000 men,
prostate cancer, which is increasingly found as part of          southern countries such as MT, MK and RO have
a multiple cause development towards death in an                 rates of less than 120 per 100 000. However, a closer
ageing population.                                               look at regional data indicates a more heterogeneous
                                                                 picture: Peak data of more than 270 per 100 000 men
At national level the trend over time indicates a clear
                                                                 were reported not only from FI, LT, LV, NO and SE
decline for the EU-27 from a SDR of 201.3 in the
                                                                 but also from PT and SI (plus FR overseas with the
year 2000 to 167.3 deaths per 100 000 men in 2009.
                                                                 highest SDR of 403.2 from Martinique) On the other
The only countries that reported reverse trends are
                                                                 hand, low figures came indeed from BG, EL, ES, IT,
CY, LV, LT, PL, RO, SI and MK.
                                                                 FR, MK, and RO, the lowest being for Sud-Vest
In view of the geographical distribution of SDR                  Oltenia (RO) with an SDR of 74.0.
across Europe there seems to be a slope from north to

Map 8: Deaths due to prostate cancer in men aged 65 years and more




(¹) MT, UK, CH 2005/2007; BE 2000/2002; Scotland, NUTS1 level; DK, SI, HR national level.
Source: Eurostat (online data code: hlth_cd_ysdr1)



.

          Statistics in focus — 7/2012                                                                              11
METHODOLOGICAL NOTES
The causes and groups of medical causes of death chosen              SDR A    = age standardised death rate for population in region
have been selected from the summary list of 65 causes
                                                                     A
compiled by Eurostat, which is based on the International
Statistical Classification of Diseases and Related Health            A
Problems (ICD) developed and maintained by the World Health            m x = age specific death rate at age x last birthday in
Organisation (WHO). Causes of death statistics are based on          population in region A
information derived from medical certificates; the medical
                                                                     S
certification of death is an obligation in all Member States. They      P x = the population exposed to the risk of death at age x last
target the underlying cause of death, in other words, the disease    birth day in the standard population
or injury which initiated the train of morbid events leading
directly to death. Although definitions are harmonised amongst       The indicator Male/Female ratio was also used to compare the
Member States, the statistics may not be fully comparable as         differences in mortality between men and women according to
classifications may vary when the cause of death is multiple or      country.
difficult to evaluate and because of different notification                     SDR _ M
procedures. Annual data are provided in absolute numbers, as         RMF =                   , where
crude death rates and as standardised death rates.                              SDR _ F
The spatial analysis scale used in this publication is the           RMF = male/female mortality rate
regional level. The data have been aggregated over the period        SDR _ M = male comparative rate
2006-2008, with the exception of some countries for which these
years data were missing: Malta, United Kingdom and                   SDR _ F = female comparative rate
Switzerland (2005-2007) and the Flemish part of Belgium (2000-       List of codes used for the Member States, accession,
2002). That aggregation was done in order to increase the            candidate and EFTA countries: Belgium (BE), Bulgaria (BG),
number of deaths, thereby reducing the number of regions with        Czech Republic (CZ), Denmark (DK), Germany (DE), Estonia
numbers too small for statistical processing.                        (EE), Greece (EL), Spain (ES), France (FR), Ireland (IE), Italy
The mortality indicator analysed in this "Statistics in Focus" is    (IT), Cyprus (CY), Latvia (LV), Lithuania (LT), Luxembourg (LU),
the standardised rate (SDR). The (age-) standardised death           Hungary (HU), Malta (MT), Netherlands (NL), Austria (AT),
rate is a weighted average of age-specific mortality rates. The      Poland (PL), Portugal (PT), Romania (RO), Slovenia (SI),
weighting factor is the age distribution of a standard reference     Slovakia (SK), Finland (FI), Sweden (SE), United Kingdom (UK),
population. The standard reference population used is the            Croatia (HR), former Yugoslav Republic of Macedonia (MK),
European standard population as defined by the WHO. As               Iceland (IS), Norway (NO), Switzerland (CH).
method for standardisation, the direct method is applied.            Acknowledgements
Standardised death rates are calculated for the age group 0-64       This publication was prepared in collaboration with the Core
('premature death'), 65 years and more and for the total of ages.    Group on Causes of Death statistics. The members of this Core
As most causes of death vary significantly with people's age and     Group are members of the National Statistical Authorities:
sex, the use of standardised death rates improves comparability      Monica Pace (Leader of the Core Group, ISTAT – Italy), Eric
over time and between countries.                                     Jougla (INSERM, France), Barbara Leitner (Statistik Austria),


        =∑
           ( m P ) , where
                x
                    A
                            x
                                S
                                        x
                                                                     Jan Kardaun (CBS, Netherlands), Torsten Schelhase
                                                                     (DESTATIS, Germany), Anne Gro Pedersen (SSB, Norway),
                                                                     Peter Ocko (UDZS, Slovakia) and Gleb Denissov (TAI, Estonia).
SDR A
          ∑ P
                        S
                    x               x


Further information
Eurostat Website: http://ec.europa.eu/eurostat
Data on ‘Health statistics’
http://epp.eurostat.ec.europa.eu/portal/page/portal/health/public_health/data_public_health/database
Select ‘Causes of death’
Further information about ‘Health statistics’
http://epp.eurostat.ec.europa.eu/portal/page/portal/health/introduction

Journalists can contact the media support service:
Bech Building, Office A4/125, L - 2920 Luxembourg
Tel. (352) 4301 33408 Fax (352) 4301 35349
E-mail: eurostat-mediasupport@ec.europa.eu

European Statistical Data Support:
With the members of the ‘European statistical system’, Eurostat has set up a network of support centres in nearly all
Member States and in some EFTA countries.
Their mission is to provide help and guidance to Internet users of European statistical data.
Contact details for this support network can be found on our Internet site:
http://ec.europa.eu/eurostat/

All Eurostat publications can be ordered via EU-Bookshop:
http://bookshop.europa.eu/


  Manuscript completed on: 20.01.2012
  Data extracted on: 22.09.2011
  ISSN 1977-0316
  Catalogue number:KS-SF-12-007-EN-N
  © European Union, 2012

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EUROSTAT Study on Circulatory diseases main causes of death for persons aged 65 and more in europe

  • 1. Population and social conditions Statistics in focus 7/2012 Authors: Hartmut BUCHOW, Elodie CAYOTTE and Lucian AGAFITEI Circulatory diseases - Main causes of death for persons aged 65 and more in Europe, 2009 For people of 65 years and older (65+), the main - Respiratory diseases – there is a heterogeneous causes of death are circulatory diseases, such as distribution for this complex group of causes of ischaemic heart diseases and cerebrovascular death diseases, followed by cancers. For those of less - Lung cancer – this disease has the highest than 65 years there is a difference by gender: for gender difference among the main causes of men circulatory diseases prevail, while women die death, as it accounts for four times as many almost twice as often from cancers than from deaths in men as in women circulatory diseases. - Colorectal cancer – there are no striking National and regional distributions of causes of regional or gender differences death in people of 65+ indicate the following: - Circulatory diseases – eastern European - Breast and prostate cancer – death rates show countries have the highest death rates a considerable decrease over time Causes of death (COD) among the over-65 age-group health programmes throughout Europe are largely are of increasing significance in European mortality aimed at the reduction of mortality before the age of statistics. A dramatic change in the nature of health 65 by preventive measures. They promote a healthier care over the past century has resulted in longer life life style with improved nutrition, lower tobacco and spans, but also greater prevalence of chronic illnesses. alcohol consumption, an increase in physical activity This has increased the demands on the health care and reduction of professional risks. In 2009 more than system, particularly for the treatment of ongoing 3.8 million deaths in the EU-27 occurred after the age illnesses and for long-term care. In addition, public of 65, 80.3 % of total deaths. Figure 1: Major causes of death for persons under 65 years and aged 65 and more – standardised death rates (SDR) per 100 000 inhabitants, EU-27, 2009 800 32 Males aged 65+ (left axis) 700 Females aged 65+ (left axis) 28 Males aged less than 65 (right axis) 600 24 Females aged less than 65 (right axis) 500 20 400 16 300 12 200 8 100 4 0 0 Ischaemic heart Cerebrovascular Diseases of the Lung cancer Colorectal cancer Breast Cancer Prostate cancer diseases diseases respiratory system (women only) (men only) Source: Eurostat (online data code: hlth_cd_asdr)
  • 2. The percentage of the population aged 65+ in the EU- Between 2000 and 2009 there was a reduction of 26% 27 is projected on average to increase from 16.0% in in EU-27 death rates resulting from ischaemic heart 2010 to 29.0 % in 2060 (see: The greying of the baby diseases and cerebrovascular diseases. Nevertheless, boomers. SIF: KS-SF-11-023). as shown in figure 1, for people of 65+ these circulatory diseases are still the main causes of death. It is therefore interesting to focus on the major causes For those of less than 65 years the situation is of death for that age group. different: while for men there is still a slight This publication addresses seven major COD for predominance of deaths by circulatory diseases (ratio persons aged 65+: 2 main disease groups of the 1.2), women die almost twice as often from lung, circulatory system, ischaemic heart diseases (such as colorectal and breast cancers than from circulatory heart attacks) and cerebrovascular diseases (such as diseases. strokes); the group of respiratory diseases, and 4 malignant neoplasms: lung cancer 1, colorectal, breast and prostate cancer. 1 Including neoplasm in larynx, trachea, bronchus and lung Gender differences in people of 65+ highest for lung cancer Going into gender differences for the seven COD Figure 2: Lung cancer for EU-27 by gender, SDR per studied, the main difference between men and women 100 000 inhabitants is for lung cancer. For ages 65+ the ratio of 450 40 Standardised Death Rates (SDR) for men to women is 400 35 5.0 in the year 2000, falling to 3.8 in 2009, see figure 350 30 2. It reflects a definite trend over time: while for 300 women of both age groups the EU-27 SDR goes up 25 250 from 8.3 to 10.2 (ages less than 65) and from 81.1 to 20 200 92.4 (ages 65+), respectively, the trend for men is the 15 reverse, from 33.1 to 27.3 for the younger and from 150 10 402.7 to 352.1 for the older age groups. 100 50 5 0 0 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 Males 65 years or over (left axis) Females 65 years or over (left axis) Males less than 65 years (right axis) Females less than 65 years (right axis) Source: Eurostat (online data code: hlth_cd_asdr) National differences in causes of death for the elderly in EU-27 For the EU-27 the SDR for people of 65+ is highest COD: here the third major COD is lung cancer and for ischaemic heart diseases with 568.8 per the fourth major COD is colorectal cancer (EE, LV). 100 000 inhabitants, followed by cerebrovascular PT is the only country where lung cancer is not diseases (397.4), respiratory diseases (326.0) and lung among the four major COD. cancer (201.2). The findings indicate a skew for circulatory diseases However, only 13 countries are strictly in line with towards eastern Europe. SDR of more than 900 per that pattern. For six countries cerebrovascular 100 000 inhabitants were reported for ischaemic heart diseases rank first among COD (BG, EL, LU, PT, SI diseases by CZ, EE, FI, LT, LV, MT, HU, SK, RO and MK). Four countries reported respiratory diseases and HR (with highest of more than 2 000 by LT and in first (BE, DK, ES and NL) and 10 other countries SK), and for cerebrovascular diseases by BG, LV, RO in second place (DE, EL, IE, FR, CY, LU, PT, UK, IS and MK. On the other hand only two countries have a and NO), while two countries do not report SDR of less than 300, FR for both disease groups and respiratory diseases at all as one of the four main CH for cerebrovascular diseases, see maps 1 and 2. 2 7/2012 — Statistics in focus
  • 3. Table 1: Major causes of death at national level for 65+ years, SDR per 100 000 inhabitants, 2009 Ischaemic heart Cerebrovascular Respiratory Lung cancer Colorectal Breast cancer Prostate cancer Country disease (total) diseases (total) diseases (total) (total) cancer (total) (females) (males) EU27 568.8 397.4 326.0 201.2 120.4 102.4 167.3 EU15 463.7 316.7 334.4 197.2 114.3 104.1 166.2 BE 480.7 340.0 541.6 244.8 121.9 124.1 190.1 BG 755.6 1 310.2 204.8 137.7 126.8 87.5 133.8 CZ 1 308.3 640.4 299.3 219.8 173.4 102.1 186.0 DK 453.2 315.1 524.1 290.0 157.8 151.8 267.6 DE 632.5 297.3 299.8 178.9 117.4 112.7 162.5 EE 1 535.9 485.2 129.2 188.1 133.9 92.2 301.6 IE 759.0 324.2 583.0 247.4 132.5 133.6 220.7 EL 379.3 611.2 416.1 211.6 85.6 103.7 141.5 ES 317.7 284.7 395.9 180.0 128.6 74.0 139.9 FR 235.8 208.0 209.8 165.2 107.9 103.5 169.3 IT 455.1 388.7 232.3 209.1 110.8 103.7 129.4 CY 458.4 301.4 311.7 144.5 64.2 88.4 143.3 LV 1 734.0 977.5 86.2 182.2 136.5 91.6 262.7 LT 2 250.2 895.8 197.9 178.1 142.3 93.1 241.1 LU 314.2 376.9 331.6 222.7 138.4 123.5 202.3 HU 1 523.9 666.4 273.3 273.9 207.1 117.0 171.0 MT 905.0 485.7 428.6 177.4 113.7 142.1 122.4 NL 306.1 266.9 426.3 267.8 135.8 119.5 207.8 AT 749.4 263.2 216.2 160.8 105.6 113.8 174.3 PL 660.3 516.4 287.3 260.9 139.0 82.9 177.5 PT 304.7 598.4 510.9 119.7 138.5 79.3 195.0 RO 1 317.7 1 276.5 260.9 169.5 114.7 88.8 122.9 SI 444.9 531.2 318.0 204.2 171.7 134.3 281.8 SK 2 072.4 715.0 338.1 188.7 181.9 100.9 186.2 FI 934.0 354.0 178.5 155.8 86.9 83.8 188.9 SE 639.0 325.7 239.1 155.0 113.7 84.0 271.3 UK 569.6 343.8 539.6 256.1 109.3 113.1 196.1 IS 666.1 302.6 339.1 238.6 116.5 115.5 259.3 NO 492.2 310.9 391.1 199.5 144.0 90.4 277.5 CH 506.3 233.7 215.4 161.1 96.1 106.5 205.9 HR 1 183.6 897.8 252.3 233.5 186.9 127.6 236.5 MK 564.8 1 442.9 240.4 186.6 113.4 103.1 138.2 BE: 2005; CH: 2007; FR, IT: 2008 Source: Eurostat (online data code: hlth_cd_asdr) Regional differences in EU-27 for causes of death (COD) in the elderly The following maps show differences for the was no apparent difference in the geographical aforementioned COD at regional level (NUTS 2 pattern, even though the ratio between men and regions) for the reference years 2006-2008. SDR for women may vary. men and women were combined into one map if there Cerebrovascular and ischaemic heart diseases: Highest COD rates in East- European regions For both groups of circulatory diseases the less than 250 per 100 000 inhabitants. The geographical distribution of SDR for people of 65+ is distributions for men and women are similar in similar, with highest rates for eastern European regions with the highest SDR, such as in regions of countries. BG and RO. However, only 18 regions reported rates of less than 250 deaths per 100 000 inhabitants for For cerebrovascular diseases highest SDR of more men, compared to 42 regions for women (data not than 1 000 per 100 000 inhabitants are found in shown; for details see Eurostat database). 16 regions of BG, LV, RO and MK, while 31 regions of AT, DE, ES, FR and CH reported lowest rates of Statistics in focus — 7/2012 3
  • 4. Map 1: Deaths due to cerebrovascular diseases in people aged 65 years and more (¹) MT, UK, CH 2005/2007; BE, 2000/2002; Scotland NUTS1 level; DK, SI, HR national level. Source: Eurostat (online data code: hlth_cd_ysdr1) For ischaemic heart diseases the highest SDR (more higher than 2 500 in LT, LV and SK. Lowest SDR of than 1 500 per 100 000 inhabitants) are reported from less than 250 per 100 000 inhabitants are found in 3 17 regions of the Baltic countries, CZ, HU, SK and regions of FR. On the other hand, for women only 10 RO. The regions with lowest rates (less than 250 per regions in HU, LT, LV, RO and SK have a SDR of 100 000 inhabitants) are in the south-west of Europe: more than 1 500 per 100 000 inhabitants, with highest 13 in FR, 2 in PT and one in ES. rate of 2 064 per 100 000 in LT. However, by contrast with the situation for men, 45 regions (11 from ES, 4 The difference in distribution of the highest and from EL, 25 from FR, 2 from PT and 3 from NL) lowest rates for men and women is more pronounced report a SDR of less than 250 per 100 000, with the than for cerebrovascular diseases: for men, 27 regions lowest for Guyane (FR, SDR 77.7). report a SDR of more than 1 500 per 100 000 inhabitants, with 4 regions having rates 4 7/2012 — Statistics in focus
  • 5. Map 2: Deaths due to ischaemic heart diseases in people aged 65 years and more (¹) MT, UK, CH 2005/2007; BE, 2000/2002; Scotland NUTS1 level; DK, SI, HR national level. Source: Eurostat (online data code: hlth_cd_ysdr1) Respiratory diseases: A heterogeneous regional distribution for a complex group of diseases For respiratory diseases, which include chronic with 1 137 per 100 000 inhabitants, followed by lower respiratory diseases or asthma as well as 10 UK regions with rates between 760 and 650 per infectious diseases such as influenza or pneumonia, 100 000. On the other hand 7 regions in EE, FI, FR there are some countries with a relatively high SDR and LV had a rate of 180 per 100 000 and below, for people of 65+ such as DK, IE, PT or UK, which with the very lowest of 117.6 for LV. can be clearly differentiated from those with lower The relation of SDR for men and women varies SDR such as the Baltic countries, FI and most parts from almost 1:1 in IS to ratios above 4.0 for the of FR. However, the regional distribution of death Baltic countries, the highest being for LT with 4.5. rates within the countries for respiratory diseases is The range differs also within the countries, from quite heterogeneous, but has a much smaller range 1.3 to 1.5 in the UK to 1.6-2.8 in FR, 1.7-2.7 in DE than for circulatory diseases: the highest SDR was or 2.2-3.8 in PL. reported by Regiao Autonoma de Madeira (PT) Statistics in focus — 7/2012 5
  • 6. Map 3: Deaths due to diseases of the respiratory system in people aged 65 years and more (¹) MT, UK, CH 2005/2007; BE 2000/2002; Scotland NUTS1 level; DK, HR, national level. Source: Eurostat (online data code: hlth_cd_ysdr1) The scattered picture for this complex group of may include differences in environmental causes of death may partly indicate differences in conditions including specific work conditions for reporting and coding practices, which may be less men, differences in public health campaigns that relevant for other diseases. In general death may not reach all of the elderly, such as certificates for the elderly are complicated due to vaccinations against influenza, or differences in several co-morbidities, with respiratory diseases reaching for a doctor in rural areas for pneumonia often playing an important role. Additional reasons complications in the elderly. 6 7/2012 — Statistics in focus
  • 7. Colorectal cancer: No striking regional or gender differences SDR for men and women were combined into one There seems to be a geographic slope from northern map as there is no obvious difference in the and central European countries to the south: highest geographical pattern nor in the ratio for men and SDR with more than 200 deaths per 100 000 can be women. noted in CZ, HU and SK. On the other hand SDR with less than 60 per 100 000 inhabitants were At present colorectal cancer ranks second for reported by FI, EL, and FR, with the lowest rate at malignant neoplasms affecting both women and men, 47.4 for Ipeiros (EL). Low figures for the following lung cancer. There is an appreciable Mediterranean regions of FR, the whole of EL, MT downward trend in most of the countries, with and part of IT contrast to higher rates for slightly more improvement for rectum and anus Mediterranean regions of ES, while low rates are also cancer, but it remains one of the major scourges for found in 3 regions of FI with less than 73 cases per the elderly. 100 000. Map 4: Deaths due to colorectal cancer in people aged 65 years and more (¹) MT, UK, CH 2005/2007; BE 2000/2002; Scotland, NUTS1 level; DK, SI, HR national level. Source: Eurostat (online data code: hlth_cd_ysdr1) Statistics in focus — 7/2012 7
  • 8. Lung cancer: A marked gender difference at national and regional level The fact that rates for lung cancer are much higher already been mentioned above. This is underlined for men than for women in the ages 65+ has by regional data as shown by the two maps. Map 5: Deaths due to larynx, trachea, bronchus and lung cancer in men aged 65 years and more (¹) MT, UK, CH 2005/2007; BE 2000/2002; Scotland NUTS1 level; DK, SI, HR national level. Source: Eurostat (online data code: hlth_cd_ysdr1) 8 7/2012 — Statistics in focus
  • 9. Map 6: Deaths due to larynx, trachea, bronchus and lung cancer in women aged 65 years and more (¹) MT, UK, CH 2005/2007; BE 2000/2002; Scotland NUTS1 level; DK, SI, HR national level. Source: Eurostat (online data code : hlth_cd_ysdr1) In 11 out of 32 European countries covered by the For people of 65+ maps 5 and 6 indicate highest SDR data the SDR for lung cancer is 6 or more times for men in eastern and south-western Europe plus higher for men of 65+ than for women, with MT northern UK on the one hand and an incline from having the highest ratio at 12.6. However, for those north-east to south-west for women on the other hand. less than 65 years almost all countries report a That difference in SDR for women is also reflected in shrinking gender difference: only 4 countries have the ratios men to women, which are highest with 9 ratios of 6 and higher, the highest being for LV at and more for regions in EL, ES, FR, IT and PT, but almost 12 times more for men than for women. also in LT, while ratios of 2 down to 1 are found in DE, IE, IS, NO, SE, and the UK. Statistics in focus — 7/2012 9
  • 10. Breast and Prostate Cancer: A noticeable decrease over time After the diseases already mentioned breast and to 2009 indicates a noticeable reduction from 109.8 to prostate cancer are the major COD for women and 102.4 SDR per 100 000 women at the ages of 65+. men, respectively. High numbers of cases follow a line from north-west to south-east of Europe, with SDR from equal and Breast cancer seems to be closely linked to the higher than 130 per 100 000 for women in regions genetic make-up, but also to the reproduction history from IE, UK, BE, NL, DK and DE south to HU and of women, which may include hormone replacement RO, with highest SDR of 151.5 for DK. therapy. The trend over time for the EU-27 from 2000 Map 7: Deaths due to breast cancer in women aged 65 years and more (¹) MT, UK, CH 2005/2007; BE 2000/2002; Scotland, NUTS1 level; DK, SI, HR national level. Source: Eurostat (online data code: hlth_cd_ysdr1) 10 7/2012 — Statistics in focus
  • 11. Prostate cancer is a significant cause of death for south with higher levels in the northern parts: while elderly men, with still uncertain aetiology. Age seems regions of the Baltic countries, IS, NO and SE to be the most relevant risk factor for developing reported SDR of more than 270 per 100 000 men, prostate cancer, which is increasingly found as part of southern countries such as MT, MK and RO have a multiple cause development towards death in an rates of less than 120 per 100 000. However, a closer ageing population. look at regional data indicates a more heterogeneous picture: Peak data of more than 270 per 100 000 men At national level the trend over time indicates a clear were reported not only from FI, LT, LV, NO and SE decline for the EU-27 from a SDR of 201.3 in the but also from PT and SI (plus FR overseas with the year 2000 to 167.3 deaths per 100 000 men in 2009. highest SDR of 403.2 from Martinique) On the other The only countries that reported reverse trends are hand, low figures came indeed from BG, EL, ES, IT, CY, LV, LT, PL, RO, SI and MK. FR, MK, and RO, the lowest being for Sud-Vest In view of the geographical distribution of SDR Oltenia (RO) with an SDR of 74.0. across Europe there seems to be a slope from north to Map 8: Deaths due to prostate cancer in men aged 65 years and more (¹) MT, UK, CH 2005/2007; BE 2000/2002; Scotland, NUTS1 level; DK, SI, HR national level. Source: Eurostat (online data code: hlth_cd_ysdr1) . Statistics in focus — 7/2012 11
  • 12. METHODOLOGICAL NOTES The causes and groups of medical causes of death chosen SDR A = age standardised death rate for population in region have been selected from the summary list of 65 causes A compiled by Eurostat, which is based on the International Statistical Classification of Diseases and Related Health A Problems (ICD) developed and maintained by the World Health m x = age specific death rate at age x last birthday in Organisation (WHO). Causes of death statistics are based on population in region A information derived from medical certificates; the medical S certification of death is an obligation in all Member States. They P x = the population exposed to the risk of death at age x last target the underlying cause of death, in other words, the disease birth day in the standard population or injury which initiated the train of morbid events leading directly to death. Although definitions are harmonised amongst The indicator Male/Female ratio was also used to compare the Member States, the statistics may not be fully comparable as differences in mortality between men and women according to classifications may vary when the cause of death is multiple or country. difficult to evaluate and because of different notification SDR _ M procedures. Annual data are provided in absolute numbers, as RMF = , where crude death rates and as standardised death rates. SDR _ F The spatial analysis scale used in this publication is the RMF = male/female mortality rate regional level. The data have been aggregated over the period SDR _ M = male comparative rate 2006-2008, with the exception of some countries for which these years data were missing: Malta, United Kingdom and SDR _ F = female comparative rate Switzerland (2005-2007) and the Flemish part of Belgium (2000- List of codes used for the Member States, accession, 2002). That aggregation was done in order to increase the candidate and EFTA countries: Belgium (BE), Bulgaria (BG), number of deaths, thereby reducing the number of regions with Czech Republic (CZ), Denmark (DK), Germany (DE), Estonia numbers too small for statistical processing. (EE), Greece (EL), Spain (ES), France (FR), Ireland (IE), Italy The mortality indicator analysed in this "Statistics in Focus" is (IT), Cyprus (CY), Latvia (LV), Lithuania (LT), Luxembourg (LU), the standardised rate (SDR). The (age-) standardised death Hungary (HU), Malta (MT), Netherlands (NL), Austria (AT), rate is a weighted average of age-specific mortality rates. The Poland (PL), Portugal (PT), Romania (RO), Slovenia (SI), weighting factor is the age distribution of a standard reference Slovakia (SK), Finland (FI), Sweden (SE), United Kingdom (UK), population. The standard reference population used is the Croatia (HR), former Yugoslav Republic of Macedonia (MK), European standard population as defined by the WHO. As Iceland (IS), Norway (NO), Switzerland (CH). method for standardisation, the direct method is applied. Acknowledgements Standardised death rates are calculated for the age group 0-64 This publication was prepared in collaboration with the Core ('premature death'), 65 years and more and for the total of ages. Group on Causes of Death statistics. The members of this Core As most causes of death vary significantly with people's age and Group are members of the National Statistical Authorities: sex, the use of standardised death rates improves comparability Monica Pace (Leader of the Core Group, ISTAT – Italy), Eric over time and between countries. Jougla (INSERM, France), Barbara Leitner (Statistik Austria), =∑ ( m P ) , where x A x S x Jan Kardaun (CBS, Netherlands), Torsten Schelhase (DESTATIS, Germany), Anne Gro Pedersen (SSB, Norway), Peter Ocko (UDZS, Slovakia) and Gleb Denissov (TAI, Estonia). SDR A ∑ P S x x Further information Eurostat Website: http://ec.europa.eu/eurostat Data on ‘Health statistics’ http://epp.eurostat.ec.europa.eu/portal/page/portal/health/public_health/data_public_health/database Select ‘Causes of death’ Further information about ‘Health statistics’ http://epp.eurostat.ec.europa.eu/portal/page/portal/health/introduction Journalists can contact the media support service: Bech Building, Office A4/125, L - 2920 Luxembourg Tel. (352) 4301 33408 Fax (352) 4301 35349 E-mail: eurostat-mediasupport@ec.europa.eu European Statistical Data Support: With the members of the ‘European statistical system’, Eurostat has set up a network of support centres in nearly all Member States and in some EFTA countries. Their mission is to provide help and guidance to Internet users of European statistical data. Contact details for this support network can be found on our Internet site: http://ec.europa.eu/eurostat/ All Eurostat publications can be ordered via EU-Bookshop: http://bookshop.europa.eu/ Manuscript completed on: 20.01.2012 Data extracted on: 22.09.2011 ISSN 1977-0316 Catalogue number:KS-SF-12-007-EN-N © European Union, 2012