DNB PEDIATRICS THEORY QUESTION BANK (UPDATED TILL JUNE 2012)

1. DNB PEDIATRICS
THEORY QUESTION BANK
(UPDATED TILL JUNE 2012)
DR KAUSIK SUR / Updated by DR. NOELLA PEREIRA JOHN
D.C.H, DNB D.C.H. (Mumbai)
ASSISTANT PROFESSOR
DEPARTMENT OF PEDIATRICS
VIVEKANANDA INSTITUTE OF MEDICAL SCIENCES
KOLKATA
e-mail- kausiksur@gmail.com
HOW TO INTERPRET THE QUESTIONS:
1. Questions are divided based on Chapters of Nelsons Textbook of Pediatrics
2. Questions contain two numbers at the end. Numbers within bracket indicates
the year. For example (97/1)- 97 means year 1997
1 means June (2 means December)
Thus (06/1) means June 2006
3. Number at the end of the question(not within bracket) indicates marks

2. 1 GROWTH AND DEVELOPMENT
1. Approach to a child with Delayed Speech (02/1) 15
2. Discuss the causes and approach to a Preschool child with Developmental
Regression (02/1) 25
3. Growth Monitoring (98/1) 15
4. What are the developmental disorders in preschool years? Discuss the
management (97/1) 15
5. Velocity and cross-sectional standards as applied to Human Growth (95/2)
15
6. Discuss the basis for use of Growth Standards. What should be taken as a
reasonable approach for India (94/2) 25
7. Principles of Growth and Development (00/1) 15
8. Importance of Bone age assessment in children 15
9. Growth Factors (99/1) 15
10. Sexual Maturity Rating in female adolescents (95/2) 15
11. Describe the events of sexual development in relation to physical growth.
Name the most important regulatory factors (94) 25
12. Gessel Developmental schedule (93/1) 15
13. Define Growth, Development, Velocity of growth mean, median, percentiles.
Enumerate causes of retarded growth. Briefly outline a schedule for
investigation of such a case (92/2) 25
14. Factors affecting Development of children (92) 15
15. SMR (03/2)
16. What is SMR? Discuss the secular trend in Children (05/2) 5+5
17. How would you assess sexual maturity of a female adolescent (06) 10
18. Factors affecting Adolescent health and development (06) 10
19. Write the height velocity curves of girls and boys from birth to adolescence,
describe the principles and factors governing the growth and development in
children (06) 10
20. Approach to a child with short stature (06/1) (07/2) 10
21. Bone age assessment and its usefulness (07/2) 10
22. Growth and development in second year of life in children (07/1) 10
23. Outline the basic principles of sleep hygiene for children and adolescents
(09/1) 10 (12/1) 5+5
24. Describe: (09/2) 5+5
a) Factors affecting child development
b) Developmental screening tests available and suitable for use in Indian
children.
25. Developmental milestones in first two years of life. (10/1) 10
26. Outline the fine motor milestones along with their normal age of achievement
in sequence attained between birth and 5 years of age. (10/2) 10
27. Discuss the evolution and characteristics of WHO growth charts. Discuss
their implications on the magnitude of malnutrition in Indian setting. (11/1)
3+4+3
28. Enumerate the available methods and indications for determination of bone

3. age in children and adolescents. Outline the differential diagnosis of a child
with short stature on the basis of bone age. (11/1) 3+3+4
29. Describe Tanner’s Sexual Maturity Rating (pubertal staging) in boys based
on a) Genitalia and b) Pubic hair development. (11/2) 5+5
30. Describe in detail the physical growth and development in all domains from
birth till completion of first year. (11/2) 5+5
31. What is developmental delay? Describe different tools used for screening of
developmental delay. (11/2) 3+7
32. Define growth velocity. Draw a typical height velocity curve from birth to
puberty for boys and girls. Discuss the utility of determining growth velocity.
(12/1) 2+4+4
33. What is developmental screening? Enumerate common developmental
screening test. What issues they identify in a child? (12/1) 2+4+4
2 PSYCHOLOGIC DISORDERS
PSYCHOSOMATIC ILLNESS
1. Management of Conversion reactions (98/1) 15
VEGETATIVE DISORDER
1. Sleep Disorders in children (99/2) 10
2. Encopresis (99/2) 15
3. What is Vegetative Disorder (05) 5
4. What is vegetative disorder? Discuss management of a child with injuries
(05) 5+5
5. Rumination (06/1) 5
6. Pica (07/1) 5
HABIT DISORDER
1. Habit Disorders in children (07/1) 10
MOOD DISORDER
1. Childhood Depression (06) 10
DISRUPTIVE BEHAVIORAL DISORDERS
1. Common Behavioral problems in children (97/2) 15
PERVASIVE DEVELOPMENTAL DISORDER AND CHILDHOOD
PSYCHOSIS
1. Autism (03/2) 15
2. Define autism. Outline its etiology. Outline the clinical markers of autism
and its prognosis. (04/2) 2+3+3+2
3. Discuss the management of a child with schizophrenia (04/2) 5
4. Autistic spectrum disorder (07/2) 10

4. 5. Autistic Disorder (07/1) 10
6. Etiology, clinical manifestations and treatment of Autistic Disorder
(06/1) 10
7. Discuss the management of a child with Schizophrenia (05) 5
8. Describe the etiology, clinical manifestations and management of autistic
spectrum disorders in children. (09/2) 2+3+5
9. Discuss briefly the diagnostic features and management of Pervasive
Developmental Disorders/ autistic spectrum disorders. (11/2) 4+6
10. Enumerate various pervasive developmental disorders and autism
spectrum disorders. Outline one core feature of each of them. (12/1) 5+5
NEURODEVELOPMENTAL DYSFUNCTION IN THE SCHOOL AGED CHILD
1. Attention Deficit Disorders (97/1) (95/2) (00/1) 15
2. ADHD (03/1) 15
3. Describe clinical manifestations, diagnosis and management of ADHA (06)
10
MISCELLANEOUS
1. Juvenile Delinquency (06/1) 5
3 SOCIAL ISSUES, CHILDREN WITH SPECIAL HEALTH NEEDS
FAILURE TO THRIVE
1. Causes of Failure to Thrive in infancy (96/2) 15
2. Approach to a child with Failure To Thrive (96/1) 14
3. Define failure to thrive. Outline a diagnostic approach for a child with failure
to thrive. (04/2) 2+8
4. Non organic failure to thrive (07/1) 10
5. Define failure to thrive. Give its etiology, classification, clinical features and
management. (09/2) 1+2+2+2+3
6. Define failure to thrive and tabulate its causes. Outline the approach to
manage a child with failure to thrive. (10/2) 2+3+5
ADOPTION
1. Adoption (03/2)
CHILD ABUSE
1. Define child abuse. List the etiology of child abuse in India. Outline strategies
for prevention. (04/2)
2. Discuss Child maltreatment. What are the factors related with child abuse
(05) 5+5

5. 3. Define Child Abuse. Describe clinical manifestations of Child Abuse. Discuss
some useful investigations in a suspected case of Child Abuse (06) 10
4. Management of the sex abused child (95/2) 15
5. Define child abuse. Describe in brief the factors responsible for child abuse.
Outline management of a child who is suspected of being abused. (11/1)
2+3+5
6. Define child abuse and neglect. Discuss various clinical manifestations,
diagnostic work up and management of physical abuse. (11/2) 2+3+2+3
7. Write short notes on : (09/2) 5+5
a. Female infanticide
b. Karyotyping
MENTAL RETARDATION
1. Preventable and treatable causes of Mental retardation (96/2) 10
2. Various physical features that are likely to be associated with specific
syndromes of mental retardation (95/2) 10
3. Enumerate the causes of mental retardation in children. Give an outline of
management of a child with mental retardation. (10/1) 4+6
4 NUTRITION
PEM
1. Immunological changes that take place in PEM (98/2) 10
2. Biochemical changes in PEM (96/2) 10
3. Discuss the influences of malnutrition on mental functions in relation to its
onset, severity and type of functional losses with supportive advances (93/1)
25
4. Prevention of hypocalcaemia in PEM (93/1) 15
5. Age independent Anthropometric criteria for assessment of PEM (06) 5
6. Management of a 4 year old child with grade 4 PEM (07/2) 10
7. Outline the initial management ( in first 48 hours) of a 2 year old severely
malnourished child (weight 5.5kg) who is cold to touch and has edema and
poor peripheral pulses. (08/1) 10
8. Discuss biochemical and metabolic derangements in a child with severe
malnutrition. Discuss factors associated with high mortality in severe PEM.
(08/2) 10
9. Outline the 10 steps of management of severe malnutrition, as per WHO
guidelines, in appropriate sequence. (10/2) 10
10. Define ‘Severe Acute Malnutrition (SAM)’. Outline the tools for its diagnosis
in the community and discuss their merits/ demerits. (12/1) 2+4+4

6. VIT A
1. Hazards and virtues of Vitamin A in pediatric practice (96/2) 10
2. Vitamin A supplementation (07/1) 5
3. Enumerate functions of vitamin A in human body. Tabulate the WHO
classification of vitamin A defiency. Outline the treatment schedule for
managing Xerophthalmia in children. (10/2) 2+3+5
VIT B
1. Discuss the etiopathogenesis, clinical features, diagnosis and management of
cobalamine deficiency. (12/1) 2+3+1+4
VIT D
1. Functions of vitamin D (98/2) 10
2. Renal Rickets (97/2) 15
3. Vitamin D Resistant Rickets (96/2) 12
4. Resistant Rickets 15
5. Outline the metabolism and function of Vitamin D in human body. Describe
in detail the etiology and pathological changes in rickets (99/2) 25
6. Clinical manifestations of Rickets (93/2) 10
7. What are the causes of non nutritional rickets. How will you manage such a
child. (04/2) 3+7
8. Classify the various causes of rickets and outline how to differentiate them
(05) 5+5
9. Diagnostic approach to a child with resistant rickets (06) 10
10. Resistant Rickets (06/1) 10
11. Discuss calcium and vitamin D metabolism. Outline an approach to a case of
Resistant Rickets (07/1) 10
12. Discuss the pathophysiological basis of clinical and radiological
manifestations of nutritional rickets. (09/1) 10
13. Describe vitamin D metabolism. Describe diagnostic approach to a 3 year old
child with rickets who has shown no response to treatment with 6 lac I.U. of
vitamin D. (09/2) 4+6
14. Outline the clinical features, radiological changes, diagnosis and treatment of
nutritional vitamin D deficiency rickets (10/2) 2+2+2+4
15. Write in brief the role of vitamin D in health and disease in children. Outline
the management of Vitamin D deficiency disorder. (12/1) 6+4
VIT C
1. Scurvy- radiological changes. How are they produced? What is the role of
Blood Level of Vit C in the diagnosis (05) 10
VIT E
1. Enumerate the functions and therapeutic uses of Vit E (98/1) 15
2. Vitamin E and its role in human nutrition (92/2) 15
VITAMINS
1. Hypervitaminosis in Children (96/1) 12

7. COPPER
1. What are the dietary sources of copper? What are the diseases associated with
abnormal copper metabolism? Describe investigations, clinical features and
treatment of any one of them. (09/2) 1+2+7
ZINC
1. Effects of Zinc supplementation in persistent diarrhea (98/2) 10
2. Role of Zinc in health and diseases of children (97/1) 10
3. Relevance of Zinc in human nutrition (92) 15
4. Give dietary requirements of Zinc in children and discuss its role in
childhood immunity and infections (07/1) 10
5. Write short notes on: Zinc supplementation – when and how? (11/2) 5
MAGNESIUM
1. Sources, deficiency state and uses of magnesium in children. (10/1) 3+3+4
MILK
1. Bioactive factors in Human Milk (98/1) 15
2. Differences in the composition of Milk secreted by mothers delivering Term
and Preterm babies (96/2) 10
3. Discuss the physiology of Breast Milk secretion and advantages of breast
feeding with special reference to metabolic aspects. What are the causes of
lactation failure (99/1) 25
4. Anti-infective properties of Human milk (95/2) 10
5. Enlist the problems of breastfeeding and outline the management of the
same(05) 4+6
6. Explain the occurrence of low prevalence of Hypoglycemia and iron
deficiency anemia in breast fed infants (05) 10
7. How would you assess the adequacy of breast milk for a 2 months old baby.
Enumerate 4 features of good attachment of a baby to the breast. What can
be the problems with poor attachment (06) 10
8. Compare the composition of human milk with cow’s milk. Outline the
difference in the milk composition of a mother with a premature neonate
from that of a term neonate. Describe the immunological factors present in
human milk. (08/2) 10
IODINE
1. Prevention of Iodine deficiency (95/1) 15
FLUORINE
1. Prevention of Fluoride toxicity (95/1) 15
OBESITY
1. Approach to a child with obesity (99/1) 15

8. 2. Define obesity in childhood. List the causes of obesity in children. Outline
strategies for its prevention. (04/2) 2+3+5
3. What is Obesity? Discuss the management in children (05) 3+7
4. Approach to a child with Obesity (06/1) (07/2) 10
5. Outline the diagnostic measures and clinical manifestations of obesity. Enlist
the differential diagnosis of childhood obesity. (09/2) 2+3+5
6. Define syndrome X. Outline the diagnostic criteria and laboratory work up
for obese children. (10/1) 2+3+5
7. Define obesity. List causes of obesity. Discuss approach to a child with
obesity. (11/1) 2+3+5
MISCELLANEOUS
1. Metabolism of fat absorption along with role of MCT in nutrition (03/1) 15
2. What is Complimentary Feeding? Discuss the feeding problems in first year
of life (05) 5+5
3. How would you assess the nutritional status of a child whose age is not
known (05) 10
4. Describe the attributes of complimentary feeding. What is the safe age of
introduction of complementary feeding in your opinion – Justify. Describe
some foods appropriate for complimentary feeding. (08/2) 10
5. Daily nutritional requirements as recommended Daily Allowance (RDA) in
infants and children. (10/1) 5+5
6. Define complimentary feeding. Outline the attributes of complimentary
foods. Enumerate the recommendations on complimentary feeding, as per
the National guidelines on Infant and Young Child Feeding (IYCF) (10/2)
2+2+6
7. Name the micronutrients required for various body functions. Discuss briefly
their dietary sources and the effects of deficiency of mineral micronutrients
(trace elements). (11/2) 3+2+5
8. Outline the nutritional support of a critically ill child. List the complications
during management of such a child. (12/1) 7+3
5 PATHOPHYSIOLOGY OF BODY FLUIDS AND FLUID
THERAPY ACUTELY ILL CHULD
SHOCK
1. How do you classify Shock in children? Write its aetiopathogenesis and
management (06) 10
2. Discuss the classification and causes of shock in children (97/1) 15
3. Management of Cardiogenic shock (96/1) 12
4. Define Shock. Describe the pathophysiology and management of septic shock
in children (94/2) 25 (04/2) 5+5

9. 5. Shock-pathogenesis of different types and pathological changes in different
organs (03/1) 25
6. Discuss the management of an infant with Shock (00/1) 25
7. Discuss the pathophysiology of cardiogenic shock. How are the various
hemodynamic parameters affected in cardiogenic shock? Discuss steps in
monitoring and treatment of cardiogenic shock. (08/2) 10
8. Define fluid refractory shock. Describe the management strategy for a 2 year
old child with fluid refractory shock. (10/1) 3+7
9. Define septic shock. Describe the etiopathogenesis and clinical features in a
15 month old child presenting with septic shock. (11/2) 2+4+4
POTASSIUM
1. List the causes of Hypokalemia. Discuss the clinical features, laboratory
diagnosis and management of Hypokalemia (06) 10
2. Define hypokalemia. Enlist its causes and outline clinical features and its
treatment (09/2) 1+3+2+4
SODIUM
1. List the causes of Hyponatremia. Discuss the clinical features, lab diagnosis
and management of Hyponatremia (05) 3+4+3
2. Enumerate common causes of Hyponatremia (06) 5
3. Define hypernatremia. Describe the pathophysiological changes and steps of
management of hypernatremia. (10/1) 2+4+4
4. Define hyponatremia. Enumerate the etiology of hyponatremia. Describe the
management of hypovolemic hyponatremia. (10/2) 2+3+5
5. Define hypernatremia. Enumerate the etiology of hypernatremia. Describe
the management of hypernatremic dehydration. (11/1) 3+4+3
ACID-BASE BALANCE
1. Anion Gap (98/2) (00/1) 10
2. Describe briefly how the acid-base balance of body is maintained in health
(98/1) 25
3. Physiological compensatory mechanisms during Metabolic Acidosis (97/1)
15
4. Define pH and base excess. Discuss briefly regulation of Acid-base
homeostasis and management of Respiratory Acidosis (93/1) 15
5. Pathophysiology of Acid-base disorders (03/1) 15
6. Anion Gap (03/2) 15
7. Define anion gap and its utility. Outline the major causes of metabolic
acidosis in children. Outline the treatment of renal tubular acidosis. (04/2)
2+4+4
8. Outline the normal mechanism of acid-base regulation in children. What is
anion-gap? Describe the causes and management of a child with metabolic
acidosis (07/2) 10

10. 9. List the causes of metabolic alkalosis. Describe the pathophysiology, clinical
features and treatment. (08/2) 10
10. Classify metabolic acidosis based on anion gap. Mention the various causes
of lactic acidosis. Describe the approach to diagnosis of inborn error of
metabolism in an infant. (08/2) 10
11. Classify and enlist the causes of metabolic alkalosis. Outline the treatment
modalities. (10/1) 3+3+4
12. Define anion gap. Enlist causes of increased anion gap acidosis and discuss its
management in brief. (11/1) 2+3+5
DEHYDRATION
1. Steps in management of patient with Hypernatremic Dehydration (06) 10
2. Management of Hypernatremic Dehydration (02/1) 15
3. Management of Acute Diarrhea in children (98/1) 15
4. Pathogenesis and Management of Hypernatremic Dehydration (97/2) 15
5. One year old infant with AGE develops Abdominal Distension. Discuss the
differential diagnosis (97/1) 10
6. Why children are more vulnerable to develop dehydration (96/2) 10
7. Hypernatremic Dehydration (03/1) 15
8. Hyponatremic Dehydration (03/2) 15
9. A one year old infant weighing 5.5kg presents with Acute Dysentery and
severe dehydration. Discuss its complete management (06/1) 10
10. A one year old baby weighing 5.5kg comes in severe dehydration. Discuss
complete management (07/2) 10
11. Discuss causes, predisposing factors and pathophysiology of Hypernatremic
dehydration in young children (07/1) 10
12. Describe the pathophysiology of hyponatremic dehydration. Briefly discuss
the management of a child with serum sodium of 110 meq/liter presenting
with moderate dehydration and seizures. (08/2) 10
6 ACUTELY ILL CHILD
DROWNING
1. Near drowning in children (06) 10
2. An 18 month old child was brought to you after he fell upside down in a tub
filled with water. Briefly describe the possible injuries and preventive
strategies to avoid similar situation in future. (08/1) 10
3. Describe the pathogenetic mechanism of injury in near drowning. Discuss the
steps of initial resuscitation and subsequent hospital management. (08/2) 10
4. Discuss the pathophysiology of submersion injury. A 4 year old boy was
rescued 10 min back from a pond and rushed to the hospital emergency.
Mention the basic principles of management. (12/1) 5+5

11. PAIN
1. Pathogenesis and management of pain in children (06) 10
2. Pain management in infants and children (98/1) 15
3. Enumerate various sedatives and analgesics recommended for children
undergoing painful procedures. Describe their main action, indication in
pediatric practice and important side – effects in a tabular format. (08/1) 10
4. Write short notes: (12/1) 5+5
a)Non-pharmacological methods in pain management.
b) Drug therapy in neonatal pain management.
BURN
1. How is the degree of Burns classified? Write the initial fluid therapy for a
one year old child weighing 10 kg with 20% 2ND degree burns (06) 10
2. Provide classification of burns injury. Describe the clinical manifestation of
electrical burns. Outline emergency management of a child with 20% burns.
(11/2) 2+3+5
COLD INJURIES
1. Cold Injury (07/1) 10
BRAIN DEATH
1. Brain Death (98/1) (99/2) 15
2. Define Brain Death. Write age specific criteria for Brain Death in children.
(11/2) 2+8
P.A.L.S.
1. Draw an algorithm for managing pulseless ventricular tachycardia and
ventricular fibrillation. (08/1) 10
2. How will you assess that a 10 year old child who has fallen unconscious in
front of you required basic life support. What are the steps for basic life
support to such a child (as per American Heart Association Guidelines for
CPR) (09/1) 3+7
MECHANICAL VENTILATION
1. Describe the various pressures which are used or varied during mechanical
ventilation. What is ‘Cycling’ and ‘Control’ in mechanical ventilator? Describe
the differences in pressure controlled and volume controlled ventilation.
Illustrate with suitable indication use of these forms of ventilation. (08/2) 10
7 GENETICS
1. Genetic counseling of a case of Down Syndrome (99/1) 15
2. Early stimulation in Down syndrome (92/2) 15
3. Prenatal diagnosis of Down syndrome and Duchenne Muscular Dystrophy
15

12. 4. Gene Therapy in Children (06/1) 10
5. Gene therapy (07/1) 5
6. Enumerate and describe the structural abnormalities of autosomes. Illustrate
with suitable examples. (08/1) 10
7. What are trisomies? What are predisposing factors? Discuss clinical features
of 3 common trisomies seen in clinical practice? (08/1) 10
8. Describe the symbols used in pedigree chart. Draw pedigree charts over 4
generations depicting a) X – linked dominant disease b) X – linked recessive
disease.
9. Briefly discuss the principles of genetic counseling. Outline the counseling of
a family with a child with Down’s syndrome. (04/2) 5+5
10. A couple has a child with Down Syndrome. Outline the principles of genetic
counseling and antenatal management for the subsequent pregnancy.(09/1)10
11. Write a short note: Karyotyping (09/2) 5
12. What are mutations? Describe their consequences. (10/1) 5+5
13. Discuss the genotypic and phenotypic features of Turner’s syndrome (11/1)
4+6
14. What are mitochondrial genes? How are they transmitted? Briefly discuss
diseases transmitted by them? (11/2) 2+2+6
8 METABOLIC DISEASES
1. Screening tests for Inborn Errors Of Metabolism (96/2) 10
2. Metachromatic Leukodystrophy (96/1) 12
3. Homocysteinuria (94/2) 15
4. Discuss the diet plan in various metabolic disorders (99/1) 15
5. Write briefly about glucose metabolism in body. Describe briefly glycogen
storage disorders. (04/2) 4+6
6. Laboratory Screening tests for metabolic Disorders (06/1) 10
7. Provide a diagrammatic representation of urea cycle. Indicate and name
related disorders of urea cycle metabolism at each step. (08/1) 10
8. Discuss the enzymes replacement therapy and substrate reduction strategies
in management of metabolic disease. (08/2) 10
9. Enlist the inborn errors of metabolism (IEM) with their associated peculiar
odor. Provide the investigative approach for an infant with suspected IEM.
Describe the treatment of phenylketonuria. (09/2) 4+4+2
10. Define hypoglycemia. Describe clinical features and management of
hypoglycemia in newborn and children. (11/2) 1+4+5

13. 9 NEONATOLOGY
RESPIRATORY DISTRESS
1. Describe the surgical causes of Respiratory difficulty in newborn (02/1)
25
2. Surfactant therapy (98/2) 10
3. Meconium Aspiration Syndrome(97/2) 15
4. BPD (97/1) 15
5. Surfactant therapy for HMD 15
6. Tests for pulmonary maturity and surfactant therapy for RDS (94/2) 15
7. Discuss RDS with special reference to surfactant therapy (98/2) 15
8. Discuss the pathogenesis and management of MAS (00/1) 25
9. Pathophysiology of RDS of newborn (94) 15
10. HMD- pathophysiology and management (03/1) 25
11. List the causes of respiratory distress in preterms. Outline the principles of
surfactant therapy in preterms. Outline the manifestations of oxygen therapy
in newborns. (04/2) 2+4+4
12. What is the etiopathogenesis of PPHN of Newborn. Outline the diagnosis and
management (05) 3+3+4
13. Describe in brief PPHN (or PFC) with regard to Pathology,
pathophysiology, Diagnosis and management (94/2) 25
14. What is the sequence of events leading to the first breath after delivery?
What is the significance of establishment of Functional Residual Capacity?
(06) 10
15. Etiology, pathogenesis and management of a neonate with RDS (06/1) 10
16. PPHN (06/1) 10
17. Briefly discuss normal fetal development of Surfactant. List the uses of
Surfactant in newborn (07/2) 10
18. Discuss the diagnosis and management of PPHN (07/2)
19. Enumerate causes of persistent pulmonary hypertension in neonates and
discuss its pathophysiology. (08/1) 10
20. Discuss the approach to diagnosis of Persistent Pulmonary Hypertension of
Newborn (PPHN). Outline the available modalities of management,
highlighting their key features in a tabular format. (10/2) 4+6
21. Discuss the pathophysiology of hyaline membrane disease in premature
newborns. (10/2) 10
22. Describe the pathophysiology of hyaline membrane disease (HMD) in
newborns. Outline important available strategies to prevent HMD. (11/1) 5+5
SURGICAL
1. Enumerate congenital anomalies presenting as severe respiratory distress in
a newborn. Describe the pre-operative and post operative care of a neonate
with tracheo – esophageal fistula. (10/1) 4+3+3
2. Enumerate causes of persistent vomiting in a 4 week old child. Describe
clinical features and management of hypertrophic pyloric stenosis. (12/1)
3+3+4

14. RESUCITATION
1. How do you assign APGAR score to a neonate. In which 5 conditions will you
get a low score without associated hypoxia? What are fallacies of APGAR
score. (06) 10
2. A term baby is apnoeic. What information of the perinatal events you would
like to know? What are the initial steps of management in the labor room?
What are the possible complications in the next 48 hours? (08/2) 10
3. Describe the changes taking place in circulation at birth and their
implications in neonatal resuscitation. (09/1) 5+5
4. Enumerate the newer recommendations of neonatal resuscitation by
American Academy of Pediatrics 2010 guidelines. Comment on the level of
evidence for each of the changes. (12/1) 6+4
BIRTH ASPHYXIA
1. Perinatal asphyxia- clinical features and management (02/1) 15
2. HIE (97/2) 15
3. Clinical and laboratory correlates of neuromotor outcome in Birth Asphyxia
(97/1) 10
4. Discuss the etiopathology and management of birth asphyxia (96/2) 25
5. HIE in newborn (95/1) 10
6. Discuss briefly pathophysiology and recent modalities of management of HIE
(99/2) 25
7. HIE (93/1) (92/2) 15
8. Prognosis of Birth Asphyxia (93/1) 10
9. What are the etiological causes of Fetal Hypoxia? Write pathophysiology of
Fetal Hypoxia. Describe stages of HIE (06) 10
10. Pathophysiology of Hypoxic Brain injury in neonate (06/1) 10
11. Discuss the pathophysiology of hypoxic Ischemic Encephalopathy (HIE) in
neonates. (09/1) 10
NEONATAL SEIZURES
1. Etiopathogenesis of neonatal seizures (02/1) 15
2. Management of Resistant Neonatal Seizure (03/2) 15
3. Classify neonatal seizures. Outline their etiology and provide a brief clinical
description. Provide general principles of management of a seizure in
neonate. (12/1) 2+2+3+3
IVH
1. IVH (3/1) 15
2. Outline the risk factors, pathophysiology and principles of management of
intraventricular hemorrhage in preterm neonates. (10/2) 3+3+4

15. 3. Discuss the pathogenesis of intracranial hemorrhage in newborn infants.
Outline the possible promoters and protectors for occurrence of subsequent
white matter disease. (12/1) 6+2+2
PAIN
1. Discuss the impact of pain on a preterm neonate. Identify common procedures
associated with pain in a newborn. Describe the strategies for pain
management in a newborn. (08/2) 10
2. Write short notes: (12/1) 5+5
a)Non-pharmacological methods in pain management.
b) Drug therapy in neonatal pain management.
NEONATAL HYPOGLYCEMIA
1. Management of neonatal hypoglycemia (98/2) (92/2) 10
2. Define Hypoglycemia in newborn. List its causes. Describe stepwise
treatment if hypoglycemia in a newborn (06) 10
TEMPERATURE
1. Thermal regulation in newborn (98/2) 10
2. Hypothermia in the newborn (97/1) 15
3. Thermoregulation peculiarities in newborn (94/2) 15
4. Prevention of Hypothermia in the newborn (98/2) 15
5. Physiological and biochemical consequences of Hypothermia in Neonate3
(99/1) 15
6. Thermal balance in Neonates (03/2) 15
7. Discuss management of Neonatal Hypothermia (06) 5
8. Write the components, pre-requisites and benefits of Kangaroo Mother care.
(08/2) 10 , (11/2) 5+2+3
9. Discuss the principles of care of the skin in neonates. Outline the role of
touch and massage therapy in newborn infants. (10/2) 4+3+3
ANTENATAL DIAGNOSIS
1. Antenatal Diagnosis (98/2) 10
2. Discuss the methods of detection of congenital malformations in the fetus and
their prevention (95/1) 25
3. Intrauterine Diagnosis (93/2) 10
4. Amniocentesis in prenatal diagnosis (92) 15
5. Methods to diagnose fetal disorder. Fetal medical therapy (05) 5+5
6. List various methods for Fetal diagnosis and assessment along with
indications (06) 5
7. Prenatal Diagnosis and Fetal therapy (06/1) 10
8. Medical management of Fetal Problems (07/2) 10
9. Treatment and prevention of fetal diseases (07/1) 10
10. What are the methods of diagnosis of fetal disorders? Describe the fetal
medical and surgical therapeutic options for various fetal disorders. (09/2) 10

16. FETUS
1. Describe in detail tests for antepartum and intrapartum monitoring of fetal
distress (06) 5
2. Fetal monitoring (06) 10
3. Discuss the complications in the fetus and newborn of a mother with diabetes
during pregnancy. (08/1) 10
RENAL
1. Kidney functions in neonate (98/2) (99/2) 10
INFECTIONS
1. Infection control in neonatal intensive care (98/2) 10
2. Congenital toxoplasmosis (97/2) 15
3. Infants of HIV seropositive mothers (95/1) 15
4. Infants of HBV seropositive mothers (95/1) 15
5. Early diagnosis of Neonatal Septicemia (94/2) 15
6. Newer modalities in the management of neonatal sepsis (99/2) 15
7. Screening tests for neonatal sepsis 15
8. Prevention of Mother to Child transmission of Hep B 15
9. Rapid diagnostic tests in a suspected case of Neonatal Septicemia (95/2)
10
10. Sepsis Screen in neonates (06/1) 10
11. Antibiotic treatment of Neonatal Meningitis (93/2) 10
12. Candidiasis in Neonates (06) 10
13. Adjuvant therapy in Neonatal sepsis (06) 10
14. Differential Diagnosis of Neonatal sepsis (07/1) 10
15. Discuss various adjunct therapies in neonatal sepsis. (08/1) 10
16. Discuss the risk factors for vertical transmission of HIV infection and
methods to prevent parent to child transmission of HIV. (09/1) 4+6
17. Discuss the predisposing factors, causative agents, methods of diagnosis and
treatment of neonatal osteomyelitis. (09/1) 4+6
18. A 3 day old home delivered boy (Weight 1450g, Gestation 36 wk) is brought
to you with abnormal body movements and not accepting feeds. The child is
cold to touch and capillary filling time is 5 sec. outline the immediate, short –
term and long term management of this child. (09/1) 4+6
19. Enumerate the clinical features that indicate presence of a possible intra
-uterine infection in a neonate. Describe the interpretation of TORCH
screen. (09/2) 6+4
20. Clinical features, investigations and prevention of Congenital Rubella
Syndrome. (10/1) 3+3+4
21. Outline the clinical presentation, diagnosis and management of a neonate
with intrauterine CMV infection. (11/1) 3+4+3
22. Discuss the available strategies for prevention of mother to child
transmission of HIV. (12/1) 10

17. SFD
1. Immune status of SFD babies (98/1) 15
2. Factors associated with IUGR (93/1) 10
3. Enumerate the etiology of fetal or intrauterine growth retardation (IUGR).
Describe the screening and diagnosis of IUGR. (11/2) 3+4+3
APNEA OF PREMATURITY
1. Pathophysiology of Apnea Of Prematurity (97/2) 15
2. A 10 day old preterm neonate has recurrent cessation of breathing lasting for
more than 20 seconds with bradycardia. Classify and enumerate causes for
this condition. Discuss in brief the management of this condition. (12/1) 4+6
RETINOPATHY OF PREMATURITY
1. ROP (07/1) 10
OSTEOPENIA OF PREMATURITY
1. Osteopenia of prematurity (06) 10
NEONATAL JAUNDICE
1. A 3 week old infant brought to the hospital with moderate jaundice. Discuss
the Diagnosis (97/2) 10
2. Kernicterus (97/1) 15
3. Pathogenesis of kernickterus (96/2) 10
4. Discuss the Bilirubin metabolism and list the causes and approach to
Diagnosis of Hyperbilirubinemia in a neonate (00/1) 25
5. Discuss reasons for Physiological Jaundice in a Newborn. Define and list
causes of pathological jaundice in a newborn. Discuss clinical manifestations
(acute and chronic)of kernickterus (06) 10
6. Outline the normal metabolism of bilirubin. Outline the principle of
phototherapy for treatment of neonatal jaundice. List factors that influence
efficacy of phototherapy. (08/1) 10 (09/1),(10/2) 4+3+3
7. Critically describe the role of various treatment modalities for treating
neonatal unconjugated hyperbilirubinemia. (11/2) 10
NEC
1. NEC (97/2) 15
2. Pathogenesis of NEC (97/1) (92) 15
3. Etiology and pathology of NEC 15
4. Etiology of NEC, staging and management. (04/2) 10
5. Discuss management of NEC (06) 5
6. Discuss the clinical features, diagnosis and management of neonatal
necrotizing enterocolitis. (09/1) 3+7
7. Discuss the pathophysiology, classification and diagnostic features of
necrotizing enterocolitis. (10/2) 4+3+3

18. 8. A 6 day old preterm neonate presents with abdominal distension, feed
intolerance, vomiting and blood in stools. Discuss the differential diagnosis,
diagnostic approach and principles of initial stabilization. (12/1) 4+3+3
NEONATAL HYPOTHYROIDISM
1. Clinical features of Cretinism in newborn babies (97/1) 10
2. Desccribe in brief the etiology, clinical features, diagnostic investigations and
management of congenital hypothyroidism. (11/1) 2+2+3+3
PRETERM
1. Enumerate the socio-demographic factors associate with Low birth weight
babies. Discuss the clinical problems of Preterm babies (96/1) 25
2. Pharmacotherapy in prematurity clinical decisions- salient features (03/1)
15
3. Management of Patent Ductus Asteriosus (PDA) in preterm neonates(10/1)10
HAEMATOLOGY
1. Management of Neonatal Thrombocytopenic Purpura (00/1) 15
2. Hemorrhagic Disease of The Newborn (95/2) 15
3. Causes of Anemia in the Newborn (93/1) 10
4. Discuss aetiopathogenesis, diagnosis and management of a Bleeding Neonate
(06/2) 10
5. Anemia in newborn infant (07/1) 10
6. Define polycythemia in a newborn. What are the factors predisposing to it?
Describe the impact of polycythemia on various systems and their clinical
presentation. Describe the management of polycythemia in newborn. (08/2)
10
7. Outline the classification, clinical manifestations, laboratory findings and
differential diagnosis of vitamin K deficiency bleeding. (12/1) 3+3+2+2
FLUID THERAPY
1. Fluid therapy in special situations in neonates (06/1) 10
HIGH RISK INFANT
1. Discuss the basic elements of the ‘At Risk’ concept with regard to their
advantages and disadvantages and fallacies if any as they relate to health
care of mothers and children (95/2) 25
2. Define ‘High risk infant’. Discuss the long term management of such infants
with emphasis on detection and early intervention of infants with
developmental disabilities (95/1) 25
MISCELLANEOUS
1. Role of O2 free radicals in the pathogenesis of neonatal disorders (96/2) 10
2. Bullous skin eruptions in newborn babies (95/2) 15
3. Endocrine problems that can be diagnosed on the first day of life (95/1) 10
4. Prenatal steroid therapy (99/2) 15

19. 5. Steps in Neonatal Resuscitation 15
6. Fetal circulation and changes at birth (00/1) 15
7. Placental dysfunction syndrome (95/2) 15
8. Scheme for identifying High Risk Fetuses (92/2) 15
9. Hydrops Fetalis (03/1) 15
10. Non immune hydrops fetalis (03/2) 15, (07/1) 10
11. Fetal Therapy (03/2) 15
12. List the principles of community care of LBW infants. Define Kangaroo
Mother care. Outline its advantages and disadvantages. (04/2) 4+2+4
13. Outline the handicaps in enteral feeding of LBW newborns. Briefly discuss
the feeding strategies for LBW babies. (04/2) 3+4+4
14. What is Hydrops fetalis. Discuss etiology of Non immune hydrops fetalis.
What is the management of a case of Non immune hydrops fetalis (05)
2+5+3
15. Biology and role of cytokines in Newborn Infants (06/1) 10
16. ECMO (06/1) 10
17. CPAP (06/2) 10
18. Organization and levels of Newborn care (06/1) 10
19. Complications of infants born to diabetic mothers (07/2) 10
20. Steroid in neonatal care (07/1) 5
21. Enumerate common peripheral nerve injuries in neonates. Describe their
clinical characteristics and outline the management. (09/1) 2+3+5
22. Discuss the proposed hypothesis on ‘fetal origins of adult disease’ and its
implications on burden of diseases. (11/1) 5+5
10 SPECIAL HEALTH PROBLEMS DURING ADOLESCENCE
1. Juvenile Delinquency (02/1) 15
2. Etiological factors in Juvenile Delinquency (98/2) 15
3. Role of health education to Adolescents (98/2) 10
4. Discuss the special health problems of Adolescents (98/1) 25
5. Health education of adolescent girls 15
6. Adolescent Violence (03/1) 15
7. Health problems of adolescents(03/2) 15
8. What are the common problems in Adolescence (05) 5
9. Problems of adolescence (07/2) 10
10. What are the common problems in adolescence (05) 5
11. Discuss briefly Adolescent Health Problems (07/2) 10
11 IMMUNOLOGY
1. Prenatal Diagnosis of Primary Immunodeficiency diseases (94/2) 10
2. Graft versus host disease (99/1) 15
3. Indications for various organ and tissue transplants in Pediatric practice and
common considerations in selection of donors (95/2) 10

20. 4. Laboratory investigation of a child suspected to have T-cell immunity
Disorder (92) 15
5. Approach to a child with suspected immune dysfunction (06/1) 10
6. numerate functions of the Phagocytes and briefly describe defects of their
functions. (09/1) 4+6
7. Enlist the humoral immunodeficiency disorders. Outline the diagnostic
approach and treatment. (10/1) 4+6
8. Outline the characteristic features of primary immunodeficiency. Write in
detail about pathogenesis and clinical features of chronic granulomatous
disease. (11/1) 4+3+3
12 ALLERGIC DISORDERS
1. Pathogenesis and management of anaphylaxis (97/1) 15
2. Mechanism, manifestations and management of anaphylaxis (92) 15
3. Allergic Rhinitis (07/1) 5
4. Enumerate the chemical mediators of allergic reactions and describe the
important actions of histamine. (08/1) 10
5. Clinical features, differential diagnosis and treatment of atopic dermatitis in
infants. (10/1) 3+3+4
6. What is atopic dermatitis? Describe the clinical features and differential
diagnosis of atopic dermatitis. (11/2) 2+5+3
7. What is atopic dermatitis? Describe clinical features, differential diagnosis
and treatment of atopic dermatitis. (12/1) 1+3+3+3
13 NEPHROLOGY
GLOMERULAR FILTRATION
1. Outline the development of glomerular filtration. Outline the methods for
evaluating GFR in children. (08/1) 10
2. List the children to be selected for assessing renal function. Briefly discuss
the tests used to assess the renal function in children. (04) 3+7
RENAL REPLACEMENT THERAPY
1. Renal replacement therapy in ESRD (00/1) 15
2. Peritoneal dialysis (03/1) 15
3. Renal replacement therapy (06/1) 10
4. Discuss renal replacement therapy (07/1) 10
RTA
1. Classify types of RTA and their management principles (02/1) 15
2. Diagnosis and management of RTA (92/2) 15
PROTEINURIA
1. Persistent asymptomatic proteinuria (98/2) (07/1) 10

21. 2. Proteinuria (96/2) 15
HEMATURIA
1. Diagnosis and management of recurrent Hematuria (96/1) 12
2. A 3 year old child was brought for Hematuria. Discuss the differential
diagnosis and management (94/2) 25
3. Evaluation of a child with Hematuria 15
4. Outline the differential diagnosis of an abdominal lump with hematuria in a
3 year old child. Describe its investigations and treatment. (09/2) 3+3+4
5. Write the common causes and differential diagnosis of gross symptomatic
hematuria. Provide an algorithm for its laboratory and radiological
evaluation. (10/2) 2+2+6
6. Outline the causes of red coloured urine. Provide an approach for evaluation
of a child with red colored urine. (11/1) 3+7
7. Discuss the pathology, clinical manifestations, diagnosis and treatment of
infantile polycystic kidney. (11/2) 2+2+3+3
PSGN
1. Discuss the pathogenesis, clinical features and management of acute PSGN
2. Enumerate the complications of acute post – streptococcal
glomerulonephritis. Describe their management in brief. (10/2) 3+7
NEPHROTIC SYNDROME
1. Enumerate the principles of management of Idiopathic Nephrotic syndrome
(98/2) 10
2. Pathophysiology of Nephrotic Syndrome (96/2) 10
3. What factors will you consider in deciding the prognosis of a child with
Nephrotic syndrome (95/1) 15
4. Relapse in Nephrotic Syndrome (94) 15
5. Frequently relapsing steroid resistant Nephrotic Syndrome (03/2) 15
6. What factors help you to clinically decide non-minimal nature of Nephrotic
Syndrome? Enumerate the steps to test urine for albumin using heat
methods (05) 10
7. Histopathological changes in RPGN 15
8. Write the management of a 6 year old child with Nephrotic syndrome who is
frequently relapsing. Enumerate complications that can occur (06/2) 10
9. Management of steroid dependent nephrotic syndrome (07/2) 10
10. Describe the diagnostic approach and management in a case of frequently
relapsing and steroid dependent nephritic syndrome. (09/2) 4+6
11. Management of steroid resistant nephrotic syndrome. (10/1) 10
12. Define steroid dependent and frequently relapsing nephrotic syndrome.
Describe management of an 8 year old child with frequent relapsing
nephrotic syndrome. (11/1) 2+2+6

22. RENAL FAILURE
1. Biochemical and endocrinal changes in CRF
2. What are the causes of ARF in children? How will you investigate such a
case? Discuss management. (97/1) 25
3. Describe the pathogenesis of CRF and outline important principles in the
management of such a case (95/2) 25
4. What are the causes of acute renal failure in a 4 year old child. How will you
investigate such a case. Discuss the management of acute renal failure.
(04/2) 4+3+3
5. Outline the etiopathogenesis of ARF in children. Discuss briefly the
management (05) 5+5
6. List the causes of renal failure in a 3 month old child. Discuss the clinical
features, laboratory diagnosis and treatment of acute renal failure in
children. Discuss the indications of renal biopsy in children (06) 10
7. Discuss the etiology of cortical necrosis in newborns and older children,
separately. State the most important clinical manifestations of cortical injury
and factors governing prognosis. (08/1) 10
8. Discuss the role of recombinant human erythropoietin therapy (indication,
dose, aim, precaution, benefits and complications) in management of chronic
renal failure. List reasons of resistance to such therapy. (08/1) 10
9. What is acute renal failure? List the common causes leading to it. Tabulate
the laboratory indices used to differentiate pre-renal and intrinsic acute
renal failure. Outline the medical management of acute renal failure. (08/1)
10
10. Define renal osteodystrophy. Enumerate its clinical features and outline the
management. (09/2) 2+3+5
HUS
1. HUS- etiopathogenesis and diagnosis (98/1) 15
2. Diagnostic features of HUS (93/2) 15
TUBULAR DISORDERS
1. Nephrogenic Diabetes Incipidas (98/2) 15
2. Pathogenesis, clinical features and management of Distal Renal Tubular
disorder (07/2) 10
3. Define anion gap and its utility. Outline the major causes of metabolic
acidosis in children. Outline the treatment of renal tubular acidosis. (04/2)
2+4+4

23. 14 RHEUMATIC DISEASES
KAWASAKI DISEASE
1. Phases and complications of Kawasaki’s disease (06) 10
2. Kawasaki Syndrome (00/1) 15
3. Discuss the presentation, diagnostic criteria for Kawasaki Disease. What is
the management strategy? What are the complications? (08/1) 10
4. Discuss the pathogenesis, differential diagnosis and echocardiography
findings in Kawasaki Disease (KD). How is the classical KD different from
Atypical KD? (09/1) 6+4
5. Describe clinical manifestations of classical and atypical Kawasaki disease.
Provide algorithmic approach to a suspected case of Kawasaki disease.
Enumerate various treatment modalities. (11/1) 4+4+2
JRA
1. Classification and features of JRA (96/2) 14
2. What are the clinical manifestations of juvenile rheumatoid arthritis. Discuss
the differential diagnosis and management. (04/2) 3+3+4
3. Write the current classification used in JRA. Outline the management plan
for JRA (06) 10
4. Tabulate differentiating features of various types of juvenile rheumatoid
arthritis. (08/1) 10
5. Tabulate the classification of Juvenile Idiopathic arthritis and state
principles of its treatment. (10/2) 4+6
6. Outline the diagnostic criteria of juvenile rheumatoid arthritis. Tabulate the
differentiating features of various types of JRA. Outline a scheme of
investigation for a child with suspected JRA. (11/1) 3+4+3
7. Tabulate the differentiating clinical features and the diagnostic approach of
Juvenile Idiopathic Arthritis (JIA). Outline the principles of management of
polyarticular JIA. (12/1) 4+3+3
H S PURPURA
1. Discuss briefly clinical presentation and management of H S Purpura (07/1)
10
2. Describe the diagnostic approach and management of a six year old child
presenting with purpuric rash and pedal edema following an episode of acute
diarrhoea. (11/2) 4+6
MISCELLANEOUS
1. Classify vasculitis based on size of involved vessels and give examples of each
category. Describe etiology, clinical features and management of Takayasu’s
arteritis. (09/2) 5+5

24. 15 INFECTIOUS DISEASES
PUO
1. Discuss definition, etiology and approach to investigation of PUO (07/1) 10
2. Outline the approach to management of a 2 month old infant having fever
without focus. (09/1) 10
3. Enumerate the common causes of pyrexia of unknown origin in a 5 year old
child. Discuss diagnostic approach to fever with rash. (11/2) 4+6
HIV
1. Prevention of HIV infection during childhood (02/1) 15
2. HIV and Pediatrics (98/2) 10
3. Post exposure HIV prophylaxis (03/2) 15
4. An HIV positive mother has been admitted in labour. What will you do to
prevent transmission of infection to the baby (05) 10
5. Factors involved in perinatal transmission of HIV infection and the various
preventive measures (06) 10
6. Prevention of Childhood AIDS (07/2) 10
7. Clinical Presentations requiring screening for HIV (07/1) 5
8. HIV and TB (07/1) 5
9. Outline clinical and immunological criteria for starting anti-retroviral
treatment (ART) in a HIV infected child. How will you monitor a child
initiated on ART? (09/2) 6+4
10. Enlist the common opportunistic infections in HIV infected children.
Describe the clinical features, diagnosis and management of herpes simplex
infection in HIV infected children (11/2) 3+2+2+3
11. Enumerate opportunistic infections in HIV infected children. How will you
treat and prevent pneumocystis jiroveci infection. (12/1) 5+3+2
TB
1. Diagnosis and management of a child with resistant TB (02/1) 15
2. Short course chemotherapy for TB (98/2) 10
3. Prevention and early detection of TB (96/2) 15
4. CNS changes in Tubercular meningitis(Pathological only) 15
5. Discuss the pathogenesis, clinical symptomatology and diagnosis of NeuroTB
(06) 10
6. How do you perform and interpret Mantoux Test. Enumerate 3 conditions
each in which you can get a false positive and a false negative result. (06)
10
7. Newer diagnostic modalities for TB (06) 10
8. Describe clinical manifestations, diagnosis and management of Neuro –
tuberculosis. (11/2) 3+4+3
ENTERIC FEVER
1. Interpretation of Widal test in immunized children (98/2) 10
2. Nontyphoidal salmonellosis (95/2) 15

25. 3. Management of typhoid fever (95/2) 15
4. Treatment of typhoid fever (93/1) 10
5. Define multidrug resistant (MDR) salmonella typhi (MDR – ST) and
nalidixic acid resistant salmonella typhi (NARST). Discuss the mechanism of
development of drug resistance for salmonella typhi. (08/1) 10
6. Detail the various complications of enteric fever and briefly outline the
specific management. (08/2) 10
DENGUE FEVER
1. Pathogenesis of bleeding and shock in Dengue fever (98/2) 10
2. Discuss the management of Dengue Shock Syndrome (97/1) 10
3. Dengue Fever (03/2) 15
4. Define DHF and DSS and outline the treatment of DSS (05) 10
5. Diagnosis and management of DHF and DSS (06/1) 10
6. Outline the WHO criteria for diagnosis of dengue hemorrhagic fever. Draw
an algorithm for volume replacement for a child with DHF and > 20%
increase in hematocrit. (09/1) (3+7)
7. Define DHF and DSS. How does DHF differ from dengue fever with
hemorrhage? Describe treatment of DSS. (09/2) 2+2+1+5
8. Classify severity of dengue hemorrhagic fever. Write in brief the
management of dengue shock syndrome. (11/1) 4+6
E COLI
1. Classification of E coli and pathogenesis of Invasive Diarrhoea (95/1) 15
2. Discuss the pathogenesis of E. coli diarrhea (94/2) 15
POLIO AND AFP
1. AFP Surveillance (99/2) 15
2. Approach to a child with AFP and components of AFP surveillance (00/1)
15
3. AFP- Definition, Differential Diagnosis in details, how help in polio
eradication (03/2) 25
4. Discuss the differential diagnosis and management of acute flaccid paralysis
in a 2 year old child. (04/2) 5+5
5. What is AFP? Discuss the differential diagnosis and management of a child
with AFP. Discuss AFP surveillance (05) 2+3+2+3
6. Define criteria for declaring a country Polio free. What is the present status
of wild polio virus transmission and strategies being used for its control in
India? Elaborate on AFP surveillance (06) 5+5
7. Pulse Polio programme (02/1) (98/1) 15
8. Define AFP. Enlist the causes and investigations of a case of AFP (06) 10

26. 9. What is acute flaccid paralysis? Describe the differential diagnosis and
management of a child with flaccid paralysis. Describe AFP surveillance.
(09/2) 2+2+4+2
MALARIA
1. Define drug resistant malaria, what are the different types of drug resistance
as per WHO criteria. Discuss the various management strategies of Drug
resistant Malaria 25
2. Management of Cerebral Malaria 15
3. Drug resistant Malaria (03/1) 15
4. What are management guidelines of malaria under the national programme.
How will you manage a case of cerebral malaria. (04/2) 4+6
5. Enumerate manifestations of Severe Malaria and their management (06/2)
10
6. A 4 year old girl presents with history of fever for 2 days associated with
severe anemia, black colored urine and splenomegaly. Discuss the
management of this patient. (08/2) 10
7. Describe clinical manifestations of cerebral malaria. Enlist the differential
diagnosis and investations required. Write management of a case of cerebral
malaria in high endemic area. (09/1) (2+3+5)
8. Define complicated malaria. Describe the management strategies of
complicated malaria. (09/2) 3+7
9. Provide algorithms for case-detection and treatment for a child with fever,
suspected to have malaria, as per National Vector – Borne Disease Control
Program: (10/2) 5+5
a) In an area where microscopy results are available within 24 hours; and
b) In an area where microscopy results are not available within 24 hours
9. Write short notes on: Laboratory diagnosis of malaria (11/2) 5
HEPATITIS B
1. Viral markers of Hepatitis B 15
2. Immunological markers of Hepatitis B 15
3. Hepatitis B infection in children (03/1) 15
4. A 3 year old child is brought with a history of jaundice since 2 months. She
gives a history of blood transfusion at 18 months of age. Her HBSAg is
positive. Discuss briefly other viral markers of HepB infection which will
help in monitoring and treatment of child. Discuss the management of
fulminant hepatic failure. Add a note on Liver Transplantation. (06) 10
MEASLES
1. Diagnosis and treatment of SSPE (95/2) 10
PLAGUE
1. Management of Plague (95/2) 10

27. GROUP A STREPTOCOCCUS
1. Management of acute Rheumatic Fever (93/2) 10
CYSTICERCOSIS
1. Current management of Neurocysticercosis (92) 15
MENINGOCOCCUS
1. Discuss prevention and prophylaxis against meningococcal infection (05)
5+5
2. Prophylaxis of Meningococcaemia (06/1) 10
SYPHILIS
1. Radiological features and confirmatory laboratory tests for congenital
syphilis (07/1) 10
MISCELLANEOUS
1. Laboratory diagnosis of Viral diseases
2. Brain CT findings in a case of Congenital toxoplasmosis and cysticercosis
(94) 15
3. Nosocomial Infections (06) 10
4. Comment on clinical features, diagnosis and treatment of Swine flu in
children. (09/2) 2+3+5
5. A seven year old girl is admitted with pain and swelling of right knee and left
ankle joint of two weeks duration. Enumerate the likely causes. Discuss the
differential diagnosis highlighting important pointers in history, examination
and investigations. (11/2) 2+8
6. Describe the etiology, mode of transmission, clinical features and
management of viral hemorrhagic fever in children. (12/1) 2+2+3+3
16 DIGESTIVE SYSTEM
GIT
1. What is H.Pylori Bacillus? How is it associated with chronic abdominal pain
(98/2) 10
2. Pathogenesis of Celiac Disease (97/2) 15
3. Pathogenesis of Persistent Diarrhea of infancy (96/2) 10
4. Diagnosis of carbohydrate intolerance (95/1) 15
5. Gastro esophageal Riflux (94/2) 15
6. Persistent Diarrhea (99/1) 15
7. Chronic Diarrhea in Infancy (00/1) 15
8. Immunological features associated with cow milk allergy 15
9. Enumerate the etiology and discuss the pathogenesis of acute diarrhoea.
Describe the approach to management of a child with acute watery
diarrhoea. (04/2) 3+3+4

28. 10. Write management of Persistent Diarrhea (06) 5
11. Approach and management of a child with Persistent Diarrhea (06) 10
12. Diagnosis and management of a child with Celiac Disease (06/1) 10
13. Tracheoesophageal Fistula and Esophageal atresia (06/1) 10
14. Aetiopathogenesis and diagnosis of celiac disease (07/2) 10
15. Define malabsorption. Enlist the generalized and specific malabsorption
states. Discuss the investigative plan for a child with generalized
malabsorption. (08/1) 10
16. Define Recurrent Abdominal Pain (RAP) and list the diagnostic features of
functional RAP. Suggest a plan for investigations and managing a 10 year old
girl with RAP (09/1) 4+6
17. Etiology, pathogenesis, clinical features and management of acute
pancreatitis in children. (10/1) 2+2+2+4
18. Describe the etiology, pathogenesis, diagnosis and treatment of antibiotic
associated diarrhoea. (10/2) 1+2+3+4
19. Enlist the functions of pancreas. Outline the pancreatic function tests and
their implications in pediatric practice. (10/2) 4+6
20. Outline the etiopathogenesis of chronic diarrhea and provide a scheme of
investigating for a child with chronic diarrhea. (11/1) 5+5
21. Describe the types of diarrhoea with examples. Discuss their
pathophysiological mechanisms. (11/2) 5+5
22. A 9 month old child with acute watery diarrhea develops seizures and altered
sensorium. Discuss the differential diagnosis of CNS symptoms. Provide
diagnostic algorithm for managing this child. (12/1) 6+4
23. Define gastro – esophageal reflux disease (GERD). Describe its clinical
features, diagnosis and treatment. (12/1) 1+3+3+3
PREBIOTICS & PROBIOTICS
1. Outline the benefits of bacterial colonization of the intestine and the
disorders they can produce. (04/2) 5+5
2. Define probiotics. Explain their physiological mechanism of action.
Opportunities and threats associated with the use of probiotics in pediatric
practice. (08/2) 10
3. Define probiotics and prebiotics and enumerate their essential
characteristics. Outline the effects of probiotic in various gastrointestinal
disorders. (09/1) (5+5)
4. Discuss the management of acute diarrhea with particular reference to low
osmolarity ORS, zinc, probiotics and antibiotics. (10/2) 3+2+3+2
5. Define probiotics and prebiotics. Outline their important properties and
mechanisms of action. Enlist four most important indications of their clinical
use in Pediatric clinical practices. (11/1) 4+4+2
HEPATOBILIARY
1. Pathophysiology of Portal Hypertension (98/2) 10

29. 2. Discuss the causes, clinical features and management of portal hypertension
in children. (04/2) 3+3+4
3. Laboratory Finding of Fulminant Hepatic Failure (98/2) 10
4. Diagnosis and management of Acute Viral Hepatitis (96/2) 12
5. Cholestatic Jaundice 15
6. Biliary Atresia (95) 15
7. Describe Biochemical and Pathological changes in various organs in Hepatic
Encephalopathy. How will you manage a case (93/2) 10
8. Hepatic Encephalopathy- pathophysiology and management (03/2) 25
9. List the causes of infantile cholestasis. Provide an algorithm for the diagnosis
of infantile cholestasis. (04/2) 3+7
10. Persistent Jaundice in neonates (06) 10
11. Clinical approach, investigations and management of a neonate with
Cholestatic jaundice (06/1) 10
12. Discuss the management of Fulminant Hepatic Failure. Add a note on Liver
Transplantation (06)
13. A 6 week old child is brought with a history of jaundice since 3 weeks of age,
high colored urine with staining of napkins and pale colored stools. Discuss
the laboratory diagnosis of this condition. What is the differential diagnosis
and treatment of this condition (06) 10
14. Diagrammatically represent the portal venous system and the sites of Porto-
systemic vascular anastomosis in portal hypertension. Discuss the types,
cause and pathophysiology of portal hypertension (07/1) 10
15. Define Fulminant Hepatic Failure and outline the staging of severity of
Hepatic encephalopathy. Discuss the steps in its management. (09/1) 4+6
16. Outline the differential diagnosis of tender hepatomegaly. Describe the
management of liver abscess. (10/1) 5+5
17. Outline the management of an 8 year old child with acute liver cell failure
and hepatic encephalopathy. (10/2) 10
18. Write in brief the etiopathogenesis, clinical manifestations of Wilson’s
disease. Outline the desired investigation helpful in making a diagnosis of
Wilson’s disease. (11/1) 3+3+4
19. Define neonatal cholestasis. Outline clinical features and scheme for
evaluation of a neonate with cholestasis. (11/1) 2+3+5
20. Describe clinical, laboratory and radiologic evaluation of possible liver
dysfunction in children. (11/2) 3+4+3
21. Enumerate the causes and discuss the types, pathogenesis and evaluation of
ascites in children. (11/2) 2+2+3+3
MISCELLANEOUS
1. Hematemesis (94) 15
2. Differential Diagnosis of Ascites in children (93/1) 10
3. A 5 yr old child brought to the emergency- H/o 2 bouts of massive
hematemesis. On examination the child is pale and BP is 90/60. Discuss the
emergency room management of this child. After the child is stabilized what

30. laboratory diagnosis would you do in this child. What is the Differential
Diagnosis and treatment of this condition (05) 10
4. Management of Acute Upper GI Bleeding (06) 10
5. Discuss the management of acute upper gastrointestinal bleeding in a 5 year
old child. (08/1) 10
6. Define hematemesis, malena and hematochezia. A 3 years old child presents
with sudden onset vomiting of blood. Describe the approach to this child
(including history and examination). Outline the steps of management. (08/2)
10
17 RESPIRATORY SYSTEM
CLINICAL EXAMINATION
1. Enumerate 4 adventitious sounds that can be heard during examination of
respiratory system. At what anatomical level are they produced? In which
conditions are they produced. (06) 10
2. Outline the pulmonary function testing in children with emphasis on
performance and interpretation of spirometry.
3. Briefly discuss the non invasive estimation of gas exchange in children.(04) 10
BRONCHIAL ASTHMA
1. Describe the pathogenesis of Bronchial Asthma. Give an outline for
prevention and treatment of recurrent episodes (02/1) 25
2. Treatment of Bronchial asthma (96/2)
3. Discuss briefly the recent advances in the management of Bronchial Asthma
(99/1) 15
4. Use of Nebulizers in Pediatric practice (95/2) 10
5. Aerosol therapy in children (95/2) 15
6. Management of Acute Severe Asthma (92/2) 15
7. Management of Status Asthmaticus in a 3 yr old (03/1) 25
8. Discuss the pathophysiology of asthma. Outline the role of investigations in
bronchial asthma. (04/2) 6+4
9. Classify Asthma in children. Outline the management of asthma and
approach to a case of Status Asthmaticus (05) 3+4+3
10. Discuss the steps in evaluation of chronic asthma is children. Classify and
discuss the drugs used in the treatment of chronic asthma. Write briefly on
targeted delivery systems in treatment of asthma (06) 10
11. Pathophysiology and management of Asthma in children (06/1) 10
12. Management of a 3 year old child with recurrent attacks of wheezing (07/2)
10
13. Outline the stepwise approach for managing infants and young children (<=
5 year of age) with chronic asthma (09/1) 10

31. 14. How do you grade the severity of childhood asthma? Describe its stepwise
treatment according to the severity. Compare and contrast oral therapy to
inhaled therapy for asthma. (09/2) 3+3+4
15. Enlist the drugs used for management of chronic asthma. Explain the
pharmacological basis of their use. (10/1) 3+7
16. Discuss the lung function abnormalities in severe asthma. What is the role of
lung function evaluation in management of asthma in children. (10/2) 6+4
17. Discuss categorization of chronic childhood asthma. Discuss step – wise
management of chronic asthma in children . (11/2) 3+7
PNEUMONIA
1. Discuss briefly the Differential diagnosis and management of a case of
Persistent Pneumonia in a 3 month old infant (99/2) 15
2. Treatment of Staphylococcal pneumonia (93/1) 10
3. Define interstitial lung disease (ILD). Enlist pediatric ILDs. Write brief
description of lymphocytic interstitial pneumonitis (LIP). Outline the
treatment options for ILD in children.(08/1) 10
4. Discuss differential diagnosis and management of a child with recurrent
pneumonia. (11/2) 4+6
BRONCHIOLITIS
1. Course and prognosis of Acute Bronchiolitis (98/2) 10
2. Define acute bronchiolitis. Describe its etiopathogenesis and characteristics
features. Outline the essential steps in management of bronchiolitis. (10/2)
2+2+2+4
STRIDOR
1. A 2 year old child presents to the hospital with fever and Stridor of 12 hour
duration. Discuss the diagnosis (97/1) 10
2. Management of Acute Stridor in a Preschool child (93/1) 15
3. List the common causes of stridor in children. How will you diagnose and
manage a case of stridor. (04/2) 3+4+3
4. 1 year old child is brought with a history of sudden onset of respiratory
distress and stridor of 2 days duration. What is the differential diagnosis?
Discuss the steps in the management of Viral Croup (06/2) 10
5. Clinical Evaluation and management of a child with stridor (06/1) 10
6. Discuss the differential diagnosis and management of a 3 year old girl with
history of cough and cold, presenting with onset of noisy breathing, barking
cough, hoarse voice and respiratory distress. (08/1) 10
7. Differential diagnosis and management of acute stridor in a 2 years old child.
(10/1) 3+7
8. A 2 year old boy presents with fever, change of voice and stridor for 2 days.
Outline the differential diagnosis and management options. (12/1) 6+4

32. PHYSIOLOGY
1. Respiratory system defense mechanisms (93/2) 15
2. Define ventilation/ perfusion ratio. (11/1) 2
Outline Va/Q changes in:-
a) Pneumonia 2
b) Obstructive lung disease 2
c) ARDS 2
d) Pulmonary thromboembolism 2
TONSILITIS
1. Management of Acute Tonsillitis in children (98/1) 15
CONGENITAL MALFORMATIONS
1. Describe the congenital malformations of the lungs. Discuss the diagnosis and
management of these malformations (96/2) 25
2. Detail the causes for localized emphysema of the lung. Describe the
presentation and management of congenital lobar emphysema. (08/1) 10
RESPIRATORY FAILURE
1. Clinical and physiological features necessary to diagnose respiratory failure
in children (94/2) 15
2. How will you define acute respiratory failure. Write common causes of acute
respiratory failure in a 2 year old child. What are the various methods of
oxygen therapy in children. (04/2) 3+3+4
3. Types of Acute Respiratory Failure in children, modes of assisted ventilation
and indications for the same in Children (06) 10
4. What are the criteria used to diagnose Acute Respiratory Distress Syndrome
(ARDS). Write in brief the pathogenesis, clinical features and lab findings of
the same. Discuss the treatment and ventilatory strategies to manage ARDS.
(08/2) 10
5. Describe the pathophysiology, etiology and management of acute respiratory
distress syndrome. (09/2) 3+3+4
CYSTIC FIBROSIS
1. Pathophysiology and clinical features of Cystic Fibrosis (06) 10
ASPIRATION
1. List conditions predisposing children to Aspiration Lung injury. Mention
clinical features and principles of management of Chronic Aspiration.
Conditions predisposing children to aspiration lung injury (07/2) 10
BRONCHIECTASIS
1. Discuss briefly etiology, clinical presentation, diagnosis and treatment of
Bronchiectasis (07/1) 10

33. MISCELLANEOUS
1. Differential diagnosis of Hemoptysis in children (95/2) 10
2. Diagnosis of Bronchial Foreign Body (93/2) 10
3. Write notes on embryological development of abdominal diaphragm and
types of congenital diaphragmatic hernia (06) 10
4. Describe the etiology, stages of evolution, clinical manifestations, diagnostic
investigations and management of empyema thoracis (11/1) 1+2+2+2+3
5. Describe location, structure and function of cilia in respiratory tract. Discuss
the clinical presentation and management of primary ciliary dyskinesia?
(11/2) 3+7
18 CARDIOVASCULAR SYSTEM
HEART FAILURE
1. Intractable congestive heart failure- management approach (02/1) 15
2. Treatment of Intractable CCF (93/2) 10
3. Newer approaches in management of CCF (93/1) 15
4. ACE inhibitors in CCF with congenital heart disease (03/1) 15
5. CCF- Pathophysiology and management (03/2) 25
6. Describe briefly the Pathophysiology of CCF and management of Refractory
Failure (98/2) 25
7. How will you manage a child in Refractory CCF (06) 5
8. Discuss the pathogenesis of Congestive Heart failure and the role of
vasodilators in its management (06) 10
9. Refractory congestive heart failure- causes and management (07/2) 10
10. Discuss the role of vasodilator therapy in congestive heart failure. Enumerate
various vasodilator agents used in CHF and their respective mechanisms of
action. (08/1) 10
HYPERTENSION
1. Discuss the causes of Hypertension in a 7 year old child. Approach of
investigation and management of such a case (02/1) 25
2. Treatment of Hypertension (97/2) 12
3. Investigations in a child with Hypertension (95/1) 10
4. Discuss etiology, diagnosis and management of Childhood Hypertension
(00/1) 25
5. Severe Hypertension in infancy (00/1) 15
6. Diagnosis of Essential Hypertension in children (93/1) 10
7. A 8 year old child is brought with a history of convulsions and altered
sensorium. On examination her BP was 180/110 mm Hg. Discuss the D/D
and laboratory investigations in this child. Discuss the management of

34. Hypertensive Encephalopathy in this child. Add a note on fundus changes in
hypertension. (06) 10
8. Recent advances in management of Hypertension (06/1) 10
9. Discuss the treatment of Hypertension in children. Classify the drugs used to
treat hypertension and briefly mention their mechanism of action (07/2)
10
10. Essential Hypertension in children (07/1) 10
11. A 10 year old boy is brought with a history of convulsions and altered
sensorium. On examination, his BP was 180/110 mm of Hg. Describe
differential diagnosis, laboratory investigations and treatment of this case.
(09/2) 3+4+3
12. Describe the causes and pathogenesis or renal and renovascular
hypertension. Outline principles of management. (12/1) 3+3+4
CONGENITAL CYANOTIC HEART DIAEASE
1. Pathophysiology of Cyanotic spells (02/1) 15
2. How do you classify congenital cyanotic heart disease? Discuss their
investigations (97/2) 15
3. Cyanotic Spell (94/2) 15
4. Complications of Fallot’s Tetralogy and their management (99/2) 10
5. Management of Paroxysmal Hypercyanotic spell (99/2) 15
6. What are the congenital heart diseases associated with cyanotic spells. Write
clinical presentation and management of cyanotic spell. (04/2) 2+3+5
7. How will you manage a child in cyanotic spell (06) 5
8. Pathophysiology, diagnosis and treatment of Eisenmenger Syndrome (07/1)
10
9. Discuss the various minimally surgical invasive devices and procedures
available for the management of common congenital heart diseases in
children (07/1) 10
10. List the causes of congestive heart failure in a 2 years old child. Describe
different types of VSD according to position and size. Write indicators for
surgical intervention/ device closure. (08/1) 10
11. Discuss the hemodynamics and pathophysiology of Tetralogy of Fallot.
Outline management of cyanotic spell in a 2 year old child. (12/1)4+3+3
ARRYTHMIA
1. Classification of cardiac arrythmias and management of WPW Syndrome
(92) 15
2. Arrythmias- pathogenesis, diagnosis and management of different types
(03/2) 15
3. Describe the etiopathogenesis of supraventricular tachycardia in children.
Discuss the diagnosis and management of a child with supraventricular
tachycardia. (04/2) 3+3+4

35. 4. What are the causes, manifestations and management of a young child with
SVT (06) 10
5. Classify stable and unstable arrythmias. Discuss the types of SVT ( Supra
Ventricular Tachycardia) with their ECG changes. Outline the approach to
manage unstable arrythmias. (08/2) 10
6. Classify anti – arrhythmic drugs used in children. Describe the mechanism of
action and uses of Amiodarone. (10/1) 5+5
7. Enumerate the causes and outline the characteristics and treatment of
Supraventricular Tachycardia (SVT) in an infant (10/2) 3+3+4
8. Enumerate life threatening tachyarrhythmias in childhood. How would you
diagnose them? Briefly outline their emergency interventions. (12/1) 2+4+4
CARDIOMYOPATHY
1. Diagnosis of Cardiomyopathy (96/2) 12
2. Cardiomyopathy (95/1) 15
3. Discuss in brief the etiopathogenesis, clinical features and management of
dilated cardiomyopathy. (12/1) 3+3+4
PERICARDITIS
1. Diagnosis and management of Constrictive Pericarditis (99/2) 10
CLINICS
1. Significance of S2 in clinical practice (98/1) 15
2. Enumerate the conditions where you can get
• Loud S2
• Wide splitting S2
Explain the pathophysiology of fixed splitting of S2 (05) 10
3. A one year old child is referred for an asymptomatic cardiac murmur. Outline
the likely causes. How will you differentiate an innocent murmur from that of
a congenital heart disease, on clinical grounds? (09/1) 3+7
RHEUMATIC CARDITIS
1. Treatment of Acute Rheumatic carditis (97/1) 15
INFECTIVE ENDOCARDITIS
1. Pathogens, clinical features and management of infective endocarditis. (10/1)
2+4+4
2. Enumerate common pathogens of infective endocarditis. List conditions/
interventions which require prophylaxis for infective endocarditis in a child
with underlying heart disease. Oultine antibiotic therapy for a child with
RHD and infective endocarditis. (11/1) 2+3+5
MISCELLANEOUS
1. A 13 year old male is brought with an H/o progressive Dyspnea on exertion.
He has past H/o recurrent joint pain. What is the most likely diagnosis? How

36. will you investigate and manage the child. Add a note on Refractory CCF in
a child (05) 5+5
2. Primary Endocardial Fibroelastosis (98/1) 15
3. Cardiovascular Risk factors in children (96/1) 15
4. What advice will you give to a 35 year old patient with coronary artery
disease regarding its prevention in his adolescent son? (06) 10
5. Preventive cardiology in adolescents (07/2) 10
6. Fetal Circulation and cardiovascular adjustments after birth (06/1) 10
7. Outline Fetal Circulation (07/2)
8. Draw a labeled diagram of fetal circulation. Indicate partial pressure of
oxygen (PaO2) and oxygen saturation (SaO2) values at key points in this
circulation. (08/1) 10
9. Fetal circulation and changes after birth (10/1) 5+5
10. Depict diagrammatically fetal circulation. Highlight its unique features
differentiating it from neonatal circulation. Outline important changes
occurring at birth. (11/1) 4+3+3
11. A 3 year old child having fever for 2 days suddenly develops breathlessness,
tachycardia and sweating. Describe the differential diagnosis of this case and
its treatment. (09/2) 5+5
19 DISEASES OF THE BLOOD
ANAEMIA
1. Severe anemia in the first year of life (02/1) 15
2. Describe laboratory investigations in an infant with anemia and briefly
outline the interpretation of test results (95/1) 25
3. Discuss the etiology and investigations in a case of Anemia (94) 25
4. What is peripheral smear finding in (05) 2+2+2+2+2
• Thalassemia Major
• Lead poisoning
• Megaloblastic anemia
• CRF
• Malaria
5. List the causes of microcytic hypochromic anemia. How will you differentiate
between iron deficiency anemia and thalassemia? Discuss briefly the oral
iron chelators. (08/1) 10
6. Discuss the etiology and management of Autoimmune Hemolytic Anemia
(09/1) 3+7
7. Classify causes of acquired pancytopenia. Write briefly about the
management of acquired aplastic anemia. (09/1) 3+7
8. Define pancytopenia. Enlist the causes and assessment of severity of aplastic
anemia in children. (10/1) 2+4+4
9. Discuss the etiology, pathogenesis and diagnostic workup of Acute

37. autoimmune hemolytic anemia. (10/2) 3+3+4
10. List the causes of microcytic hypochromic anemia. Provide differentiating
features between iron deficiency anemia and beta thalassemia trait. Describe
the management of thalassemia major. (11/1) 3+3+4
11. Enlist the red blood cell metabolic enzyme pathways and the enzymes
responsible for hemolysis. Discuss the pathogenesis involved in these
hemolytic anemias. (11/1) 3+7
12. Define pancytopenia. Enumerate common causes in children. How will you
assess severity of acquired anemia in children? (11/2) 2+3+5
THALASSEMIA
1. Genetic basis of Thalassemia syndromes (02/1) 15
2. Current management of Thalassemia Major (96/2) 15
3. Newer modalities in the management of β Thalassemia Major (99/2)
10
4. Antenatal diagnosis of Thalassemia (99/2) 15
5. Recent concepts for treatment of Thalassemia in children (95/2) 10
6. In relation to Thalassemia write a note on the following (05) 10
a. Alkali desaturation test
b. NESTROFT test
c. Peripheral smear
d. SQUID-BLS
e. BMD
7. Outline the antenatal management of a mother with an earlier child with
thalasemia major (07/2) 10
8. Alpha Thalassemia (07/1) 10
IRON DEF ANEMIA
1. Management of Iron Deficiency anemia (98/2) 10
2. Prevention of Iron Deficiency Anemia in children (95/2) 15
3. Enlist the causes and outline the Differential Diagnosis and treatment of
iron deficiency anemia (05) 3+3+4
G6PD DEFICIENCY
1. 3yr old child-H/O Jaundice since 2 months, H/O Exchange transfusion at D2.
Discuss the D/D. Classify Hemolytic Anemia. Add a note on management of
Intravascular hemolysis in G6PD deficiency (05) 4+4+2
2. G6PD deficiency (99/2) 10
3. Pathogenesis of anemia in G6PD Deficiency (99/1) 15
4. Briefly outline normal erythropoiesis. Describe the diagnosis and treatment
of G6PD deficiency (07/2) 10

38. MEGALOBLASTIC ANEMIA
1. Megaloblastic anemia (03/2) 15
2. List the common causes of macrocytic anaemia. Describe the laboratory
diagnosis of megaloblastic anaemia and treatment of juvenile pernicious
anaemia. (04/2) 4+3+3
3. Clinicohematological profile of Megaloblastic Anaemia (06/1) 10
4. Discuss causes, clinical manifestations, laboratory findings and treatment of
Folate Deficiency anaemia in children (07/2) 10
5. Enlist the common causes of macrocytic anemia. Describe the laboratory
diagnosis and treatment of megaloblastic anemia. (09/2) 2+3+5
6. Write short note on: Peripheral smear findings in iron deficiency and B12
deficiency anemia (10/2) 2.5+2.5
HEREDITARY SPHEROCYTOSIS
1. Diagnosis and management of Congenital Hereditary Spherocytosis (97/1)
15
2. Hereditary Spherocytosis (06) 10
SICKLE CELL ANEMIA
1. Management of acute sickle cell crisis (99/1) 15
SPLEEN
1. Outline the functions of Spleen. Describe the indications and complication of
splenectomy and post – operative management. (09/1) 3+7
2. Describe the functions of spleen. Describe clinical manifestations and
management of asplenia/ polysplenia. (10/1) 4+3+3
HEMRRHAGIC AND THROMBOTIC DISEASES
1. Antenatal diagnosis and career detection of Hemophilia (98/2) 15
2. DIC (96/2) 15
3. Write differential diagnosis of a 5 year old child with petechial rash with
fever. How will you manage a child with idiopathic thrombocytopenic
purpura. (04/2) 4+6
4. Explain coagulation cascade. A 4 year old child with h/o recurrent epistaxis
and gum bleeding. Discuss laboratory diagnosis and management of this
condition.
Add a note of differentiating a bleeding disorder from a coagulation disorder
(05) 5+3+2
5. A 5 year old male child comes with a history of trivial fall and swelling of
right knee. He has history of easy brusiability. Discuss the laboratory

39. diagnosis and management of this child. Add a note on antenatal diagnosis
and counseling (06) 10
6. Various treatment modalities in acute ITP (06) 10
7. Discuss the various aspects of management of a child with Hemophilia A
(07/2) 10
7. Discuss the pathogenesis of disseminated intravascular coagulation (DIC) and
relate it to the laboratory abnormalities observed in this entity. (08/1) 10
8. Diagrammatically outline the Normal Coagulation Cascade. Outline diagnosis
and management of disseminated Intravascular Coagulation (DIC) (09/1) 4+6
13. Write in brief regarding the etiology and management of idiopathic
thrombocytopenic purpura.(ITP) (11/1) 4+6
14. A 10 year old boy with hemophilia A, weighing 30 kg has come with bleeding
in both knee joints. Discuss briefly the specific, supportive and prophylactic
management of this child. (11/1) 4+3+3
BONE MARROW TRANSPLANTATION
1. Describe the risks and benefits of bone marrow transplantation in children
(94/2) 15
2. Bone marrow transplantation for children (06/1) 10
3. Define febrile neutropenia and describe the treatment and care of a child
with febrile neutropenia. (08/1) 10
4. Enumerate the methods of harvesting/ storing stem cells. Outline the
indications of stem cell therapy. Discuss in brief the patient preparation
required for stem cell therapy. Enlist important potential complications of
stem cell therapy. (11/1) 2+3+3+2
BLOOD TRANSFUSION
1. Transfusion of Blood fractions 10
2. Discuss the inherent hazards of Blood Transfusion in children and the
necessary measures to avoid and minimize them (07/1) 10
3. Outline the method of extracting various blood components. What are the
indications of usage of Fresh Frozen Plasma (FFP) and cryoprecipitate?
(09/2) 5+5
20 NEOPLASTIC DISEASES AND TUMOURS
ALL
1. Treatment and prognosis of ALL (97/2) 15
2. Management of CNS Leukemia (96/1) 14
3. Management of a case of ALL in a 3 year old (03/1) 25
4. Discuss management of a child with acute leukemia (06/1) 10

40. 5. Management of a child with acute leukemia (06/2) 10
6. Prognostic indicators in Acute Leukemia (07/2) 10
7. Utility of immunophenotyping in the diagnosis of leukemia in children.
Outline the treatment of acute lymphoblastic leukemia. (09/2) 4+6
LYMPHOMA
1. Different types of Lymphomas in children and their Histopathological
classification (93/2) 15
MISCELLANEOUS
2. Define tumour lysis syndrome. Enlist its important constituents. Outline its
etiology and describe the management. (08/1) 10
3. Write in brief the clinical manifestations, laboratory findings and
management principles of Langerhans Cell Histocytosis. (09/1) 10
4. Classify childhood histiocytosis. Describe the clinical manifestations,
diagnosis and treatment of Langerhan’s cell histiocytosis. (10/1) 3+3+2+2
5. Outline the essential components and pathophysiology of tumor lysis
syndrome. Describe its management. (11/1) 2+4+4
6. How will you classify childhood Histiocytosis? Describe the diagnostic
criteria, clinical manifestations and treatment for hemophagocytic
lymphohistiocytosis. What are the infections associated with it? (11/2)
2+2+2+2+2
7. Define tumour lysis syndrome. Describe the pathophysiology of tumour lysis
syndrome. How will you prevent occurrence of tumour lysis syndrome?
(11/2) 2+4+4
21 UROLOGIC DISORDERS IN INFANTS AND CHILDREN
ENURESIS
1. Define Enuresis. Discuss its manifestations and management (06) 5
2. Enuresis (96/2) 15
3. Management of nocturnal Enuresis (07/1) 5
4. What is nocturnal enuresis? Outline the causes for the same. Describe the
modalities for managing a 6 year old child with enuresis. (08/2) 10
5. Discuss evaluation and management of an 8 year old male with primary
nocturnal enuresis. (10/2) 4+6
UTI
1. Imaging studies indicated in a child with UTI (06) 10
2. Recurrent UTI in childhood (02/1) 15
3. Management of a 2 year old child with first attack of UTI (99/2) 10
4. Describe the etiological factors, clinical manifestations and management of
children with UTI (95/2) 25
5. Investigation of a 7 year old boy with Recurrent UTI (93/2) 10

41. 6. Recurrent UTI (03/2) 15
7. Classify UTI and provide an algorithm for management of a child with first
episode of UTI (05) 3+7
8. Discuss approach to a child with recurrent urinary tract infections. What are
the indications, goal and schedule of antimicrobial prophylaxis in treating
such a child? (09/1) 10
9. What are the clinical manifestations of urinary tract infections (UTI) in
children? Describe the plan of investigations and management of a 2 year old
boy with recurrent UTI. (09/2) 2+4+4
10. Write short note on: Grading of vesico-ureteric reflux and indications of
surgical intervention in children with vesico-ureteric reflux (10/2) 3+2
VUR
1. Management of an infant with VUR (93/1) 15
2. Discuss criteria for diagnosis, staging and management of VUR (92) 25
3. Outline the grades of vesico-ureteric reflux. Discuss the management of a
child with recurrent urinary tract infection with grade 4 vesico-ureteric
reflux. (04/2) 4+3+3
4. Give the grading of VUR. Outline its evaluation and management in
children(07/2) 10
5. Clinical features, grading and management of vesico-ureteric reflux (10/1)
3+3+4
6. Define vesicoureteral reflux (VUR). Classify the grades of VUR. Discuss in
brief the medical and surgical management of VUR in children. (11/1) 2+2+6
NEUROGENIC BLADDER
1. Neurogenic Bladder (98/2) 15
GYNAECOLOGY
1. Write a short note on non-specific vulvo-vaginitis in children with special
emphasis on its etiopathogenesis and treatment (08/1) 10
22 ENDOCRINE SYSTEM
THYROID GLAND
1. Management of Puberty Goiter (98/2) 15
2. Diagnosis of Congenital Hypothyroidism (95/1) 15
3. Endemic Cretinism (99/2) 15
4. Congenital Hypothyroidism (00/1) 15
5. Etiopathology of Congenital Hypothyroidism 15
6. Management of Puberty Goiter (93/1) 15
7. Goitrogenic Hypothyroidism (03/2) 15
8. Briefly list the various thyroid function tests. Describe clinical presentation
and management of autoimmune thyroiditis. (04/2) 6+4

42. 9. What are the changes seen in Thyroid Hormone levels around birth.
Describe the salient features of Neonatal Thyroid Screening Programme
(06) 10
10. Neonatal Thyroid Screening (07/2) 10
11. Discuss causes, clinical features and management of Acquired
Hypothyroidism (07/2) 10
12. Congenital Hyperthyroidism (07/1) 10
13. Discuss the synthesis of thyroid Hormones. Outline the causes of congenital
hypothyroidism and a brief comment on neonatal thyroid screening. (09/1)
3+7
14. Thyroid hormone synthesis and its derangements. (10/1) 6+4
15. Enlist common causes of acquired hypothyroidism in a 12 year old girl.
Discuss in brief the clinical manifestations and laboratory findings. (12/1)
3+4+3
DIABETES MELLITUS
1. Describe briefly the biochemical changes and management of DKA (98/1)
25
2. Complications of Juvenile Diabetes Mellitus and their management (97/1)
15
3. Management of DKA (95/2) 15
4. Emergency management of DKA (93/1) 15
5. 8 year, h/o vomiting, severe abdominal pain for 2 days. Dehydrated, acidotic
breathing, Blood glucose (random) 400. Outline the management (05) 10
6. Write management of DKA (06) 5
7. Management of a child with IDDM (06/2) 10
8. Write risk factors, pathogenesis and treatment of Type 2 Diabetes Mellitus in
children (07/2) 10
9. Classify severity of diabetic ketoacidosis on the basis of clinical and blood gas
examination. Briefly describe Somogyi and Dawn phenomenon in type 1
diabetes. (08/1) 10
10. Discuss the metabolic changes associated with diabetic ketoacidosis with
steps of treatment of diabetic ketoacidosis. (08/2) 10
11. A 10 year old child (body weight 22kg) presents with severe diabetic
ketoacidosis. Write down the expected clinical and investigate findings.
Outline the plan of management in first 24 hours. (09/1) 4+6
12. What are the biochemical criteria for the diagnosis of Diabetic Ketoacidosis
(DKA)? What are the goals of therapy? How will you manage a child with
DKA? (11/2) 3+3+4
HYPOTHALAMUS AND PITUITARY
1. What are the causes of Dwarfism? How will you investigate such a case
(97/2) 15
2. SIADH (99/1) (99/2) 10
3. Indications of Growth Hormone Therapy (93/2) 10

43. 4. Define Short Stature. Discuss the approach to a child with short stature
and the role of GH in Short Stature (05) 2+5+3
5. How will you diagnose and treat SIADH in a child (06) 5
6. How will you assess a child presenting with features of Diabetes Insipidus
(06) 10
7. A 4 year old child presents with polydipsia and polyuria. How will you
establish a diagnosis of diabetes insipidus in this case? Discuss its
management. (08/1) 10
8. Short stature – definition, differential diagnosis and management
approach. (10/1) 2+3+5
9. Diagnostic approach for a child who presented with polyuria and
polydipsia. (10/1) 10
10. Outline the diagnostic criteria of diabetes insipidus. Discuss the
management of nephrogenic diabetes insipidus. (10/2) 4+6
11. Enumerate the hormones secreted by anterior pituitary and list the factors
stimulating and inhibiting secretion of growth hormone. (10/2) 3+7
12. Outline the diagnostic criteria for Syndrome of Inappropriate ADH
Secretion (SIADH). Discuss its etiopathogenesis. (12/1) 6+4
ADRENAL GLAND
1. Management of adrenogenital syndrome (96/2) 15
2. Short note- female with Ambiguous genitilia at birth (02/1) 15
3. Salt losing CAH (03/1) 15
4. Outline human sex differentiation. Provide an outline of the approach to an
infant with ambiguous genitalia. (04/2) 4+6
5. Explain synthesis of Steroid Hormones. Discuss Briefly approach to a child
born with ambiguous genitilia (05) 5+5
6. Causes of Adrenal Crises and discuss its management (06) 10
7. Discuss approach to a child with ambiguous Genitilia (06/2) 10
8. Diagnosis and management of a child with CAH (06/1) 10
9. Enumerate the causes of adrenal crisis. Provide key features of clinical
presentation and discuss its management. (08/1) 10
10. Discuss karyotype abnormalities, clinical features and management of true
hermaphroditism. (08/1) 10
11. Define delayed puberty in a male child. List the possible causes. Describe
changes in male genitals in different stages of sexual maturation. (08/2) 10
12. Discuss the normal physiology of puberty and its relation to sexual
development. (09/1) 4+6
13. A 1 ½ year old female is brought to you with obesity, short stature,
hypertension and hypertrichosis of face and trunk. Provide differential
diagnosis and approach to investigating and managing this child. (09/1) 3+7
14. Describe the diagnostic approach in a 2 year old child with ambiguous
genitalia (09/2) 10
14. Physiology of puberty in boys and girls (10/1) 10
15. Clinical features, investigations and treatment of pheochromocytoma. (10/1)

44. 3+3+4
16. Outline the diagnostic approach to a 14 years old boy with infantile
genitalia. (10/1) 10
17. Define and classify precocious puberty in boys according to its etiology.
Outline the approach for investigating a boy with precocious puberty. (11/1)
2+4+4
18. Describe normal sexual differentiation in fetus. What is intersex? Describe
etiological classification of disorders of Sex Development (DSD). (11/2)2+2+6
PARATHYROID GLAND
1. Role of hormones in calcium balance (03/2) 15
2. Outline the calcium metabolism. Discuss the causes and management of
Hypocalcemia in a 3 yrs old (07/2) 10
3. Differentiate between the laboratory features of hypoparathyroidism,
pseudohypoparathyroidism and hyperparathyroidism. (08/1) (12/1) 10
4. Describe the calcium metabolism in a child. Detail the clinical manifestation,
diagnosis and treatment of a child with pseudohypoparathyroidism. (08/2) 10
5. Discuss the etiopathogenesis, clinical manifestations, diagnosis and treatment
of hypercalcemia. (09/1) 10
23 NERVOUS SYSTEM
CNS INFECTIONS
1. Chronic Meningitis – clinical approach and management (02/1) 15
2. Discuss diagnosis and management of Viral Encephalitis (97/1) 15
3. Pathophysiology of Acute Encephalitis (03/1) 15
4. Pathogenesis, management and prognosis of H.Influenzae Meningitis in
children (06) 10
5. Discuss briefly epidemiology, investigations and management of Viral
Meningoencephalitis (07/1) 10
6. Enumerate risk factors for brain abscess. Outline a scheme for investigating
and treatment a 10 year old child with brain abscess. (08/1) 10
7. Discuss the etiology, clinical presentation, diagnosis and treatment of Acute
Disseminated Encephalomyelitis (ADEM) (09/1) 4+6
8. Enumerate risk factors for brain abscess. Outline investigations and
treatment of brain abscess in children. (09/2) 4+2+4
NEUROLOGICAL EVALUATION
1. Outline the pathway of seventh cranial. Discuss the diagnosis and
management of Bell’s palsy. (04/2) 4+3+3
2. Briefly discuss the role of electrophysiological studies in pediatric
neurological disorders. (04/2) 10

45. 3. What are the signs of meningeal irritation in a 2 year old child? How do you
elicit them? How will you rule out Pseudo-neck rigidity (05) 10
4. Give 5 examples each of UMN and LMN lesion. How do you clinically
differentiate between UMN and LMN lesions? What is the importance of
fundus examination in a child with Para paresis (05) 10
5. Modified Glasgow Coma Scale in a 1 year old Child (03/1) 15
6. Clinical significance of Postural Reflexes (06) 10
SEIZURES IN CHILDHOOD, CONDITIONS MIMICKING SEIZURES
1. Enumerate newer drugs for treatment of Epilepsy with their uses (02/1)
15
2. Pseudoseizures (98/2) 10
3. Management of a case of Complex Partial Seizure (98/2) 10
4. Breath Holding spells (98/1) 15
5. Etiology and management of Febrile Seizures (98/1) 15
6. What are the causes of convulsions in infancy and childhood How will you
investigate such a case (97/2) 15
7. Treatment of Breath Holding spells (97/1) 10
8. Classification of Epilepsy and treatment of Simple Partial Seizures (96/2)
12
9. Management of children with partial epilepsy (95/1) 15
10. Infantile spasms (99/2) 10
11. Conditions mimicking seizures (99/2) 15
12. Partial Seizures 15
13. Approach to an infant with myoclonic seizures (00/1) 15
14. Treatment of Status Epilepticus in a 5 year old Child (95/2) 10
15. Management of Children with Partial Seizures (95/1) 15
16. Benign Rolandic Epilepsy of Childhood (93/1) 15
17. Definition, prognosis and management of Febrile Convulsion (93/1) 15
18. What are the causes of Convulsions in children? Discuss the management of
Status Epilepticus (05) 5+5
19. Define Febrile Convulsions. Discuss the management of a 2 year old child
who presents to the emergency room with first episode of Febrile Seizure.
Add a note on anticonvulsant Prophylaxis in febrile seizure. (06) 10
20. Diagnosis and management of a child with Partial Focal Seizure (06/2) 10
21. Discuss conditions that mimic seizures in children (07/2) 10
22. Indications for the therapeutic use of newer anticonvulsants in childhood
seizure states and their potential adverse effects (07/1) 10
23. Newer Antiepileptic drugs (99/1) 15
24. An 8 year old apparently well boy presents with generalized seizures for the
last one hour. How will you approach (including history and examination)
this child? Discuss the management of this patient. (08/2) 10
25. Write the characteristic features of febrile seizures in children. Enumerate
the differentiating points for atypical febrile seizure. Outline the indications
and regime for continuous prophylaxis in febrile seizures. (10/2) 2+2+3+3