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The Mini-Gastric Bypass:The Mini-Gastric Bypass:
Best Treatment Type 2 DiabetesBest Treatment Type 2 Diabetes
MellitusMellitus
Dr K S Kular
Kular Medical Education & Research Society ,
Kular Group of Institutes ,
drkskular@gmail.com
www.kularhospital.com
Best Rx for Diabetes
5 Objectives
1. Consider Band/Sleeve/RNY/MGB
2. Best Rx DM Requires
Gastric Procedure + Duodenal Bypass
3. Eliminates Band/Sleeve; Choice RNY vs MGB
4. RNY Most Technically Difficult Dangerous &
Deadly form of Bariatric Surgery
5. Data MGB One of the Most Effective & Safest
Rx for DM
Objective 1:
Consider Band/Sleeve/RNY/MGB
Objective 2:
Best Treatment of Diabetes Includes
Both a Gastric Procedure + Duodenal Bypass
Data from
General Surgery,
Bariatric Reports,
Animal Studies
Objective 2:
Animal Models Confirm
Duodenal Bypass Improves Effectiveness
“This study shows that
bypassing Duodenum
Improves T2D,
independently of
food intake, body weight, malabsorption, or
nutrient delivery”
The Mechanism of Diabetes Control After Gastrointestinal Bypass Surgery Reveals a Role of the Proximal
Small Intestine in the Pathophysiology of Type 2 Diabetes. Rubino,); Marescaux, Jacques MD, FRCS
Annals of Surgery; 244 (5): 741-749, November 2006
Objective 2: Billroth I vs Billroth II
Gastrectomy vs Gastrectomy + Bypass
Primary Gastric Procedure (PGP)
Vs
Combined Gastric + Bypass (CGB)
Which Leads to Greater Weight Loss?
Which Leads to Greater Resolution of Diabetes?
General Surgery Answer:
Bariatric Surgeons Should Not Forget Their General
Surgery Training
GS for Gastric Disease (Ca/Ulcer)
Gastrectomy ALONE 50%
Gastrectomy + Duodenal Bypass 75%
Rx T2D MUST Include
Duodenal Bypass for
BEST short and long term Efficacy
G.O. Less Effective G+D
G.O.=Gastric Only vs
G+D=Gastric + Duodenal
Outcome after gastrectomy in gastric cancer
patients with type 2 diabetes
• 403 gastric cancer patients with T2DM
• BMI % Reduction
• Duodenal Bypass:
• BI: No Bypass 7.6%
• BII: Bypass 11.4%
• ** 50% Improvement **
• Jong Won Kim, etal, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul 135-
720, South Korea, World J Gastroenterol. 2012 January 7; 18(1): 49–54.
Objective 2: General Surgery
"Effect of Gastrectomy For 
Stomach Cancer on
Type 2 Diabetes Mellitus"
Kang KC, Shin SH, Lee YJ, Heo YS.
J Korean Surg Soc. 2012 Jun;82(6):347-55.
Department of Surgery, Inha University Hospital, Inha University School of
Medicine, Incheon, Korea.
Objective 2: Gastrectomy for stomach 
cancer on type 2 diabetes (Kang)
75 GCa Pts, 35 month FU
BI vs BII Rx DM
Gastrectomy ALONE (i.e. Sleeve)
0% Resolved, 45% improved
Gastrectomy + BII (i.e. MGB)
22% Resolved, 85% Improved
Objective 2: General Surgery
J Gastrointest Surg. 2012Jan;16(1):45-51
Gastrointestinal metabolic surgery for the
treatment of diabetic patients: a multi-
institutional international study.
Lee WJ, Hur KY, Lakadawala M, Kasama K, Wong
SK, Lee YC.
Gastrointestinal metabolic surgery for the treatment of
diabetic patients (Lakadawala)
200 patients,
Gastric Bypass vs Sleeve gastrectomy
Remission of T2DM
“Gastric Bypass pts (Gastric + Bypass)
lost more weight & higher diabetes remission Sleeve pts“
Bypass pts mix of MGB/RNY
(per Dr. Lee)
Objective 2: MGB vs Sleeve
Mini-Gastric bypass
vs Sleeve Gastrectomy
for type 2 diabetes mellitus: a
Randomized Controlled TrialRandomized Controlled Trial
Lee WJ, Chong K, Ser KH, Lee YC, Chen SC, Chen JC, Tsai MH, Chuang
LM. Arch Surg. 2011 Feb
Objective 2: Lee MGB vs Sleeve
Randomized Controlled Trial
Randomized controlled trial
60 moderately obese patients (body mass index >25 and
<35)
Outcome was remission of T2DM (fasting glucose <126
mg/dL and HbA(1c) <6.5% without glycemic therapy)
All completed the 12-month follow-up
Lee MGB vs Sleeve
Randomized Controlled Trial
Remission of Diabetes
** 93% ** Mini-gastric bypass
** 47% ** Sleeve gastrectomy
(P = .02)
Lee MGB vs Sleeve
Randomized Controlled Trial
Mini-gastric bypass
lost more weight,
achieved a lower waist circumference, and
Lower glucose, HbA(1c), and
blood lipid levels than
the sleeve gastrectomy group
Effectiveness of Bariatric Procedures
Gastric + Duodenal Bypass
Outperforms Gastric Alone
G.O. Band Poor
G.O. Sleeve Med High
G+D RNY High
G+D MGB High - Highest
Conclusions
Band & Sleeve
Less Effective than
RNY & MGB
Objective 3: Best Rx DM
Gastric Procedure + Duodenal Bypass
This Excludes Band/Sleeve
Need for Gastric Procedure +Bypass
Eliminates Band/Sleeve;
Leaves Choice RNY vs MGB
Objective 4:
RNY is the most
Technically Difficult,
Dangerous & Deadly
form of Bariatric
Surgery
100s Refs
One Recent Example
RNY is the MOST Dangerous Form of Bariatric
Surgery
By Every measure, in Every study RNY
Highest Death Rate, Highest Leak Rate Highest Early
ComplicationsHighest Major Complication Rate
Highest Bleeding Rate, Highest Re-operation Rate
Highest PE Rate....
RNY is the most dangerous form of Bariatric Surgery
References 25-100 Studies
RNY: Long learning curve of
500 cases
RNY technically challenging
2,281 cases 1999 - 2011
Complications Stabilized after *500* cases
Mortality rate .43%,
main causes of death PE & Leaks (.14% each)
Op time & Complications significantly reduced after a
long learning curve of 500 cases
Surg Obes Relat Dis. 2013 Feb 11. Overcoming the learning curve of laparoscopic Roux-en-Y gastric bypass: A 12-
year experience. El-Kadre L, Tinoco AC, Tinoco RC, Aguiar L, Santos T. Department of Surgery, São José do
Avaí Hospital, Itaperuna, Rio de Janeiro, Brazil.
Lap RNY Gastric Bypass
Med Coll Va.
Postoperative Complications L-RNY
Leak 4.5%
SBO 2%
PE 1%
Death 0.7%
Ann Surg. 2004 May; 239(5): 698–703. Multivariate Analysis of Risk Factors for
Death Following Gastric Bypass for Treatment of Morbid Obesity, Adolfo Z.
Fernandez, Jr, MD et al.
RNY Bypass Surgery for Diabetes With Nonmorbid
Obesity? Maybe Jun 04, 2013
Controlled Prospective Rndomized 12-months, 49% RNY pts vs 19%
lifestyle pts met primary end points
BUT
37% serious complications in the RNY group
2 most serious complications were anastomotic leak 3.3%!!,
1 patient suffered anoxic brain injury.
Patients who underwent surgery were also more likely to have
nonserious adverse events such as nutritional deficiencies.
JAMA. 2013 Jun 5;309(21):Roux-en-Y gastric bypass vs intensive medical management for the control of type 2 diabetes, hypertension, and hyperlipidemia: the
Diabetes Surgery Study randomized clinical trial. Ikramuddin S, Department of Surgery, School of Public Health, University of Minnesota, Minneapolis, MN 55455,
USA. ikram001@umn.edu
RNY Bypass Surgery for Diabetes
Controlled Prospective Randomized Trial
Normal HgbA1C level range from 4.5 to 6
Only 44% RNY pts HgbA1c < 6 (Cure)
BUT
37% serious complications in the RNY group
3.3% anastomotic leaks
1 patient suffered anoxic brain injury.
JAMA. 2013 Jun 5;309(21):Roux-en-Y gastric bypass vs intensive medical management for the control of type 2 diabetes, hypertension, and hyperlipidemia: the Diabetes
Surgery Study randomized clinical trial. Ikramuddin S, Department of Surgery, School of Public Health, University of Minnesota, Minneapolis, MN 55455, USA.
ikram001@umn.edu
1 yr RNY
Did Not
Reach
Normal
HgbA1c
JAMA. 2013 Jun 5;309(21):Roux-en-Y gastric bypass vs intensive medical management for the control of type 2 diabetes, hypertension, and hyperlipidemia: the Diabetes
Surgery Study randomized clinical trial. Ikramuddin S, Department of Surgery, School of Public Health, University of Minnesota, Minneapolis, MN 55455, USA.
ikram001@umn.edu
First report from the
American College of Surgeons
Bariatric Surgery Center Network
28,000 Patients
Ann Surg. 2011 Sep;254(3):410-20
Hutter MM, Schirmer BD, Jones DB, Ko CY, Cohen ME, Merkow
RP, Nguyen NT.
Department of Surgery, Massachusetts General Hospital, Boston, MA
02114, USA.
American College of Surgeons Bariatric Surgery
Center Network
Outcome SG N (%) RNY N (%)
Conv to Open 9 (0.10) 207 (1.43)
30-day Mortality 1 (0.11) 21 (0.14)
1-Year Mortality 2 (0.21) 49 (0.34)
Readmission 51 (5.4) 937 (6.47)
Reoperation 28 (2.97) 728 (5.02)
First report from the American College of Surgeons Bariatric Surgery Center Network28,000 Patients
American College of Surgeons Bariatric Surgery
Center Network
Outcome LSG N (%) RNY N (%)
Coma 0 2 (0.01)
Stroke 0 5 (0.03)
Cardiac Arrest 0 13 (0.09)
Myocard Infarct 0 9 (0.06)
DVT 1 (0.11) 21 (0.14)
Pneumonia 3 (0.32) 58 (0.40)
American College of Surgeons Bariatric Surgery
Center Network
Outcome SG N (%) RNY N (%)
Intubation 3 (0.3) 59 (0.41)
Ventilator (> 48 hrs) 0 55 (0.38)
Acute Renal Failure 0 22 (0.15)
UTI 5 (0.5) 104 (0.7)
Wound Dehiscence 0 27 (0.19)
Septic Shock 0 21 (0.14)
Controlled Prospective Randomized Trial
Lee WJ, Yu P-J, Wang W, Chen TC, Wei PL, Huang MT. Laparoscopic Roux-en-Y versus Mini-Gastric Bypass
for the treatment of Morbid Obesity. Ann Surg 2005 ; 242 : 20-28
RYG Bypass Mini Bypass
Op time (mns) 205 148
Early complications 20% 7.5%
Late complications 7.5% 7.5 %
EWL at one year 58.7% 64.9%
EWL at two years 60% 64.4%
Objective 5:
MGB One of the Most Effective & Safest
Best Rx for DM
Objective 5:
MGB One of the Most Effective & Safest
MGB Series
Rutledge U.S.A. 6,000 + (16 yr + FU)
Lee Taiwan 1000 + (RCT, 10 yr+ FU)
Noun Lebanon 1000
Kular India 1000+
Cady France 2000 +
Peraglie U.S.A. 2000 +
Carbajo Spain 2000 +
Garcia-Caballero Spain 1000 +
Musella et al. Italy 1000
Otheres (i.e. Chevallier Paris , Tacchino Rome etc.)
MGB One of the Most Effective & Safest
MGB Series
Findings in all series are the same:
Short operation, low risk of short and long term
complications
Excellent short and long term weight loss 75-100% EWL,
Better than BPD)
Revisable and Reversible
Minimal Risk of Bile Reflux in Knowledgeable Hands
One Thousand Consecutive Mini-gastric Bypass:
Short- And Long-term Outcome
1,000 patients who underwent MGB from November 2005 to January
2011
Operative time and length of stay for primary vs. revisional MGB were
89 ± 12.8 min vs. 144 ± 15 min (p < 0.01) and
l.85 ± 0.8 day vs. 2.35 ± 1.89 day (p < 0.01)
Short-term complications 2.7% for primary vs. 11.6% for revisionnal
MGB (p < 0.01)
Obes Surg. 2012 May;22(5):697-703. One thousand consecutive mini-gastric bypass: short- and long-term outcome. Noun et al,
Department of Digestive Surgery, Hôtel-Dieu de France Hospital and University Saint Joseph Medical School, Bd Alfred Naccache,
Achrafieh, BP 166830 Beirut, Lebanon. rnoun@wise.net.lb
One Thousand Consecutive Mini-gastric Bypass:
Short- And Long-term Outcome
Five (0.5%) patients presented with leakage from the gastic tube but
none had anastomotic leakage.
Four (0.4%) patients, all revisions with severe bile reflux Rx by
stapled latero-lateral jejunojejunostomy (Braun).
Excessive weight loss occurred in four patientseasily revised.
Percent excess weight loss (EWL) of 72.5% occurred at 18 months.
Obes Surg. 2012 May;22(5):697-703. One thousand consecutive mini-gastric bypass: short- and long-term outcome.
Noun et al, Department of Digestive Surgery, Hôtel-Dieu de France Hospital and University Saint Joseph Medical
School, Bd Alfred Naccache, Achrafieh, BP 166830 Beirut, Lebanon. rnoun@wise.net.lb
One Thousand Consecutive Mini-gastric Bypass:
Short- And Long-term Outcome
The 50% EWL was achieved for 95% of patients at 18 months and for
89.8% at 60 months.
MGB is an effective, relatively low-risk, and low-failure bariatric
procedure.
In addition, it can be easily revised, converted, or reversed.
Obes Surg. 2012 May;22(5):697-703. One thousand consecutive mini-gastric bypass: short-
and long-term outcome. Noun et al, Department of Digestive Surgery, Hôtel-Dieu de
France Hospital and University Saint Joseph Medical School, Bd Alfred Naccache,
Achrafieh, BP 166830 Beirut, Lebanon. rnoun@wise.net.lb
Laparoscopic Roux-en-y Vs. Mini-gastric Bypass For The
Treatment Of Morbid Obesity: A 10-year Experience.
Obes Surg. 2012 Dec;22(12):1827-34. Laparoscopic Roux-en-Y Vs.
mini-gastric bypass for the treatment of morbid obesity: a 10-
year experience.
Lee WJ, Ser KH, Lee YC, Tsou JJ, Chen SC, Chen JC.
Department of Surgery, Min-Sheng General Hospital, National
Taiwan University, No. 168, Chin Kuo Road, Tauoyan, Taiwan,
Republic of China. wjlee_obessurg_tw@yahoo.com.tw
Laparoscopic Roux-en-y Vs. Mini-gastric Bypass For The
Treatment Of Morbid Obesity: A 10-year Experience.
October 2001 and September 2010, 1,657 patients who received
gastric bypass surgery (1,163 for LMGB and 494 for LRYGB)
Surgical time was significantly longer for LRYGB (159.2 vs. 115.3
min for LMGB, p<0.001).   
The major complication rate was higher for LRYGB (3.2 vs. 1.8%, p 
=0.07). 
5 years after surgery, the mean BMI was lower in LMGB than
LRYGB (27.7 vs. 29.2, p<0.05) and   
LMGB also had a higher excess weight loss than LRYGB (72.9 vs.
60.1%, p<0.05).   
Late revision rate was LRYGB 3.6% and MGB 2.8%
Laparoscopic Roux-en-y Vs. Mini-gastric Bypass For The
Treatment Of Morbid Obesity: A 10-year Experience.
CONCLUSIONS:
This study demonstrates that MGB
can be regarded as a SIMPLER and
SAFER alternative to RNY with
similar or BETTER efficacy at a 10-
year experience.
Surgery Can Successfully Treat Obesity and Diabetes in Both
Thin and Obese Diabetic Patients
• 2013: Kular
Hospital
• 6 year study
T2DM patients
• Results:
• Type 2 Diabetes
resolved
• 98% of MGB
MGB More Effective than BPD
Dr Tacchino MGB vs BPD
Weight Loss and Diabetes Resolution Following Mini-
Gastric Bypass and Bilio-Pancreatic Diversion. Tacchino R.,
Rutledge R., Università Cattolica del Sacro Cuore, Rome, Italy
408 pts Jan 2007 to Dec 2009
36 months follow-up
Mini-Gastric Bypass (n = 164) initial BMI 46.4±9.6 or
Bilio-Pancreatic Diversion (n = 244) initial BMI 46.9±7
(Tacchino’s perferred Operation)
MGB More Effective than BPD
Dr Tacchino MGB vs BPD
RESULTS:
Mean BMI at two years was 28.5±3.9 kg/m2 and at three
years 27.4±4.5 kg/m2 after MGB
BMI at two years 32.7± 6.04 kg/ m2 and at three years
33.6±5.1 kg/m2 after BPD
One year resolution of diabetes was accomplished in:
100% in MGB group
95% in BPD group.
MGB More Effective than BPD
Dr Tacchino MGB vs BPD
Tacchino’s conclusions:
“Both MGB and BPD resluted in excellent weight loss,
excellent resolution of co-morbities with low risk of long
term complications.
The MGB was associated with greater weight loss than
BPD.
Improvements in other cardiovascular risk factors and
quality of life were similar after both procedures.”
Randomized Controlled Prospective Trials
MGB MUCH Superior to RNY Rx Diabetes
MGB vs RNY Rx Diabetes, Two Controlled Prospective Randomized
Trials
Ikramuddin S, et al. Roux-en-Y gastric bypass vs intensive medical management for the control of type 2 diabetes, hypertension, and
hyperlipidemia: the Diabetes Surgery Study randomized clinical trial. JAMA. 2013 Jun
Lee WJ, et al. Gastric bypass vs sleeve gastrectomy for type 2 diabetes mellitus: a randomized controlled trial. Arch Surg. 2011 Feb
Resolution of Diabetes at 12 months
Sleeve 47%
RNY 44%
MGB 93%
Conclusions: MGB Best Rx for DM
1. Band/Sleeve/RNY/MGB
2. Animal, Gen Surg and Bariatric Data:
Best Rx = Gastric + Duodenal Bypass
3. Excludes Band/Sleeve
4. RNY Unquestionably the Most Dangerous form of
Bariatric Surgery
5. Numerous studies show MGB short safe and highly
effective; Best Choice
Which Is More DeadlyWhich Is More Deadly
A Hot Dog Or A Billroth II?A Hot Dog Or A Billroth II?
Which Is More Deadly A Hot Dog Or A Billroth II?
Processed meats
(Bacon, sausage, hot dogs, sandwich meat, packaged ham,
pepperoni, salami, etc.)
Shown to be associated with gastric cancer.
An increase intake of 100 g of processed meat per day
Increases the risk of Gastric Cancer by 3.5 times
= Natl Cancer Inst. 2006 Mar 1;98(5):345-54. Meat intake and risk of stomach and esophageal adenocarcinoma within
the European Prospective Investigation Into Cancer and Nutrition (EPIC).
= J Natl Cancer Inst. 2006 2;98(15):1078 "Processed meat consumption and stomach cancer risk: a meta-analysis" The
Karolinska Institutet
(Hint: A Hot Dog weight 3.7 oz = 100 g = INCREASED RISK 3.5!)
Which is more deadly a Hot Dog or a
Billroth II?
AA BB
https://www.surveymonkey.com/s/IFSO-MGB-ConsensusConference
Or Email DrR@clos.net
Which is more deadly a Hot Dog or a Billroth II?
Which Do Bariatric Surgeons Fear More?
A Hot Dog or a Billroth II?
AA BB
https://www.surveymonkey.com/s/IFSO-MGB-ConsensusConference
Or Email DrR@clos.net
UNINFORMED FEAR BILLROTH II
EDUCATED USE BILLROTH II
• 1. Gastric Cancer Declining Rapidly, > 50%
• 2. Gastric Cancer Cause:
Environmental Factors / Easily Prevented
Diet, Lifestyle changes and Rx of H. Pylori
(Avoid Etoh, smoking, processed & salted meats and
foods, seek high intake of fruits and vegetables)
UNINFORMED FEAR BILLROTH II
EDUCATED USE BILLROTH II
• 3. Some studies Slight Increased Risk of gastric cancer
after 20 – 30 years (RR 1.5):
But: BII was performed to Rx Ulcer =>
Ulcer => Increased Risk
• (Worried? Rx H Pylori, Eat healthy etc.)
• 4. Many Large Studies: No Increased Risk
Thousands of patients followed for Decades
UNINFORMED FEAR BILLROTH II
EDUCATED USE BILLROTH II
• 5. Endoscopic screening of Billroth II patients is Not
Recommended. Why? Low Risk!
• 6. General, Trauma and Oncologic surgeons routinely
use the Billroth II (Thousands of publications)
• 7. 2007 ~16,000 BII procedures were performed in the
USA
UNINFORMED FEAR BILLROTH II
EDUCATED USE BILLROTH II
• 8. Billroth II and the Mini-Gastric Bypass
Excellent, Safe and Effective
• 9. FEAR Gastric Cancer?
Avoid ETOH, Tobacco, Processed & Preserved Meats,
Rx H. Pylori,
Eat Fruits and Veggies, Yogurt and Drink Green Tea
• A Billroth II probably makes NO difference
T: TRADEOFFS
• Rational Review of the Data vs.
Fear Gastric Cancer / Bile Reflux
• Rational Thinking vs. Reptilian Brain
T: TRADEOFFS: Rational Data Analysis vs.
Irrational FEAR Gastric Cancer
• 1. Gastric Cancer Declining Rapidly
• 2. GC Environmental Causes; Easily Prevented
• 3. Some studies show Small Increased Risk
Probably from Ulcers / H. Pylori
• 4. Many large studies: NO increased risk
• 5. Endoscopic Screening: Not Recommended
• 6. General, Trauma & Oncologic Surgeons Use Billroth II
T: TRADEOFFS
FEAR OF GASTRIC CANCER
• FEAR gastric cancer?
• Avoid: Alcohol, Tobacco, Processed & Preserved
Meats
Rx: H. Pylori,
Eat Fruits & Veggies, Yogurt and
Drink Green Tea
• Billroth II Probably Makes NO DifferenceBillroth II Probably Makes NO Difference
Bariatric Surgery Rx Type 2 Diabetes
Bariatric Surgery Has Been shown to Successfully
Treat Type 2 Diabetes Mellitus
Unfortunately Failure of Bariatric Procedures Rx of
T2D is reported
Operations to be considered: Band/Sleeve/RNY
vs MGB
Bariatric Surgeons Should Not Forget Their General
Surgery Training
• Bariatric Surgeons should Learn from
General Surgery
• General Surgery and T2D
• Results of General Surgery for Gastric
Disease
• Cancer / Ulcer
Laparoscopic Mini Gastric Bypass
Cesare Peraglie MD FACS FASCRS
CLOS-Florida: Heart of Florida Regional Medical Center.
Davenport, Florida
drperaglie@gmail.com
SECO 2012
BARCELONA SPAIN
Laparoscopic-Mini Gastric Bypass: HOFRMC
•Over 1000 Laparoscopic MGB’s have been performed at HOFRMC since 2005.
•TYPICAL DEMOGRAPHICS: AGE: 45 (14-72), BMI: 45 (30-75), ~27% DIABETIC, ~50% HTN, ~31%
PREVIOUS ABDOMINAL SURGERY
•OUTCOMES
OP-TIME: 62Min. (37-186), Conversion to open: 0
LOS: 1 DAY or less (88%), 2 DAY (10%), 3 DAY (~2%), 4+ DAY
(<1%)
Re-admission: 5% (23 hour obs. PONV in all but one) / 0.8%
90 day
Leak: 0.3%
MORTALITY: 0 (HOSPITAL), 0 (PERI-OP:90D)
RNY & Small Bowel Obstruction
Every Testbook in General Surgery
Warns of SBO after RNY
RNY Causes Bowel Obstruction and Death
• My family member had
RNY=>SBO=>
Death
• RNY SBO 2-16%
• NO Other Bariatric Surgery
Has Such High Rate of
Bowel Obstruction
Some RNY Surgeons Never See Bowel Obstruction
after RNY
How Can this Be?
Poor Follow Up
Makes Good Results
RNY SBO 2-16%
RNY Surgeons Leave SBO to be
Cleaned Up by General Surgeons
Every
General Surgeon
is Now Taught
To Look For,
Be Vigilant and
Fear
Bowel Obstruction
After RNY
Gastric Bypass
Poor Follow Up
Makes Good Results
My Family Member
Who DIED
From Small Bowel Obstruction After RNY
Was Operated Upon by a
GENERAL Surgeon not a Bariatric Surgeon!
Her RNY Surgeon Does Not Know of her Death or her
Bowel Obstruction
Mini-Gastric Bypass
By Every Important Measure the
Best Choice for Rx Type 2 DM
Compared to RNY: Efficacy/Safety
One of the Highest Efficacy of Rx T2D
Highest Safety
Lowest Death Rate
Lowest Leak Rate
Lowest Early Complication Rate
Lowest Major Complication Rate
Lowest Bleeding Rate
Lowest Re-operation Rate
Lowest PE Rate
By Every Measure and in Every Study
Lap RNY Gastric Bypass
Med Coll Va.
Postoperative Complications L-RNY
Leak 4.5%
SBO 2%
PE 1%
Death 0.7%
Ann Surg. 2004 May; 239(5): 698–703. Multivariate Analysis of Risk Factors for
Death Following Gastric Bypass for Treatment of Morbid Obesity, Adolfo Z.
Fernandez, Jr, MD et al.
Lap RNY Gastric Bypass
Med Coll Va.
Postoperative Complications L-RNY
Leak 4.5%
SBO 2%
PE 1%
Death 0.7%
Ann Surg. 2004 May; 239(5): 698–703. Multivariate Analysis of Risk Factors for
Death Following Gastric Bypass for Treatment of Morbid Obesity, Adolfo Z.
Fernandez, Jr, MD et al.
Patient Satisfaction
Kular Hospital Community Hospital No Advertisement: Offer
Sleeve, RNY or MGB
Patients are followed
Sleeve pts frequently complain of N/V and referr fewer pats for
operation
RNY Less satisfaction poor referral discouraged
MGB high satisfied and refer many patients
NOW 90% of cases are MGB
India Turns to the Sleeve
Band has come and gone
Many RNY programs
Centers across India turning to sleeve for the same
reasond
Selecting an Operative Procedure
Safety and Effectiveness
Personal Experience, Animal Models, Expert Judgment,
Published Data and Controlled Prospective Randomized
Trials all show:
MGB is More Effective than Sleeve RNY
MGB is Safer than SleeveRNY
Mini-Gastric Bypass:
Excellent Results from Multiple
Surgeons
6,385 Consecutive Mini-Gastric Bypasses:
16 Years Later (Rutledge)
6,385 patients who underwent MGB from September 1997 to June
2011
Mean operative time 41 minutes and
median length of stay 1 day
Early complications occurred in 4.9%.
44 (0.7%) patients had anastomotic leaks.
Three (0.05%) patients presented with dypepsia/bile reflux not
responsive to medical therapy and were successfully treated by
Braun side-to-side jejuno-jejunostomy.
6,385 Consecutive Mini-Gastric Bypasses:
16 Years Later (Rutledge)
Gastritis/dyspepsia/marginal ulcer was the most serious long term
complication; routinely treated medically.
Excessive weight loss occurred in 1% of patients; treated by take
down of the bypass.
Mean % excess weight loss (EWL) of 78%.
10 year weight regain was mean 4.9%. >50% EWL was achieved for
95% of patients at 18 months and for 92% at 60 months.
6% of patient had inadequate weight loss or significant weight regain
were treated by revision, (addition of ~2 meters to the bypass).
Remember!
All Medical and Surgery Can Fail!
Bariatric Surgery Procedures are Known to Fail
Therefore
ALWAYS CHOOSE
Operation that Can Be Revised Safely!!
NEVER CHOOSE
Operation Revision is Dangerous!
Revision of MGB: Easily Done Rarely Needed
Revisional Surgery For Laparoscopic
Mini-Gastric Bypass
Wei-Jei Lee, M.D., Ph.D. , Yi-Chih Lee, Ph.D., Kong-
Han Ser, M.D., Shu-Chun Chen, R.N.,
Jung-Chien Chen, M.D., Yen-How Su, M.D.
Surgery for Obesity and Related Diseases
Volume 7, Issue 4 , Pages 486-491, July 2011
Revision of MGB: Easily Done Rarely Needed
January 2001 to December 2009, 1322 patients
excess weight loss and mean body mass index at 5 years after
LMGB was 72.1% and 27.1 ± 4.6 kg/m2.
Of the 1322 patients, 23 (1.7%) had undergone revision surgery
during a follow-up of 9 years.
The causes of revision
Malnutrition (Excess Weight Loss) in 9 cases
Inadequate weight loss in 8
Intractable bile reflux 3 out of 1,322 cases,
No patients had surgery for Internal hernia
FIRST International Consensus Conference on
Mini-Gastric Bypass
Paris in October 2012.
The IFSO-EC Mini-Gastric Bypass
Postgraduate Course in Barcelona in April 2012
was a notable success
• As you may know we had a great slate of presenters included such
experts and leaders included
• Prof Jean-Marc Chevallier, France, Prof Roberto Tacchino,Italy, Prof.
Dr. Manuel Garcia-Caballero, Spain, Dr. Jean Mouiel,France, Dr. Rui
Ribeiro, Dr. Cesare Peraglie, M.D., F.A.C.S., USA, Dr. Mario Musella
and Dr. K S Kular M.S. from India; and others.
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Society of Mini-Gastric Bypass Surgeons
Issues (To Do) List
00. ISSUES
01. FIRST PRINCIPLES
02. NAMING/RENAMING THE MINI-GASTRIC
BYPASS
04. THE PRESENT SATE OF THE MGB
05. NATIONAL AND INTERNATIONAL
RECOGNITION OF THE MGB
06. INTERNATIONAL MGB REGISTRY
07. MENTORING PROGRAMS FOR NEW
MGB/OL SURGEONS
08. SHARING INFORMATION
09. MGB RESEARCH PLANS
10. STANDARD PRE-OP EVALUATION PROCESS
11. STANDARD PRE-OPERATIVE PERMIT
12. PREOP MANAGEMENT OF MINI-GASTRIC
BYPASS
13. ANESTHESIA MANAGEMENT OF MINI-GASTRIC
BYPASS
14. STANDARDIZED MGB OPERATIVE
PROCEDURE
15. POST OPERATIVE MGB MANAGEMENT
16. MANAGEMENT OF MGB COMPLICATIONS
17. OTHER TOPICS (COMMITTEE’S
SUGGESTIONS)
IFSO – EC Mini-Gastric Bypass Post Grad Course,
April Barcelona
The countries represented included France, Italy,
Germany, Spain, the United Kingdom, the Czech
Republic, Portugal, Egypt, United Arab Emirates, the
Netherlands and India.
We were pleased that the room was near full,
enthusiastic and educational.
As a follow up, the Society of MGB Surgeons is seeking
to survey the present opinions of surgeons about the
MGB and the other bariatric procedures.
https://www.surveymonkey.com/s/CCVote
Society of MGB Surgeons
MGB / OAGB Survey Respondents
https://www.surveymonkey.com/s/IFSO-MGB-ConsensusConference
Or Email DrR@clos.net
Society of MGB Surgeons:
Rename the Mini-Gastric Bypass?
Dr. Rutledge & Experts Around the World:
We Want to Help You!
USA 001-702-714-0011 DrR@clos.net
CONSIDERING THE MGB?
MGB IS A SUPERB SURGERY BUT…
WARNING:
“THERE ARE “TRICKS AND TRAPS”“THERE ARE “TRICKS AND TRAPS”
https://www.surveymonkey.com/s/CCVote
Or Email DrR@clos.net
MGB Survey Findings
• Low VolumeLow Volume MGB Surgeons
= Poorer Outcomes
(Not as Bad as Sleeve or RNY)
• More Leaks
• More Reflux
• More Revisions
• MoreMore Like the “Old Loop” Anatomy
• LessLess Like Antrectomy & Billroth II Anatomy
Consensus Conference on MGB; Paris Oct 2012
“TRICKS AND TRAPS” TRAINING PROGRAM
• Didactic Sessions
Talk with the Leading World Experts
• Arrange for “Hands On Surgery” Training
Scrub on cases
Assist and
Participate in MGB Surgery
• Dr Rutledge & Dr Kular and other MGB experts World
Wide
• USA 001-702-714-0011 DrR@clos.net
Irrational Illogical Thinking
Decision-Making Errors
• Confirmation Bias
(favor information that confirms preconceptions)
• Herd Behavior
(group think override rational)
• “Reptilian Brain”
Amygdala is part "impulsive," primitive system that
triggers emotional override rational thinking
https://www.surveymonkey.com/s/IFSO-MGB-ConsensusConference Or Email DrR@clos.net
PRIMITIVE RESPONSE SYSTEMS
MODIFY RISK ASSESSMENT
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THE REPTILIAN BRAIN:
EMOTION & DECISION MAKING
• Rational Logical Thinking:
Frontal Lobe
• Amygdala
Interferes with the Frontal lobe
• Primitive, Impulsive
• Irrational decision-making
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IRRATIONAL ILLOGICAL THINKING
CONFIRMATION BIAS
• Contrary Evidence =>
Maintains or strengthens
present beliefs
• Overconfidence
in present beliefs
• Poor Decision Making
• Especially Present in
Organizations, Military, Political & Social Groups
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REPTILIAN BRAIN POOR DECISIONS
FEAR LEADS TO JUDGMENT ERRORS
• Errors in Risk Assessment
• Death Airplane Crash
• Death Car Crash
• 1 in 10,000 patient / 20 years risk of
gastric cancer
• Bowel Obstruction from internal
hernia +16% in 15 months!
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Surgeons Who Fear Gastric Cancer =
Don't Know Much About Gastric Cancer
• Surgeons who say MGB = Bad, Because of the “Risk of Cancer”
• Don't know the Risk of Cancer in the General Population
• Don't know the risk of gastric cancer in Billroth II
• Don't Fear the Risk of Bowel Obstruction from internal hernia
+16% in 5 years
• Don't Fear Esophageal Cancer after Band & Sleeve
Surgeons Who Fear Gastric Cancer =
Don't Know Much About Gastric Cancer
I have recently reviewed the literature on gastric cancer and am very knowledgeable about
the risk of gastric cancer
Question Answer
H. Pylori Treatment Normalizes Risk of Gastric
Cancer in Ulcer Patients.
Agree 100%
The association between H pylori infection and
the development of gastric cancer is well
established
Agree 100%
Gastric cancer can be prevented by treating H.
Pylori, eating a diet of fresh fruit and vegetables
and avoiding smoking, alcohol and nitrates in
preserved foods
Agree 100%
Question Answer
There are many large scale studies that show no
increased risk of gastric cancer after Billroth II:
Disagree 60% !!!
Unoperated Gastric Ulcer patients have double the risk
for Gastric Cancer
Agree 100%
There are some studies showing a slight increased risk
of gastric cancer 20-30 years after Billroth II. But these
patients had the Billroth II overwhelmingly for Ulcer
Disease &
Ulcer and Gastric Cancer have a common etiology; H.
Pylori.
Agree 100%
SURGERY
HISTORY OF POOR
DECISIONS
JOSEPH LISTER:
AMERICAN SURGEONS
DELAYED ADOPTION OF
ANTISEPSIS 10 YEARS
REPTILIAN BRAIN
POOR DECISION MAKING
• Lister
published
antisepsis
paper:
• 1867
Dr. Gross; Gross Clinic 1875
(Un) Popularity of the MGB
• Confusion:
MGB Not Old Mason Loop Gastric Bypass
• MGB = Antrectomy and BII
• Old Mason Loop =
Total Gastrectomy + BII
https://www.surveymonkey.com/s/IFSO-MGB-ConsensusConference
Or Email DrR@clos.net
PR.O.A.C.T METHODOLOGY
• Pr: Define the Problem
• O: Objectives: Criteria for Success
• A: Alternatives: Available Options
• C: Consequences: Outcomes/Results
• T: Tradeoffs: Weigh Pros & Cons
• Different Systematic way to make decisions....
https://www.surveymonkey.com/s/IFSO-MGB-ConsensusConference
Or Email DrR@clos.net
PR: STATE THE PROBLEM
• Obesity Epidemic
• History of Failure of Bariatric Surgical
Procedures
• Selecting the “Ideal / BEST”
Bariatric Surgical Procedure
https://www.surveymonkey.com/s/IFSO-MGB-ConsensusConference
Or Email DrR@clos.net
PR: Problem Definition:
Bariatric Surgery: A HISTORY OF FAILURE
Procedure Assessment
Jejuno-ileal Bypass (Failure)
Vertical Banded Gastroplasty (Failure)
Lap Band (Fail?)
RNY Bypass (Fail?)
BPD/DS (Fail?)
Sleeve: 1-5% Leaks, 60-80% Late GE Reflux,
Irreversible, High Rate Weight regain (Fail?)
Sleeve Consensus Meeting?
19 surgeons have shared their data and consensus has
been sought on specific points related to sleeve only
Mean 12% acid reflux
Many showing 20% reflux
Many showing 40 % weight loss failure
( < 50 % EWL )
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SUCCESS CRITERIA
"IDEAL" WEIGHT LOSS SURGERY
1. Low Risk
2. Major Weight Loss
3. Easily performed
4. Short operative times
5. Outpatient or short hospital stay
6. Minimal Blood Loss
7. No Need for ICU Stay
8. Minimal Pain
9. Very High Patient Satisfaction
10. A Good "Exit Strategy"
O: OBJECTIVES, SUCCESS CRITERIA
"IDEAL" WEIGHT LOSS SURGERY
O: OBJECTIVES, SUCCESS CRITERIA
"IDEAL" WEIGHT LOSS SURGERY
11. Change Behavior & Preferences; Marked Decrease in Hunger
and Increased Satiety
12. Minimal Retching and Vomiting
13. Few adhesions or hernias
14. Minimal impact on Heart and Lung Function
15. Low Failure Rate
16. Low Cost
17. Short Recovery Time
18. Rapid Return to Work
19. Low Risk of Pulmonary Embolus
20. Durable weight loss
O: OBJECTIVES, SUCCESS CRITERIA
"IDEAL" WEIGHT LOSS SURGERY
21. Low Risk of Ulcer
22. Fat Malabsorbtion; low cholesterol & CV risk
23. No Plastic Foreign Body
24. Easily Verifiable Results; > 10 years of Results
25. Low Risk of Bowel Obstruction
26. Based upon sound surgical principles
27. Independent confirmation of results
28. Healthy life after surgery
29. Supported by LEVEL I Evidence; RCT (Controlled Prospective
Randomized Trial)
30. Block “Sweet Eater” Failures
A: ALTERNATIVES
• RNY
• Band
• Sleeve
• MGB
https://www.surveymonkey.com/s/IFSO-MGB-ConsensusConference
Or Email DrR@clos.net
MINI-GASTRIC BYPASS
• The Mini-Gastric Bypass
1997 – 2011 ; >6,000 pts,
10 yr Data; Multiple Centers,
R.C.Trials
• Vertical Gastric Tube
(Collis Gastroplasty)
• Gastric Bypass
(Billroth II Gastro-jejunostomy)
https://www.surveymonkey.com/s/IFSO-MGB-ConsensusConference
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MINI-GASTRIC BYPASS
BASED SOUND SURGICAL PRACTICE
• Billroth II Performed
over 100 years
• 16,000 Billroth II’s
USA in 2007
• Operation of choice:
Trauma, Ulcers, Cancer
Stomach etc.
T: TRADEOFFS
• Fear of Gastric Cancer  Bile Reflux
• Rational vs. Reptilian Brain Decision Making
STATISTICAL ILLITERACY;
"MANY DOCTORS MISUNDERSTAND MEDICAL LITERATURE"
• Example:
“In the absence of a Roux limb,
the long-term effects of chronic alkaline reflux are unknown.”
• REALLY? Rational vs. Reptilian Brain thinking
• Billroth II >100 years and >1,450 papers on Billroth II
Collins BJ, Miyashita T, Schweitzer M, Magnuson T, Harmon JW.,
Gastric Bypass; Why Roux-en-Y? A Review of Experimental Data,
Arch Surg. 2007; 142(10):1000-1003.
STATISTICAL ILLITERACY;
"MANY DOCTORS MISUNDERSTAND MEDICAL LITERATURE"
• Example:
“In the absence of a Roux limb,
the long-term effects of chronic alkaline reflux are unknown.”
Collins BJ, Miyashita T, Schweitzer M, Magnuson T, Harmon JW.,
Gastric Bypass; Why Roux-en-Y? A Review of Experimental Data,
Arch Surg. 2007; 142(10):1000-1003.
GASTRIC CANCER
RAPIDLY DECLINING
• The incidence of gastric cancer
in the United States has
• Decreased four-fold since
1930
• Approximately 7 cases per
100,000 people.
https://www.surveymonkey.com/s/IFSO-MGB-ConsensusConference
Or Email DrR@clos.net
BARIATRIC SURGEONS FEAR BILLROTH II;
CANCER SURGEONS CHOOSE BILLROTH II
• 1,490 articles on performance of the Billroth II
• General/Trauma/Oncologic surgeons commonly use the
Billroth II
• Over 16,000 Billroth II operation
performed in USA 2007
• While Bariatric Surgeons Fear the Billroth II General
Surgeons use the Billroth II routinely
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BARIATRIC SURGEONS FEAR BILLROTH II
WHAT IS MAGNITUDE OF THE PROBLEM
• Mayo Clinic Study (Example)
• 338 Billroth II patients
• Followed 25-years
• 5,635 person-years
• Only 2 Cancers in 5,000+ pt years of Follow Up
• Schafer et al, Risk of gastric carcinoma after treatment for benign ulcer disease. N
Engl J Med. 1983 Nov 17;309
BARIATRIC SURGEONS FEAR BILLROTH II
MAGNITUDE OF THE PROBLEM
• Population based study, 338 Billroth II pts
• Followed 25-years
• 5,635 person-years
• Only 2 Cancers Found in 5,000 years
• Predicted 2.6 cancers (relative risk 0.8)
Schafer et al, Risk of gastric carcinoma after treatment for benign ulcer disease. N Engl J Med. 1983 Nov 17;309
BARIATRIC SURGEONS FEAR BILLROTH II
MAGNITUDE OF THE PROBLEM
• 338 Billroth II pts, Followed 25-years
• 5,635 person-years
• Only 2 Cancers in 5,000 pt years follow up
• RATE of Gastric Cancer is Declining
• 24 - 50% Expected Decrease from 1983
• Future risk ~1 patient / 5,000 pt years
ULCERS INCREASE RISK CANCER
• Meta-analysis:
7 studies Small increased risk
5 studies No Increased Risk
• Studies with increased Risk; Flawed
• Billroth II = Surgery Rx Ulcers
• ULCERS increase risk of Gastric Cancer!
• Ulcers and Gastric Cancer Common Etiology
=H. Pylori=
ULCERS INCREASE RISK CANCER
•3,078 gastric cancer vs. 89,082 controls
•Ulcer increases risk gastric cancer
=(relative risk 1.53)=
•Same as Increased Risk reported Billroth II
•Many other studies confirm these findings:
•Ulcer Increases Risk Gastric Cancer
•Ulcers & Gastric Cancer:
•Common Etiology =H. Pylori=
BARIATRIC SURGEONS FEAR BILLROTH II
GASTROENTEROLOGISTS IGNORE BILLROTH II
• Hundreds of thousands of people with Billroth II’s
• If cancer IS SUCH A BIG RISK…
• Shouldn’t gastroenterologists be looking for these people,
screening them with endoscopy?
• No, there is no recommendation for BII follow up screening;
Why? THE RISK IS LOW
• 63,000 yrs Follow up 23 cancers = Gen Pop.
RISK OF GASTRIC CANCER AFTER 
BILLROTH II IS LOW
• Follow-up study of 1000 patients
• 22-30 year follow-up
• 196 endoscopy and biopsy No Cancer of the gastric
remnant seen
• Endoscopic screening will be “unrewarding”
• Br J Surg. 1983 Sep;70(9):552-4. Risk of gastric cancer after Billroth II resection for
duodenal ulcer. Fischer AB
WHAT CAUSES GASTRIC CANCER?
ITS NOT BILLROTH II
• Diets rich in fried, salted, smoked or preserved foods increased cancer
risk in many studies.
• Foods contain nitrites and these chemicals can be converted to more
harmful compounds (carcinogens) by bacteria in the stomach.
• Diets high in fruit and vegetables protects against Cancer
• Stomach cancer is much more common in smokers and in those with
heavy alcohol intake.
• H. Pylori, No H. Pylori No Cancer
DIET AND CANCER PREVENTION
• Avoid ETOH, Tobacco,
Processed & Preserved
Meats, Salt
• RX H. Pylori,
• Eat Fruits and Veggies,
Yogurt and
• Drink Green Tea
•
Gonzalez CA, Cancer Research, Institut Català d'Oncologia, Av. Gran Via s/n, km
2.7, 08907 L'Hospitalet, Barcelona, Spain.
T: TRADEOFFS
FEAR OF GASTRIC CANCER
A Billroth II Probably
Makes No Difference
T: TRADEOFFS
FEAR OF GASTRIC CANCER
A Billroth II Probably Makes No
Difference
Expert Opinions: "May be the Best Operation, I
Use It Frequently"
Good, maybe the best form of WLS, I use it often?
May I beg your indulgence: Please consider giving us your learned opinion:
https://www.surveymonkey.com/s/IFSO-MGB-ConsensusConference Or Email DrR@clos.net
Expert Opinion:
Operation Judged Short and Simple
Expert Opinion:
Failure is "VERY RARE"
Experts Who Once Used the Band and Now Have
Stopped Using the Band (38%)
Expert Opinions:
Patients Routinely Get Major Weight Loss
Expert Opinions:
Patients RARELY Regain Their Weight
Expert Opinion:
Patients RARELY Suffer Long Term Complications
MGB Experts (>100 MGBs):
Patients RARELY Suffer Long Term Complications
Expert Opinions:
Procedure Advocates Reporting "No Leaks"
Expert Opinions:
Procedure Advocates Reporting a Leak
Expert Opinion:
Revision is Relatively Easy
RNY Band SG MGB
1. Low Risk - + - +
2. Major Weight Loss + - - ++
3. Easily performed - - + + +
4. Short operative times - + + +
5. Short hospital stay - - + + +
6. Minimal Blood Loss - + + +
7. No Need for ICU Stay - + + +
8. Minimal Pain - + + +
9. High Patient Satisfaction - - - +
10. A Good "Exit Strategy" - - - + - - +
RNY Band Sleeve MGB
11. Decrease Hunger + - + +
12. Min Vomiting + + + +
13. No Internal hernias - + + +
14. Min Heart/Lung - + + +
15. Low Failure Rate - - - +
16. Low Cost - - - +
17. Short Recovery - + + +
18. Return to Work - + + +
19. Low Risk of PE - + + +
20. Durable Weight Loss - - - +
RNY Band SG MGB
21. Low Risk of Ulcer - + + -
22. Malabsorption of fat + - - +
23. No Foreign Body + - + +
24. Verifiable Results - - - ++
25. Bowel Obstruction - - + + ++
26. Sound Surgical + - + +
27. Independent confirm - - - ++
28. Healthy life - - - ++
29. RCT; LEVEL I Evidence - - - ++
30. Block Sweet Eater + - - ++
CONCLUSIONS: PR.O.A.C.T.
Rational Choice: Mini-Gastric Bypass
• Pr: Choice of Obesity Surgery
• O: Objectives “Ideal” Weight Loss Surgery
• A: RNY, Band, Sleeve, MGB
• C: MGB meets almost all objectives/success criteria
• T: Fear of Bile Reflux & Gastric Cancer
Not Supported by the Data
• Rational Decision Making: Best Choice;
Mini-Gastric Bypass
WHY CRITICS ONLY CARE FOR MGB?
• Why do Critics only care about the
Mini-Gastric Bypass?
• 100,000’s of people already have and are living with and
are getting the Billroth II every day
• Why haven’t concerned bariatric surgeons stepped
forward to stop all general, trauma and oncologic
surgeons from performing this Billroth II surgery?
WHY CRITICS ONLY CARE FOR MGB?
•Why do Critics only care about the
Mini-Gastric Bypass?
•Why haven’t concerned bariatric surgeons stepped
forward to start a fund to help suffering Billroth II patients
get needed conversions of their surgery
to Roux-en-Y?
•Why don’t they write letters to the editor calling for the
Billroth II to be declared a operation non-grata?
WHY CRITICS ONLY CARE FOR MGB?
• Why do Critics only care about the
Mini-Gastric Bypass?
• Why haven’t concerned bariatric surgeons stepped
forward to national funding for lifetime endoscopic
screening of Billroth II patients to find dreaded gastric
cancers?
• It seems odd doesn’t it?
• There is a simple reason
WHY CRITICS ONLY CARE FOR MGB?
• There is a simple reason
• The critics of the MGB do not do those things because
they are ...
• Such actions are Not supported by the data
• The Billroth II and the MGB are both good operations
• Published data Does Not support the critics misreading of
the medical literature
THE TIDE BEGINS TO TURN
TO THE MINI-GASTRIC BYPASS
• “Not too long ago, the bariatric community questioned the role of the
mini-gastric bypass and its appropriateness as a durable operation for
obesity.”
• The experience of Lee et al. with a large cohort suggests some
answers.”
• Michel M. Murr, M.D.
• “The Journal continues to commit to open, spirited, and balanced
discussions that are supported by data and withstand the test of
common sense.”
• Editorial: Revisional surgery for laparoscopic mini-gastric bypass.
Lee WJ, Surg Obes Relat Dis. 2011 Jul-Aug;7(4):486-91
Mini-Gastric Bypass:
9 YEARS LATER! OUT PERFORMS RNY
• New results of the MGB:
• “1,322 patients, 23 (1.7%) had revision
Follow-up of 9 years.”
• Excess weight loss 72.1%
• No patient had surgery for internal hernia
Revisional surgery for laparoscopic mini-gastric bypass.
Lee WJ, Surg Obes Relat Dis. 2011 Jul-Aug;7(4):486-91
Patient Survey:
MGB OUT-PERFORMS BAND & RNY
• Follow up survey of bariatric surgery results in 1,500
patients’ friends, family and acquaintances
• Patient Reported Success in Friends Family:
36% RNY,
24% Band and
93% MGB
EXAMPLE FEAR & DECISION MAKING
SBO VS. GASTRIC CANCER
• Which is more Deadly?
• Gastric Cancer or Small
Bowel Obstruction?
• Which is more
fearsome?
11+ RNY STUDIES INTERNAL HERNIA BOWEL
OBSTRUCTION
• 1 - 16% Internal Hernia /Small Bowel Obstruction
• Follow Up 1-10 years (only 7% at 10 years)
• Note: Dead patients cannot return for follow up
• =15/18 patients, ReOp, failed closure USA=
DEATH AFTER
SMALL BOWEL OBSTRUCTION
• 877 patients who underwent 1,007 operations for
SBO from 1961 to 1995
• Risk of bowel obstruction increases over time
• 52 Deaths 6% Death Rate
• Ann Surg. 2000 April; 231(4), Complications and Death After Surgical Treatment of
Small Bowel Obstruction A 35-Year Institutional Experience Fevang et.al.,
Department of Surgery, University Hospital, University of Bergen, Norway
FEAR AND DECISION MAKING
SBO VS. GASTRIC CANCER
• Which is more Deadly?
• Gastric Cancer or
Small Bowel
Obstruction?
• Which is more
fearsome?
FEAR AND DECISION MAKING
SBO VS. GASTRIC CANCER
• 1,000 RNYs, Estimate 20% SBO => 200 operations for
SBO in 5-10 years (? How many more for 20 years?)
FEAR?
SBO VS. GASTRIC CANCER
• 1,000 RNYs, 20% SBO => 200 operations for SBO in
5-10 years (? How many for 20 years?)
• 6% Death Rate => 12 dead before the end of 10 years
from SBO
FEAR?
SBO VS. GASTRIC CANCER
• 1,000 RNYs, 20% SBO => 200 operations for SBO in
5-10 years (? How many for 20 years?)
• 6% Death Rate => 12 dead before the end of 10 years
from SBO
• 1,000 MGBs After 20 years possibly increased risk of
cancer of 1 / 1,000
FEAR?
SBO VS. GASTRIC CANCER
• 1,000 RNYs, 20% SBO => 200 operations for SBO in
5-10 years (? How many for 20 years?)
• 6% Death Rate => 12 dead before the end of 10 years
from SBO
• 1,000 MGBs After 20 years possibly increased risk of
cancer of 1/1,000
• Deaths at 10 years from Gastric Cancer 0.0
FEAR?
SBO VS. GASTRIC CANCER
• 1,000 RNYs, 20% SBO => 200 operations for SBO in 5-10
years (? How many for 20 years?)
• 6% Death Rate => 12 dead before the end of 10 years
from SBO
• 1,000 MGBs After 20 years possibly increased risk of
cancer of 1/1,000
• Death at 10 years from Gastric Cancer 0.0
• Death SBO 12/10 years, Deaths Gastric Cancer 10-20
years 0-1
WHICH DO YOU FEAR?
SBO VS. GASTRIC CANCER
• 1,000 RNYs = 200 SBO operations
• Death from RNY SBO 12 deaths / 10 years
• 1,000 MGB’s 0-1 Gastric Cancer @ 20 yrs
• Deaths Gastric Cancer 10-20 years 0-1?
FEAR AND DECISION MAKING
SBO VS. GASTRIC CANCER
• Which is more Deadly?
• Gastric Cancer or
Small Bowel
Obstruction?
• Which is more
fearsome?
FOLLOW UP EFFECT
• Unbiased Population based studies => Poor Results of RNY
• Positive Results of RNY reported from RNY centers
• Suffer from “Follow Up Effect”
• Patient Returns to clinic doing well: Greeted Warmly with Great Joy
• Patient Returns to clinic doing poorly: Greeted with anger and disapproval
• Successful pt => Good Follow Up / Failed pt tacitly sent away
• Now; Center reports excellent results; (30%) follow up
• Weight Regain, Band Erosion, Death
• Not Seen, Not Reported

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The Mini-Gastric Bypass:Best Treatment Type 2 Diabetes Mellitus

  • 1. The Mini-Gastric Bypass:The Mini-Gastric Bypass: Best Treatment Type 2 DiabetesBest Treatment Type 2 Diabetes MellitusMellitus Dr K S Kular Kular Medical Education & Research Society , Kular Group of Institutes , drkskular@gmail.com www.kularhospital.com
  • 2. Best Rx for Diabetes 5 Objectives 1. Consider Band/Sleeve/RNY/MGB 2. Best Rx DM Requires Gastric Procedure + Duodenal Bypass 3. Eliminates Band/Sleeve; Choice RNY vs MGB 4. RNY Most Technically Difficult Dangerous & Deadly form of Bariatric Surgery 5. Data MGB One of the Most Effective & Safest Rx for DM
  • 4. Objective 2: Best Treatment of Diabetes Includes Both a Gastric Procedure + Duodenal Bypass Data from General Surgery, Bariatric Reports, Animal Studies
  • 5. Objective 2: Animal Models Confirm Duodenal Bypass Improves Effectiveness “This study shows that bypassing Duodenum Improves T2D, independently of food intake, body weight, malabsorption, or nutrient delivery” The Mechanism of Diabetes Control After Gastrointestinal Bypass Surgery Reveals a Role of the Proximal Small Intestine in the Pathophysiology of Type 2 Diabetes. Rubino,); Marescaux, Jacques MD, FRCS Annals of Surgery; 244 (5): 741-749, November 2006
  • 6. Objective 2: Billroth I vs Billroth II Gastrectomy vs Gastrectomy + Bypass Primary Gastric Procedure (PGP) Vs Combined Gastric + Bypass (CGB) Which Leads to Greater Weight Loss? Which Leads to Greater Resolution of Diabetes? General Surgery Answer:
  • 7. Bariatric Surgeons Should Not Forget Their General Surgery Training GS for Gastric Disease (Ca/Ulcer) Gastrectomy ALONE 50% Gastrectomy + Duodenal Bypass 75% Rx T2D MUST Include Duodenal Bypass for BEST short and long term Efficacy G.O. Less Effective G+D G.O.=Gastric Only vs G+D=Gastric + Duodenal
  • 8. Outcome after gastrectomy in gastric cancer patients with type 2 diabetes • 403 gastric cancer patients with T2DM • BMI % Reduction • Duodenal Bypass: • BI: No Bypass 7.6% • BII: Bypass 11.4% • ** 50% Improvement ** • Jong Won Kim, etal, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul 135- 720, South Korea, World J Gastroenterol. 2012 January 7; 18(1): 49–54.
  • 9. Objective 2: General Surgery "Effect of Gastrectomy For  Stomach Cancer on Type 2 Diabetes Mellitus" Kang KC, Shin SH, Lee YJ, Heo YS. J Korean Surg Soc. 2012 Jun;82(6):347-55. Department of Surgery, Inha University Hospital, Inha University School of Medicine, Incheon, Korea.
  • 10. Objective 2: Gastrectomy for stomach  cancer on type 2 diabetes (Kang) 75 GCa Pts, 35 month FU BI vs BII Rx DM Gastrectomy ALONE (i.e. Sleeve) 0% Resolved, 45% improved Gastrectomy + BII (i.e. MGB) 22% Resolved, 85% Improved
  • 11. Objective 2: General Surgery J Gastrointest Surg. 2012Jan;16(1):45-51 Gastrointestinal metabolic surgery for the treatment of diabetic patients: a multi- institutional international study. Lee WJ, Hur KY, Lakadawala M, Kasama K, Wong SK, Lee YC.
  • 12. Gastrointestinal metabolic surgery for the treatment of diabetic patients (Lakadawala) 200 patients, Gastric Bypass vs Sleeve gastrectomy Remission of T2DM “Gastric Bypass pts (Gastric + Bypass) lost more weight & higher diabetes remission Sleeve pts“ Bypass pts mix of MGB/RNY (per Dr. Lee)
  • 13. Objective 2: MGB vs Sleeve Mini-Gastric bypass vs Sleeve Gastrectomy for type 2 diabetes mellitus: a Randomized Controlled TrialRandomized Controlled Trial Lee WJ, Chong K, Ser KH, Lee YC, Chen SC, Chen JC, Tsai MH, Chuang LM. Arch Surg. 2011 Feb
  • 14. Objective 2: Lee MGB vs Sleeve Randomized Controlled Trial Randomized controlled trial 60 moderately obese patients (body mass index >25 and <35) Outcome was remission of T2DM (fasting glucose <126 mg/dL and HbA(1c) <6.5% without glycemic therapy) All completed the 12-month follow-up
  • 15. Lee MGB vs Sleeve Randomized Controlled Trial Remission of Diabetes ** 93% ** Mini-gastric bypass ** 47% ** Sleeve gastrectomy (P = .02)
  • 16. Lee MGB vs Sleeve Randomized Controlled Trial Mini-gastric bypass lost more weight, achieved a lower waist circumference, and Lower glucose, HbA(1c), and blood lipid levels than the sleeve gastrectomy group
  • 17. Effectiveness of Bariatric Procedures Gastric + Duodenal Bypass Outperforms Gastric Alone G.O. Band Poor G.O. Sleeve Med High G+D RNY High G+D MGB High - Highest Conclusions Band & Sleeve Less Effective than RNY & MGB
  • 18. Objective 3: Best Rx DM Gastric Procedure + Duodenal Bypass This Excludes Band/Sleeve Need for Gastric Procedure +Bypass Eliminates Band/Sleeve; Leaves Choice RNY vs MGB
  • 19. Objective 4: RNY is the most Technically Difficult, Dangerous & Deadly form of Bariatric Surgery 100s Refs One Recent Example
  • 20. RNY is the MOST Dangerous Form of Bariatric Surgery By Every measure, in Every study RNY Highest Death Rate, Highest Leak Rate Highest Early ComplicationsHighest Major Complication Rate Highest Bleeding Rate, Highest Re-operation Rate Highest PE Rate.... RNY is the most dangerous form of Bariatric Surgery References 25-100 Studies
  • 21. RNY: Long learning curve of 500 cases RNY technically challenging 2,281 cases 1999 - 2011 Complications Stabilized after *500* cases Mortality rate .43%, main causes of death PE & Leaks (.14% each) Op time & Complications significantly reduced after a long learning curve of 500 cases Surg Obes Relat Dis. 2013 Feb 11. Overcoming the learning curve of laparoscopic Roux-en-Y gastric bypass: A 12- year experience. El-Kadre L, Tinoco AC, Tinoco RC, Aguiar L, Santos T. Department of Surgery, São José do Avaí Hospital, Itaperuna, Rio de Janeiro, Brazil.
  • 22. Lap RNY Gastric Bypass Med Coll Va. Postoperative Complications L-RNY Leak 4.5% SBO 2% PE 1% Death 0.7% Ann Surg. 2004 May; 239(5): 698–703. Multivariate Analysis of Risk Factors for Death Following Gastric Bypass for Treatment of Morbid Obesity, Adolfo Z. Fernandez, Jr, MD et al.
  • 23. RNY Bypass Surgery for Diabetes With Nonmorbid Obesity? Maybe Jun 04, 2013 Controlled Prospective Rndomized 12-months, 49% RNY pts vs 19% lifestyle pts met primary end points BUT 37% serious complications in the RNY group 2 most serious complications were anastomotic leak 3.3%!!, 1 patient suffered anoxic brain injury. Patients who underwent surgery were also more likely to have nonserious adverse events such as nutritional deficiencies. JAMA. 2013 Jun 5;309(21):Roux-en-Y gastric bypass vs intensive medical management for the control of type 2 diabetes, hypertension, and hyperlipidemia: the Diabetes Surgery Study randomized clinical trial. Ikramuddin S, Department of Surgery, School of Public Health, University of Minnesota, Minneapolis, MN 55455, USA. ikram001@umn.edu
  • 24. RNY Bypass Surgery for Diabetes Controlled Prospective Randomized Trial Normal HgbA1C level range from 4.5 to 6 Only 44% RNY pts HgbA1c < 6 (Cure) BUT 37% serious complications in the RNY group 3.3% anastomotic leaks 1 patient suffered anoxic brain injury. JAMA. 2013 Jun 5;309(21):Roux-en-Y gastric bypass vs intensive medical management for the control of type 2 diabetes, hypertension, and hyperlipidemia: the Diabetes Surgery Study randomized clinical trial. Ikramuddin S, Department of Surgery, School of Public Health, University of Minnesota, Minneapolis, MN 55455, USA. ikram001@umn.edu
  • 25. 1 yr RNY Did Not Reach Normal HgbA1c JAMA. 2013 Jun 5;309(21):Roux-en-Y gastric bypass vs intensive medical management for the control of type 2 diabetes, hypertension, and hyperlipidemia: the Diabetes Surgery Study randomized clinical trial. Ikramuddin S, Department of Surgery, School of Public Health, University of Minnesota, Minneapolis, MN 55455, USA. ikram001@umn.edu
  • 26. First report from the American College of Surgeons Bariatric Surgery Center Network 28,000 Patients Ann Surg. 2011 Sep;254(3):410-20 Hutter MM, Schirmer BD, Jones DB, Ko CY, Cohen ME, Merkow RP, Nguyen NT. Department of Surgery, Massachusetts General Hospital, Boston, MA 02114, USA.
  • 27. American College of Surgeons Bariatric Surgery Center Network Outcome SG N (%) RNY N (%) Conv to Open 9 (0.10) 207 (1.43) 30-day Mortality 1 (0.11) 21 (0.14) 1-Year Mortality 2 (0.21) 49 (0.34) Readmission 51 (5.4) 937 (6.47) Reoperation 28 (2.97) 728 (5.02) First report from the American College of Surgeons Bariatric Surgery Center Network28,000 Patients
  • 28. American College of Surgeons Bariatric Surgery Center Network Outcome LSG N (%) RNY N (%) Coma 0 2 (0.01) Stroke 0 5 (0.03) Cardiac Arrest 0 13 (0.09) Myocard Infarct 0 9 (0.06) DVT 1 (0.11) 21 (0.14) Pneumonia 3 (0.32) 58 (0.40)
  • 29. American College of Surgeons Bariatric Surgery Center Network Outcome SG N (%) RNY N (%) Intubation 3 (0.3) 59 (0.41) Ventilator (> 48 hrs) 0 55 (0.38) Acute Renal Failure 0 22 (0.15) UTI 5 (0.5) 104 (0.7) Wound Dehiscence 0 27 (0.19) Septic Shock 0 21 (0.14)
  • 30. Controlled Prospective Randomized Trial Lee WJ, Yu P-J, Wang W, Chen TC, Wei PL, Huang MT. Laparoscopic Roux-en-Y versus Mini-Gastric Bypass for the treatment of Morbid Obesity. Ann Surg 2005 ; 242 : 20-28 RYG Bypass Mini Bypass Op time (mns) 205 148 Early complications 20% 7.5% Late complications 7.5% 7.5 % EWL at one year 58.7% 64.9% EWL at two years 60% 64.4%
  • 31. Objective 5: MGB One of the Most Effective & Safest Best Rx for DM
  • 32. Objective 5: MGB One of the Most Effective & Safest MGB Series Rutledge U.S.A. 6,000 + (16 yr + FU) Lee Taiwan 1000 + (RCT, 10 yr+ FU) Noun Lebanon 1000 Kular India 1000+ Cady France 2000 + Peraglie U.S.A. 2000 + Carbajo Spain 2000 + Garcia-Caballero Spain 1000 + Musella et al. Italy 1000 Otheres (i.e. Chevallier Paris , Tacchino Rome etc.)
  • 33. MGB One of the Most Effective & Safest MGB Series Findings in all series are the same: Short operation, low risk of short and long term complications Excellent short and long term weight loss 75-100% EWL, Better than BPD) Revisable and Reversible Minimal Risk of Bile Reflux in Knowledgeable Hands
  • 34. One Thousand Consecutive Mini-gastric Bypass: Short- And Long-term Outcome 1,000 patients who underwent MGB from November 2005 to January 2011 Operative time and length of stay for primary vs. revisional MGB were 89 ± 12.8 min vs. 144 ± 15 min (p < 0.01) and l.85 ± 0.8 day vs. 2.35 ± 1.89 day (p < 0.01) Short-term complications 2.7% for primary vs. 11.6% for revisionnal MGB (p < 0.01) Obes Surg. 2012 May;22(5):697-703. One thousand consecutive mini-gastric bypass: short- and long-term outcome. Noun et al, Department of Digestive Surgery, Hôtel-Dieu de France Hospital and University Saint Joseph Medical School, Bd Alfred Naccache, Achrafieh, BP 166830 Beirut, Lebanon. rnoun@wise.net.lb
  • 35. One Thousand Consecutive Mini-gastric Bypass: Short- And Long-term Outcome Five (0.5%) patients presented with leakage from the gastic tube but none had anastomotic leakage. Four (0.4%) patients, all revisions with severe bile reflux Rx by stapled latero-lateral jejunojejunostomy (Braun). Excessive weight loss occurred in four patientseasily revised. Percent excess weight loss (EWL) of 72.5% occurred at 18 months. Obes Surg. 2012 May;22(5):697-703. One thousand consecutive mini-gastric bypass: short- and long-term outcome. Noun et al, Department of Digestive Surgery, Hôtel-Dieu de France Hospital and University Saint Joseph Medical School, Bd Alfred Naccache, Achrafieh, BP 166830 Beirut, Lebanon. rnoun@wise.net.lb
  • 36. One Thousand Consecutive Mini-gastric Bypass: Short- And Long-term Outcome The 50% EWL was achieved for 95% of patients at 18 months and for 89.8% at 60 months. MGB is an effective, relatively low-risk, and low-failure bariatric procedure. In addition, it can be easily revised, converted, or reversed. Obes Surg. 2012 May;22(5):697-703. One thousand consecutive mini-gastric bypass: short- and long-term outcome. Noun et al, Department of Digestive Surgery, Hôtel-Dieu de France Hospital and University Saint Joseph Medical School, Bd Alfred Naccache, Achrafieh, BP 166830 Beirut, Lebanon. rnoun@wise.net.lb
  • 37. Laparoscopic Roux-en-y Vs. Mini-gastric Bypass For The Treatment Of Morbid Obesity: A 10-year Experience. Obes Surg. 2012 Dec;22(12):1827-34. Laparoscopic Roux-en-Y Vs. mini-gastric bypass for the treatment of morbid obesity: a 10- year experience. Lee WJ, Ser KH, Lee YC, Tsou JJ, Chen SC, Chen JC. Department of Surgery, Min-Sheng General Hospital, National Taiwan University, No. 168, Chin Kuo Road, Tauoyan, Taiwan, Republic of China. wjlee_obessurg_tw@yahoo.com.tw
  • 38. Laparoscopic Roux-en-y Vs. Mini-gastric Bypass For The Treatment Of Morbid Obesity: A 10-year Experience. October 2001 and September 2010, 1,657 patients who received gastric bypass surgery (1,163 for LMGB and 494 for LRYGB) Surgical time was significantly longer for LRYGB (159.2 vs. 115.3 min for LMGB, p<0.001).    The major complication rate was higher for LRYGB (3.2 vs. 1.8%, p  =0.07).  5 years after surgery, the mean BMI was lower in LMGB than LRYGB (27.7 vs. 29.2, p<0.05) and    LMGB also had a higher excess weight loss than LRYGB (72.9 vs. 60.1%, p<0.05).    Late revision rate was LRYGB 3.6% and MGB 2.8%
  • 39. Laparoscopic Roux-en-y Vs. Mini-gastric Bypass For The Treatment Of Morbid Obesity: A 10-year Experience. CONCLUSIONS: This study demonstrates that MGB can be regarded as a SIMPLER and SAFER alternative to RNY with similar or BETTER efficacy at a 10- year experience.
  • 40. Surgery Can Successfully Treat Obesity and Diabetes in Both Thin and Obese Diabetic Patients • 2013: Kular Hospital • 6 year study T2DM patients • Results: • Type 2 Diabetes resolved • 98% of MGB
  • 41. MGB More Effective than BPD Dr Tacchino MGB vs BPD Weight Loss and Diabetes Resolution Following Mini- Gastric Bypass and Bilio-Pancreatic Diversion. Tacchino R., Rutledge R., Università Cattolica del Sacro Cuore, Rome, Italy 408 pts Jan 2007 to Dec 2009 36 months follow-up Mini-Gastric Bypass (n = 164) initial BMI 46.4±9.6 or Bilio-Pancreatic Diversion (n = 244) initial BMI 46.9±7 (Tacchino’s perferred Operation)
  • 42. MGB More Effective than BPD Dr Tacchino MGB vs BPD RESULTS: Mean BMI at two years was 28.5±3.9 kg/m2 and at three years 27.4±4.5 kg/m2 after MGB BMI at two years 32.7± 6.04 kg/ m2 and at three years 33.6±5.1 kg/m2 after BPD One year resolution of diabetes was accomplished in: 100% in MGB group 95% in BPD group.
  • 43. MGB More Effective than BPD Dr Tacchino MGB vs BPD Tacchino’s conclusions: “Both MGB and BPD resluted in excellent weight loss, excellent resolution of co-morbities with low risk of long term complications. The MGB was associated with greater weight loss than BPD. Improvements in other cardiovascular risk factors and quality of life were similar after both procedures.”
  • 44. Randomized Controlled Prospective Trials MGB MUCH Superior to RNY Rx Diabetes MGB vs RNY Rx Diabetes, Two Controlled Prospective Randomized Trials Ikramuddin S, et al. Roux-en-Y gastric bypass vs intensive medical management for the control of type 2 diabetes, hypertension, and hyperlipidemia: the Diabetes Surgery Study randomized clinical trial. JAMA. 2013 Jun Lee WJ, et al. Gastric bypass vs sleeve gastrectomy for type 2 diabetes mellitus: a randomized controlled trial. Arch Surg. 2011 Feb Resolution of Diabetes at 12 months Sleeve 47% RNY 44% MGB 93%
  • 45. Conclusions: MGB Best Rx for DM 1. Band/Sleeve/RNY/MGB 2. Animal, Gen Surg and Bariatric Data: Best Rx = Gastric + Duodenal Bypass 3. Excludes Band/Sleeve 4. RNY Unquestionably the Most Dangerous form of Bariatric Surgery 5. Numerous studies show MGB short safe and highly effective; Best Choice
  • 46. Which Is More DeadlyWhich Is More Deadly A Hot Dog Or A Billroth II?A Hot Dog Or A Billroth II?
  • 47. Which Is More Deadly A Hot Dog Or A Billroth II? Processed meats (Bacon, sausage, hot dogs, sandwich meat, packaged ham, pepperoni, salami, etc.) Shown to be associated with gastric cancer. An increase intake of 100 g of processed meat per day Increases the risk of Gastric Cancer by 3.5 times = Natl Cancer Inst. 2006 Mar 1;98(5):345-54. Meat intake and risk of stomach and esophageal adenocarcinoma within the European Prospective Investigation Into Cancer and Nutrition (EPIC). = J Natl Cancer Inst. 2006 2;98(15):1078 "Processed meat consumption and stomach cancer risk: a meta-analysis" The Karolinska Institutet (Hint: A Hot Dog weight 3.7 oz = 100 g = INCREASED RISK 3.5!)
  • 48. Which is more deadly a Hot Dog or a Billroth II? AA BB https://www.surveymonkey.com/s/IFSO-MGB-ConsensusConference Or Email DrR@clos.net
  • 49. Which is more deadly a Hot Dog or a Billroth II?
  • 50. Which Do Bariatric Surgeons Fear More? A Hot Dog or a Billroth II? AA BB https://www.surveymonkey.com/s/IFSO-MGB-ConsensusConference Or Email DrR@clos.net
  • 51. UNINFORMED FEAR BILLROTH II EDUCATED USE BILLROTH II • 1. Gastric Cancer Declining Rapidly, > 50% • 2. Gastric Cancer Cause: Environmental Factors / Easily Prevented Diet, Lifestyle changes and Rx of H. Pylori (Avoid Etoh, smoking, processed & salted meats and foods, seek high intake of fruits and vegetables)
  • 52. UNINFORMED FEAR BILLROTH II EDUCATED USE BILLROTH II • 3. Some studies Slight Increased Risk of gastric cancer after 20 – 30 years (RR 1.5): But: BII was performed to Rx Ulcer => Ulcer => Increased Risk • (Worried? Rx H Pylori, Eat healthy etc.) • 4. Many Large Studies: No Increased Risk Thousands of patients followed for Decades
  • 53. UNINFORMED FEAR BILLROTH II EDUCATED USE BILLROTH II • 5. Endoscopic screening of Billroth II patients is Not Recommended. Why? Low Risk! • 6. General, Trauma and Oncologic surgeons routinely use the Billroth II (Thousands of publications) • 7. 2007 ~16,000 BII procedures were performed in the USA
  • 54. UNINFORMED FEAR BILLROTH II EDUCATED USE BILLROTH II • 8. Billroth II and the Mini-Gastric Bypass Excellent, Safe and Effective • 9. FEAR Gastric Cancer? Avoid ETOH, Tobacco, Processed & Preserved Meats, Rx H. Pylori, Eat Fruits and Veggies, Yogurt and Drink Green Tea • A Billroth II probably makes NO difference
  • 55. T: TRADEOFFS • Rational Review of the Data vs. Fear Gastric Cancer / Bile Reflux • Rational Thinking vs. Reptilian Brain
  • 56. T: TRADEOFFS: Rational Data Analysis vs. Irrational FEAR Gastric Cancer • 1. Gastric Cancer Declining Rapidly • 2. GC Environmental Causes; Easily Prevented • 3. Some studies show Small Increased Risk Probably from Ulcers / H. Pylori • 4. Many large studies: NO increased risk • 5. Endoscopic Screening: Not Recommended • 6. General, Trauma & Oncologic Surgeons Use Billroth II
  • 57. T: TRADEOFFS FEAR OF GASTRIC CANCER • FEAR gastric cancer? • Avoid: Alcohol, Tobacco, Processed & Preserved Meats Rx: H. Pylori, Eat Fruits & Veggies, Yogurt and Drink Green Tea • Billroth II Probably Makes NO DifferenceBillroth II Probably Makes NO Difference
  • 58. Bariatric Surgery Rx Type 2 Diabetes Bariatric Surgery Has Been shown to Successfully Treat Type 2 Diabetes Mellitus Unfortunately Failure of Bariatric Procedures Rx of T2D is reported Operations to be considered: Band/Sleeve/RNY vs MGB
  • 59. Bariatric Surgeons Should Not Forget Their General Surgery Training • Bariatric Surgeons should Learn from General Surgery • General Surgery and T2D • Results of General Surgery for Gastric Disease • Cancer / Ulcer
  • 60. Laparoscopic Mini Gastric Bypass Cesare Peraglie MD FACS FASCRS CLOS-Florida: Heart of Florida Regional Medical Center. Davenport, Florida drperaglie@gmail.com SECO 2012 BARCELONA SPAIN
  • 61. Laparoscopic-Mini Gastric Bypass: HOFRMC •Over 1000 Laparoscopic MGB’s have been performed at HOFRMC since 2005. •TYPICAL DEMOGRAPHICS: AGE: 45 (14-72), BMI: 45 (30-75), ~27% DIABETIC, ~50% HTN, ~31% PREVIOUS ABDOMINAL SURGERY •OUTCOMES OP-TIME: 62Min. (37-186), Conversion to open: 0 LOS: 1 DAY or less (88%), 2 DAY (10%), 3 DAY (~2%), 4+ DAY (<1%) Re-admission: 5% (23 hour obs. PONV in all but one) / 0.8% 90 day Leak: 0.3% MORTALITY: 0 (HOSPITAL), 0 (PERI-OP:90D)
  • 62. RNY & Small Bowel Obstruction
  • 63.
  • 64. Every Testbook in General Surgery Warns of SBO after RNY
  • 65. RNY Causes Bowel Obstruction and Death • My family member had RNY=>SBO=> Death • RNY SBO 2-16% • NO Other Bariatric Surgery Has Such High Rate of Bowel Obstruction
  • 66. Some RNY Surgeons Never See Bowel Obstruction after RNY How Can this Be? Poor Follow Up Makes Good Results RNY SBO 2-16%
  • 67. RNY Surgeons Leave SBO to be Cleaned Up by General Surgeons Every General Surgeon is Now Taught To Look For, Be Vigilant and Fear Bowel Obstruction After RNY Gastric Bypass
  • 68. Poor Follow Up Makes Good Results My Family Member Who DIED From Small Bowel Obstruction After RNY Was Operated Upon by a GENERAL Surgeon not a Bariatric Surgeon! Her RNY Surgeon Does Not Know of her Death or her Bowel Obstruction
  • 69. Mini-Gastric Bypass By Every Important Measure the Best Choice for Rx Type 2 DM Compared to RNY: Efficacy/Safety One of the Highest Efficacy of Rx T2D Highest Safety Lowest Death Rate Lowest Leak Rate Lowest Early Complication Rate Lowest Major Complication Rate Lowest Bleeding Rate Lowest Re-operation Rate Lowest PE Rate By Every Measure and in Every Study
  • 70. Lap RNY Gastric Bypass Med Coll Va. Postoperative Complications L-RNY Leak 4.5% SBO 2% PE 1% Death 0.7% Ann Surg. 2004 May; 239(5): 698–703. Multivariate Analysis of Risk Factors for Death Following Gastric Bypass for Treatment of Morbid Obesity, Adolfo Z. Fernandez, Jr, MD et al.
  • 71. Lap RNY Gastric Bypass Med Coll Va. Postoperative Complications L-RNY Leak 4.5% SBO 2% PE 1% Death 0.7% Ann Surg. 2004 May; 239(5): 698–703. Multivariate Analysis of Risk Factors for Death Following Gastric Bypass for Treatment of Morbid Obesity, Adolfo Z. Fernandez, Jr, MD et al.
  • 72. Patient Satisfaction Kular Hospital Community Hospital No Advertisement: Offer Sleeve, RNY or MGB Patients are followed Sleeve pts frequently complain of N/V and referr fewer pats for operation RNY Less satisfaction poor referral discouraged MGB high satisfied and refer many patients NOW 90% of cases are MGB
  • 73. India Turns to the Sleeve Band has come and gone Many RNY programs Centers across India turning to sleeve for the same reasond
  • 74. Selecting an Operative Procedure Safety and Effectiveness Personal Experience, Animal Models, Expert Judgment, Published Data and Controlled Prospective Randomized Trials all show: MGB is More Effective than Sleeve RNY MGB is Safer than SleeveRNY
  • 75. Mini-Gastric Bypass: Excellent Results from Multiple Surgeons
  • 76. 6,385 Consecutive Mini-Gastric Bypasses: 16 Years Later (Rutledge) 6,385 patients who underwent MGB from September 1997 to June 2011 Mean operative time 41 minutes and median length of stay 1 day Early complications occurred in 4.9%. 44 (0.7%) patients had anastomotic leaks. Three (0.05%) patients presented with dypepsia/bile reflux not responsive to medical therapy and were successfully treated by Braun side-to-side jejuno-jejunostomy.
  • 77. 6,385 Consecutive Mini-Gastric Bypasses: 16 Years Later (Rutledge) Gastritis/dyspepsia/marginal ulcer was the most serious long term complication; routinely treated medically. Excessive weight loss occurred in 1% of patients; treated by take down of the bypass. Mean % excess weight loss (EWL) of 78%. 10 year weight regain was mean 4.9%. >50% EWL was achieved for 95% of patients at 18 months and for 92% at 60 months. 6% of patient had inadequate weight loss or significant weight regain were treated by revision, (addition of ~2 meters to the bypass).
  • 78. Remember! All Medical and Surgery Can Fail! Bariatric Surgery Procedures are Known to Fail Therefore ALWAYS CHOOSE Operation that Can Be Revised Safely!! NEVER CHOOSE Operation Revision is Dangerous!
  • 79. Revision of MGB: Easily Done Rarely Needed Revisional Surgery For Laparoscopic Mini-Gastric Bypass Wei-Jei Lee, M.D., Ph.D. , Yi-Chih Lee, Ph.D., Kong- Han Ser, M.D., Shu-Chun Chen, R.N., Jung-Chien Chen, M.D., Yen-How Su, M.D. Surgery for Obesity and Related Diseases Volume 7, Issue 4 , Pages 486-491, July 2011
  • 80. Revision of MGB: Easily Done Rarely Needed January 2001 to December 2009, 1322 patients excess weight loss and mean body mass index at 5 years after LMGB was 72.1% and 27.1 ± 4.6 kg/m2. Of the 1322 patients, 23 (1.7%) had undergone revision surgery during a follow-up of 9 years. The causes of revision Malnutrition (Excess Weight Loss) in 9 cases Inadequate weight loss in 8 Intractable bile reflux 3 out of 1,322 cases, No patients had surgery for Internal hernia
  • 81. FIRST International Consensus Conference on Mini-Gastric Bypass Paris in October 2012.
  • 82. The IFSO-EC Mini-Gastric Bypass Postgraduate Course in Barcelona in April 2012 was a notable success • As you may know we had a great slate of presenters included such experts and leaders included • Prof Jean-Marc Chevallier, France, Prof Roberto Tacchino,Italy, Prof. Dr. Manuel Garcia-Caballero, Spain, Dr. Jean Mouiel,France, Dr. Rui Ribeiro, Dr. Cesare Peraglie, M.D., F.A.C.S., USA, Dr. Mario Musella and Dr. K S Kular M.S. from India; and others. https://www.surveymonkey.com/s/CCVote Or Email DrR@clos.net
  • 83. Society of Mini-Gastric Bypass Surgeons Issues (To Do) List 00. ISSUES 01. FIRST PRINCIPLES 02. NAMING/RENAMING THE MINI-GASTRIC BYPASS 04. THE PRESENT SATE OF THE MGB 05. NATIONAL AND INTERNATIONAL RECOGNITION OF THE MGB 06. INTERNATIONAL MGB REGISTRY 07. MENTORING PROGRAMS FOR NEW MGB/OL SURGEONS 08. SHARING INFORMATION 09. MGB RESEARCH PLANS 10. STANDARD PRE-OP EVALUATION PROCESS 11. STANDARD PRE-OPERATIVE PERMIT 12. PREOP MANAGEMENT OF MINI-GASTRIC BYPASS 13. ANESTHESIA MANAGEMENT OF MINI-GASTRIC BYPASS 14. STANDARDIZED MGB OPERATIVE PROCEDURE 15. POST OPERATIVE MGB MANAGEMENT 16. MANAGEMENT OF MGB COMPLICATIONS 17. OTHER TOPICS (COMMITTEE’S SUGGESTIONS)
  • 84. IFSO – EC Mini-Gastric Bypass Post Grad Course, April Barcelona The countries represented included France, Italy, Germany, Spain, the United Kingdom, the Czech Republic, Portugal, Egypt, United Arab Emirates, the Netherlands and India. We were pleased that the room was near full, enthusiastic and educational. As a follow up, the Society of MGB Surgeons is seeking to survey the present opinions of surgeons about the MGB and the other bariatric procedures. https://www.surveymonkey.com/s/CCVote
  • 85. Society of MGB Surgeons MGB / OAGB Survey Respondents https://www.surveymonkey.com/s/IFSO-MGB-ConsensusConference Or Email DrR@clos.net
  • 86. Society of MGB Surgeons: Rename the Mini-Gastric Bypass?
  • 87. Dr. Rutledge & Experts Around the World: We Want to Help You! USA 001-702-714-0011 DrR@clos.net CONSIDERING THE MGB? MGB IS A SUPERB SURGERY BUT… WARNING: “THERE ARE “TRICKS AND TRAPS”“THERE ARE “TRICKS AND TRAPS” https://www.surveymonkey.com/s/CCVote Or Email DrR@clos.net
  • 88. MGB Survey Findings • Low VolumeLow Volume MGB Surgeons = Poorer Outcomes (Not as Bad as Sleeve or RNY) • More Leaks • More Reflux • More Revisions • MoreMore Like the “Old Loop” Anatomy • LessLess Like Antrectomy & Billroth II Anatomy
  • 89. Consensus Conference on MGB; Paris Oct 2012 “TRICKS AND TRAPS” TRAINING PROGRAM • Didactic Sessions Talk with the Leading World Experts • Arrange for “Hands On Surgery” Training Scrub on cases Assist and Participate in MGB Surgery • Dr Rutledge & Dr Kular and other MGB experts World Wide • USA 001-702-714-0011 DrR@clos.net
  • 90. Irrational Illogical Thinking Decision-Making Errors • Confirmation Bias (favor information that confirms preconceptions) • Herd Behavior (group think override rational) • “Reptilian Brain” Amygdala is part "impulsive," primitive system that triggers emotional override rational thinking https://www.surveymonkey.com/s/IFSO-MGB-ConsensusConference Or Email DrR@clos.net
  • 91. PRIMITIVE RESPONSE SYSTEMS MODIFY RISK ASSESSMENT https://www.surveymonkey.com/s/CCVote Or Email DrR@clos.net
  • 92. THE REPTILIAN BRAIN: EMOTION & DECISION MAKING • Rational Logical Thinking: Frontal Lobe • Amygdala Interferes with the Frontal lobe • Primitive, Impulsive • Irrational decision-making https://www.surveymonkey.com/s/CCVote Or Email DrR@clos.net
  • 93. IRRATIONAL ILLOGICAL THINKING CONFIRMATION BIAS • Contrary Evidence => Maintains or strengthens present beliefs • Overconfidence in present beliefs • Poor Decision Making • Especially Present in Organizations, Military, Political & Social Groups https://www.surveymonkey.com/s/CCVote Or Email DrR@clos.net
  • 94. REPTILIAN BRAIN POOR DECISIONS FEAR LEADS TO JUDGMENT ERRORS • Errors in Risk Assessment • Death Airplane Crash • Death Car Crash • 1 in 10,000 patient / 20 years risk of gastric cancer • Bowel Obstruction from internal hernia +16% in 15 months! https://www.surveymonkey.com/s/CCVote Or Email DrR@clos.net
  • 95. Surgeons Who Fear Gastric Cancer = Don't Know Much About Gastric Cancer • Surgeons who say MGB = Bad, Because of the “Risk of Cancer” • Don't know the Risk of Cancer in the General Population • Don't know the risk of gastric cancer in Billroth II • Don't Fear the Risk of Bowel Obstruction from internal hernia +16% in 5 years • Don't Fear Esophageal Cancer after Band & Sleeve
  • 96. Surgeons Who Fear Gastric Cancer = Don't Know Much About Gastric Cancer I have recently reviewed the literature on gastric cancer and am very knowledgeable about the risk of gastric cancer
  • 97. Question Answer H. Pylori Treatment Normalizes Risk of Gastric Cancer in Ulcer Patients. Agree 100% The association between H pylori infection and the development of gastric cancer is well established Agree 100% Gastric cancer can be prevented by treating H. Pylori, eating a diet of fresh fruit and vegetables and avoiding smoking, alcohol and nitrates in preserved foods Agree 100%
  • 98. Question Answer There are many large scale studies that show no increased risk of gastric cancer after Billroth II: Disagree 60% !!! Unoperated Gastric Ulcer patients have double the risk for Gastric Cancer Agree 100% There are some studies showing a slight increased risk of gastric cancer 20-30 years after Billroth II. But these patients had the Billroth II overwhelmingly for Ulcer Disease & Ulcer and Gastric Cancer have a common etiology; H. Pylori. Agree 100%
  • 99. SURGERY HISTORY OF POOR DECISIONS JOSEPH LISTER: AMERICAN SURGEONS DELAYED ADOPTION OF ANTISEPSIS 10 YEARS
  • 100. REPTILIAN BRAIN POOR DECISION MAKING • Lister published antisepsis paper: • 1867 Dr. Gross; Gross Clinic 1875
  • 101. (Un) Popularity of the MGB • Confusion: MGB Not Old Mason Loop Gastric Bypass • MGB = Antrectomy and BII • Old Mason Loop = Total Gastrectomy + BII https://www.surveymonkey.com/s/IFSO-MGB-ConsensusConference Or Email DrR@clos.net
  • 102. PR.O.A.C.T METHODOLOGY • Pr: Define the Problem • O: Objectives: Criteria for Success • A: Alternatives: Available Options • C: Consequences: Outcomes/Results • T: Tradeoffs: Weigh Pros & Cons • Different Systematic way to make decisions.... https://www.surveymonkey.com/s/IFSO-MGB-ConsensusConference Or Email DrR@clos.net
  • 103. PR: STATE THE PROBLEM • Obesity Epidemic • History of Failure of Bariatric Surgical Procedures • Selecting the “Ideal / BEST” Bariatric Surgical Procedure https://www.surveymonkey.com/s/IFSO-MGB-ConsensusConference Or Email DrR@clos.net
  • 104. PR: Problem Definition: Bariatric Surgery: A HISTORY OF FAILURE Procedure Assessment Jejuno-ileal Bypass (Failure) Vertical Banded Gastroplasty (Failure) Lap Band (Fail?) RNY Bypass (Fail?) BPD/DS (Fail?) Sleeve: 1-5% Leaks, 60-80% Late GE Reflux, Irreversible, High Rate Weight regain (Fail?)
  • 105. Sleeve Consensus Meeting? 19 surgeons have shared their data and consensus has been sought on specific points related to sleeve only Mean 12% acid reflux Many showing 20% reflux Many showing 40 % weight loss failure ( < 50 % EWL ) https://www.surveymonkey.com/s/CCVote Or Email DrR@clos.net
  • 107. 1. Low Risk 2. Major Weight Loss 3. Easily performed 4. Short operative times 5. Outpatient or short hospital stay 6. Minimal Blood Loss 7. No Need for ICU Stay 8. Minimal Pain 9. Very High Patient Satisfaction 10. A Good "Exit Strategy" O: OBJECTIVES, SUCCESS CRITERIA "IDEAL" WEIGHT LOSS SURGERY
  • 108. O: OBJECTIVES, SUCCESS CRITERIA "IDEAL" WEIGHT LOSS SURGERY 11. Change Behavior & Preferences; Marked Decrease in Hunger and Increased Satiety 12. Minimal Retching and Vomiting 13. Few adhesions or hernias 14. Minimal impact on Heart and Lung Function 15. Low Failure Rate 16. Low Cost 17. Short Recovery Time 18. Rapid Return to Work 19. Low Risk of Pulmonary Embolus 20. Durable weight loss
  • 109. O: OBJECTIVES, SUCCESS CRITERIA "IDEAL" WEIGHT LOSS SURGERY 21. Low Risk of Ulcer 22. Fat Malabsorbtion; low cholesterol & CV risk 23. No Plastic Foreign Body 24. Easily Verifiable Results; > 10 years of Results 25. Low Risk of Bowel Obstruction 26. Based upon sound surgical principles 27. Independent confirmation of results 28. Healthy life after surgery 29. Supported by LEVEL I Evidence; RCT (Controlled Prospective Randomized Trial) 30. Block “Sweet Eater” Failures
  • 110. A: ALTERNATIVES • RNY • Band • Sleeve • MGB https://www.surveymonkey.com/s/IFSO-MGB-ConsensusConference Or Email DrR@clos.net
  • 111. MINI-GASTRIC BYPASS • The Mini-Gastric Bypass 1997 – 2011 ; >6,000 pts, 10 yr Data; Multiple Centers, R.C.Trials • Vertical Gastric Tube (Collis Gastroplasty) • Gastric Bypass (Billroth II Gastro-jejunostomy) https://www.surveymonkey.com/s/IFSO-MGB-ConsensusConference Or Email DrR@clos.net
  • 112. MINI-GASTRIC BYPASS BASED SOUND SURGICAL PRACTICE • Billroth II Performed over 100 years • 16,000 Billroth II’s USA in 2007 • Operation of choice: Trauma, Ulcers, Cancer Stomach etc.
  • 113. T: TRADEOFFS • Fear of Gastric Cancer Bile Reflux • Rational vs. Reptilian Brain Decision Making
  • 114. STATISTICAL ILLITERACY; "MANY DOCTORS MISUNDERSTAND MEDICAL LITERATURE" • Example: “In the absence of a Roux limb, the long-term effects of chronic alkaline reflux are unknown.” • REALLY? Rational vs. Reptilian Brain thinking • Billroth II >100 years and >1,450 papers on Billroth II Collins BJ, Miyashita T, Schweitzer M, Magnuson T, Harmon JW., Gastric Bypass; Why Roux-en-Y? A Review of Experimental Data, Arch Surg. 2007; 142(10):1000-1003.
  • 115. STATISTICAL ILLITERACY; "MANY DOCTORS MISUNDERSTAND MEDICAL LITERATURE" • Example: “In the absence of a Roux limb, the long-term effects of chronic alkaline reflux are unknown.” Collins BJ, Miyashita T, Schweitzer M, Magnuson T, Harmon JW., Gastric Bypass; Why Roux-en-Y? A Review of Experimental Data, Arch Surg. 2007; 142(10):1000-1003.
  • 116. GASTRIC CANCER RAPIDLY DECLINING • The incidence of gastric cancer in the United States has • Decreased four-fold since 1930 • Approximately 7 cases per 100,000 people. https://www.surveymonkey.com/s/IFSO-MGB-ConsensusConference Or Email DrR@clos.net
  • 117. BARIATRIC SURGEONS FEAR BILLROTH II; CANCER SURGEONS CHOOSE BILLROTH II • 1,490 articles on performance of the Billroth II • General/Trauma/Oncologic surgeons commonly use the Billroth II • Over 16,000 Billroth II operation performed in USA 2007 • While Bariatric Surgeons Fear the Billroth II General Surgeons use the Billroth II routinely https://www.surveymonkey.com/s/CCVote Or Email DrR@clos.net
  • 118. BARIATRIC SURGEONS FEAR BILLROTH II WHAT IS MAGNITUDE OF THE PROBLEM • Mayo Clinic Study (Example) • 338 Billroth II patients • Followed 25-years • 5,635 person-years • Only 2 Cancers in 5,000+ pt years of Follow Up • Schafer et al, Risk of gastric carcinoma after treatment for benign ulcer disease. N Engl J Med. 1983 Nov 17;309
  • 119. BARIATRIC SURGEONS FEAR BILLROTH II MAGNITUDE OF THE PROBLEM • Population based study, 338 Billroth II pts • Followed 25-years • 5,635 person-years • Only 2 Cancers Found in 5,000 years • Predicted 2.6 cancers (relative risk 0.8) Schafer et al, Risk of gastric carcinoma after treatment for benign ulcer disease. N Engl J Med. 1983 Nov 17;309
  • 120. BARIATRIC SURGEONS FEAR BILLROTH II MAGNITUDE OF THE PROBLEM • 338 Billroth II pts, Followed 25-years • 5,635 person-years • Only 2 Cancers in 5,000 pt years follow up • RATE of Gastric Cancer is Declining • 24 - 50% Expected Decrease from 1983 • Future risk ~1 patient / 5,000 pt years
  • 121. ULCERS INCREASE RISK CANCER • Meta-analysis: 7 studies Small increased risk 5 studies No Increased Risk • Studies with increased Risk; Flawed • Billroth II = Surgery Rx Ulcers • ULCERS increase risk of Gastric Cancer! • Ulcers and Gastric Cancer Common Etiology =H. Pylori=
  • 122. ULCERS INCREASE RISK CANCER •3,078 gastric cancer vs. 89,082 controls •Ulcer increases risk gastric cancer =(relative risk 1.53)= •Same as Increased Risk reported Billroth II •Many other studies confirm these findings: •Ulcer Increases Risk Gastric Cancer •Ulcers & Gastric Cancer: •Common Etiology =H. Pylori=
  • 123. BARIATRIC SURGEONS FEAR BILLROTH II GASTROENTEROLOGISTS IGNORE BILLROTH II • Hundreds of thousands of people with Billroth II’s • If cancer IS SUCH A BIG RISK… • Shouldn’t gastroenterologists be looking for these people, screening them with endoscopy? • No, there is no recommendation for BII follow up screening; Why? THE RISK IS LOW • 63,000 yrs Follow up 23 cancers = Gen Pop.
  • 124. RISK OF GASTRIC CANCER AFTER  BILLROTH II IS LOW • Follow-up study of 1000 patients • 22-30 year follow-up • 196 endoscopy and biopsy No Cancer of the gastric remnant seen • Endoscopic screening will be “unrewarding” • Br J Surg. 1983 Sep;70(9):552-4. Risk of gastric cancer after Billroth II resection for duodenal ulcer. Fischer AB
  • 125.
  • 126. WHAT CAUSES GASTRIC CANCER? ITS NOT BILLROTH II • Diets rich in fried, salted, smoked or preserved foods increased cancer risk in many studies. • Foods contain nitrites and these chemicals can be converted to more harmful compounds (carcinogens) by bacteria in the stomach. • Diets high in fruit and vegetables protects against Cancer • Stomach cancer is much more common in smokers and in those with heavy alcohol intake. • H. Pylori, No H. Pylori No Cancer
  • 127. DIET AND CANCER PREVENTION • Avoid ETOH, Tobacco, Processed & Preserved Meats, Salt • RX H. Pylori, • Eat Fruits and Veggies, Yogurt and • Drink Green Tea • Gonzalez CA, Cancer Research, Institut Català d'Oncologia, Av. Gran Via s/n, km 2.7, 08907 L'Hospitalet, Barcelona, Spain.
  • 128. T: TRADEOFFS FEAR OF GASTRIC CANCER A Billroth II Probably Makes No Difference
  • 129. T: TRADEOFFS FEAR OF GASTRIC CANCER A Billroth II Probably Makes No Difference
  • 130. Expert Opinions: "May be the Best Operation, I Use It Frequently" Good, maybe the best form of WLS, I use it often? May I beg your indulgence: Please consider giving us your learned opinion: https://www.surveymonkey.com/s/IFSO-MGB-ConsensusConference Or Email DrR@clos.net
  • 131. Expert Opinion: Operation Judged Short and Simple
  • 133. Experts Who Once Used the Band and Now Have Stopped Using the Band (38%)
  • 134. Expert Opinions: Patients Routinely Get Major Weight Loss
  • 135. Expert Opinions: Patients RARELY Regain Their Weight
  • 136. Expert Opinion: Patients RARELY Suffer Long Term Complications
  • 137. MGB Experts (>100 MGBs): Patients RARELY Suffer Long Term Complications
  • 138. Expert Opinions: Procedure Advocates Reporting "No Leaks"
  • 140. Expert Opinion: Revision is Relatively Easy
  • 141. RNY Band SG MGB 1. Low Risk - + - + 2. Major Weight Loss + - - ++ 3. Easily performed - - + + + 4. Short operative times - + + + 5. Short hospital stay - - + + + 6. Minimal Blood Loss - + + + 7. No Need for ICU Stay - + + + 8. Minimal Pain - + + + 9. High Patient Satisfaction - - - + 10. A Good "Exit Strategy" - - - + - - +
  • 142. RNY Band Sleeve MGB 11. Decrease Hunger + - + + 12. Min Vomiting + + + + 13. No Internal hernias - + + + 14. Min Heart/Lung - + + + 15. Low Failure Rate - - - + 16. Low Cost - - - + 17. Short Recovery - + + + 18. Return to Work - + + + 19. Low Risk of PE - + + + 20. Durable Weight Loss - - - +
  • 143. RNY Band SG MGB 21. Low Risk of Ulcer - + + - 22. Malabsorption of fat + - - + 23. No Foreign Body + - + + 24. Verifiable Results - - - ++ 25. Bowel Obstruction - - + + ++ 26. Sound Surgical + - + + 27. Independent confirm - - - ++ 28. Healthy life - - - ++ 29. RCT; LEVEL I Evidence - - - ++ 30. Block Sweet Eater + - - ++
  • 144. CONCLUSIONS: PR.O.A.C.T. Rational Choice: Mini-Gastric Bypass • Pr: Choice of Obesity Surgery • O: Objectives “Ideal” Weight Loss Surgery • A: RNY, Band, Sleeve, MGB • C: MGB meets almost all objectives/success criteria • T: Fear of Bile Reflux & Gastric Cancer Not Supported by the Data • Rational Decision Making: Best Choice; Mini-Gastric Bypass
  • 145. WHY CRITICS ONLY CARE FOR MGB? • Why do Critics only care about the Mini-Gastric Bypass? • 100,000’s of people already have and are living with and are getting the Billroth II every day • Why haven’t concerned bariatric surgeons stepped forward to stop all general, trauma and oncologic surgeons from performing this Billroth II surgery?
  • 146. WHY CRITICS ONLY CARE FOR MGB? •Why do Critics only care about the Mini-Gastric Bypass? •Why haven’t concerned bariatric surgeons stepped forward to start a fund to help suffering Billroth II patients get needed conversions of their surgery to Roux-en-Y? •Why don’t they write letters to the editor calling for the Billroth II to be declared a operation non-grata?
  • 147. WHY CRITICS ONLY CARE FOR MGB? • Why do Critics only care about the Mini-Gastric Bypass? • Why haven’t concerned bariatric surgeons stepped forward to national funding for lifetime endoscopic screening of Billroth II patients to find dreaded gastric cancers? • It seems odd doesn’t it? • There is a simple reason
  • 148. WHY CRITICS ONLY CARE FOR MGB? • There is a simple reason • The critics of the MGB do not do those things because they are ... • Such actions are Not supported by the data • The Billroth II and the MGB are both good operations • Published data Does Not support the critics misreading of the medical literature
  • 149. THE TIDE BEGINS TO TURN TO THE MINI-GASTRIC BYPASS • “Not too long ago, the bariatric community questioned the role of the mini-gastric bypass and its appropriateness as a durable operation for obesity.” • The experience of Lee et al. with a large cohort suggests some answers.” • Michel M. Murr, M.D. • “The Journal continues to commit to open, spirited, and balanced discussions that are supported by data and withstand the test of common sense.” • Editorial: Revisional surgery for laparoscopic mini-gastric bypass. Lee WJ, Surg Obes Relat Dis. 2011 Jul-Aug;7(4):486-91
  • 150. Mini-Gastric Bypass: 9 YEARS LATER! OUT PERFORMS RNY • New results of the MGB: • “1,322 patients, 23 (1.7%) had revision Follow-up of 9 years.” • Excess weight loss 72.1% • No patient had surgery for internal hernia Revisional surgery for laparoscopic mini-gastric bypass. Lee WJ, Surg Obes Relat Dis. 2011 Jul-Aug;7(4):486-91
  • 151. Patient Survey: MGB OUT-PERFORMS BAND & RNY • Follow up survey of bariatric surgery results in 1,500 patients’ friends, family and acquaintances • Patient Reported Success in Friends Family: 36% RNY, 24% Band and 93% MGB
  • 152. EXAMPLE FEAR & DECISION MAKING SBO VS. GASTRIC CANCER • Which is more Deadly? • Gastric Cancer or Small Bowel Obstruction? • Which is more fearsome?
  • 153. 11+ RNY STUDIES INTERNAL HERNIA BOWEL OBSTRUCTION • 1 - 16% Internal Hernia /Small Bowel Obstruction • Follow Up 1-10 years (only 7% at 10 years) • Note: Dead patients cannot return for follow up • =15/18 patients, ReOp, failed closure USA=
  • 154. DEATH AFTER SMALL BOWEL OBSTRUCTION • 877 patients who underwent 1,007 operations for SBO from 1961 to 1995 • Risk of bowel obstruction increases over time • 52 Deaths 6% Death Rate • Ann Surg. 2000 April; 231(4), Complications and Death After Surgical Treatment of Small Bowel Obstruction A 35-Year Institutional Experience Fevang et.al., Department of Surgery, University Hospital, University of Bergen, Norway
  • 155. FEAR AND DECISION MAKING SBO VS. GASTRIC CANCER • Which is more Deadly? • Gastric Cancer or Small Bowel Obstruction? • Which is more fearsome?
  • 156. FEAR AND DECISION MAKING SBO VS. GASTRIC CANCER • 1,000 RNYs, Estimate 20% SBO => 200 operations for SBO in 5-10 years (? How many more for 20 years?)
  • 157. FEAR? SBO VS. GASTRIC CANCER • 1,000 RNYs, 20% SBO => 200 operations for SBO in 5-10 years (? How many for 20 years?) • 6% Death Rate => 12 dead before the end of 10 years from SBO
  • 158. FEAR? SBO VS. GASTRIC CANCER • 1,000 RNYs, 20% SBO => 200 operations for SBO in 5-10 years (? How many for 20 years?) • 6% Death Rate => 12 dead before the end of 10 years from SBO • 1,000 MGBs After 20 years possibly increased risk of cancer of 1 / 1,000
  • 159. FEAR? SBO VS. GASTRIC CANCER • 1,000 RNYs, 20% SBO => 200 operations for SBO in 5-10 years (? How many for 20 years?) • 6% Death Rate => 12 dead before the end of 10 years from SBO • 1,000 MGBs After 20 years possibly increased risk of cancer of 1/1,000 • Deaths at 10 years from Gastric Cancer 0.0
  • 160. FEAR? SBO VS. GASTRIC CANCER • 1,000 RNYs, 20% SBO => 200 operations for SBO in 5-10 years (? How many for 20 years?) • 6% Death Rate => 12 dead before the end of 10 years from SBO • 1,000 MGBs After 20 years possibly increased risk of cancer of 1/1,000 • Death at 10 years from Gastric Cancer 0.0 • Death SBO 12/10 years, Deaths Gastric Cancer 10-20 years 0-1
  • 161. WHICH DO YOU FEAR? SBO VS. GASTRIC CANCER • 1,000 RNYs = 200 SBO operations • Death from RNY SBO 12 deaths / 10 years • 1,000 MGB’s 0-1 Gastric Cancer @ 20 yrs • Deaths Gastric Cancer 10-20 years 0-1?
  • 162. FEAR AND DECISION MAKING SBO VS. GASTRIC CANCER • Which is more Deadly? • Gastric Cancer or Small Bowel Obstruction? • Which is more fearsome?
  • 163. FOLLOW UP EFFECT • Unbiased Population based studies => Poor Results of RNY • Positive Results of RNY reported from RNY centers • Suffer from “Follow Up Effect” • Patient Returns to clinic doing well: Greeted Warmly with Great Joy • Patient Returns to clinic doing poorly: Greeted with anger and disapproval • Successful pt => Good Follow Up / Failed pt tacitly sent away • Now; Center reports excellent results; (30%) follow up • Weight Regain, Band Erosion, Death • Not Seen, Not Reported