5. More Rapid Discontinuation of ART in Depressed Persons Bangsberg DR et al. 41st Interscience Conference on Antimicrobial Agents and Chemotherapy; December 16-21, 2001; Chicago, Ill. Abstract 1721. BDI 15 BDI 15-censored BDI<15 BDI<15-censored Months on highly active ART 70 60 50 40 30 20 10 0 Cumulative survival 1.0 .8 .6 .4 .2 0.0 P = 0.0001
6.
7. DEFINITION OF GROUPS Himelhoch S, et al. J Acquir Immune Defic Syndr. 2004;37:1457-1463. Excluded Mental Disorder No Mental Disorder Mental Disorder Met 1 or 2 of 3 Criteria Psychiatric Diagnosis Psychiatric Medication Psychiatric Evaluation
8. ASSOCIATION BETWEEN MENTAL D/O AND TIME TO HAART TIME IN YEARS PROBABILITY OF HAART THERAPY P=0.05 No Mental Disorder Mental Disorder 2 4 6 0 Himelhoch S, et al. J Acquir Immune Defic Syndr. 2004;37:1457-1463.
9. ASSOCIATION BETWEEN MENTAL DISORDER AND SURVIVAL TIME IN YEARS PROBABILITY OF SURVIVAL No Mental Disorder Mental Disorder P=0.10 Himelhoch S, et al. J Acquir Immune Defic Syndr. 2004;37:1457-1463.
23. TIME OF AIDS DEPRESSION AS AIDS DEVELOPS MONTHS BEFORE AND AFTER AIDS P E R C E N T D E P R E S S E D 0 10 20 -48 -36 -24 -12 6 18 Lyketsos CG, et al. Am J Psychiatry. 1996;153:1430-1437.
26. 0 100 DEMENTIA SUBSTANCE USE PERSONALITY DISORDER COMPLIANT OVERALL Full Partial None Treatment of Depression Outcome by Diagnosis Lyketsos, C. G., Fishman, M., Hutton, H., Cox, T., Hobbs, S., Spoeler, C., Hunt, W., Driscoll, J., Treisman, G. J ., The effectiveness of psychiatric treatment for HIV infected patients, Psychosomatics: 1997: 38:423-432
28. CASE STUDY OF PATIENTS WITH HIV AND MANIA NEGATIVE HISTORY (N=7) 33.6 7 male 4 gay/2 IDU 6/6 all AIDS all POSITIVE HISTORY (N=7) 36.0 5 male 4 IDU/3 gay 2/7 2 AIDS/5 HIV+ none AGE SEX RISK FACTOR CD4<100 * STAGE * DEMENTIA * * p<0.05 by fisher's exact test