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Using HIV Incidence Surveillance Data
 to Examine Racial/Ethnic Disparities in
 HIV Testing Behaviors Among YMSM
        in Los Angeles County



S Nakelsky, V Hu, E Kahn, Z Sheng, L Taylor, T Bingham
           HIV Epidemiology Program
  Los Angeles County Department of Public Health
Overview
• Background
• Study population
• Methods
  – Core HIV Surveillance System
  – HIV Incidence Surveillance System
• Results
  – New HIV cases diagnosed
  – HIV testing behaviors and frequency by race/ethnicity
  – HIV incidence estimates for all MSM
• Conclusions and recommendations
Background
• CDC testing recommendations:
  – At least annual HIV testing for those at high risk


• MSM in LAC are not adhering to guidelines:
  –   Concurrent HIV and AIDS diagnoses (13%)
  –   24% diagnosed with AIDS within 6 months of HIV
  –   2008 NHBS-MSM2 data (mean= 12.1 months)
  –   New indicator: testing and treatment history data
      collected for HIV Incidence Surveillance
Why young MSM?
• The majority (~84%) of people diagnosed with
  HIV annually in LAC are MSM.
• In 2008, MSM aged 13-29 years were the
  group most frequently diagnosed with HIV.
• Identifying strategies to increase HIV
  diagnosis and to decrease transmission in
  YMSM will have a large impact on LAC’s
  epidemic.
Methods
• Data were obtained from existing HIV
  surveillance systems

• Eligibility for analysis:
   –   13-29 years of age
   –   Diagnosed in 2008
   –   Resided in LAC at the time of diagnosis
   –   Reported sex with males as a risk factor

• Denominators for rates assumed 4% of males
  aged 13-29 years were MSM
Data Sources (1)
• Enhanced HIV/AIDS Reporting System
  (EHARS)
  –   Age
  –   Race/ethnicity
  –   Mode of transmission
  –   HIV diagnosis date
  –   Proportion of cases diagnosed with AIDS within 6
      months of HIV diagnosis (late detection)
Data Sources (2)
• HIV Incidence Surveillance
  – Uses statistical methods to estimate # of new
    infections among those who do and don’t test
  – Serologic Testing Algorithm for Recent HIV
    Seroconversion (STARHS)
     • Remnant sera of new HIV diagnoses tested with BED
       assay to estimate # of cases acquiring HIV in 12 months
  – HIV testing and treatment history
     • History of previous negative test results
     • Date of most recent negative test result
     • Time between last negative and first positive test
Results from EHARS
Results: Overview of YMSM in LAC, 2008

• 563 MSM aged 13-29 years were newly
  diagnosed with HIV
• Latinos represented the largest number of new
  diagnoses among YMSM
• Rates of new HIV diagnoses:
  – 31 per 1,000 for Blacks
  – 10 per 1,000 for Whites
  – 9 per 1,000 for Latinos
Proportion of YMSM in
Los Angeles County by Race, 2008
  Total Population      New HIV Diagnoses

            Black,           Other
     Other,
            9.0%             7.8%
     12.0%
                                     Black
White,                  White        26.3%
23.1%                   21.0%
              Latino,
               55.9%            Latino
                                44.9%
Late Detection
% diagnosed with AIDS within 6 months of HIV Diagnosis

20%

15%      18.3%           17.4%
                                          15.3%
10%

5%

0%
      Black (n=148)   Latino (n=253)   White (n=118)
Results from HIS data
STARHS Results by Race
70%
                                             Recent
60%         63%
                            63%              Longterm
50%
                                       50% 50%
40%
      37%             37%
30%
20%
10%
0%
      Black (n=78)   Latino (n=116)   White (n=50)
First Time versus Repeat Testers by Race
  100%

   80%

   60%                             74%
                  87%                              89%
   40%                                                       Repeat Tester
                                                             New Tester
   20%
                                   26%
                  13%                              11%
     0%
             Black (n=82)         Latino       White(n=64)
                                 (n=151)
Latino vs. Black p=0.02; Latino vs. White p=0.01
Months between Last Negative and
                                First Positive Test by Race
                        16
Mean Number of Months




                        14
                        12                                14
                        10         13
                         8
                         6
                                                                          9
                         4
                         2
                         0
                               Black (n=70)         Latino (n=106)   White (n=56)


                 White vs. Latino p=0.02; white vs. black p=0.04
Months since Last HIV Test by Race,
                               YMSM enrolled in 2008 NHBS

                        15
Mean Number of Months




                        13
                        11
                         9        12.8        12.6
                                                          10.8
                         7
                         5
                         3
                         1
                                 Black       Latino      White
Estimated HIV Incidence Rates
                        for all MSM in LAC, 2008
                 18                                       16
                 16
                 14
                                 11
                 12
                         10               9
Rate per 1,000




                 10
                                                                   8
                  8                               7
                  6
                  4
                  2
                  0                                      Black   Latino
                         13-29   30-39   40-49   White
                                 Age                     Race


                                                                          17
Summary
• STARHS results indicate <50% of YMSM
  adhere to annual HIV testing recommendations
• Frequency of HIV testing varies by race/eth.
  – Latino YMSM reported highest:
     • Average months between last negative and first positive
     • Proportion of new HIV diagnoses at first test
  – Black YMSM reported lower testing frequency
    compared with White YMSM
• Black YMSM are disproportionately impacted
  – Findings observed in both surveillance systems
                                                                 18
Limitations
• Establishing HIS within LAC has proven
  challenging
• HIS data for 2008 are marginally complete
  – Of the men diagnosed with non-AIDS HIV, 244
    (51%) had a STARHS result available
  – 435 cases (71%) had some but not all testing
    history data elements available
Conclusions
• HIS provides additional insight for monitoring
  HIV testing behaviors and rate of new
  infections

• In LAC, all YMSM—but especially Blacks
  and Latinos—would benefit from increased
  HIV testing to detect new infections
Moving Forward
• Future research should focus on identifying
  specific barriers (e.g., stigma, access,
  acceptable modes) to HIV testing among
  YMSM

• Revised testing recommendations, social
  marketing campaigns, and other approaches
  must consider racial/ethnic differences in
  testing norms and HIV incidence rates to
  support more appropriate testing intervals
Thank You!
    For more information contact:
         Shoshanna Nakelsky
HIV Incidence Surveillance Coordinator
     snakelsky@ph.lacounty.gov
            213.351.8154



                                         22

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Using HIV Incidence Surveillance Data to Examine Racial/Ethnic Disparities in HIV Testing Behaviors Among YMSM in Los Angeles County

  • 1. Using HIV Incidence Surveillance Data to Examine Racial/Ethnic Disparities in HIV Testing Behaviors Among YMSM in Los Angeles County S Nakelsky, V Hu, E Kahn, Z Sheng, L Taylor, T Bingham HIV Epidemiology Program Los Angeles County Department of Public Health
  • 2. Overview • Background • Study population • Methods – Core HIV Surveillance System – HIV Incidence Surveillance System • Results – New HIV cases diagnosed – HIV testing behaviors and frequency by race/ethnicity – HIV incidence estimates for all MSM • Conclusions and recommendations
  • 3. Background • CDC testing recommendations: – At least annual HIV testing for those at high risk • MSM in LAC are not adhering to guidelines: – Concurrent HIV and AIDS diagnoses (13%) – 24% diagnosed with AIDS within 6 months of HIV – 2008 NHBS-MSM2 data (mean= 12.1 months) – New indicator: testing and treatment history data collected for HIV Incidence Surveillance
  • 4. Why young MSM? • The majority (~84%) of people diagnosed with HIV annually in LAC are MSM. • In 2008, MSM aged 13-29 years were the group most frequently diagnosed with HIV. • Identifying strategies to increase HIV diagnosis and to decrease transmission in YMSM will have a large impact on LAC’s epidemic.
  • 5. Methods • Data were obtained from existing HIV surveillance systems • Eligibility for analysis: – 13-29 years of age – Diagnosed in 2008 – Resided in LAC at the time of diagnosis – Reported sex with males as a risk factor • Denominators for rates assumed 4% of males aged 13-29 years were MSM
  • 6. Data Sources (1) • Enhanced HIV/AIDS Reporting System (EHARS) – Age – Race/ethnicity – Mode of transmission – HIV diagnosis date – Proportion of cases diagnosed with AIDS within 6 months of HIV diagnosis (late detection)
  • 7. Data Sources (2) • HIV Incidence Surveillance – Uses statistical methods to estimate # of new infections among those who do and don’t test – Serologic Testing Algorithm for Recent HIV Seroconversion (STARHS) • Remnant sera of new HIV diagnoses tested with BED assay to estimate # of cases acquiring HIV in 12 months – HIV testing and treatment history • History of previous negative test results • Date of most recent negative test result • Time between last negative and first positive test
  • 9. Results: Overview of YMSM in LAC, 2008 • 563 MSM aged 13-29 years were newly diagnosed with HIV • Latinos represented the largest number of new diagnoses among YMSM • Rates of new HIV diagnoses: – 31 per 1,000 for Blacks – 10 per 1,000 for Whites – 9 per 1,000 for Latinos
  • 10. Proportion of YMSM in Los Angeles County by Race, 2008 Total Population New HIV Diagnoses Black, Other Other, 9.0% 7.8% 12.0% Black White, White 26.3% 23.1% 21.0% Latino, 55.9% Latino 44.9%
  • 11. Late Detection % diagnosed with AIDS within 6 months of HIV Diagnosis 20% 15% 18.3% 17.4% 15.3% 10% 5% 0% Black (n=148) Latino (n=253) White (n=118)
  • 13. STARHS Results by Race 70% Recent 60% 63% 63% Longterm 50% 50% 50% 40% 37% 37% 30% 20% 10% 0% Black (n=78) Latino (n=116) White (n=50)
  • 14. First Time versus Repeat Testers by Race 100% 80% 60% 74% 87% 89% 40% Repeat Tester New Tester 20% 26% 13% 11% 0% Black (n=82) Latino White(n=64) (n=151) Latino vs. Black p=0.02; Latino vs. White p=0.01
  • 15. Months between Last Negative and First Positive Test by Race 16 Mean Number of Months 14 12 14 10 13 8 6 9 4 2 0 Black (n=70) Latino (n=106) White (n=56) White vs. Latino p=0.02; white vs. black p=0.04
  • 16. Months since Last HIV Test by Race, YMSM enrolled in 2008 NHBS 15 Mean Number of Months 13 11 9 12.8 12.6 10.8 7 5 3 1 Black Latino White
  • 17. Estimated HIV Incidence Rates for all MSM in LAC, 2008 18 16 16 14 11 12 10 9 Rate per 1,000 10 8 8 7 6 4 2 0 Black Latino 13-29 30-39 40-49 White Age Race 17
  • 18. Summary • STARHS results indicate <50% of YMSM adhere to annual HIV testing recommendations • Frequency of HIV testing varies by race/eth. – Latino YMSM reported highest: • Average months between last negative and first positive • Proportion of new HIV diagnoses at first test – Black YMSM reported lower testing frequency compared with White YMSM • Black YMSM are disproportionately impacted – Findings observed in both surveillance systems 18
  • 19. Limitations • Establishing HIS within LAC has proven challenging • HIS data for 2008 are marginally complete – Of the men diagnosed with non-AIDS HIV, 244 (51%) had a STARHS result available – 435 cases (71%) had some but not all testing history data elements available
  • 20. Conclusions • HIS provides additional insight for monitoring HIV testing behaviors and rate of new infections • In LAC, all YMSM—but especially Blacks and Latinos—would benefit from increased HIV testing to detect new infections
  • 21. Moving Forward • Future research should focus on identifying specific barriers (e.g., stigma, access, acceptable modes) to HIV testing among YMSM • Revised testing recommendations, social marketing campaigns, and other approaches must consider racial/ethnic differences in testing norms and HIV incidence rates to support more appropriate testing intervals
  • 22. Thank You! For more information contact: Shoshanna Nakelsky HIV Incidence Surveillance Coordinator snakelsky@ph.lacounty.gov 213.351.8154 22