Marking the 20th anniversary of World AIDS Day (December 1), this gallery shows the transition over time in how CAFOD has tackled HIV, from the early focus on care and treatment, through to the innovative, wide-ranging education, preventive and awareness work of today
2. Zimbabwe 1992: Care at an outpatients clinic at Matibi mission hospital . In 1999, Zimbabwe was named the world's most affected country, with around one-quarter of all adults living with HIV at the time
3. Uganda 1996: Showing a traditional view of AIDS at the time – a patient receiving care at the Villa Maria hospital. One of CAFOD's first AIDS programmes was in Kitovu, Uganda – first set up in 1988 and continuing today in a wide range of activities
4. Kenya 1996: An early AIDS awareness poster. Statistics released just six years later claimed there were 1.1 million children orphaned by AIDS in Kenya, and UNAIDS figures showed life expectancy had reduced by approximately 13 years to just 51 as a result of HIV. However, the numbers of people on ARVs in Kenya have doubled since 2003 as the drugs became cheaper and more widely available
5. El Salvador 1996: Campaigning for World AIDS Day. AIDS awareness came late to El Salvador, where a macho culture contributed to a high rate of infection in the 1990s. CAFOD partners challenged this by promoting behaviour change, working with teachers, prisons, parishes and parents of primary schoolchildren
6. Ethiopia 1998: A support programme for children orphaned by AIDS. Foster mum Hirut Hailu (sitting) created a new family for six orphans in a house rented by long-term CAFOD partner Medical Missionaries of Mary. Her new family are Tsghreda, Amsal, Salamawit, Yamrot, Biniyam and Hanna
7. Ghana 2002: Peer education - a dance by Youth In Action, supported by CAFOD partner CEDEP, teaching young people about issues related to HIV
8. Mozambique 2007: Celina Mader, 18, nurses her parents, who are both HIV positive, and is supported by a network of HIV activists who volunteer to stand alongside families in need
9. Cambodia 2008: Bourn Phanna, 18, (right) and his cousin Ou Khouch, 17, teaches awareness of HIV issues for children at the Happy Happy programme, through playing music. Watch a film of their music at www.cafod.org.uk/bigdeal
10. Colombia 2008: CAFOD partner ACIN works with young people and teachers from the Nasa indigenous community from Jambaló in south-west Colombia, looking at issues which can increase vulnerability to HIV, such as domestic violence, relationship problems and women's rights Read more on www.cafod.org.uk/bigdeal
11. Photography by Sean Sprague, Dario Mitidieri, Gideon Mendel, Jon Spaull, Annie Bungeroth, ACIN www.cafod.org.uk/worldaidsday