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Childrens epilepsy:
5 challenges for QS dev
Why QS 1?
Why QS 2?
Why QS 3?
Challenge 1: medication + seizure
Tegretol (carbamazepine) -> mood changes
Keppra (levitiracetam)
Depakine (valproaat) -> fat
Topamax (topiramate) -> cognitive fails
Diphantoine (Diphantoïne-Z , Epanutin, Fenytoïne) -> unhealthy
Mogadone
Trileptal (oxcarbazepine)
Frisium (clobazam)
Lamictal (lamatrogine) -> mood changes + tired + fever
Temesta -> addictive
Ospolot (sultiam)
Valium
Vimpat (lacosamide)
Seizuretracker.com
Challenge 2: Adherence
Challenge 3: nightly seizure tracking
•
•
•
•
•
•
•

Current practice: LOL!
MyZeo (sleep tracking - inpractical)
Fitbit (sleep tracking - inpractical)
Fitbit flex (sleep tracking - easy, but confusing)
Jawbone UP (sleep tracking – testing + IFTTT)
Dlink camera DCS-5020L
MyBasis + Beddit: ordered & untested
Challenge 4A: medical info
•
•
•
•
•
•
•
•
•
•

Video EEG (2011 + 2013)
EEG (… + 2013)
FDG-PET (2013)
MRI (… + 2013)
SISCOM
EEG-fMRI (2013)
Interictal EEG (2013)
Ictal SPECT (2013)
MEG (2013)
Appointments + feedback + results + notes
Challenge 4B: circumstantial info
• Food, mood, stress, …
• Overlay por favor
• Objective translation
Challenge 5: seizure alert
• Smart-monitor
• Epi care 3000
GO TO WORK!

… Oh wait …
Miscellanous Experimental info
• Neurolink has developed a drug-device combination
therapy for the treatment of epilepsy. Link
• The Neurosigma Monarch is indicated as an adjunctive
treatment of epilepsy link
• Wave’s wireless monitoring aims to manage epilepsy
link
• The Epicenter team tackled the problem of controlling
epileptic seizures through diet and biofeedback. Link
• The epilepsy detection wristband carries two kinds of
sensors link
• @bart

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5 challenges for QS in epilepsy detection

  • 5. Challenge 1: medication + seizure Tegretol (carbamazepine) -> mood changes Keppra (levitiracetam) Depakine (valproaat) -> fat Topamax (topiramate) -> cognitive fails Diphantoine (Diphantoïne-Z , Epanutin, Fenytoïne) -> unhealthy Mogadone Trileptal (oxcarbazepine) Frisium (clobazam) Lamictal (lamatrogine) -> mood changes + tired + fever Temesta -> addictive Ospolot (sultiam) Valium Vimpat (lacosamide)
  • 8. Challenge 3: nightly seizure tracking • • • • • • • Current practice: LOL! MyZeo (sleep tracking - inpractical) Fitbit (sleep tracking - inpractical) Fitbit flex (sleep tracking - easy, but confusing) Jawbone UP (sleep tracking – testing + IFTTT) Dlink camera DCS-5020L MyBasis + Beddit: ordered & untested
  • 9. Challenge 4A: medical info • • • • • • • • • • Video EEG (2011 + 2013) EEG (… + 2013) FDG-PET (2013) MRI (… + 2013) SISCOM EEG-fMRI (2013) Interictal EEG (2013) Ictal SPECT (2013) MEG (2013) Appointments + feedback + results + notes
  • 10. Challenge 4B: circumstantial info • Food, mood, stress, … • Overlay por favor • Objective translation
  • 11. Challenge 5: seizure alert • Smart-monitor • Epi care 3000
  • 12. GO TO WORK! … Oh wait …
  • 13. Miscellanous Experimental info • Neurolink has developed a drug-device combination therapy for the treatment of epilepsy. Link • The Neurosigma Monarch is indicated as an adjunctive treatment of epilepsy link • Wave’s wireless monitoring aims to manage epilepsy link • The Epicenter team tackled the problem of controlling epileptic seizures through diet and biofeedback. Link • The epilepsy detection wristband carries two kinds of sensors link • @bart