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[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Copyright   © 2010 All Rights Reserved Collaborative Drug   Discovery
CDD  aids  C ollaborations Result New leads reveal known drugs that reverse chloroquine resistance
CDD Successfully Builds  Collaborative Drug Discovery Communities ,[object Object],[object Object],[object Object],[object Object]
© 2009 Collaborative Drug Discovery, Inc.
Yes We Can! © 2010 Collaborative Drug Discovery, Inc.
[object Object],[object Object],[object Object],[object Object],[object Object],Register for GlaxoSmithKline on CDD Public Copyright   © 2010 All Rights Reserved Collaborative Drug   Discovery
Networks Selectively Collaborating  “Public-Private Partnerships” # of [compds][targets][indications][experts]  = (xyz)(pdq)(abc)(lmn)
CDD Database for Your Private Data Copyright   © 2010 All Rights Reserved Collaborative Drug   Discovery
Collaborate Mode 1 – Big Pharma   with single login to multiple CROs/Biotech groups Copyright   © 2010 All Rights Reserved Collaborative Drug   Discovery
Collaborate Mode 2 – Peer-to-Peer:  Any  Data via Any Query Can Be Securely Shared CDD DB group 1 CDD DB group 2 CDD DB group 3  CDD DB group 4 Copyright   © 2010 All Rights Reserved Collaborative Drug   Discovery
[object Object],[object Object],[object Object],[object Object],[object Object],Questions for our Field Copyright   © 2010 All Rights Reserved Collaborative Drug   Discovery
Where CDD Adds Value – Moving top Drug Leads Forward  CDD moves top leads forward Value Academics + CDD $0.1M $1M $10M $5M $0.3M Enzymatic Assays Cell Based Functional Assays Animal Efficacy Tox/PK Academic Early Drug Leads -1 yr -2 yr 2 yr Med Chem Lead Optimization 1 yr ,[object Object],Billion $ Examples: Taxol
[object Object],[object Object],[object Object],What if you could… Copyright   © 2010 All Rights Reserved Collaborative Drug   Discovery Models Inside company Collaborators Commercial Descriptors  Algorithms ADME/Tox data Current investments >$1M/yr >$10-100’s M/yr
Yes we can…predictions now  can be shared without revealing structures!
The future: Alerts in CDD
CDD Platform ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Copyright   © 2010 All Rights Reserved Collaborative Drug   Discovery
Securely Zoom in-and-out of   Private, Collaborative, and/or Public Vaults (Data)  © 2009 Collaborative Drug Discovery, Inc.
[object Object],Telescopic View of Multiple Vaults & Data Sets © 2010 Collaborative Drug Discovery, Inc.
Simultaneously Search All Vaults & Data Sets: Gets You “Outside the Box” © 2010 Collaborative Drug Discovery, Inc.
New Types of Offerings for a Rapidly Changing Industry ,[object Object],[object Object],[object Object],Use CDD Vault™, Collaborate™, Public™  for Global R&D Community
Acknowledgements Copyright   © 2010 All Rights Reserved Collaborative Drug   Discovery ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Copyright   © 2010 All Rights Reserved Collaborative Drug   Discovery Answers for Our Field
CDD   Collaborative Drug Discovery, Inc. Burlingame, CA www.collaborativedrug.com  Barry A. Bunin, PhD CEO & President  [email_address]   Archive, Mine, Collaborate ®
CDD3 Data Mapper: Intuitive Templates and Previews Simplify Archival Copyright   © 2009 All Rights Reserved Collaborative Drug   Discovery
CDD Projects – More Advanced Collaborate
Collaborative Dashboard for Secure To-the-Minute Global R&D Tracking Copyright   © 2010 All Rights Reserved Collaborative Drug   Discovery
CDD  Case Study: Create a Globally  Connected TB Researcher Community ,[object Object],[object Object],[object Object],[object Object]
CDD database system ,[object Object],[object Object],[object Object],Secure   and Low TCO (Total Cost of Ownership) Copyright   © 2010 All Rights Reserved Collaborative Drug   Discovery
CDD database system: Security overview ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Copyright   © 2010 All Rights Reserved Collaborative Drug   Discovery
Fundamentally Faster Rate of Innovation Copyright   © 2010 All Rights Reserved Collaborative Drug   Discovery
CDD Search Results View Copyright   © 2010 All Rights Reserved Collaborative Drug   Discovery
Super Simple Scatter Plots
Heat Maps, Controls, & Plate Statistics Copyright   © 2010 All Rights Reserved Collaborative Drug   Discovery

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Cdd mind the health gap 2010 talk.ppt [autosaved]

  • 1.
  • 2. CDD aids C ollaborations Result New leads reveal known drugs that reverse chloroquine resistance
  • 3.
  • 4. © 2009 Collaborative Drug Discovery, Inc.
  • 5. Yes We Can! © 2010 Collaborative Drug Discovery, Inc.
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  • 7. Networks Selectively Collaborating “Public-Private Partnerships” # of [compds][targets][indications][experts] = (xyz)(pdq)(abc)(lmn)
  • 8. CDD Database for Your Private Data Copyright © 2010 All Rights Reserved Collaborative Drug Discovery
  • 9. Collaborate Mode 1 – Big Pharma with single login to multiple CROs/Biotech groups Copyright © 2010 All Rights Reserved Collaborative Drug Discovery
  • 10. Collaborate Mode 2 – Peer-to-Peer: Any Data via Any Query Can Be Securely Shared CDD DB group 1 CDD DB group 2 CDD DB group 3 CDD DB group 4 Copyright © 2010 All Rights Reserved Collaborative Drug Discovery
  • 11.
  • 12.
  • 13.
  • 14. Yes we can…predictions now can be shared without revealing structures!
  • 16.
  • 17. Securely Zoom in-and-out of Private, Collaborative, and/or Public Vaults (Data) © 2009 Collaborative Drug Discovery, Inc.
  • 18.
  • 19. Simultaneously Search All Vaults & Data Sets: Gets You “Outside the Box” © 2010 Collaborative Drug Discovery, Inc.
  • 20.
  • 21.
  • 22.
  • 23. CDD Collaborative Drug Discovery, Inc. Burlingame, CA www.collaborativedrug.com Barry A. Bunin, PhD CEO & President [email_address] Archive, Mine, Collaborate ®
  • 24. CDD3 Data Mapper: Intuitive Templates and Previews Simplify Archival Copyright © 2009 All Rights Reserved Collaborative Drug Discovery
  • 25. CDD Projects – More Advanced Collaborate
  • 26. Collaborative Dashboard for Secure To-the-Minute Global R&D Tracking Copyright © 2010 All Rights Reserved Collaborative Drug Discovery
  • 27.
  • 28.
  • 29.
  • 30. Fundamentally Faster Rate of Innovation Copyright © 2010 All Rights Reserved Collaborative Drug Discovery
  • 31. CDD Search Results View Copyright © 2010 All Rights Reserved Collaborative Drug Discovery
  • 33. Heat Maps, Controls, & Plate Statistics Copyright © 2010 All Rights Reserved Collaborative Drug Discovery

Editor's Notes

  1. CDD Experienced Team Innovates and Executes Barry Bunin, PhD (Pres. & Cofounder as first Eli Lilly EIR) Libraria (CEO, Pres.-CSO), Arris Pharmaceuticals (Sr. Scientist), Genentech, UC Berkeley (Ellman), Columbia University, author. Moses Hohman, PhD (Director Software Engineering) Northwestern Assoc. Director of Bioinformatics, Thoughtworks, Inc., U of Chicago (PhD), Harvard ( magna cum laude, Physics) Sylvia Ernst, PhD (Director Community Growth & Sales) Left 800-lb Gorillas: Accelrys-Scitegic, MDL-Elsevier-Beilstein Peter Cohan (BOD & Overall Sales Strategy) Symyx (VP Bus Dev & President-Discovery Tools), MDL (VP Customer Marketing), www.secondderivative.com, author. Omidyar Network, Founders Fund, & Lilly (BOD observers) WSGR (Corporate Counsel), Rina Accountancy (GAAP compliance) Partners: Hub Consortium Members, ChemAxon, DNDi, MMV, Sandler Center… CDD SAB: Christopher Lipinski PhD, James McKerrow, MD PhD, David Roos PhD, Adam Renslo PhD, Wes Van Voorhis, MD PhD
  2. CDD Experienced Team Innovates and Executes Barry Bunin, PhD (Pres. & Cofounder as first Eli Lilly EIR) Libraria (CEO, Pres.-CSO), Arris Pharmaceuticals (Sr. Scientist), Genentech, UC Berkeley (Ellman), Columbia University, author. Moses Hohman, PhD (Director Software Engineering) Northwestern Assoc. Director of Bioinformatics, Thoughtworks, Inc., U of Chicago (PhD), Harvard ( magna cum laude, Physics) Sylvia Ernst, PhD (Director Community Growth & Sales) Left 800-lb Gorillas: Accelrys-Scitegic, MDL-Elsevier-Beilstein Peter Cohan (BOD & Overall Sales Strategy) Symyx (VP Bus Dev & President-Discovery Tools), MDL (VP Customer Marketing), www.secondderivative.com, author. Omidyar Network, Founders Fund, & Lilly (BOD observers) WSGR (Corporate Counsel), Rina Accountancy (GAAP compliance) Partners: Hub Consortium Members, ChemAxon, DNDi, MMV, Sandler Center… CDD SAB: Christopher Lipinski PhD, James McKerrow, MD PhD, David Roos PhD, Adam Renslo PhD, Wes Van Voorhis, MD PhD
  3. CDD Experienced Team Innovates and Executes Barry Bunin, PhD (Pres. & Cofounder as first Eli Lilly EIR) Libraria (CEO, Pres.-CSO), Arris Pharmaceuticals (Sr. Scientist), Genentech, UC Berkeley (Ellman), Columbia University, author. Moses Hohman, PhD (Director Software Engineering) Northwestern Assoc. Director of Bioinformatics, Thoughtworks, Inc., U of Chicago (PhD), Harvard ( magna cum laude, Physics) Sylvia Ernst, PhD (Director Community Growth & Sales) Left 800-lb Gorillas: Accelrys-Scitegic, MDL-Elsevier-Beilstein Peter Cohan (BOD & Overall Sales Strategy) Symyx (VP Bus Dev & President-Discovery Tools), MDL (VP Customer Marketing), www.secondderivative.com, author. Omidyar Network, Founders Fund, & Lilly (BOD observers) WSGR (Corporate Counsel), Rina Accountancy (GAAP compliance) Partners: Hub Consortium Members, ChemAxon, DNDi, MMV, Sandler Center… CDD SAB: Christopher Lipinski PhD, James McKerrow, MD PhD, David Roos PhD, Adam Renslo PhD, Wes Van Voorhis, MD PhD
  4. CDD Experienced Team Innovates and Executes Barry Bunin, PhD (Pres. & Cofounder as first Eli Lilly EIR) Libraria (CEO, Pres.-CSO), Arris Pharmaceuticals (Sr. Scientist), Genentech, UC Berkeley (Ellman), Columbia University, author. Moses Hohman, PhD (Director Software Engineering) Northwestern Assoc. Director of Bioinformatics, Thoughtworks, Inc., U of Chicago (PhD), Harvard ( magna cum laude, Physics) Sylvia Ernst, PhD (Director Community Growth & Sales) Left 800-lb Gorillas: Accelrys-Scitegic, MDL-Elsevier-Beilstein Peter Cohan (BOD & Overall Sales Strategy) Symyx (VP Bus Dev & President-Discovery Tools), MDL (VP Customer Marketing), www.secondderivative.com, author. Omidyar Network, Founders Fund, & Lilly (BOD observers) WSGR (Corporate Counsel), Rina Accountancy (GAAP compliance) Partners: Hub Consortium Members, ChemAxon, DNDi, MMV, Sandler Center… CDD SAB: Christopher Lipinski PhD, James McKerrow, MD PhD, David Roos PhD, Adam Renslo PhD, Wes Van Voorhis, MD PhD